.Dangers
of Dietary Isoflavones, Soy and Others
at levels above
those found in traditional diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
http://www.mayanmajix.com/soy.html -
Dangers of Soy
“Soy
- Abundance Of Health Hazards”
http://www.mayanmajix.com/soy01.html
May
2003 – November 2004
April
2006
Page 1 of - over 144 pages
. .
Cargill
has received “self-determined” GRAS status, not approved U.S.A. FDA GRAS status, for its
AdvantaSoyTMClearTM isoflavone supplement to be used as an additive for
beverages, nutrition bars, yoghurt, meal replacements and confections. The summaries of abstract studies, the
evidence, attached here give ample demonstration of the real dangers to the
general public of adding phytoestrogens (isoflavones) to common foods, as well as, exposing the very real
dangers imposed onto the general public by the soy and the food industries “Self Regulation”, “Economic Self
Interest”, and the risks of abandoning “The Precautionary Principle.”
.
This collection of scientific research
abstracts, ( the
evidence ), out of a continually growing list of hundreds available,
represents a fast growing body of scientifically creditable medical and dietary
research on the many serious health hazards, (including cancer), of putting soy
& soy ingredients in our food supply.
Almost all of the abstracts presented here are also published in
the NIH Medline PubMed data base and are representative of current and past
research from around the world, in 2004 and going back to 1916, 1911, even as far back as 1907. Full
research is also available via these abstracts.
Notice some of the research studies include those from the US Department
of Energy and NCTR which are Federally operated and funded, and other very
reputable research institutions from around the world.
.
This collection of scientific
research abstracts is from well-designed studies, from around the world,
conducted in a manner which is consistent with generally recognized scientific
procedures & principles which show that there does exist significant scientific agreement among experts
from around the world, [qualified by
scientific training, experience and expertise], a very strong statistically significant association of harm to
human and to animal health from the consumption of soy, soy protein, and soy
estrogen ingredients in our food supply and an INCREASED RISK
of a variety of cancers and other major and life threatening health problems,
referred to in this body of evidence as “Hidden Harm,” which includes but not
limited to this list of known, “ignored”
and still denied “Side-Effects”
of ... endocrine disruption ... thyroid suppression ...
immune system suppression ... heart disease ...
liver disease ... leukemia, (IAL) ...
Cancer(s) - breast, bone, uterine, liver, colon, pancreas, thyroid etc ...
Arthritis ... infertility / lower sex drive ...
growth problems ... subtle changes in sexually dimorphic
behaviors ... Osteoporosis ... learning
disabilities & Alzheimer’s / Parkinson’s Disease from Brain /
Nervous System damage ... chromosome fragmentation & errors in
chromosome orientation ... DNA damage ... “DEATH”. Note: Genistein in soy is also a Topoisomerase II-poison pages, 32, 44. Read testimonials on pages 15 to 20, 100,
116, 117, and 122 – 126.
.
See
page 121 for a more detailed list of “ignored”
health hazards associated with eating soy, which are also
being called “adverse medical and developmental conditions.” For
taking “legal action”
against the manufactures and sellers of soy products regarding developing these medical
problems while eating soy, see pages 120, 4-7, 10, 18 and 97-119. For some of the history on how
and why soy got into
our food supply, and why soy is still in our food supply, see pages 4, 5, 11, 12,
18, 105. Now, see the “evidence,” the proof of harm, which includes but is not limited
to the over 205 scientific research abstracts from around the world between 1907 into 2004 on pages 29 - 84 and also read
what everyone can do about it on pages 118 and 142. This research paper
will reveal and easily prove why the addition of isoflavones to common foods have always posed a clear & extreme danger to the public and should not be allowed.
.
It
has been argued that high levels of soy isoflavones such as genistein, daidzein
and genistin in Asian diets protect the inhabitants of
Isoflavones
China (1990, 1999 survey), (5.) 3 mg/day
Japan (1996 survey), (2.) 10 mg/day
Japan (1998 survey), (3.) 25
mg/day
Japan (2000 survey), (4.) 28 mg/day
In Japanese subjects receiving adequate iodine, Soy still causes thyroid suppression after
3 months use,(6.)
38 mg/day
In American women, causing
hormonal changes, after 1 month, (7.) 45 mg/day
AdvantaSoyTMClearTM. 30-50 mg / 100 g serving … / 2
- 2 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
.
.
As evidence on toxicity of soy isoflavones
accumulates, warnings have begun to appear in the popular press. An article
appearing in the Washington
Post Health Section
was titled: “You have to be soy careful:
tofu and similar foods may be beneficial, but some experts fear that too much
could be unsafe.”(8.) Writing for the New York Times, health columnist Marian Burros published
the following: “Against the backdrop of
widespread praise ... there is growing suspicion that soy-despite its
undisputed benefits-may pose some health hazards ... Not one of the 18
scientists interviewed for this column was willing to say taking isoflavones
was risk free”(9.) .
.
References: ( Parts of page 1 are from an earlier draft version. Up-date at … http://www.westonaprice.org/soy/dangersisoflavones.html
)
1. Nutrition during Pregnancy and Lactation.
California Department of Health, 1975.
2.
Fukutake M, Takahashi M, Ishida K, Kawamura H, Sugimura T, Wakabayashi
K. Quantification of genistein and genistin in soybeans
and soybean products. Food Chem
Toxicol 1996;34:457-461.
3.
Nagata C, Takatsuka N, Kurisu Y, Shimizu H. Decreased serum total
cholesterol concentration is associated with high intake of soy
products in Japanese men and women. J
Nutr 1998
Feb;128(2):209-13.
4.
Nakamura Y, Tsuji S, Tonogai Y. Determination of the levels of
isoflavonoids in soybeans and soy-derived foods and estimation of
isoflavonoids in the Japanese daily intake. J AOAC Int 2000;83:635-650.
5.
This exhaustive study of Chinese diets found that legume consumption
ranged from 0 to 58 grams per day, with a average of 13 grams
According
to the researchers, about 2/3’s of this was supplied by soy beans, giving average
consumption of about 9 grams of soy
products per day. Chen J,
Campbell TC, Li J, Peto R. Diet, Lifestyle and Mortality in China. A study
of the characteristics of 65
counties. Monograph, joint publication of Oxford
University Press, Cornell University Press, China People's Medical Publishing
House, 1990. Isoflavone content is estimated be about 3 mg per day
based on an average amount of 30 mg total isoflavones per 100
grams of tofu. USDA-Iowa State University Database on the Isoflavone
Content of Foods 1999.
6. Y
Ishizuki, et al, “The effects on the thyroid gland of soybeans administered
experimentally in healthy subjects,” Nippon
Naibunpi
Gakkai Zasshi 1991, 767: 622-629
7.
Cassidy A, Bingham S, Setchell KD. Biological effects of a diet of soy
protein rich in isoflavones on the menstrual cycle of
premenopausal women. Am J Clin Nutr
1994;60(3):333-340.
8. Washington Post Health Section, January
30, 2001.
9.
Burros M. Doubts Cloud Rosy News on Soy. New York Times, January 26, 2000.
As you read through this paper you
will soon discover,
Soy acts like a fertilizer
and fertilizes, feeds, cancer cells causing them to grow.
.
“... Propaganda
... “is the systemic propagation of a given doctrine or of
allegations reflecting its views and interests; material disseminated by the
advocates of a doctrine." The promotion of soy as a miracle food has been both
systematic and reflective of the doctrine of the food industry — that imitation
foods are good for us and traditional foods are unhealthy. The soy campaign is, in fact, a case study in the use of propaganda to
promote commercial interests,” ( Profits from a known & proven poisonous
food ingredient above the Health, Safety and the Well-being of everyone, world
wide ). Quote from … http://www.mercola.com/2001/apr/7/soy.htm
.
.
“Strong and Wrong”
- virus - “Weak and Right” ... The soy industry ... one of the world’s
most wealthy, influential and powerful business organization ... funds millions of dollars of soy research
and advertising each year in order to increase sales; so, what chance is
there for discoverers of soy toxins to get funding to continue their
work of exposing the truth about the many serious and deadly
health hazards of eating soy ??. Soy Politics, new link at … http://www.soyonlineservice.co.nz/05soypolitics.htm
… the old link at … http://www.soyonlineservice.co.nz/politics.htm …
The soy industry's
influence over the media, research institutions and government agencies is
strong. The goal of soy research is to
boost industry profits and the US economy.
.
“Education
is the most powerful weapon you can use to change the world,” by Nelson
Mandela. We, the
volunteers of Soy Online Service, uncover soy’s many serious &
sometimes deadly health hazards, as well as, soy industry’s intense influence
and political corruption that allows soy and soy ingredients in our food supply
to illegally stay on the market world wide.
.
“… All Truth Passes Through 3 phases: first it is
ridiculed; next it is violently opposed; and finally it is accepted as self evident …”, by the German philosopher Arthur Schopenhauer.
.
i i i , i i i , i i i , i i i , (+) i i i - See page 96 for abstract
summary.
-
http://www.soyonlineservice.co.nz/articles/Soyatox.htm
.
1994 “Purification
and physico-chemical characterization of soyatoxin, a novel toxic protein
isolated from soybeans (Glycine max),” – Vasconcelos
I.M., Trentim A, and others, Arch Biochem Biophys 1994 Aug 1 312:2 357-66, Department Of
Biochemistry and Molecular Biology, Unversidade Federal do Ceara, Fortaleza,
Brazil.
...
/ 3
- 3 –
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Also see pages 84, 127, “…It may not be coincidental that Pancreatic Cancer recently moved up to 4 th
place as cause of cancer deaths in men & women in the USA as consumption of
soyfoods in the US has increased. In the
1970’s and 1980’s, several researchers studying protease-inhibitor damage on
the pancreas noted that pancreatic cancer had moved up to 5 th place,
wondered if there might be a soybean-protease inhibitor connection…”, taken from page 43 of the Weston A Price Foundation’s 50 page petition of objection to the FDA,
June 14, 2004, at ( # 2004Q-0151 ), regarding a request by The Solae Corp. asking
FDA to issue a Health Claim saying that soy prevents cancer
The Doctor Within
“The Magic Bean? Soy-Taintly Not !.”
. http://thedoctorwithin.com/index_fr.php?page=articles/magic_bean.php .
Old Link … www.thedoctorwithin.com/articles/magic_bean.html .
Soy
protein isolate is big business. One of
the biggest producers of soy protein is Protein Technologies International
of St. Louis, a DuPont subsidiary. (Finucan) We
must appreciate the brilliance of taking a waste product from an already
extremely processed food source and getting the majority of the population to
think of this dead by-product as a food staple.
In general, the vast majority of soy
products today are examples of a super-refined
artificial food, devitalized, and devoid of nutritional value. It is a true food of commerce, as Royal Lee would have said.
THE GOLDEN BEAN
Why doesn't anyone know about all this ??. How can we go from a perfect food to a
non-food and have 99% of the population know nothing about it ??. When this familiar scenario appears, it
always means one thing: time to follow the money.
In that regard, here's some interesting
statistics: Today, the soybean is America's 3rd
largest crop (harvesting 73.8 million acres in 2002), supplying more than 50 percent of the world's soybean demand.
(Soy Stats Reference Guide, 1999, also Bernard)
.........................................................
US Soybean US
Soybean US
Soybean
Production in millions of bushels Crop Value Oil Production
1940 - - - 78 1971 - - - $ 3.56 billion 1996 - - - over 6 million
tons
1971 - - - 1,176 2002 - - - $15 billion (1997 Soy Stats)
2002 - - - 2,730
- source: 2002 Soy Stats Reference Guide
By 2002, crop value is $15 billion per year. Keep
in mind, this figure does not take into account the retail market of the dozens
of finished soy food products sold in supermarkets. That total probably approaches $100 billion. It's not just in the soyburgers and margarine
and cooking oil and soy milk. For well
over 20 years, in many, many other processed foods, we often get a …
…
HIDDEN SURPRISE …
See a list of foods with soy ingredients
... pages 18 and 121
...........................................................................................................................................................................
i ; i
“The Truth About
The Drug Companies” ... $ ... http://www.nybooks.com/articles/17244?email
... 12 page essay
— by Marcia Angell, a former
editor of the New England Journal Of Medicine.
— The
— "... The most startling
fact about 2002 is that the combined profits for the 10 drug companies in the Fortune 500
($35.9 billion) were more than the profits for all the other 490 businesses put together ($33.7 billion).(12) ...”.
--- “... When I say this is
a profitable industry, I mean really profitable. It
is difficult to conceive of how awash in money big pharma is ...". ...
/ 4
-
4 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“The Newest
Research On Why You Should Avoid Soy”
by Sally Fallon and Mary Enig PhD., 2000
... http://www.mercola.com/article/soy/avoid_soy.htm
“... The
propaganda that has created the soy sales
miracle is all the more remarkable because, only a few decades ago, the soybean
was considered unfit to eat - even in
“... However, the
pictograph for the soybean, which dates from earlier times than the Chou
Dynasty, indicates that it was not first used as a food ; for whereas the pictographs for the other four grains show
the seed and stem structure of the plant, the pictograph for the soybean
emphasizes the root structure.
Agricultural literature of the period speaks frequently of the soybean and
its use in crop rotation. Apparently the soy plant was initially used
as a method of fixing nitrogen”. 13.
“... The soybean did not serve as a food until the
discovery of fermentation techniques, some time during the Chou Dynasty. The first soy foods were fermented products
like tempeh, natto, miso and soy sauce. At a later date, possibly in the 2nd
century BC, Chinese scientists discovered that a purée of cooked soybeans could
be precipitated with calcium sulfate or magnesium sulfate (plaster of Paris or
Epsom salts) to make a smooth, pale curd - tofu or bean curd. The use of fermented and precipitated soy
products soon spread to other parts of the Orient, notably
“... The Chinese did not eat unfermented soybeans as they
did other legumes such as lentils because the soybean contains large quantities
of natural
toxins or "anti-nutrients". First among them are potent enzyme
inhibitors that block the action of trypsin and other enzymes needed for
protein digestion ...”.
“... These inhibitors are large, tightly folded proteins
that are not completely deactivated during ordinary cooking. They can produce
serious gastric distress, reduced protein digestion and chronic deficiencies in
amino acid uptake. In test animals,
diets high in trypsin inhibitors cause enlargement and pathological conditions
of the pancreas, including cancer ...”. 14.
“... Soybeans also contain haemagglutinin, a clot-promoting
substance that causes red blood cells to clump together. Trypsin inhibitors and
haemagglutinin are growth inhibitors.
“... Soy advertisers selectively claim lower rates of
reproductive cancers for Japanese and Asians eating soy, while ignoring the
fact that these same people also have much higher rates of cancer of the ...
esophagus ... stomach ... liver ... pancreas ... and thyroid ... particularly
as soy causes these same types of cancers in laboratory test animals. 37-39
“... Japanese and
Asians eat soy in very small amounts, as a condiment (a
seasoning),
not as a protein substitute, not as a replacement for animal foods
!. 42.
“... Soy protein
has not been given
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods ... / 5
- 5 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy Warning
Labels, For Medical Reasons
Two of The USA F.D.A.’s Expert Scientists
Protest Soy Approval.
Researchers and “Whistle-blowers” Daniel Doerge Ph.D and Daniel Sheehan Ph.D are two of the
U.S.A.’s Food and Drug Administration’s,
FDA, expert scientists on soy who signed a Feb. 18, 1999 letter of protest to
the FDA when the FDA granted soy a “health claim” in 1999. This letter expresses serious concerns
regarding the perceived safe use of soy, if soy was to be granted a “health
claim,” and includes 26 documented scientific referenced studies, (Abstracts),
that show a link between eating soy and serious health problems.
In their
letter of protest they said, “… it is inappropriate to allow a health claim for
Soy Protein Isolate, SPI, … it could be misinterpreted, … the health
labeling of SPI for foods needs to be considered just as would the addition of
any “Estrogen” or “Goitrogen” to foods, which are bad ideas. Estrogenic and goitrogenic drugs are regulated by the FDA, and
are taken under a physician’s care.
Patients are informed of risks, and are monitored by their physicians
for evidence of toxicity.
No similar safeguards are in place for foods, so the public
will be put at potential risk from soy isoflavones in SPI without adequate
warning and information...”
See
letter ... http://abcnews.go.com/onair/2020/2020_000609_soyfdaletter_feature.html,
article withdrawn,
and at ... http://www.mercola.com/2001/jun/30/soy_fda.htm
, use
Google Search for more.
Toxic Load means that the
risk is a function of dose length, dose
strength, and of the physical condition of the consumer. Reference:
“The Dose Makes the Poison: A
Plain-Language Guide to Toxicology”, 2nd Edition, © 1996, by M. Alice Ottoboni,
“Chemical
Carcinogens", © 1976, by The American Chemical Society,
“Principles
of Toxicology”, by Casarett and Doull,
“The
Basic Science of Poisons”, © 2001, Casarett, Amdur, Klaassen, Doull
The Soy industry has “applied twice” and was “turned down twice(1979, 1999)” on both of its applications for “GRAS
(Generally Recognized As Safe)” status for Soy Protein BECAUSE of Soy’s carcinogenic properties;
also Soy has not been given
“Pre-market Approval” for its use in our
food. It is not even legal to add it to
our food.
In addition, Soy is in breach of, in violation
of - “WHO/CODEX - Food Safety Standards.” P.S. To add insult to injury, Soy fails the 1958 “Delaney Amendment” to the USA’s FDA
Reg.’s which prohibits the use of any food additive if it is found to cause
cancer in any animal species or in man, at any dose level ... http://www.pcdf.org/meadows/delaney.htm
. Add these 6
strikes against the Soy industry to the growing list of ignored
side-effects on page 1., and you have millions of crime scenes. In the US FDA’s “Poisonous Plant Database” … http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY ... Soy, and
(Flax and Linseed), and (Canola, and
Rapeseed) are all listed as “poisonous plants”, and the FDA recommends
that if you are injured by them, to contact your local “Poison
Control Center” in your area, (at ... http://www.aapcc.org/.),
or call 911. Soy acts like a fertilizer
and fertilizes, feeds, cancer cells to help them grow. ... / 6
- 6 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“Why” Soy Protein
- Is In Breach of - WHO/Codex Standards
… http://www.soyonlineservice.co.nz/Refs/Codex.htm …
old Link
… http://www.soyonlineservice.co.nz/articles/Codex.htm
… New Link to new website format
World Health Organization, WHO
WHO/Codex General Standards for Soy Protein Products
WHO/Codex Standard 175-1989
6.3 (c) When
tested by appropriate methods of sampling and examination, the product shall not contain other poisonous substances
which may represent a hazard to health.
WHO/Codex General Guidelines for the Utlization of
Vegetable Protein Products (VPP) in Foods CAC/GL 4-1989
4.1 VPP intended for human consumption should
not represent a hazard to health.
Annex
. The raw materials from which VPP are produced may
contain naturally occurring toxic or anti-nutritional factors. Some of these
factors may still be present in VPP after processing. In the light of the above
observations it becomes important that prior to the use as human food, VPP be
subjected to adequate testing to demonstrate safety and appropriate nutritional
quality. A distinct VPP needs to be tested pursuant to this guideline only
once, that is, to obtain a toxicological and nutritional profile for VPP. Prior
history of safe use may be taken into account in the evaluation of a novel VPP
proposed for general consumption, but this alone is not necessarily sufficient
to preclude adequate pre-clinical testing by currently available, more
objective, laboratory animal feeding studies, and, where applicable, studies
using human volunteers.
1.4 Toxicological Safety:
The safety of the VPP should
be predicted from information concerning methods of production, chemical and
physical properties. This should be supported, where necessary, by safety data
using laboratory animals.
2.4.1 Subacute Toxicity Studies:
The purpose of these studies
is to delineate the toxic potential of VPP and to elucidate such problems as
species sensitivity, the nature of gross and micro-pathological changes and the
approximate dose level at which these effects occur. They also provide
guidelines for the selection of dosage for chronic toxicity tests and any
functional or biochemical studies that may be necessary.
2.4.1.3 Length of Study:
Subacute
toxicity feeding trials should be at least three months duration.
2.4.2 Other Studies:
Following an appraisal of the
source and the method of manufacture of the VPP together with the results of
nutritional and subacute toxicity studies, the need for further studies
including chronic, reproduction, teratogenic and mutagenic studies will be
evaluated.
SOS comment: There is clear evidence that Soy Protein does
not meet WHO/Codex Guidelines.
... / 7
- 7 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandonging “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
The Isoflavones Present
In Soy Protein Induce-(cause):
( “Why” Soy Protein - Is In Breach of -
WHO/Codex Standards )
Continued
Subacute toxicity … http://www.soyonlineservice.co.nz/04thyroid.htm .
Phytoestrogens Anti-thyroid agents
Chronic toxicity … http://www.soyonlineservice.co.nz/articles/Brain.htm
. Abstracts (3)
- i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
1996 “Association
of mid-life consumption of tofu with late life cognitive impairment and
dementia: the Honolulu-Asia Aging Study,” - White
L, Petrovich H, and others, Fifth International Conference on Alzheimer's Disease, #487, 27
July 1996, Osaka, Japan.
— There is evidence suggesting
that estrogens modulate neural and synaptic plasticity during aging.
— “... We found an association
of consistently high levels of tofu consumption in mid-life with low cognitive
test scores (p=0.02) and (independently) with Alzheimer's disease in late
life, controlling for all
other relevant variables. The odds ratio
for AD in persons who reported eating tofu at least twice weekly was 2.4 (95%
CI 1.14-5.09), compared with persons reporting tofu consumption rarely
or never ...”.
Reproductive
toxicity … http://www.soyonlineservice.co.nz/04infertility.htm
. Phytoestrogens,
Nature’s contraceptives.
Reproductive system damage … Phytoestrogens
can make animals intertile, what about People ??.
Teratogenic effects
… http://www.soyonlineservice.co.nz/articles/Bdefects.htm . The Dominion,
Embryo, monster making
… Deformities Found in
Sons of Vege Mums.
Mutagenic effects … http://www.soyonlineservice.co.nz/articles/metzler.htm
. Immune System Effects
… http://www.soyonlineservice.co.nz/04immunefunction.htm
.
( 9+ ) Abstracts - i i i , i i i , i i i , i i i -
Causes cancer cells to grow
... DNA damage ... chromosome fragmentation and errors in chromosome
orientation.
The potential oral
hazard of phytoestrogens - has long been known - by food
regulator such as the FDA. During his presentation at the 3rd
International Phytoestrogen Conference in 1995, FDA regulator Dr Michael Bolger made
direct reference to the soy isoflavones causing infertility, uterine
hypertrophy and testicular atrophy in rodents, liver disease and reproductive
failure in cheetah and menstrual cycle effects on women. ( Also, see bottom of page 8 … the TRUTH
about Fermented Soy ).
*
* *
Two Books
That Expose and
Unmask The Corrupt Soy Industry
http://www.wholesoystory.com/About_the_Whole_Soy_Story.html
...“The
Whole Soy Story,” by
Kaayla T. Daniel, MS, Ph.D, CCN. With 30
chapters & 7 subsections, new 2004 book tells the whole truth about
soy, its many very serious health hazards, & real history of how soy got
into our food supply. It
is all about fact and not fiction.
This book presents and interprets the often contradictory evidence on
soy and disease to determine what studies are valid, which justify hope, which
are mere hype – and why, with a FAQ section.
“It
is child abuse to feed a baby soy formula.”
http://www.doctorsaredangerous.com/index.html
... “Take
Control of Your Health & Escape the Sickness Industry,” by Elaine Hollingsworth reveals in
Chapter 9 ... “Soy - The Abominable Bean”, at ....
http://www.doctorsaredangerous.com/ChapterNine.pdf
… just how we’ve been all conned because of corporate greed, bad science, and
regulatory misconduct by most governments around the world. It explains how eating soy foods produces
many very serious health hazards like cancer, it destroys your thyroid and
leaches calcium from your bones (osteoporosis), and also why “It
is child abuse to feed a baby soy formula.” All this and a
whole lot more. ... /
8
- 8 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
.
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to Reduce
Breast Cancer ?. Fish Oil is a Must
... http://www.mercola.com/2002/jun/5/fish_oil.htm
...
“... Differences
in the actions of Omega-3 fats and Omega-6 fats have been observed on
these genes.
** Omega-3
fats ... have been described to "reduce" cancer cell
growth, ( includes Fish Oils ) ...
* Omega-6 fats ... have been found to "cause"
cancer growth ...”.
*Omega-6 oils,
“... I strongly recommend avoiding ... sunflower ... corn ... “Soy” ... safflower
... “Canola” ... or products that contain these oils. In other words, no hydrogenated or partially hydrogenated
fats including ... margarine ... vegetable oil ... (vegetable)-shortening ...
etc. These oils are full of Omega-6 fats and will only worsen
your Omega-6 / 3 ratios ...”. Soy – (Flax, Linseed) – (Canola, Rapeseed) – are all listed in the
FDA’s Poisonous Plant database ... http://www.cfsan.fda.gov/~djw/plantox.html
. Over 685 scientific research abstracts
listed, out of over 1,000 known, going way back to 1850, proving serious harm
to human - animal health. (over 400 such abstract do exist for soy alone since 1907) Soy industry, food, health food
industries and governments have all been lying to us, pages 5, 6. 7, 113, 119,
121 ... abstracts pages 29 – 96
**Omega-3 oils,
(EPA,
DHA),“...
Acceptable oils are high quality ... extra virgin “olive oil” ...
“Coconut oil” ... “avocados” ... “organic butter” ...
better yet ... “Grass-fed organic butter ...”. (
“...
Generally our diet contains far too many omega-6 fats. Experts looking at the dietary ratio of
omega-6 to omega-3 fatty acids suggest that in early human history the ratio
was about 1:1 ... ... Currently most Americans eat a
dietary ratio that falls between 20:1 and 50:1.
The optimal ratio is most likely closer to the original ratio of 1:1 …”.
“...
For most of us, this means greatly reducing
the omega-6 fatty acids, & increasing
the amount of omega-3 fatty acids we eat ...”.
* *
*
.
Fermented Soy ...
Cancer Chemo-preventative ??
( Also
see pages 5 - 7, 10, 21, 29, 31, 32, 36, 42, 48, 52, 65, 72, 74, 75, 81, 101,
104, 109, 113, 118, 121, 142 )
. http://www.mercola.com/2004/aug/4/fermented_soy.htm
.
The soy industry’s claim that "...
fermented soy products like, Natto, Tempeh, Soy Sauces, Fermented tofu and
soymilk, and Miso are particularly rich in the isoflavone aglycones, genistein
and daidzein, which they say are believed to be cancer chemo-preventatives
...". The
implication by the soy industry is that these natural occurring chemical
compounds are good, for instance in cancer prevention, if they are consumed in
natto or miso (not exactly staples of Western diets), when in fact it is
exactly these same chemicals that are the endocrine disrupters which have so
alarmed many independent scientists around the world. Genistein
in particular is fingered, was proven, by FDA scientists, S.S. Kuan, O.J.
Francis, et al, at the FDA's NCTR and the New Orleans Poisonous Plants laboratories, way back in 1991, as carcinogenic, estrogenic, cytotoxic, anti-thyroid, on
research lasting over 3 months, Page 126…(see 10
th World Congress Report, pg. 527)
But, what soy industry also KNOWS but still NEVER tells people when
claiming fermented soy is chemo-preventative is ... it all depends on the dose
levels of these chemicals, [even
though this principle has been a basic teaching since 1500's in
the science of Toxicology-(see research by the famous Swiss physician “Paracelsus” ... http://www.mindfully.org/Pesticide/Paracelsus-Dose-ToxicologyOct01.htm
.).]. At high chemotherapy dose levels genistein
& daidzein kills cells, and cancer cells. But the dose levels needed for
this chemotherapy type responses, (the soy industry claims to happen from
eating fermented soy), are also at dose levels far beyond
those achievable at dietary consumption levels. So, their claim of
chemo-preventative has no relevance at all when it comes to consuming
these chemicals at dietary levels in soy or vitamin supplements. As the
scientific research clearly demonstrates, at dietary levels genistein and
daidzein disrupts
and damages the immune and hormone system, and also causes a variety of health
problems including a variety of cancers, and DNA damage.
This claim by the soy industry clearly
shows the fallacy of seeking and promoting short-term results and ignoring
long-term consequences, administering drugs to people who don't need them, a
case of hidden mass medication upon the unsuspecting and unknowing public.
Fermentation only lowers the toxin levels,
it doesn’t eliminate them. To get the lowest toxin level, fermentation needs to
be at least 2 years, as Asians do, not like in
- 9 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
.
Sunlight Actually
Prevents Skin Cancer
http://www.mercola.com/2002/apr/3/sun_prevents_cancer.htm
“... Skin cancers are more likely related
to the large distortion most people have in their Omega-6 and Omega-3
fat ratios ... The likeliest
mechanism for a protective effect of sunlight is vitamin D, which is
synthesized by the body in the presence of Ultraviolet B, UV-B ...".
"...
Most people believe that sun exposure causes cancer. Nothing could be further from the truth. As this study published in the prestigious Cancer
journal, March 2002, indicates, exposure
to sun actually decreases
cancer rates ...”.
“...
So the solution is not to splatter sun block on. Sun block can be quite “toxic",
and should be avoided by most people ...”
“...
The sensible approach would be to limit sun exposure so you never get
sunburned. It
is sunburn in conjunction with — excess
omega-6 fats — that increases your risk of skin cancer. But even with the potential increase in skin
cancer, most skin cancers are relatively benign when compared with breast,
colon, and prostate cancers that lack of sun exposure is associated with ...”.
“...
So you can't have it both ways. Avoid
the sun and don't change your diet and you will lower your risk of skin
cancer, but increase your risk of far more common and deadlier cancers
... So why not change the fat content of your diet and use sensible sun
exposure guidelines and reap the benefits of sunlight ?.
Diet and Sunlight
Linked to Breast Cancer Risk
http://www.mercola.com/2002/jan/26/diet_sunlight.htm
"...
As for the role of sunlight, researchers found an association between latitude
and breast cancer, suggesting that higher UV-B
exposure was protective. UV-B
rays spur the production of vitamin D in the body,
it is likely the vitamin is behind the association he found in this study. Other research suggests vitamin D may help
ward off cancer ...".
“...
Women who limit
their exposure to sunshine
will have lower vitamin D levels and an increased
risk of breast cancer, in addition to an increased risk of osteoporosis
...".
* * *
References ...
Want to Reduce
Breast Cancer ? Fish Oil is a Must ... http://www.mercola.com/2002/jun/5/fish_oil.htm
British Journal of Nutrition, April 2002,
vol. 87, no. 4, pp.
281-289(9), Abstract.
British Journal of Nutrition, March 2002,
vol. 87, no. 3, pp 193-198(6), Abstract
Sunlight Actually
Prevents Skin Cancer ... http://www.mercola.com/2002/apr/3/sun_prevents_cancer.htm
Cancer, March 2002;
94:1867-75
Diet and Sunlight
Linked to Breast Cancer Risk ... http://www.mercola.com/2002/jan/26/diet_sunlight.htm
Cancer,
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods ...
/ 10
- 10 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy - “Weakens” - Your Immune System
http://www.mercola.com/2002/jun/8/soy.htm
Known still Ignored
This 2002 study funded by
“United Soy Bean Board” and the
“Illinois Council on Food &
Agricultural Research”
Hormone-like compound found in Soy
products, including Soy-based infant formula & menopause remedies, may
impair immune function
When mice were injected with the “plant
estrogen" genistein, which is found in Soy products, levels of several immune cells dropped
and the thymus, a gland where immune cells mature, shrank.
Of course, people eat rather than inject
Soy products, but the thymus also became smaller in mice that consumed genistein in their
diet. This is particularly concerning, researchers say, since the resulting
blood levels of genistein in the mice were lower than those reported in human
babies fed soy formula.
A few reports from the late 1970's and
early 1980's suggested that a soy-based diet impaired infants' immune
functions. About 15% of infants in the
Proceedings
of the National Academy of Sciences , (
................................................................................
Dr. Mercola’s Comment:
It is quite amazing that this study was actually published, as the findings
were quite (-)negative for soy and yet it was funded
by the United Soybean Board and the
Amazing, it seems that eventually the
truth on soy does reach the service, despite the massive funding by the edible
oil industry to convince the public that soy is the greatest thing that ever
hit the planet to improve your health. See
the abstract of the 1997 Lancet
study at ...
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9217716&dopt=Abstract
.
1997 “Exposure of
infants to phyto-oestrogens from soy-based infant formula,” – Setchell K.D., Zimmer-Nechemias L., Cai
J., Heubi J.E.,
Lancet. 1997 Jul 5;350(9070):23-7.,
... ( See bottom of page 36 )
The abstract above shows that Soy has glycosides
of genistein and daidzein or plant based chemicals that
mimic estrogen. They
possess a wide range of hormonal and non-hormonal activities. The daily
exposure of infants who consume soy formulas was 6-11 times higher than adults consuming soy foods.
The blood concentration of these hormones
was 13,000 to 22,000 times higher than estrogen in the blood. The
authors of this article speculate that this concentration may be sufficient to
exert biological effects, whereas the contribution from breast-milk or
cow-milk is negligible.
Soy
formula is one of the worst foods that you could feed your child. Not only does it have profoundly adverse
hormonal effects as discussed above, but it also has over 1000 % more aluminum
than conventional milk based formulas
I don't recommend either, but if one, for
whatever reason, cannot breast feed, then non-soy Carnation Good Start until six months and Carnation
Follow-Up after that seem
to be the best commercial formula currently available. The milk protein is
hydrolyzed 80% that tends to significantly decrease its allergenicity.
Continued ... ... /
11
- 11 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy “Weakens” Your Immune System
http://www.mercola.com/2002/jun/8/soy.htm
... Continued ...
It is also important to note that when
breast-feeding it is wise to avoid drinking milk as it has been shown for
several decades that the milk will pass directly into the breast milk which can
cause potential problems in the infant.
Related Articles:
Pregnant
Women Should Not Eat Soy
, at ... http://www.mercola.com/1999/archive/pregnant_should_not_eat_soy.htm
.
Soy
Formulas and the Effects of Isoflavones on the Thyroid , at ... http://www.mercola.com/2000/feb/13/soy_thyroid_disease.htm
.
How
Safe is Soy Infant Formula?
, at ... http://www.mercola.com/2001/jun/13/soy_formula.htm
.
Experts
Dispute JAMA Soy Infant Formula Study , at ... http://www.mercola.com/2001/sep/15/soy_formula.htm
.
Soy
Milk Is Safe! That Is What the Formula Industry Says , at ... http://www.mercola.com/2001/aug/25/soy_milk.htm
.
Australian
Pediatric Soy Protein Formula Policy , at ... http://www.mercola.com/2001/sep/22/soy_protein_formula_policy.htm
,
* * * * * * * * *
... More On
Soy’s Fraudulent History ...
Also see pages 4, 5, 6, 7, 18, and 105, as
well as ( 12, 100, 107, 121 )
Concerns about the potential carcinogenesis
of modern soy is not new.
1.) The Committee for Food Safety was worried
about it in 1966, the definitive textbook “Chemical Carcinogens” published by the American Chemical
Society in 1976 had a chapter titled “Plant Carcinogens” that
identified soy isoflavones as “known”
carcinogens.
2.) The “Life Sciences” Committee of FASEB in its 1978-9 “Evaluation of Soy Products
for Human Consumption”
for the Food and Drug Administration (SCOGS-101 under contract to the FDA #
223-75-2004) declined GRAS determination because
of the risks of carcinogenic ... nitrosamines
... lysinoalanines ... and
nitrite
occurring during the modern processing. (Not to mention the other
scientifically documented natural occurring carcinogenic chemicals is soy
called genistein and daidzein ).
3.) Moreover in 1999, an application by Archer Daniels Midland
Corp for GRAS determination of GRAS (GRN
00001) for isoflavones was declined due to the failure of the applicant to
reveal health risks.
4.) Soy protein does not have GRAS determination.
Soy protein was slipped into the food chain about 1959 even though the developmental research
(funded by ADM and Mead Johnson) demonstrated that it caused serious
infertility problems in laboratory rats and their offspring. This is recorded in a series of papers in the
“Journal of Nutrition” by Schultze, Liener et al in the 1950's
The only evaluation was in 1979 by the “Life Sciences” section of FASEB, and soy protein failed because of
the risk of nitrosamines forming in the heat treatment. FASEB
assumed the heat treatment was removing the natural poisons and did not evaluate their safety at
all. You will find a fuller discussion
of GRAS in the
Home Page of www.soyonlineservice.co.nz
"Trouble for Soy Protein",
including Dr Fitzpatrick's opposition to the grant of health claim labelling by
the FDA. The material in … http://www.soyonlineservice.co.nz/06doses.htm
… "Doses Simplified" gives an idea of how toxic the levels of
isoflavones are in the products.
5.) http://www.soyonlineservice.co.nz/04cancer.htm
. (Phytoestrogensn – Cancer) ... Why
does the Soy Online Service
Webmaster, Dr. Mike Fitzpatrick PhD, an environmental toxicologist and a
scientist of recognized international expertise, expresses the opinion that “the
lowest form of life on the planet” is anyone who claims soy and isoflavones
are protective against cancer ... without also revealing ... that there are numerous
world wide creditable scientific research studies, (including those by US
Federal Government research institutions), which show that Soy ... 1.) damages DNA, chromosomes and the immune system, ... 2.) cause cancer, ...
3.) cause existing cancer
cells to multiply, ...
4.) cause non-cancerous
tumors to turn cancerous ??. Because, those that make this claim are guilty of giving false hope to
millions of people, with or without cancer, by withholding and suppressing this
valuable life-saving scientific information.
But even far worse than all this, those that make this claim are placing
innocent consumers at a far greater risk of contracting this same horrendous
disease that all consumers are afraid of and are desperately trying to avoid. I
agree.
Also
see pages 12, and 98 – 105 – 119 – 127
...
/ 12
- 12 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy Online
Service Answers 5 Questions
An Introduction: The History Of How Soy Got Into Our Food
Supply
... This 2nd
Reply is 1st ...
----- Original Message -----
From: Valerie
& Richard James , Soy Online Service
To: Gerald
Hernesmaa
Sent:
Subject: Re: Re: Urgent ... Can you help please ??
... Need answers to these 5 questions !!
OK Gerald. In brief. ( An
Introduction ... A plausible conspiracy theory consistent with known facts and the USA
National Security Agency minutes.)
In the
early 1950's the British Government was
hoping to rebuild the empire that it had largely lost as a result of WW-2. The principle used was
the one that had worked in the past.
That is, to have colonies producing raw materials for shipment to
For West
Africa, it became known as the
British Groundnut. Scheme ... grow peanuts and ship them
to the
The CIA did not want a strong
So a connivance was fabricated. Undercut the British peanut protein with
cheap
What a coup for the
There was an added bonus.
The
It may not be all correct, but it hangs together and is historically
correct per time line. And it was postulated by a very competent
biochemist in 1993.
Cheers Dick
............................................................
Remember ... To
protect your health and your families health, be sure to read the ingredient
labels on all of the foods you buy.
Also ... be
very, very careful about eating in “Restaurants” and in “Hospitals”,
as they do not list the ingredients in their foods.
Vegetable oil
... has not been real vegetable oil, made from a varitey of vegetables, not including
soy, since the early 1970’s. Since then
it is ... either “Soy” or “Canola” or both, and
it rarely includes cottonseed, peanut, palm oil. Genistein in soy is proven to be and is
classified as a Topoisomerase II-poison.
Note: Make sure the label on your
vitamins, minerals, medications says ...
contains no Soy ... or ... contains no Soy ingredients ... / 13
- 13 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
(Also see ... http://www.proparanoid.com/truth.htm
... “25 Ways To Suppress Truth, The Rules of Disinformation”)
5
Questions The “Answers” with this 1st
reply
----- Original Message ----- -----
Original Message -----
From: "H. Michael Sweeney", hms@proparanoid.com From: Valerie & Richard James , Soy Online Service
To: "Gerald Hernesmaa" healthwise933@shaw.ca To: Gerald Hernesmaa
Sent:
Subject: Re: Urgent ... Did you receive my package containing the Sent:
Soy Research Paper ... and the $10.00
to these 5 questions !!.
From: Mr. H. Michael Sweeney ... Yes, thank you. Just
picked it up today. (mailed him a copy of our Soy Research
paper and Soy Pamphlet).
The newsletter will be mailed tomorrow, barring unexpected disaster,
like runing out of ink !.
The soy material is
another matter. Not quite up my ally, but
very interesting topically for a number of
reasons you
may not have
considered. I'm throwing these ( 5 questions ) at you for your comments, in case you know
the answers.
They are probably too left field and may leave us both wondering.
Questions &
Answers:
From: Richard and Valerie James ... Hi Gerald,
Ok, Will try to keep it
short. Jimmy Hoffa is not our line !, But the C I A theory is a possibility.
1) Who knew all the negative ramifications and
when did they know it? If they knew it
in the late 1950's and 60's, I'm thinking
that may be why Jimmy Hoffa got into Soy
beans in a big way, I'm
thinking he likely partnered with CIA to do it (see next.).
The Soy Online Service
Answer ... The original projects to extract the protein from left- over soymeal
after oil removal were done with funding by ADM
and Mead Johnson in the early 1950's.
Results of rat -feeding trials were published in subsequent issues of
the Journal of Nutrition, by M.O. Schultz et al, in around 1953/4/5.
We have those papers but they are a rotten layout and not suitable for
putting on a website as they have no opening abstracts. The rats had troubles creating baby rats
and the few baby rats they created had poor reproductive performances. A first clue that this stuff crosses
generations. It would take us a while to get to the papers
for more detail and we are flat-out with other urgent stuff. As we recall some work was at
Subsequent work was at both
The scientists all knew they were not removing the
“estrogens” or “sterols.” That is published in a paper by Eldridge,
Nash and Wolf in the 1967 Jour of Food Chemistry. We
have that here too. In fact Walter J Wolf would be high on our list of most
harmful scientists in history. There also
was research in
All this is in published academic papers.
The first published analysis of estrogenic content of soy protein was by Murphy in 1982, though the UK Central Veterinary lab did
analysis in 1980 and compared estrogenic effects of human-use soy...16 ppb DES and 24 ppb DES in the two
samples tested....with diethylstilbestrol.
You can get that in … http://www.soyonlineservice.co.nz/04soy&DES.htm
..."Soy and DES" .
(and
also at … http://www.soyonlineservice.co.nz/Refs/murphy.htm
)
...
/ 14
- 14 -
Dangers of Dietary Isoflavones
at levels above those found in traditional diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Questions & Answers: Cont
...
2) What
would be the effect of Soy on someone who was taking
anti depressants (SSRIs)? This is a CIA developed product class which I describe as an enabler for select
mind control applications. Yes, it can
be beneficial for those with true mental imbalances, a normal person it makes
them more susceptible to various MC attacks and programming methods. Mn These products went into development in
the mid 1960's, if I remember my dating.
Prior to that, CIA was experimenting with a
WIDE range of products, including LSD (for the same purpose) and I'm wondering
if that included Soy extracts or other Soy products, byproducts, or compounds.
Answer ... Don't know Nor does anyone else we are aware of.
3) In like
manner, what would be the effect of Soy be on a schizophrenic or paranoiac
personality? Would it elivate, agrivate, or excentuate, be neutral, or reduce
or impede the symptoms? Same reason for
asking, since certain forms of MC targeting seems to selectively focus on
individuals with these personalities.
Further, targeting on 'normal' people long term produces these
personalities in the end, especially when augmented with SSRIs.
Answer ... It would, based on the rat research that is published, send them
into low-earth orbit. A major windup and
is confirmed by numerous parent-anecdotes.
The aggressiveness has been almost beyond control. Here's a recent one
...
2003 “The soya isoflavone content of rat diet can
increase anxiety and stress hormone release in the male rat,” – Hartley D.E., Edwards J.E., and others, Psychopharmacology
(Berl) 2003 Apr 5; 167(1):46-53. Epub 2003 Mar
05., Psychopharmacology Research Unit, Centre for
Neuroscience, Hodgkin Building, Kings College London, Guy's Campus, SE1 1UL,
London, UK. david.2.hartley@kcl.ac.uk
We had it in our family too. Teenagers at a time of hormonal change are
most vulnerable. In fact the
peripubertal time is a risk age that was identified by Clarkson, Anmthony and
Hughes et al in a paper published in 1995.
4) Where
does Eli Lilly stand
with respect to
anything Soy - any participation, studys, products, etc? They were very connected to early MC work and
to the Bush family.
Answer ... Eli Lilley is not into
soy, soy supplements or drugs with pseudo-soy
chemicals.......as far as we know
5) Are you aware of any military or intelligence
community projects or research involving Soy for any purpose, and if so, what
was its nature? Can you point me to
references that discuss it?
Answer ... Not as far as we know.
Professor XXXXX told us in a 1998 personal conversation that
the US Army knew soy protein was toxic when they put it into C-rations
in the Korean war...but as the users had a low survival outlook anyway, a bit
more risk was deemed acceptable (That it not quotable without Irv's permission as he was on the
Army's project).
Privately
we often wonder if the Gulf War syndromes may have been connected.!
This
is all top-of-the head stuff. More detail would take us hours which we do not
at present have.
Cheers
Dick.
Mr. H.
Michael Sweeney ends with saying ... ”Regardless of, if you have any answers
on the above that I might find useful, I have a couple of other people who
would likely be quite interested in your material, and who might be better
suited to helping to promote
it on their Web sites. If you DO
have some useful answers, that list will be longer. I'll make gentle inquiries and suggest they
contact you directly. One is local, and
I'll give them the packet, (soy research paper and soy pamphlet), you sent me
to reduce your expenses (lot of work
put into it, too - great job!) ...”
Best , Harry .
...
/ 15
- 15 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
----- Original Message -----
From: Valerie
& Richard James , Soy Online
Service
Cc: Mike
Sent:
Subject: Re: 3 generations of soy problems
Hello Tina. We help the www.soyonlineservice.co.nz
webmaster with his mail. Thank you for your input, though we are really shocked
to hear this. However it is not the
first time by any means, and by 1993 we knew that the
reproductive system effects of soy in the diet could carry down at leat three
generations. A CANADIAN ASSOCIATE OF OURS HAD FOLLOWED IT
IN DAIRY COWS FOR FIVE GENERATIONS BY 1995.
For the good of future generations of your family you should all try to avoid all exposures to estrogenic
foods. ( See SOS guidance ) ... and this
includes soy oil, alfalfa, and flaxseed. Brassicas should be thoroughly cooked
Your comments about "news" are a bit sad as, without
being totally paranoid we can guarantee that most major media have an embargo on criticising
this industry. We know of countless
tales that have been written by journos who think as you do, but have ended up
in the Editor's/ Publishers " too hot " bins. Text is the gray stuff
between adverts......and if an industry
like this blacklists a publication, the effects on revenue
can be horrendous. They are also
adept at using the threat of
lawsuits. The one at … http://www.soyonlineservice.co.nz/articles/Sanitarium.pdf ... “Teams of
Lawyers", (and also at … http://www.soyonlineservice.co.nz/files/Havoc.htm
), is just a small example which happened to be reported in a gossip paper. Sanitarium was the pinch-hitter for Protein
Technologies, the DuPont subsidiary.
They lost but it cost the radio station's insurers a bunch to make it go
away. Most insurers want to approve
publication if the word "sue" etc is mentioned. As most editors ask that the industry be
interviewed too, the industry threatens to sue. We know it as "censorship
by insurance clerk." If you go to HOT
READING just regard it as a miracle that that much got published. Before the NZ scientists got started stuff
like that did not exist.
Do your best locally, Best wishes, Valerie.
..............................................................................................................................................................................
----- Original Message -----
From: Tinawinwood@XXXXXX
Sent:
Subject: 3 generations of soy problems
I have been researching the negative effects of soy for several reason, for
the past week i have been on a soy based diet and have found that i gained 9 lbs in 7 days, highly unusual for
my body, i went online to research if the change in my
diet could be the cause and found the information about the ability of soy to depress the
thyroid gland, needless to say I have removed the soy in my diet and am hoping to reverse this sudden weight gain, more importantly my vegan daughter gave
birth to a son this october who was born with hypospadias,
she researched the cause and only found information saying that the pesitcides
in her vegan
diet may have been the cause, we now know have
reason to believe it was her daily consumption of soy products, her baby was scheduled to be weaned this week from breast milk &
be put on soy
formula, of course now that will not be the case, my
son who was allergic to milk when he was born 29 years ago was put on prescription soy formula and is going for surgery
to have his enlarged breasts reduced, my
doctor never told me it was not tested back then, and my daughter peditrician
just told her last week that soy formula was okay for our grandson....i
am so surprised this soy issue is not in the forefront of
the news and tests need to be done,
Sincerely, tina winwood
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods ...
/ 16
- 16 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
----- Original Message -----
From: Valerie
& Richard James , Soy Online
Service
Sent:
Subject: Re: thank you!
Dear Heather,
We are terribly sorry
to read this. If you would like to help
on a cold winter eve, one way is to forward by email your letter and our reply
to every State medical association. They
mostly have sites with a list of Staff and Officials. Ask them to pass it to their County branches
and advise all members. Just a 5% hit
rate may prevent some harm somewhere.
We've done that before but got absolutely no feedback, so have no
idea if it made any difference.
Best Wishes, Valerie.
.............................................................................................................................................................................
----- Original Message -----
From: Walter
Aaron Foster
To: webmaster@soyonlineservice.co.nz
, Soy Online Service
Sent:
Subject: thank you!
Thank you for the service you
are doing by having this site. As the mother of a wonderful 4 year old boy,
I'd like to add my 2 cents regarding the extreme health hazards of soy. My son was born with a
“3rd degree hypospadias” which required 10...yes ten surgeries to
correct. He had
the worst hypospadias a male can have, where his urethra's opening appeared at the base of his
genitals. How did
this utter nightmare occur? Well, little did I
know that the DAILY tofu and soy milk I was drinking for the past
decade ( I was foolishly a vegan ) was highly
estrogenating my already estrogenated body. Healthy women make enough estrogen
as it is. The phyto estrogens disrupted my fetus'
development. I have met other women who had son's with
hypospadias and they ate soy daily all during pregnancy. Enough said.
Thank you for helping
the public realize how detrimental soy
is, and that it's really just junk food. Regards,
Heather
...........................................................................
“Hypospadia”
http://www.amershamhealth.com/medcyclopaedia/Volume%20IV%202/HYPOSPADIA.asp
“… A congenital malformation
of the urethral groove and urethral canal, resulting in an abnormal opening on the ventral penile
surface. On physical examination, the external urethral meatus can be found
anywhere on the ventral aspect of the penis, from just proximal to its normal
location to the perineum. It is associated with failure of normal testicular
descent and malformations of the urinary tract … ”.
http://health_info.nmh.org/Library/HealthGuide/IllnessConditions/topic.asp?hwid=rt1129
“…
because of abnormalities in their chromosomes or endocrine system
… ”.
See below, just some of many abstracts ... DNA damage ... Chromosome fragmentation &
errors in Chromosome orientation at … http://www.soyonlineservice.co.nz/04immunefunction.htm … and … NCBI, PubMed, the USA’s National Center for Biotechnology Information. Over 15 million citations for biomedical articles from the present
and going back to the 1950’s ( National Library of Medicine and National
Institutes of Health ).
1989 - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2548712&dopt=Abstract
.
1998 - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9729267&dopt=Abstract
.
2002 - http://www.giftinfo.uni-mainz.de/EXCLI/volumes/Vol1/2002volume1pp8-14.pdf
.
...
/ 17
- 17 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to know why
you don’t hear about the many health hazards of Soy ??
Also see
pages 105 - 113 of this 144 page Soy Research Paper
Example, this 2003 news
research story below from ... http://alberta.indymedia.org/news/2003/03/6009_comment.php
provides
a clear and
undeniable example of
the documented proof
of the attempted
and mostly successful suppression & cover-up of the truth about the
harmful side-effects to human and animal health of BGH growth hormone in milk. The same type of cover-up around the world can
easily be proven with respect to the information about the harmful side-effects
of eating Soy. This
news article and legal ruling shows why 99% of the research and its information
on the many health hazards of eating soy does not reach or get past the news
media in order to inform the public.
Also see ... “Hidden
Danger in Your Milk ?” at ... http://www.foxBGHsuit.com
, BGH growth hormone.
Some of us know very
well that the goal of the news media is about KEEPING NEWS AWAY FROM people. In the former
Appellate Court
Rules Media Can “Legally Lie”
http://alberta.indymedia.org/news/2003/03/6009_comment.php
By Mike
Gaddy, Published 02. 28. 03 at
On
On Aug. 18,
2000, a 6-person jury was unanimous in its conclusion that Akre was
indeed fired for threatening to report the station's pressure to broadcast what
jurors decided was “a false, distorted, or slanted” story about widespread use
of growth hormone in dairy cows. Court didn’t dispute the heart of Akre's
claim, that Fox pressured her to broadcast a false story to protect the
broadcaster from having to defend the truth in court, as well as, suffer the
ire of irate advertisers.
Fox argued from the first, and failed on three separate occasions, in front of
three different judges, to have the case tossed out on the grounds there is no
hard, fast, and written rule against deliberate distortion of the news. The
attorneys for Fox, owned by media baron Rupert Murdock,
argued the First Amendment gives broadcasters the right to lie or deliberately
distort news reports on the public airwaves.
In its six-page
written decision, the Court of Appeals held
that the Federal Communications Commission position against news distortion is
only a "policy," not a promulgated law, rule, or regulation.
Fox aired a report after the ruling saying it was "totally
vindicated" by the verdict.
......................................................
See
... http://www.hairyeyeball.net/jotbook/archives/001530.html
"...
In other words, in a layman's reading, Fox did not order her to do anything
illegal, only something that Fox could get its license yanked for by the FCC.
Well, hmmm, actually, come to think of it, that means there's no
"law" against it, only a regulatory "rule," and not an
"adopted rule."
“The Florida
whistle-blower's law at ...
http://www.flsenate.gov/Statutes/index.cfm?mode=View%20Statutes&SubMenu=1&App_mode=Display_Statute&Search_String=&URL=CH0448/Ch0448.HTM
, ... specifies
that an employee must have been order to break a "law, rule, or
regulation." Once again, fine
slicing and dicing,
... / 18
- 18 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to know “why” you don’t hear about the
many health hazards of Soy ??.
Also see
pages 105 - 113 of this 144 page Soy Research Paper
…
Continued …
Appellate Court Rules Media Can Legally Lie
... Continued ...
----- Original Message -----
From: Valerie & Richard James , Soy Online Service
To: Gerald
Hernesmaa
Sent:
Subject: Re: “News Media Can Legally Lie” ... The Suppression of Truth Is Now
Legal ... how convenient !!.
Hi
Gerald
We have known this for years.... and in NZ
we suffer from Heinz controlling our biggest media empire....Wilson and Horton
...with 42 papers, 53 radio stations and the two biggest magazines in this
little country. Camille
Guy suffered from exactly
the same treatment here. Lost her job, was sent to
"Conentry" and blackballed.
Dick.
...
and ...
Hi
Gerald
Further to our reply to this (topic), a
Dick.
............................................................................................................
Einstein said, “...the world is a dangerous place to live in, not because of the people who
are evil, but because of the people who don’t do anything about it...”.
Soy, The Deadly Stealth Ingredient
Remember to read the ingredient
labels on all of the foods you buy !!.
If Soy Isn’t Harmful, Why Is It Hidden ??.
Found in thousands of ... processed ...
canned ... frozen ... junk foods ... Vitamins ... Prescription medications ...
etc.
“Hidden soy”
... where you wouldn't
expect to find it, as in ... up to 90 percentage of hospital foods feed to staff, patients,
including cancer patients ... even protein drinks served to cancer patients in
hospitals and in cancer clinics ... vitamins, minerals, Medications ... liquid in vitamin E capsules ... almost all
candy ... regular ice cream ... all regular salad dressings ... mayonnaise ...
a variety of restaurant foods including burgers, french fries ... Kentucky
Fried Chicken ... store baked chickens ... hamburger meat in food store meat
dept.’s ... some canned tuna’s ... airline foods ... large percentage of baked
goods like bread, cakes ... fruit drinks ... lard, margarine ... dairy ...
whipped cream ... breakfast cereals ... potato, corn chips ... hot dogs ...
Baby foods ... diet beverages ... Campbells Soups ... pet foods ... etc.
“Undeclared soy”
... Soy that is not
listed on the food or medication ingredient labels, as in ... Prescription medications ... vitamins for
children and adults ... MSG is from soy... food manufacturers can be careless and
neglect, or purposely neglect to mention soy, or the ingredients have changed and the label hasn’t
caught up ... cross-contamination caused by soy used in other products produced
at the same facility ... soy dust in the air from the bulk bins at health food
stores ... trace amount of soy that has rubbed off from a variety of cardboard
packaging, (food, non food packaging), in which soy protein isolate has been
used as a bonding ingredient.
The 8 “Aliases”
of soy - (“False names - also known as”) ... Commonly used ingredients that people don't
recognize as being soy are ... “Vegetable oil” ... or ... “Vegetable Shortening”
... or ... “textured vegetable protein“ ... or ... “bouillon”. These may also contain canola, or both soy
and canola. Then there is ... “MSG” which is made from soy ... http://www.truthinlabeling.org/ ... Truth
In Labeling. Three more
names are “Natural Flavoring” ...
“Vegetable Flavoring” ... “Hydrolyzed
Protein or Vegetable Protein” .
Note: Make sure the label on your
vitamins, minerals, medications says …
contains no Soy … or … contains no Soy ingredients ... / 19
- 19 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to know “why” you don’t hear about the
many health hazards of Soy ??
Also see
pages 105 - 113 of this 144 page Soy Research Paper
... Continued ...
----- Original Message -----
From: Valerie
& Richard James , Soy Online
Service
To: Randy
Kay and Beatrice Ekwa Ekoko
Cc: Mike
Sent:
Subject: Re: precocious puberty ?.
Hello Beatrice.
We help the webmaster with his mail. Yes, she has been subjected
to those risks......in fact both your daughters have been. “Health
If you go to ... www.soyonlineservice.co.nz Hot
Reading, you will see an internet link to an essay by the American Enocrine
Society called ... "Pseudo Puberty" at ... http://www.emedicine.com/ped/topic1881.htm#
. At page 4 they say that excess soy consumption can cause
it. Our webmaster believes that exposing
children to any estrogens is excessive.
We suggest you write to your Minister of Health expressing your
dismay.
Good Luck Valerie.
................................................................................................................................................
----- Original Message -----
From: Randy
Kay and Beatrice Ekwa Ekoko
To: webmaster@soyonlineservice.co.nz
Sent:
Subject: precocious puberty?
Hello.
from the age of 18 months, when my daughter weaned herself,
up until I discovered a breast bud on her chest at age 51/2 years old, my
daughter drunk
soy “milk”. Could this be the reason she started to develop
breasts? She is
also very tall for her age(8)
She now takes Traditional Chinese Medicine to slow down the
development.
I also fed my younger
daughter soy products from age one,
when I was advised not to feed her diary products as she had chronic ear
infections. She stopped at 18 months
when we moved and her ear infections cleared up. I am worried that she too might show signs of
early puberty like her sister.
Looking forward to hearing from you.
Sincerely,
Beatrice Ekoko
.......................................................................................................................................................................................
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods ...
/ 20
- 20 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
----- Original Message -----
From: Valerie
& Richard James , Soy Online Service
To: Sheila
Sent:
Subject: Re: soy/low thyroid connection
Hello
Sheila
We help the webmaster with his mail. It's
good to hear a few doctors are aware of the dangers. Most conventional ones
still have the notion that if they have not heard of something, therefore by
definition it cannot exist. The God Complex.
This is the definitive work from the FDA's
own scientists ...
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9464451&dopt=Abstract
.
1997 Anti-thyroid
isoflavones from Soybean; isolation, characterization, and mechanisms of
action, Biochem Pharmacol - Nov 1997;
54(10):1087-96,
You are recounting classic secondary signs
of hypo-thyroidism and your physical and mental health are likely to improve if
you avoid all soy (see SOS Guidance) Also be wary of isoflavone supplements,
flaxseed, alfalfa and soy oil, all of which are estrogenic and can destabilize
your thyroid
Good Luck, Valerie
..............................................................................
----- Original Message -----
From: Sheila
To: webmaster@soyonlineservice.co.nz
Sent:
Subject: soy/low thyroid connection
I
drink about a glass to two glasses of soy milk a day and eat tofu about twice a
week. I was diagnosed
with hypothyroidism through my acupuncturist in January of 2004 and am on something called Thyrostim. My
hair was falling out prior to being put on Thirostim Also, I was depressed and
got hot/cold flashes. I am thirty one years old.. My acupuncturist has also put
me on a strict alkalizing diet plan, but soybeans and tofu are OK with
this diet plan, he says.
I even decided to go Vegetarian a month ago. Even though my hair has stopped
falling out, I feel moody and depressed and have gained weight and am not even
eating that much.
Today
I visited a natural alternative healing doctor and he told me to stop the Soy altogether because of my thyroid problem. He
told me to type in the “Dangers” of Soy on the internet and here I am. This is all
news to me. I am actually shocked. I am now going to dump out my soy milk in
the fridge and cupboards. I will report back on how I feel in a couple of weeks
after being off Soy completely.
Sheila in the
....................................................................................................................
i ; i
Bush’s “Sound
Science”, (Is No Science At All), Turning a deaf ear to reality — by David Schubert, July 9, 2004,
Organic Consumers Association ... http://www.organicconsumers.org/corp/bushscience071604.cfm
.
“... Much of the justification
for this repression of scientific communication falls under the “Orwellian concept of sound science,"
which is clearly understood by the scientific community
to mean the “misrepresentation” of scientific data to reflect the administration's political and social agendas ... This political manipulation of U.S.
science began well below the level of public awareness within days after the
current administration took office, 2001. Highly respected scientists on dozens of
advisory committees were replaced with individuals who promote
"sound science" as defined by industry and the religious
right.
... /
21
- 21 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy
The Miracle Food or Pandora's Box?
Researched by Gerald, volunteer,
Health Action Network Society
Pamphlet http://www.hans.org/
What has science been telling us?
... What does history reveal?
"Current evidence for
the beneficial
effects of soy requires a full
understanding
of potential adverse effects as
well."
Dr. D. Doerge, scientist from the
The genistein in soy is a Topoisomerase
II-poison
Quoted
here are many of the scientific research studies on soy spanning the years 1907 through to the present.
Updated: June 2004
Soy Blocks
Vitamin and Mineral Absorption
Studies indicate
that soy (organic and non-organic) causes Endocrine-disrupting
isoflavones, genistein and daidzein
increased
requirements for vitamins E, K, D and B12. are
naturally
occurring goitrogenic components found in
Phytic acid from
SPI blocks the absorption of essential soy.
In vitro and in vivo studies document isoflavones
minerals and
creates deficiency symptoms of calcium, inhibiting the synthesis of
estradiol and other steroid
magnesium, copper,
molybdenum, iron, manganese and hormones.
Infertility, reproductive problems, thyroid and
especially zinc -
in the intestinal tract. (2) This may be liver
disease due to dietary intake of isoflavones have been
contributing to
the early onset of osteoporosis in
starting there as
early as age 20 versus age 34 in the cheetah,
quail, pigs, rats, sturgeon and sheep. (1.a,3,6)
organs,
particularly the thyroid gland and pancreas, and 100 grams of soy protein - the
maximum suggested
caused increased
deposition of fatty acids in the liver. cholesterol
lowering dose - can contain almost 600mg of
isoflavones,
an undeniably toxic amount. Only 45 mg
Soybeans have one
of the highest phytate levels of any of
isoflavones taken daily for one month, in pre-
grain or legume.
Phytates in soy are highly resistant to menopausal
women, reduced hormones needed for
normal
phytate-reducing techniques such as long, slow adequate
thyroid function. In some of the women, these
cooking. Only
long periods of fermentation will greatly effects
lingered for 3 months after soy consumption was
reduce soy's
phytate levels, but will not eliminate them. discontinued.
.
Soy Has Natural
Toxins or Anti-nutrients The Swiss Health Service, in 1992, estimated that 100
grams
of soy protein provides the estrogenic equivalent of
Soybeans contain
potent enzyme inhibitors that block the one
birth control pill. (1.a,3,6)
action of trypsin
and other enzymes needed for protein
digestion. These
inhibitors are not completely deactivated Asians
throughout the world have high rates of thyroid
during ordinary
cooking. They can produce serious gastric cancer.
Japanese researchers reported in 1991 that
distress, reduced
protein digestion and create chronic defi- consumption
of as little as 30 grams or 2 tablespoons of
ciencies in amino
acid uptakes. In test animals, diets high in soybeans
per day for only one month resulted in a
trypsin
inhibitors also caused enlargement and pathologi- significant decrease in
thyroid-stimulating hormone.
cal conditions of
the pancreas, including cancer. (1,3,6,8) Japanese and Asians
eat soy in very small amounts, as a
condiment
(seasoning), not as a protein substitute and not
Soy contains
haemaglutinin, which is a clot-promoting as a replacement
for animal foods. (1.a,3,6,8)
substance that
causes red blood cells to clump together,
setting the stage
for clogged arteries and stroke. Continued ...
... / 22
- 22 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy
The Miracle Food or Pandora's Box?
Health Action Network Society
Continued
Processing of
Soy Adds Even More Toxins Soy Infant
Formula
Much soy is acid
washed in aluminum tanks, leaching high Daily exposure of infants to
isoflavones in soy infant
levels of
aluminum into the final product. Nitrites, potent formula is 6 to 11 times higher on
body-weight basis than
carcinogens, are
formed during spray-drying, and toxic the
dose that has negative hormonal side effects in adults
lysinoalanine is
formed during alkaline processing. Arti- consuming
soy foods. ( 1.a,3,6,8,9 )
ficial
flavourings, particularly MSG are added to SPI
and
textured
vegetable protein (TVP) products to mask their Approximately
25 per cent of bottle-fed children in the
strong,
"beany" taste and to impart the flavor of meat. (3,9) receive
soy-based formula - a much higher per cent than in
other
parts of the Western world. Toxicologist Dr Mike
Cancer and DNA
Damage Fitzpatrick
estimated that infants exclusively fed soy
formula
receive the estrogenic equivalent (based on body
Soy is
carcinogenic, causing cancer cells to grow and non- weight) of
at least 5 birth controls pills per day. By
cancerous tumours
to turn cancerous. (3,6,8) Thousands of contrast, almost no phyto-estrogens have been
detected in
women are now
consuming soy in the belief that it protects dairy-based infant formula or in
human milk, even when
them against
breast cancer. Yet in 1996, researchers
found the
mother consumes soy products.
that women
consuming soy protein isolate (SPI) had an
increased
incidence of epithelial hyperplasia, a condition In the 1986 Puerto Rico Premature Thelarche
Study, the
that preceded
malignancies. Genistein and diadzein most significant
dietary association with premature sexual
stimulate breast
cells to enter the breast cancer cycle.(
3,6,8) development
was not chicken, as the press reported, but soy
Since 1989, soy has been known to cause DNA
damage, infant
formula. (1.a)
chromosome
fragmentation and errors in chromosome
orientation. (3,6,8) Pregnant women who eat soy products Early maturation in girls is
frequently an indicator of
are at an
increase risk for breast cancer. (3,4,6,8) problems
with their reproductive system in later life,
including
failure to menstruate, infertility, breast cancer
Soy advertisers
collectively claim lower rates of and
possibly uterine cancer. (3,6,8) Problems in both
sexes
reproductive
cancers for Japanese and Asians eating soy, associated
with soy-based infant formula later in life also
while ignoring
the fact that these people also have much include
extreme emotional behaviour, immune system
higher rates of
cancer of the esophagus, stomach, liver, problems,
pituitary insufficiency, irritable bowel syndrome,
pancreas and
thyroid, particularly as soy causes these same asthma, thyroid disorders
including thyroid problems in
types of cancer
in laboratory test animals. (1,3,6,8) babies
and infantile leukaemia. (1.a,3,6,8,9,10)
.
Brain and
Nervous System Damage Thyroid
Problems
Genistein destroys
the myelin sheath surrounding the nerves, Soy
also contains goitrogens - substances that depress
spinal cord, and
brain cell tissue...one cause of Alzheimer’s- thyroid
function. Diffuse goiter and hypothyroidism
Parkinson’s
disease, & learning disabilities ADD-ADHD.(3,6,8) appeared in some of the
subjects and many complained of
fatigue,
lethargy and constipation, even though their intake
Japanese Americans
living in Hawaii show a significant of
iodine was adequate. (3,6,8,9,10)
statistical
relationship between two or more servings of tofu
a week and
accelerated brain aging (atrophy). In another Soy Warning
Labels, for Medical Reasons
study, those
eating tofu in mid-life experienced greater
incidence of
Parkinson’s / Alzheimer's disease, dementia, In 1999, USA's FDA ignored two of their
own expert research
lowered cognitive
function, and looked older in later life. scientists,
Daniel Sheehan, PhD and Daniel Doerge, PhD,
(1.a,3,6,8,9) who
expressed serious concerns regarding the perceived
safe
use of soy, if soy was to be granted a 'health claim'. In
their
letter of protest they said, “…it is inappropriate to
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
Continued ... ... / 23
- 23 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy
The Miracle Food or Pandora's Box?
Health Action Network Society
Continued
.
Soy Warning
Labels, For Medical Reasons References: continued
Continued
allow a health
claim for SPI….. it could be (4.)
misinterpreted….
the health labelling of SPI for foods need newsletter "eHealthy News you Can
Use" - www.mercola.com
to be considered
just as would the addition of any (In
'search', type: soy)
‘estrogen' or
'goitrogen' to foods, which are bad ideas.’
Estrogenic and
goitrogenic drugs are regulated by the FDA,
(5.) The 1958 "Delaney Amendment" to the
and are taken
under a physician's care. Patients are prohibits the use of any food additive if
it is found to cause
informed of
risks, and are monitored by their physicians for cancer
in any animal species or man, at any dose level.
evidence of
toxicity. No similar safeguards are in place for - http://www.pcdf.org/meadows/delaney.htm
.
foods, so the
public will be put at potential risk from soy
isoflavones in
SPI without adequate warning and (6.) Soy
OnLine Service, SOS, are a small group of private citizens
information.” (7) Vetetable oil is no longer vegetable oil, it from
is either soy,
canola, or both. (1a,3,4,6) They
have no industry connections and are not funded by any
outside
interest groups. Their mission is to uncover truths about
The soy industry
“applied twice and was turned down soy
and to provide consumers with an alternative opinion to the
twice” on both of
its applications to the
“GRAS (Generally
Recognized as Safe)” status for soy - http://www.soyonlineservice.co.nz/
.
protein because of
soy’s carcinogenic properties and
soy has not been
given “Pre-Market Approval” for use (7.)
in our food. Also, soy is in breach of, in violation of, Concerns. Researchers, Daniel Doerge
PhD and Daniel Sheehan
“WHO / CODEX” Food
Safety Standards.” It is not even PhD are two of
the
legal to add it to
our food (1a,b,3,4,6)
experts on soy who signed a Feb. 18, 1999 letter of protest
documenting
26 referenced studies that show a link between
“Toxic
Load” means that the risk is a function of dose eating soy and serious health
problems.
length, dose
strength, and of the physical condition of the - http://www.mercola.com/2001/jun/30/soy_fda.htm
,
consumer. Reference: "The Dose Makes the
Poison: A
Plain-Language Guide to Toxicology," 2nd edition, (8.) PUBMED - www.ncbi.nlm.nih.gov/PubMed/; with hundreds of
© 1996, by M. Alice Ottoboni. (1a,3) scientific
abstracts showing serious health hazards from eating soy.
DNA damage: “Inhibitory
effects of the tyosine kinase inhibitor
A comprehensive
information package on soy is available genistein on
mammalian DNA topoisomerasell.” (Sept. 15, 1989)
from The Health Action Network Society - www.hans.org Causes cancer cells to grow: “Phytoestrogen interaction with
estrogen receptors
in human breast cancer cells.” (Nov. 1978)
Abstracts … http://www.soyonlineservice.co.nz/07abstract.htm
.
References: Osteoporosis
… http://www.soyonlineservice.co.nz/03toxins.htm
.
Infertility
… http://www.soyonlineservice.co.nz/04infertility.htm .
The small numbered footnotes 1-72
correspond to the studies,
Birth
Defects … http://www.soyonlineservice.co.nz/04birthdefects.htm
articles and the legislation referenced in (1.a) by Weston
A. Cancer … http://www.soyonlineservice.co.nz/04cancer.htm
.
Price
Foundation. - www.westonaprice.org . Also see its DNA damage … www.soyonlineservice.co.nz/04immunefunction.htm
.
update (1.b) Both are © 2000 by
(1.a.) "Newest Research on Why You Should Avoid
Soy" (9.) The Doctor Within ... “The
Magic Bean? Soy-Taintly Not !,”
- www.mercola.com/article/soy/avoid_soy.htm
, and -
http://thedoctorwithin.com/index_fr.php?page=articles/magic_bean.php
.
Soybean-Bad - http://www.rogerkyoung.com/old/soybean.html
.
(1.b.) "Tragedy and Hype: The 3 rd
International Soy
Symposium," (10.) “FDA Poisonous
Plant Database” Research on the toxic properties
- www.westonaprice.org/soy/tragedy.html
. and
effects of plants & plant parts. Going way back to 1907, see # 184
Soy
in search, http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY
.
(2.) The Gerson Institute,
California 92101,
Phone; 619 685 5353 - www.gerson.org/ . (11.) “Uterine Adenocarcinoma in Mice Treated
Neonattally with
Genistein,” June 1, 2001, Cancer Research, Abstract,
(3.) Soy – Abundance of Health Hazards, - http://cancerres.aacrjournals.org/cgi/content/abstract/61/11/4325
.
- http://www.mayanmajix.com/soy_summary.pdf
… one page Summary
- http://www.mayanmajix.com/soy01.html
… Full 144 page HTML … End … ... / 24
- 24 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/,
( Also see … http://www.mayanmajix.com/soy.html -- Health Articles
- Soy )
. Soy
- Abundance of Health Hazards
(( healthwise933@shaw.ca ))
.
Gerald & Deanna - (
Deonaa )
.
Soy - Vegetable Protein % Chart
“Nutritive Value of American
Foods in Common Units ”
USDA Agriculture Handbook No. 456
.
Fruits
Lemons ... … . … … 16 Strawberry …
8 Apricot …
8 Watermelon …
8 Papaya … 6 Grapefruit .
… 5
Honeydew melon …
10 Blackberry …
8 Grape ..
… 8 Tangerine ..
… 7 Pear …
… 5 Pineapple…
… 3
Cantaloupe … … … 9
Cherry .. … … 8
Vegetables
Spinach
… … … … … … 49 Cauliflower … … … …
40 Green beans ... … …
26 Tomatoes … ... …
18
Watercress
… … … … … 46 Mushrooms … … … … 38
Dandelion Greens …
24 Beets … … . … … 15
Kale
… … … … … . … … 45 Chinese Cabbage.
… … 34 Green Pepper …
. … 22 Pumpkin … ... … 12
Broccoli
… … … … … … 45 * Lettuce … Parsley .. … 34
Artichokes … … . …
22 Potatoes .. ... … … 11
Turnip
Greens / Collards 43 Zucchini …
. … . … … 28 Celery / Eggplant …
21 Sweet Potatoes .
… 6
Legumes
Grains Nuts & Seeds
Soybean sprouts . … … 54 Wheat
germ … . … 31 Pumpkin
seeds … … 21
(Pick non-Soy type) Mungbean sprouts ..
… 43
Soybean curd (tofu) … 43 Wheat,
hard red … 17 Walnuts, black … …
13
Soy Flour .. … … … … 35 Wild
rice … . … … 16 Sesame
seeds … .. … 13
Soybeans ... … … … … 35 Buckwheat
… .. … 15
Almonds …
… … … 12
Soy sauce .. … … … … 33 Oatmeal
… .. … … 15 Cashews
… … … … 12
Broad beans …
.. … … 32 Millet
… … . … … 12 Filberts
... … . … … 8
Lentils … … … .. … … 20
Barley …
... . … … 11
Split peas …
… .. … … 28 Brown
rice … .. … 8
Kidney beans ...
. … … 26
Navy beans …
.. . … … 26 Note … Protease
( Enzyme ) inhibitors in Soy - block protein digestion, pg. 84
Lima beans …
… … … 26 Remember,
Soy is a very Low quality
protein, and it is not very well
Garbanzo beans ...
.. … 23 absorbed by the body. The actual amount of usable protein in soy is
about
50 % of what it says to the Left, which is then from 16 % to 27 %.
.
More - Safe - Alternatives
Instead
of Cow’s milk or Soy Milk … try using “Almond milk” -- “Oat
milk” -- “Rice milk”. Best to add “Organic” Maple Syrup
to Rice milk because that will help make up for its’ low mineral
content. This is especially very, very important for
… babies … children … pregnant
women … cancer patients … the elderly. Note: MSG - is also made from soy … http://www.truthinlabeling.org/.
.
Be
careful … be careful !! … Be careful I said … Be careful !!. “Vegetable oil” has not
been real Vegetable Oil, that is, actually made from a variety of vegetables, NOT
including soy, since early 1970’s. Since then, it has been
either “Soy” or “Canola” or both,
and it rarely includes cottonseed, peanut, palm oil. Genistein in soy is proven to be and is
classified as a Topoisomerase
II-poison. Use safe Omega-3 oils
… cold press 100 % Extra Virgin Olive Oil … Avocado … Coconut Oil … Organic
Butter … safe Fish oil. Flax has been scientifically proven
to causes prostate cancer cells to grow, and to be a poisonous plant since 1850. It is listed along
with Soy and Canola in the
- 25 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy Isoflavone -
PubMed Abstracts
... Short List ...
NCBI … http://www.ncbi.nlm.nih.gov/pubmed/
See ... Page 74.
1. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9731492&dopt=Abstract
.
1998 “Estrogenic
effects of genistein on the growth of estrogen receptor-positive human breast
cancer (MCF-7) cells in vitro and in vivo,” – Hsieh C.Y., Santell R.C., Haslam S.Z., Helferich W.G.,
Cancer Res 1998 Sep 1 58:17 3833-8.
“... Genistein causes ... the proliferation of cultured human
breast cancer cells ...”
Page 49.
2001 “Dietary
genistin stimulates growth of estrogen-dependent breast cancer tumors similar
to that observed with genistein,” – Allred
C.D. and others, Carcinogenesis
2001 Oct;22(10):1667-73.
Stimulates estrogen-dependent breast cancer cell growth ...
removal of genistein from diet caused tumors to regress ... Genistin is
converted to genistein by human saliva.
Page 42.
1999 “Infantile
leukemia and soybeans–a hypothesis,” – Abe
T., Leukemia
1999 Mar;13(3)317-20.
DNA strand breaks ... Infantile Acute
Leukemia (IAL) .
Page 44.
2000 “Genistein
induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer
cells,” – Salti G.I. and others, Eur J Cancer 2000 Apr;36(6):796-802.
DNA breakage in colon cancer cells occurred
within 1 hour of treatment with genistein.
Page 40.
5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9848512&dopt=Abstract
.
1998 “Effects
of soy-protein supplementation on epithelial proliferation in the
histologically normal human breast,” – McMichael-Phillips
D.F. and others, Am
J Clin Nutr 1998 Dec;68(6 Suppl):1431S-1435S.
The proliferation rate of breast lobular epithelium significantly increased after
just 14 days of soy supplementation ...thus short-term dietary soy containing isoflavone
levels found in modern soy foods stimulates breast proliferation.
Page 47.
2001 “Physiological
concentrations of dietary genistein dose-dependently stimulate growth of
estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude
mice,” – Ju Y.H. and others,
J Nutr 2001
Nov;131(11):2957-62.
Genistein
stimulated
breast tumor growth and cell proliferation in mice in a dose-responsive manner.
Page 50.
2001 “Cross-species
and interassay comparisons of phytoestrogen actions,” – Whitten P.L. and Patisaul H.B.,
Environ Health Perspect 2001
Mar;109 Suppl 1:5-20.
“In vivo data show that
phytoestrogens have a wide range of biologic effects at doses and plasma
concentrations seen with normal human diets.
Significant in vivo responses have been observed in
animal & human tests for ... bone ... breast ... ovary ... pituitary
... vasculature ... prostate and serum lipids. . . . Steroidogenesis and
the hypothalamic-pituitary-gonadal axis appear to be important loci of
phytoestrogen actions,
but these inferences must be tentative because good dose-response data are not
available for many end points.”
Page 90.
8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3559747&dopt=Abstract
.
1987 “Absorption
of zinc from soy protein meals in humans,” – Sandström B., Kivistö B., & others
J Nutr 1987 Feb 117:2 321-7.
Osteoporosis...Lower Zinc absorption...Soy is very
high in Phytic Acid...Soy prevents the absorption of essential minerals
... / 26
- 26 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy Isoflavone - PubMed Abstracts - Short List
...
continued ...
See ... Page 52.
2002 “Dietary
genistein negates the inhibitory effect of tamoxifen on growth of
estrogen-dependent human breast cancer
(MCF-7) cells implanted in
athymic mice,” – Ju Y.H. and others,
Cancer Res 2002
May 1;62(9):2474-7.
The use of “dietary isoflavone supplements” by postmenopausal
women “with breast cancer” is increasing.
Dietary genistein negated or overwhelmed the inhibitor effect of tamoxifen on MCF-7 tumor growth,
lowered E2 levels in plasma, and increased expression of E-response genes
(e.g., pS2, PR, and cyclin D1) in ovariectomized and athymic mice.
“Therefore, “Caution
Is Warranted” for
postmenopausal women consuming dietary genistein while on TAM therapy for
E-responsive breast cancer.”
Page 52.
2002 ““Something
from “nothing” - - eight weak estrogenic chemicals combined at concentrations
below NOECs produce significant mixture effects,” – Silva E. and others, Environ Sci Technol 2002 Apr;36(8):1751-6.
Xenoestrogens
including genistein were tested in combinations. The results were additive,
producing significant effects when combined at low concentrations.
“Our results highlight the limitations of the traditional focus on the
effects of single agents.
Hazard assessments that ignore the possibility of joint
action of estrogenic chemicals will almost certainly lead to significant
underestimations of risk.”
Page 49.
2001 “Soy
diets containing varying amounts of genistein stimulate growth of
estrogen-dependent (MCF-7) tumors in a dose-dependent manner,” – Allred C.D. and others,
Cancer Res 2001
Jul 1;61(13):5045-50.
Depending on processing, soy
protein isolates, SPI’s, very widely in concentrations of genistein.
Soy protein
isolates containing increasing concentrations of genistein stimulate the growth of “estrogen-dependent breast
cancer cells” in vivo in a dose-dependent manner.
Page 52.
2002 “Goitrogenic
and estrogenic activity of soy isoflavones,” – Doerge D.R. and D.M. Sheehan, Environ Health Perspect 2002
Jun;110 suppl 3:349-53.
Although safety testing of natural products, including soy
products, is not required,
the possibility that widely consumed Soy products may cause harm
in the human population via either or both estrogenic and goitrogenic
activities is of concern.
Page 55.
2002“ A
pilot study of the effects of phytoestrogen supplementation on postmenopausal
endometrium,” – Balk J.L. and others,
J Soc Gynecol Investig 2002
Jul-Aug;9(4)238-42.
This was a ... double-blinded ... randomized ...
placebo-controlled trial ... comparing the effects of 6 months of dietary phytoestrogen
supplementation versus placebo in postmenopusal women.
“Phytoestrogens did not cause stimulation of the endometrium.
Insomnia was more frequent over the 6-month study in the soy group, whereas
- hot flushes, night sweats and vaginal dryness improved from baseline in the placebo
group but not in the soy group.”
Page 32.
14. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2548712&dopt=Abstract
.
1989 “Inhibitory
effects of the tyrosine kinase inhibitor genistein on mammalian DNA
topoisomerase II,” – Markovits J. and
others, Cancer
Res 1989 Sep 15;49(18):5111-7.
Genistein stimulates double
strand DNA
breaks.
... / 27
- 27 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy Isoflavone - PubMed Abstracts - Short List
...
continued ...
See ... Page 32.
15. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3297906&dopt=Abstract
.
1987
“Dietary estrogens - a
probable cause of infertility and liver disease in captive cheetahs,” – Setchell K.D. and others, Gastroenterology,
1987 Aug;93(2):
225-233.
Captive adult cheetahs
consuming approximately 50 mg soy isoflavones per day from soy-based feed
develop reproductive failure and liver disease.
When chicken-based feed was substituted for soy-based feed, liver
function improved. “. . .
the relatively high concentrations of phytoestrogens from soybean protein
present in the commercial diet fed to captive cheetahs in
North American zoos may be one of the major factors in the decline of fertility
and in the etiology of - liver disease - in this species.
The survival of the captive cheetah population could depend upon a
simple change of diet by excluding exogenous estrogen.”
Page 31.
1978 “Phytoestrogen
interaction with estrogen receptors in human breast cancer cells,” – Martin M.P. and others, Endocrinology 1978
Nov;103(5):1860-7.
Phytoestrogens “translocate
the cytoplasmic estrogen receptor & bind to unfilled nuclear estrogen
receptors in whole cells. Bound nuclear receptors are then processed in a
manner similar to estradiol in a step which rabidly decreases total cellular estrogen
receptors. Phytoestrogens are also biologically
active; they can markedly enhance tumor cell proliferation.”
“Frying The Brain With Soy”
;
Page 64.
2000 “Brain
aging and midlife tofu consumption, – White
L.R., Petrovitch H., Ross G.W., and others, J Am Coll Nutr. 2000 Apr;19(2):242-55.,
RESULTS: Poor cognitive test performance... enlargement of ventricles... low
brain weight... were each
significantly & independently associated with higher mid-life tofu consumption.
Statistically significant
associations were consistently demonstrated in linear & logistic multivariate
regression models.
CONCLUSIONS: In this population, higher midlife tofu consumption was
independently associated with I hope you and your family find it interesting
and useful ... indicators of cognitive impairment and brain atrophy in late life.
Page 63.
2003 “Soya
phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male
rats,” – File SE, Hartley DE, Alom N., Neurosci Lett 2003 Feb 27;338(2):135-38.,
... Significant reductions were found in brain-derived neurotrophic
factor (BDNF) mRNA expression in the CA3 and CA4 region of
the hippocampus and in the cerebral cortex in
the rats fed the diet containing phytoestrogens,
compared with those on the soya-free diet.
Page 63.
19. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9387865&dopt=Abstract
.
1997 “Brain-derived
neurotrophic factor is reduced in Alzheimer's disease,” – Connor B, Young D, Yan Q, and others., Brain Res Mol Brain Res., 1997 Oct3;49(1-2):71-81.,
... BDNF mRNA is reduced in the human Alzheimer's disease
hippocampus and temporal cortex, and suggest that a loss of BDNF may contribute to the
progressive atrophy of neurons in Alzheimer's
disease.
... / 28
- 28 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy Isoflavone - PubMed Abstracts - Short List
...
continued ...
See ... Page 43.
1999 “Hot
flushes and other menopausal symptoms in relation to soy product intake in
Japanese women,” – Nagata C. and
others, Climacteric
1999 Mar;2(1):6-12.
Intake of fermented soy
products was found to reduce the severity of hot flashes in Japanese women, but
not total soy intake (from unfermented soy products such as are found in
western diets).
This
study is included because it contradicts assertions that Japanese women do
not suffer from hot flashes.
Side
note: All
the promotions for soy for menopausal relief were because Japanese women do not
have a word
for it. All that means is they don't
talk about them. They
have them all right. Look at this research.
Only fermented soy products
had a minor effect and that was just with in the margin of statistical error
(ie.) it was more likely to be random chance !.
Page 56.
2003 “Effect
of soy-derived isoflavones on hot flushes, endometrial thickness, and the
pulsatility index of the uterine and cerebral arteries,” – Penotti M., Fabio E., and others, Fertil Steril 2003 May;79(5):1112-1117.,
To determine the effect of soy-derived isoflavones on hot flushes,
endometrial thickness, and the vascular reactivity of uterine and cerebral
arteries. Double-blind, randomized, placebo-controlled
trial. Healthy volunteers in an academic research
environment.
Daily administration of 72 mg of soy-derived isoflavones is no
more effective than placebo in reducing hot flushes in postmenopausal women.
It also has no effect on endometrial thickness or PI of the uterine and
cerebral arteries
Page 58.
2003 “Cell-transforming
activity and mutagenicity of 5 phytoestrogens in cultured mammalian cells,” – Tsutsui T, Tamura Y, Yagi E, and others, Int J Cancer 2003 Jun 20;105(3):312-20.,
For the simultaneous
assessment of in vitro carcinogenicity and mutagenicity of
phytoestrogens, the
abilities of 5 phytoestrogens, daidzein,
genistein, biochanin A,
prunetin, and coumestrol, to induce cell transformation and genetic effects
were examined using the Syrian hamster embryo (SHE) cell model.
Our results provide evidence that... genistein...
coumestrol... daidzein ... biochanin A ... induce cell transformation in SHE cells
and that the transforming activities of these phytoestrogens correspond to at
least 2 of the mutagenic effects by each phytoestrogen, i.e., gene mutations,
chromosome aberrations, aneuploidy or DNA adduct formation, suggesting possible
involvement of mutagenicity in initiation of phytoestrogen-induced
carcinogenesis.
Page 37.
23. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8896889&dopt=Abstract
.
1996 “Stimulatory
influence of soy protein isolate on breast secretion in pre-and postmenopausal
women,” – Petrakis N.L. and others, Cancer Epidemiol Biomarkers Prev 1996
Oct;5(10):785-794.
The authors noted that “the findings “did
not” support our a priori hypothesis” that soy
protected Asian women against breast cancer.
“Instead, this pilot study indicates that “prolonged
consumption” of soy protein isolate has a “stimulatory effect“ on
the premenopausal female breast ... These findings are suggestive
of an estrogenic stimulus from the isoflavones “genistein”
and “daidzein” contained in soy protein isolate.
Page 42.
1999
“Maternal exposure to
genistein during pregnancy increases carcinogen-induced mammary tumorigenesis
in female rat offspring,” – Hilakiviv-Clarke
L., others, Oncol
Rep 1999 Sep-Oct;6(5):1089-95.
Increased breast tumor risk from foetal exposure to Soy
... Carcinogen-induced mamary tumorigenesis.
... / 29
- 29 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
April
2006
“Hidden Harm”
The Evidence ... Long Known, Ignored, and still Denied
.
(120 + 85(+)
Extra) Short Summaries of Abstracts
and plus
Toxic, Poisonous “Plant Sterols”
from
Isoflavone
Studies
1907 - 1953 – 2004
(+)Plus “The Precautionary
Principle”
Error on the side
of caution … The obligation to prevent harm
Please note: the i does not
indicate any magnitude of importance scientifically, it only indicates order of
importance to me, Gerald Hernesmaa, healthwise933@shaw.ca .
1907 ( See page 83 of this paper) for this abstract from the list in US
FDA’s “Poisonous Plant Database”. For a lot more abstracts between 1907 and
2004 not listed here, click on ….http://www.cfsan.fda.gov/~djw/pltx.cgi?QUERY=soy
, ( see item # 165 ).
1925 "Experimental
rickets: The effect of cereals and their interaction with other factors of diet
and environment in producing rickets", — Mellanby, Edward., Journal of the Medical Research Council 93:265, March 1925, This research footnote
(#20) is from the essay, “The Newest Research On Why You Should
Avoid Soy,” — Fallon S., Enig M.G.,
April 2000, Weston
A. Price Foundation
1953 “Estrogenic
Activity of Isoflavone Derivatives Extracted and Prepared from Soybean Meal,” –
Cheng C. and others, Science 1953;118:164-5.
Feeding 2.5 or 5.0 mg of
either genistein or genistin per day to the mouse resulted in increased uterine
weights.
1954 “Effect of
Genistin on Reproduction of the Mouse,” – Carter
and others, J
Nutr 1954;55:639.
— Exposure to the
phytoestrogen genistin caused significant advancement of the vaginal opening
and a decrease in the number of litters born.
i i i
1956 “Effect of
Genistin on Growth and Development of the Male Mouse,” – Matrone G. and others, J Nutr, 1956, 235-240.
— “The evidence presented
indicates that genistin at certain dose levels has a detrimental effect on
survival, growth rates and spermatogenesis in mice. . . the
higher dose appeared to be lethal. It appears that genistin in relation to its estrogenic activity
has a greater depressing effect on growth than does stilbestrol.”
1963 “Biological
Responses of Young Rats Fed Diets Contain Genistin or Genistein,” – Magee A.C.,
J Nutr 1963;80:151.
— A dietary level of 0.5%
genistin or genistein resulted in significant decreases in weight gain and in
the weights of kidneys and spleen. ... / 30
- 30 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=PubMed
.
1963 “Estrogenic
Effects of Genistein and Coumestrol Diacetate,” – Noteboom and Gorski, Endocrinology, 1963 Dec., 73736-9. No abstract available.
— “It is quite likely that
plant estrogens perform the same function as estradial in triggering anabolic
responses. The results of these
experiments indicate that certain of the nonsteroidal estrogenic compounds are
capable of stimulation of labelled precursors into protein, lipid and
ribonucleic acid in the cells of the rat uterus.”
i i i
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=PubMed
.
1966 “The
interaction in the Immature Mouse of Potent Estrogens with Coumestrol,
Genistein and other utero-Vaginotropic Compounds of Low Potency,” – Folmon Y. and others, J Endrocrin 1966 ;34:215-225. No abstract available.
— Phytoestrogens such as
genistein are said to be of “weak” potency. This study found that sometimes
these estrogens were additive at very small doses and appeared to be
antagonistic at higher doses. “Genistein gave a steep dose-response curve with
high responses (uterus weight near 45 grams) typical of the most potent
estrogens.”
i i i , i i i , i - can cause reproductive
disorders in females.
1967 “The
oestrogenic activity and metabolism of certain isoflavones in sheep,” – Braden and others, Australian Journal of Agricultural Research
1967, 18:335-348.
— “Some plants that are
commonly grazed nevertheless contain substances that are harmful to the animals
ingesting them and one group of such compounds (phyto-estrogens) can
cause reproductive disorders in females.”
1972 “Steroid and
Phytoestrogen Binding to Sheep Uterine Receptors in Vitro,” – Shutt D.R., J Endocrin 1972;52:299-305.
— Phytoestrogens were found to
compete with estradiol for binding sites. “A full estrogenic response is elicited
only when they are given in repeated frequent doses, which may be necessary to
maintain a high blood concentration.”
i i i , i i i , i
1976 “Phytoestrogens:
Adverse effects on reproduction in California Quail,” – Leopold A.S. and others, Science, 1976
Jan 9;191(4222): 98-100.
— During dry years,
phytoestrogens, including genistein, are produced in the leaves of stunted
desert annuals. When ingested by California quail, these compounds apparently inhibit
reproduction and prevent the
production of young
that will not have adequate food. In a wet year, forage grows vigorously and
phytoestrogenic substances are largely absent. Quail then breed prolifically
and the abundant seed crop carries the enlarged population through the winter.
i i i , i i i , i i i , i i i - developed
enlarged goiters and malignant thyroid tumors.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1035180&dopt=Abstract
.
1976 “Development of
malignant goiter by defatted soybean with iodine-free diet in rats,” – Kimura S. and others, Gann 1976,
67:763-765.
— Iodine-deficient rats fed
defatted soybean for 6 to 12 months developed enlarged goiters and malignant
thyroid tumors. Thyroid enlargement was inhibited with the
addition of small amounts of iodine to the diet.
... / 31
- 31 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i - reduce fertility
1976 “The Effects of
Plant Estrogens in Animal Reproduction,” – Shutt
D.R., Endeavour 1976:110-113.
— “In high concentrations, a
weak plant estrogen can exert a significant estrogenic effect in the animal and
can product hormonal imbalance ... when high blood concentrations are
maintained, they can exert a maximal estrogenic effect ... From the wider
viewpoint of evolution, it is interesting that compounds have evolved in plants
that not only give the plant some protection from pathogens, but also reduce
fertility of animals ingesting the plant.”
i i i , i i i , i - fertility impairment
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1066275&dopt=Abstract
.
1976 “Occurrence of
Anabolic Agents in Plants and their Importance,” – Lindner H.R., Environment Quality Supplement 1976;5:151-158.
— “Coumestrol and genistein
stimulate estradiol in stimulating macromolecular changes in the uterus. The
biological effects of clover estrogens responsible for fertility
impairment appear to be
multiple.”
i i i , i i i , i i i , i i i - Phytoestrogens can
markedly enhance tumor cell proliferation
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=570914&dopt=Abstract
.
1978 “Phytoestrogen
interaction with estrogen receptors in human breast cancer cells,” – Martin M.P. and others, Endocrinology 1978
Nov;103(5):1860-7.
— Phytoestrogens can markedly
enhance tumor cell proliferation. The interactions of phytoestrogens with
estrogen receptors were studied in the human breast cancer cell line, MCF-7.
— The compounds tested were ...
coumestrol ... genistein ... and
formononetin and the mycotoxins, zearalenone and its reduced derivative,
zearalenol. All but formononetin compete for binding of [3H]-estradiol
to unfilled cytoplasmic estrogen receptor or unfilled nuclear estrogen receptor
sites.
— The phytoestrogens are also
biologically active; they
can markedly enhance tumor
cell proliferation.
— In summary ... phytoestrogens interact with the estrogen
receptors of human breast cancer cells in culture and, therefore, may affect estrogen-mediated events in
these cells.
— Phytoestrogens “translocate
the cytoplasmic estrogen receptor and bind to unfilled nuclear estrogen
receptors in whole cells. Bound nuclear receptors are then processed in a
manner similar to estradiol in a step which rabidly decreases total cellular estrogen
receptors. The phytoestrogens are also biologically
active; they can markedly enhance tumor cell proliferation.”
1980 “Oestrogenic
activity of soya-bean products,” – Drane
H. M. and others,
Food Cosmetics and Technology 1980
Aug ;18(4): 425-427.
— Sixteen samples of
soya-containing products were examined after the commercial mouse diet was
found to have estrogenic effects in laboratory mice, and compared with the
effects of DES on the weight of the mouse uterus. All samples demonstrated
estrogenic activity. The researchers attributed the effects as equivalent to 16
ppm and 24 ppm DES in the two samples of human food used.
i i i , i i i , i i i , i i i - has been know for more
than half a century
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4018320&dopt=Abstract
.
1985 “Naturally
Occurring Estrogens in Food - - A Review,” – Jones and others, Journal of Food Additives and Contamination 1985;2(2):73-106.
; i ; — That estrogen compounds in plants “induce estrus in immature
animals and interfere with normal reproductive processes has
been know for more than half a century. Consideration should be taken of any medium or long-term changes
in dietary habits which might be expected to increase the intake of such
phytoestrogens. The increasing use of vegetable proteins in general and in
particular and the introduction of soy milk products for
infant feeding are two
such examples.”
... / 32
- 32 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i
1985 “Non Steroidal
Estrogens of Dietary Origin,” – Setchell
K.D., Estrogens
in the Environment, John A McLaughlin, ed. Elsivir, 1985:69-83.
— “Since as little as 8 mg of
genistein and 10 mg of daidzein are sufficient to initiate uterotrophic effects
in mice, it is not surprising that the relatively large amounts of isoflavones
present in soy protein will readily explain the previously observed estrogenic
effects in animals ... The effects of plant estrogens in man should, however, be
of some concern since the newborn infant will be subject to chronic
exposure to soya–milk, in some cases for up to two years ... this situation could be
considered analogous to sheep grazing on clover.”
i i i
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2980380&dopt=Abstract
.
1987 “Effects of
phytoestrogens on GnRH-induced luteinizing hormone secretion in ovariectomized
rats,” – Hughes C.I. Jr.,
Reprod Toxicol 1987-88;1(3):179-81.
— “The dose potency of
genistein appears to be approximately 1/10 that of E2 [estradiol-17 beta] in
this system. Phytoestrogens acutely perturb reproductive neuroendocrine
function.”
i i i , i i i , i i i , i i i - liver function improved
…
…
when chicken-based feed was substituted for soy-based feed.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3297906&dopt=Abstract
.
1987 “Dietary
estrogens - a probable cause of infertility and liver disease in captive
cheetahs,” – Setchell K.D. and others,
Gastroenterology Aug;1993(2): 225-233.
— Captive adult cheetahs
consuming approximately 50 mg soy isoflavones per day from soy-based feed
develop reproductive failure and liver disease.
— When chicken-based feed was substituted for soy-based
feed, liver function improved. “. . . the relatively high concentrations of phytoestrogens from
soybean protein present in the commercial diet fed to captive cheetahs in
North American zoos may be one of the major factors in the decline of fertility
and in the etiology of - liver disease - in this species.
The survival of the captive cheetah population could depend upon a
simple change of diet by excluding exogenous estrogen.”
i i i , i i i , i i i , i i i - double strand DNA
breaks.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2548712&dopt=Abstract
.
1989 “Inhibitory
effects of the tyrosine kinase inhibitor genistein on mammalian DNA
topoisomerase II,” – Markovits J. and
others, Cancer
Res 1989 Sep 15;49(18):5111-7., Laboratorie
de Pharmacologie Moleculair, URA 158 du CNRS, U 140 de I’NSERM, Institute
Gustave Roussy,
; i ; — Genistein stimulates double strand DNA
breaks.
— Our results show that genistein (a) inhibits the decatenation
activity of DNA topoisomerase II and (b) stimulates
DNA topoisomerase II-mediated double strand breaks in pBR322 DNA
on sites different from those of
4'-(9-acridinylamino)methanesulfon-m-anisidide, etoposide, and
2-methyl-9-hydroxyellipticinium.
— Finally, genistein treatment of DC-3F cells results in the occurrence of protein-linked
DNA strand breaks as
shown by DNA filter elution. Viscometric (lengthening) studies demonstrate that
genistein isn’t a DNA intercalator. Genistein is therefore an interesting
compound because it induces cleavable complexes without intercalation.
— Taken together, our results show that genistein is an inhibitor of
both protein tyrosine kinases and mammalian DNA topoisomerase II. This could be
accounted for by the sharing of a common structure sequence between the two
proteins at the ATP binding site.
... /
33
- 33 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i
1989 “Development
and Application of High Performance Chromatographic Method for the Analysis of
Phytoestrogens,” – Jones A.E., Jour
Sci Food Agric 1989;46:157-164.
— “It should be emphasized
that the effects of long-term low level exposure are unknown ... Vegetarians,
vegans and those relying
on ‘health’ food preparations from alfalfa, legumes or soya in particular would appear to be likely
to regularly consume very much higher levels of
estrogens than those
estimated for the population at large.
i i i , i i i , i i i , i i i - DNA cleavage in vitro.
1990 “Induction of
mammalian topisomerase II dependent DNA cleavage by nonintercalative
flavonoids, genistein and orobol,” – Yamashita
Y. and others, Biochem
Pharmacol 1990 Feb 15;39(4):737-44.
— Genistein induced DNA cleavage in vitro.
i i i , i i i , i
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1868922&dopt=Abstract
.
1991 “The effects on
the thyroid gland of soybeans administered experimentally in healthy subjects,”
– Y. Ishizuki and others, Nippon
Naibunpi Gakkai Zasshi 1991, 767: 622-629.
— Feeding 30 grams (2
tablespoons) soybeans per day for three months to healthy adults receiving
adequate iodine intake caused thyroid suppression, especially in the elderly.
Hypometabolic symptoms (malaise, constipation, sleepiness) and goiters appeared
in half the younger subjects (mean age of 29) and half the older subjects (mean
age 61). The symptoms disappeared 1 month after the cessation of soybean
ingestion. “These findings suggested that excessive
soybean ingestion for a certain duration might suppress thyroid function and
cause goiters in healthy people, especially elderly subjects.” Note that 30 grams per day was considered
“excessive” by these Japanese researchers.
1991 “Estrogenic
effect of dietary soy bean meal on vitellogenesis in cultured Siberian Sturgeon
Acipenser baeri,” – Pelissero C. and
others, Gen
Comp Endocrinol 1991 Sep;83(3):447-57 83:447-457.
— Sturgeon fed a diet high in
isoflavones from soybeans had significantly higher levels of plasma
vitellogenin. Vitellogenin
is a biomarker for estrogenic effects.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1656271&dopt=Abstract
.
1991 “Long-term
potentiation in the hippocampus is blocked by tyrosine kinase inhibitors,” – O’Dell T.J. and others,
Nature 1991
Oct;353(6344):558-60.
— Long-term potentiation (LTP)
in the hippocampus is thought to contribute to memory formation. Tyrosine kinase
inhibitors (such as genistein) block LTP.
i i i , i i i , i i i , i i i - a strong
immuno-suppressant
1991 “Evidence that
genistein, a protein-tyrosine kinase inhibitor, inhibits CD28
monoclonal-antibody-stimulated human T cell proliferation,” – Atluru S. and Atluru D.,
Transplantation 1991
Feb;51(2):448-50., Department of Anatomy and Physiology,
; i ; —
Genistein blocks the production of T cells, needed for the immune
system.
— The authors conclude: “ ... that genistein is a powerful
immuno-suppressive agent ...” and suggest that it has a potential use in
the treatment of allograft rejection.
... / 34
- 34 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - 100 grams of Soy protein
= 1 contraceptive pill
-
http://www.mercola.com/article/soy/avoid_soy.htm
, Foot Note #53.
1992 “Bulletin de L’Office Federal de la Santé
Publique,” — #53. Bulletin de L'Office
Fédéral de la Santé Publique, No. 28,
— The Swiss Health Service estimates that 100
grams of soy protein provides the estrogenic equivalent of the contraceptive
pill.
i i i , i i i , i i i , i i i - a strong
immuno-suppressant
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1330289&dopt=Abstract
.
1992 “Effects of
genistein on the growth and cell cycle progression of normal human lymphocytes
and human leukemic MOLT-4 and HL-60 cells,” – Traganos F. & others, Cancer Res 1992 Nov 15;52(22):6200-8., Cancer
Research Institute, New York Medical College, Valhalla 10595.
; i ; — The results suggest that genistein
“is expected to be a strong immuno-suppressant.
— Genistein (GEN) is an isoflavone known to inhibit both
tyrosine protein kinases and DNA topoisomerase II.
— The effects of GEN on cell proliferation and cell cycle kinetics
of human myelogenous leukemia
HL-60 and lymphocytic leukemia MOLT-4 cell cultures were
studied, and the data were compared to results obtained with normal human
lymphocytes stimulated to proliferate with phytohemagglutinin.
i i i , i i i - in all kinds of farm
animals ... risk to man cannot be excluded.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1387742&dopt=Abstract
.
1992 “Validation of
Two In Vitro Test Systems of Estrogenic Activities with Zearelenone
Phytoestrogens and Cereal Extracts,” – Mayr
U., Toxicology
1992;72:135-149., Institut
fur Tierernahrung, Universitat Hohenheim, Stuttgart, Germany.
— disease ... in all kinds of farm animals ... inherent health risk
... to man cannot be excluded.
— “Ingestion of these compounds causes diseases of the ...
reproductive system ... reversible and irreversible infertility ... and
abnormal fetal development ... in all kinds of farm animals.
— Furthermore, an inherent health risk to
man cannot be excluded.” This paper contains graphs showing the
crossover of phytoestrogens from estrogenic to antiestrogenic to toxic.
i i i , i i i , i i i , i i i - http://www.soyonlineservice.co.nz/04immunefunction.htm .
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8393675&dopt=Abstract
1993 “Genistein
induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II,”
– McCabe M.J. Jr. and Orrenius S., Biochem Biophys Res Commun 1993; 194(2):944-50.
— The toxicity of genistein on
human thymus cells was investigated. “Genistein induced marked chromatin fragmentation indicative of apoptosis
in human thymocyte cultures.”
i i i , i i i , i i i , i i i - Errors in chromosome orientation -
- http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8314908&dopt=Abstract
.
1993 “Odd chromosome
movement and inaccurate chromosome distribution in mitosis and meiosis after
treatment with protein kinase inhibitors,” – Nicklas R.B. and others, J Cell Sci 1993 Apr;104 part 4:961-73.,
Department of Zoology, Duke University, Durham, NC 27706.
; i ; — Genistein, a
protein kinase inhibitor, caused errors
in chromosome orientation from grasshopper spermatocytes.
... /
35
- 35 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i
1994 “Biological
Effects of a Diet of Soy Protein Rich in
Isoflavones on the Menstrual Cycle of Premenopausal Women,” – Cassidy A. and others, Am J
Clin Nutr 1994 Sep;60(3):333-340.
— Six women with regular
menstrual cycles were given 60 grams soy protein containing 45 mg isoflavones
daily. After one month, all experienced delayed menstruation. Luteinizing
hormone and follicle-stimulating hormone were significantly suppressed. The
effects were similar to those of tamoxifen, an antiestrogen drug. Regular menstruation did not resume until 3
months following the cessation of soy protein consumption.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7507447&dopt=Abstract
.
1994 “The ligand of
the c-kit receptor promotes oocyte growth,” – Packer A.I. and others, Dev Biol 1994 Jan;161(1):194-205.
— “In the presence of genistein, many of the follicles became
disorganized and the oocytes became partially denuded (Fig. 6B). There also
appeared to be less granulosa cell proliferation compared to the control
follicles.” This statement appeared in
the body of the report, not in the abstract.
i i i i
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8147890&dopt=Abstract
.
1994 “Hepatocyte
Growth Factor Accelerates the Wound Repair of Cultured Gastric Mucosal Cells,”
– Watanabe S. and others,
Biochem Biophys Res Comm 1994;
199(3) 1453-60.
— Genistein retarded the
repair of gastric mucosal cells, suggesting that genistein may retard the
healing of gastric ulcers.
1994 “Nonsteroidal
estrogens of dietary origin: possible roles in hormone-dependent disease,” – Setchell K.D. and others,
Am J Clin Nutr 1984 Sep;40:569-78.
— Equol is a breakdown product
of phytoestrogens which shows up in the urine of individuals who eat soy.
However, some subjects are unable to breakdown phytoestrogens and equol
does not show up in their urine.
i i i , i i i , i i i , i i i - children exposed to
estrogens ... more susceptible to prostate
cancer later in life
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7508622&dopt=Abstract
.
1994 “Developmental
estrogenization and prostatic neoplasia,” – Santti
R. and others, Prostate
1994; 24(2):67-78., Department
of Anatomy,
; i ; — Children exposed to Estrogens ... more
susceptible to prostate cancer later in life
— The association of estrogens with benign prostatic
hyperplasia and prostatic cancer has been widely studied, but no conclusive
evidence exists for a role of estrogens in prostatic disease. This
paper reviews the literature and describes studies which have sought to show a
correlation of estrogens and alterations in the prostates of humans and
experimental animal models.
— Using the developmentally estrogenized mouse model, we propose an
alternative role for estrogens as a predisposing factor for prostatic diseases:
estrogen exposure during development may initiate cellular changes in the
prostate which would require estrogens and/or androgens later in life for promotion to hyperplasia or neoplasia.
— Evidence indicates ...
that estrogen exposure during development may initiate cellular changes in the
prostate which would require estrogens and/or androgens later in life for
promotion of prostatic hyperplasia or neoplasia.
— Thus, the critical time for
estrogen action would be during the development of the prostatic tissue.
— We further suggest that estrogen-sensitive cells may
remain in the prostate and be more responsive to estrogens later in life
or less responsive to the normal controlling mechanisms of prostatic growth.
— In other words, exposure of the developing male child to phytoestrogens in soy may
make him more susceptible to prostate cancer later in life.
... / 36
- 36 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7488041&dopt=Abstract
.
1995 “Dietary
estrogenic isoflavones are potent inhibitors of B-heydroxysteroid dehydrogenase
of P testosteronii,” – Keung W.M.,
Biochem Biophys Res Commun 1995
Oct 24;215(3):1137-1144.
— The isoflavones daidzein,
genistein, biochanin A and formononetin were found to inhibit
enzymes that produce steroid hormones critical to reproductive and
neurological function, particularly hormones that produce testosterone.
i i i
1995 “Dietary
soybean may be antiestrogenic in male mice,” – Makela S.I. and others, J Nutr 1995 Mar;125(3):437-45.
— Soy isoflavones were found to have antiestrogenic action in male
mice.
i i i , i i i , i i i , i i i , i - causing DEATH ... ; i ;
1995 “Phytoestrogens
and parrots: The anatomy of an investigation,” – Woodhams D.J., Proceedings of the Nutrition Society of New Zealand. 1995,
; i ; —
Observations in aviaries and in handrearing of parrots
with bird-baby food were associated with parrot infertility, premature sexual
maturation and in some cases acute symptoms causing DEATH. It was
noted that soy protein and/or soy meal were a
constant ingredient in all the diets used.
; i ; — This
triggered an investigation into the literature on the toxic effects of
processed soy products.
The first source consulted was Soy
Beans: Chemistry and Technology by Smith and Circle, an industry test book published in 1972 that clearly listed a number of
established toxic effects, with copius reference lists for each chapter.
i i i , i i i , i i i , i i i -
1995 “The Potential
Adverse Effects of Soybean Phytoestrogens in Infant Feeding,” –
— “Exposure to estrogenic
compounds may pose developmental hazard in infants...particularly to
reproductive system ... Neonates are generally more susceptible than adults to
perturbations of the sex steroid milieu.
i i i , i i i , i i i , i i i - Soy has
glycosides of genistein and daidzein or plant based chemicals
that
mimic
estrogen
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9217716&dopt=Abstract
.
1997 “Exposure of
infants to phyto-oestrogens from soy-based infant formula,” – Setchell K.D., Zimmer-Nechemias L., Cai J.,
Heubi J.E.,
Lancet. 1997 Jul 5;350(9070):23-7.,
— INTERPRETATION:. Soy
has glycosides of genistein
and daidzein ... or plant based chemicals that mimic
estrogen.
; i ; —
The daily exposure of infants to
isoflavones in soy infant-formulas is 6-11 fold higher
on a body-weight basis than the dose that has hormonal effects in adults
consuming soy foods.
Circulating concentrations of isoflavones in the seven infants fed soy-based
formula were 13000-22000 times higher than plasma oestradiol concentrations in
early life, and may be sufficient to exert biological effects, whereas the contribution of isoflavones from breast-milk and
cow-milk is negligible.
... / 37
- 37 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i
1995 “Phytoestrogens:
Toxicology and Regulatory Recommendations,” – Robertson I.G.C., Proc Nutr Soc of NZ 1995;
— “Concerns have been
expressed about possible adverse effects, particularly to the foetal-neonatal
nervous and reproductive system. Adverse effects may occur by inhibition of the
enzyme which converts the relatively impotent estrone to the much more potent
oestradiol and by occupying the estrogen receptor resulting in antagonism of
the naturally produced oestradiol. Adequate oestradiol is necessary for the
imprinting and development of many physical, physiological and behavioural characteristics during the
neonatal period and infancy. Infants on soy-based formula have been identified
as a high risk group because the formula is the main source of nutrient, and
because of their small size and developmental phase. Infants
absorb phytoestrogens and have a calculated daily dietary intake (per kg) 3-6
times that shown to have physiological effects on women ...”
i i i , i i i , i i i , i i i , i - The authors noted that
“the findings did not support our a priori
hypothesis” that
soy protected Asian women against breast cancer.
“Instead, this
pilot study indicates that “prolonged consumption” of soy protein
isolate has a “stimulatory
effect” on the premenopausal female
breast ... genistein
and daidzein in Soy protein isolate (SPI).
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8896889&dopt=Abstract
.
1996 “Stimulatory
influence of soy protein isolate on breast secretion in pre-and postmenopausal
women,” – Petrakis N.L. and others, Cancer Epidemiol Biomarkers Prev 1996
Oct;5(10):785-794., Department
of Epidemiology and Biostatistics,
— Twenty-four (24) normal pre-
and postmenopausal white women, ages 30 - 58 were studied for one year. During months 4-9, the women ingested 38 g soy protein isolate containing 38 mg genistein.
Seven of the 24 women developed epithelial hyperplasia during the period
of soy feeding, a condition that presages breast cancer.
— The authors noted that
“the findings did not support our a priori hypothesis” that soy
protected Asian women against breast cancer. “Instead, this
pilot study indicates that prolonged consumption of soy protein isolate has a
stimulatory effect on the premenopausal female breast, characterized by increased
secretion of breast fluid, the appearance of hyperplastic epithelial cells and
elevated levels of plasma estradiol.
— These findings are suggestive
of an estrogenic stimulus from the isoflavones genistein and daidzein
contained in Soy protein isolate (SPI).”
i i i , i i i , i i i , i i i - stimulate human breast
cancer cells to enter the cell cycle ; i ;
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9168007&dopt=Abstract
.
1997 “Dietary
estrogens stimulate human breast cells to enter the cell cycle,” –
; i ; —
Dietary estrogens were found to increase
enzymatic activity leading to breast cancer.
; i ; ---
“Our findings are consistent with a conclusion that dietary estrogens,
(genistein), at low concentrations do not act as antiestrogens, but act
like DDT and estradiol to stimulate
human breast cancer cells , (MC-7), to enter the cell cycle.
; i ; Note: At
the end of this full research paper, Dees concluded that "... women should
not consume particular foods, (eg. Soy
derived products), to prevent breast
cancer ..."…
Also
see Dees C. , on
pages 74 and 73.
i i i , i i i , i i i , i i i - DNA strand breaks …
http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9225019&dopt=Abstract
.
1997 “Induction of
micronuclei, DNA strand breaks and HPRT mutations in cultured Chinese hamster
V79 cells by the phytoestrogen coumoestrol,” – Kulling S.E. and Metzler M., Food Chem Toxicol 1997 Jun;35(6):605-13., Institute of Food Chemistry, University of
Karlsruhe, Germany.
— Coumoestrol and genistein
caused DNA strand breaks in cultured hamster cells.
... / 38
- 38 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - Stimulates
growth of tumors ... Suppress enzymes protective
of breast cancer
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9343831&dopt=Abstract
.
1997 “Phytoestrogen
concentration determines effects on DNA synthesis in human breast cancer
cells,” – Wang C. and Kurzer M.S.,
Nutr Cancer 1997;28(3):236-47., Department
of Food Science and Nutrition,
; i ; —
Soy intake caused larger mammary fat pad tumors to occur in mice. Soy
feeding appeared to suppress enzymes protective of breast cancer.
— Although high levels of
isoflavones inhibited DNA synthesis in human breast cancer cells, low levels of genistein
and related compounds induced DNA synthesis 150-235%. “The current focus on the role of
phytoestrogens in cancer prevention must take into account the biphasic effects
observed in this study, showing inhibition of DNA synthesis at high concentrations but
induction at concentrations close to probable levels in humans.”
— “Óur data suggest the possibility that, at
typical concentrations in humans, phytoestrogens and related flavonoids and
lignans may stimulate, rather than inhibit, growth of estrogen-dependent tumours.”
— Soy intake caused larger
mammary fat pad tumors to occur in mice. Soy feeding appeared to suppress
enzymes protective of breast cancer.
i i i , i i i , i i i , i i i - DNA damage to human
sperm ...
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9249928&dopt=Abstract
.
1997 “Effect of
various genotoxins and reproductive toxins in human lymphocytes and sperm in
the Comet assay,” – Anderson D. and
others, Teratog Carcinog Mutagen 1997;17(1):29-43., Department
of Genetic and Reproductive Toxicology, BIBRA International, Carshalton,
— DNA damage to human sperm ...
— Human sperm exposed to the
phytoestrogen daidzein had reduced DNA integrity.
— “The integrity of DNA is necessary not only for the noncancerous state, but
also for the accurate transmission of genetic material to the next generation.”
i i i , i i i , i i i , i i i (+)
i i i - identifies genistein & daidzein
as goitrogenic compounds in Soy, inhibition
of enzymes involved in the production of thyroid hormones ... in
humans consuming Soy products.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9464451&dopt=Abstract
.
1997 “Anti-thyroid
isoflavones from the soybean: isolation, characterization & mechanisms,” – Divi R.L., Chang H.C. Doerge D.R., and
others, Biochem
Pharmacol 1997 Nov 15; 54:1087-96., National Center for Toxicological Research,
Jefferson, Ar., 72079, USA.
— This important study
identifies the goitrogenic compounds in soy as the isoflavones genistein &
daidzein, which were
found to inhibit synthesis
of thyroid hormone. Inhibition of enzymes involved in the
production of thyroid hormones occurred at isoflavone levels “previously
measured in plasma from humans consuming soy products.”
— The extensive consumption of soy products in infant formulas and
in vegetarian diets makes it essential to define the goitrogenic potential……“Because inhibition of thyroid
hormones synthesis can induce goiter and thyroid neoplasia in rodents, delineation of antithyroid
mechanisms for soy isoflavones may be important for extrapolating goitrogenic
hazards identified in chronic rodent bioassays to humans consuming soy products.....This
mechanism predicts that any compound that
inhibits TPO-mediated thyroid hormone synthesis is a potential thyroid
carcinogen." Authors note: “The soybean has been
implicated in diet-induced goiter by many studies.”
i i i , i i i , i i i , i i i - stimulate
cellular changes leading to breast cancer
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9383784&dopt=Abstract
.
1997 “Effects of
dietary menhaden oil, soy, and a cyclooxygenase inhibitor on human breast
cancer cell growth and metastasis in nude mice,” – Connolly J.M. and others, Nutr Cancer 1997;29(1):48-54., Division of Nutrition and Endocrinology,
American Health Foundation,
; i ; —
Phytoestrogens at levels close to probable levels in humans were found to stimulate
cellular changes leading to breast cancer.
... /
39
- 39 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9288778&dopt=Abstract
.
1997 “Enhancement of
experimental colon cancer by genistein,” – Roa
C.V. and others, Cancer
Res 1997 Sep 1;57(17):3717-22.
— Administration of genistein
to rats caused an increase in colon tumor enhancement.
i i i , i i i , i i i , i i i - risk: benefit
ratio ...
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9492351&dopt=Abstract
.
1998 “Herbal medicines,
phytoestrogens and toxicity: risk: benefit considerations,” – Sheehan D.M., Proc
Soc Exp Biol Med 1998
Mar;217(3):379-85.
— Knowledge of toxicity is
crucial to
decrease the risk:benefit
ratio, but herbal medicines and
phytoestrogens in food are not tested as are drugs.
; i ; —
“Important toxicities with long latencies are particularly difficult to
associate with a causative agent ... These considerations suggest
that much closer study in experimental animals and human populations exposed to
phytoestrogen-containing products, and particularly soy-based foods, is
necessary. Among human
exposures, infant soy formula exposure appears to provide the highest of all
phytoestrogen doses, and this occurs during development, often the most
sensitive life-stage for induction of toxicity.”
i i i
1998 “Dietary
phytoestrogens and their role in hormonally dependent disease,” – Strauss L. and others,
Toxicol Lett 1998
Dec 28;102-103:349-54.,
— Although epidemiological studies
suggest that diets rich in phytoestrogens may be associated with low risk of
breast and prostate cancer, there is no direct evidence for the
beneficial effects of phytoestrogens in humans. It is plausible that phytoestrogens, as
any exogenous hormonally active agent, might also cause adverse effects in the
endocrine system.
i i i , i
1998 “Environmental
signaling: a biological context for endocrine disruption,” – Cheek A.O. and others,
Environ Health Perspect 1998
Feb;106 suppl 1:5-10.
— The authors discuss the
effects of various compounds on steroid-like signaling pathways, especially
estrogen. “Based on their mechanisms of action, chemical steroid mimics could
plausibly be associated with recent adverse health trends in humans and animals.
i i i , i
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9848516&dopt=Abstract
.
1998 “Isoflavone
content of infant formulas and the metabolic fate of these early phytoestrogens
in early life,” – Setchell K.D. and
others, Am
J Clin Nutr 1998 Dec;68(6 Suppl):1453S-1461S.
— Plasma isoflavone levels in
infants fed soy-based formula were 13,000-22,000 higher than concentrations
found in fed breast milk or milk-based formula. These high levels are explained
“by reduced intestinal biotransformation, as evidenced by low or undetectable
concentrations of equol and other metabolites, and is maintained by constant
daily exposure from frequent feeding.” The authors assert that these
unnaturally high levels of isoflavones in the bloodstreams of soy-fed children
“may have long-term health benefits for hormone-dependent diseases.”
...
/ 40
- 40 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - cellular damage and
DEATH, genistein in Soy is a chromosomal
mutagen
-
Soy Online Service …
http://www.soyonlineservice.co.nz/04immunefunction.htm
.
NCBI - PubMed …
http://www.ncbi.nlm.nih.gov/pubmed/
,
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9729267&dopt=Abstract
.
1998 “p53,
mutations, and apoptosis in genistein-exposed human lymphoblastoid cells,” – Morris S.M. and others,
Mutat Res 1998
Aug 31;405(1):41-56. Division
of Genetic and Reproductive Toxicology, National Center for Toxicological
Research, Food and Drug Administration, Jefferson, AR 72079, USA
; i ; —
In vitro administration of genistein was found to cause cellular
damage and DEATH. “Our
results may be interpreted that genistein is a chromosomal mutagen ...”
— The phytoestrogen, genistein, is a naturally occurring isoflavone
found in soy products.
— On a biochemical basis, genistein is a competitive inhibitor of
tyrosine kinases and the DNA synthesis-related enzyme, topoisomerase-II
(topo-II).
— Exposure of mammalian cells to genistein results in DNA damage
that is similar to that induced by the topo-II inhibitor and chromosomal
mutagen, m-amsa.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9460177&dopt=Abstract
.
1998 “Phytoestrogens:
potential endocrine disrupters in males,” – Santti
R. and others, Toxicol
Ind Health 1998 Jan-Apr;14(1-2):223-37.
— In doses comparable to the
daily intake from soy-based feed, isoflavonoids such as genistein were estrogen
agonists in the prostate of adult
laboratory rodents. When given
neonatally, no persistent effects were observed. In contrast, the central nervous system
(CHS)-gonadal axis and the male sexual behavior of the rat appear to be
sensitive to phytoestrogens during development. The changes were similar but
not identical to those seen after neonatal treatment with DES, but higher doses of phytoestrogens were
needed.
i i i , i i i , i i i , i i i - Genistein is a
chromosomal mutagen ... short term dietary use of soy foods
stimulates
breast cancer cell proliferation ... Soy foods stimulate breast proliferation
... after just 14 days
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9848512&dopt=Abstract
.
1998 “Effects of
soy-protein supplementation on epithelial proliferation in the histologically
normal human breast,” – McMichael-Phillips
D.F. and others, Am
J Clin Nutr 1998 Dec;68(6 Suppl):1431S-1435S. Depart.
of Epithelial Biology, Paterson Institute for Cancer Research,
; i ; —This
study examines the effects of dietary soy supplementation on the proliferation
rate of premenopausal, histologically normal breast epithelium and the
expression of progesterone receptor.
— Soy foods stimulates breast proliferation ... after just
14 days
— Forty-eight, 48, women with benign or malignant breast disease
were randomly assigned a normal diet either alone or with a 60 gram soy
supplement containing 45 mg isoflavones, taken for 14 days.
— The proliferation rate of breast lobular epithelium ...
significantly increased ... after just 14 days ... of soy supplementation ...
when both the day of menstrual cycle & age of patient were accounted
for. Thus short-term use of dietary soy
containing isoflavone levels found in
modern soy foods stimulates breast proliferation.
; i ; —
Our results may be interpreted that ... genistein is a chromosomal
mutagen and that p53 functional status affects the recovery of chromosomal
mutants, possibly by signalling cells into the apoptosis pathways. Short-term dietary soy
stimulates breast proliferation; further studies are required to determine
whether this is due to estrogen agonist activity & to examine the long-term
effects of soy supplementation on the pituitary gland / breast
i i i , i i i
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9863629&dopt=Abstract
.
1998 “Genistein
exerts estrogen-like effects in make mouse reproductive tract,” – Strauss
and others, Mol
Cell Endocrinol 1998 Sept 25;144(1-2):83-93.
; i ; — Genistein was found to have estrogenic
effects in adult male mice, at doses comparable to those present
in Soy-based human diets. In neonatal animals, considerably higher
doses are required to show estrogen-like activity.
... / 41
- 41 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i
1999 “Developmental
effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of
genistein and daidzein with rat estrogen receptors alpha and beta in vitro,” – Casanova M. and others,
Toxicol Sci 1999
Oct;51(2):236-44.
— Effects of dietary genistein
included a decreased rate of body-weight gain, a markedly increased (2.3 fold)
uterine/body weight and a significant acceleration of puberty among females.
e
i i i , i i i , i i i , i i i - caused Chromosomal
aberrations, chromatid breaks, gaps, interchanges
1999 “The
phytoestrogens coumoestrol and genistein induce structural chromosomal
aberrations in cultured human peripheral blood lymphocytes,” – Kulling S.E. and others,
Arch Toxicol 1999
Feb;73(1):50-4.,
; i ; —
Phytoestrogens “coumoestrol” & “genistein” caused chromosomal aberrations in human peripheral blood
lymphocytes in vitro. “The major alterations were chromatid breaks,
gaps and interchanges ...
— Exposure of blood
lymphocytes to low levels of genistein in vitro caused chromosomal
aberrations including chromatid breaks, gaps and interchanges.
Exposure to daidzein did not cause aberrations, even at high
levels. The results suggest that “...
some but not all phytoestrogens have the potential for genetic toxicity.”
1999 “Effect of
neonatal exposure to estrogenic compounds on development of the excurrent ducts
of the rat testis through puberty to adulthood,” – Fisher J.S. and others, Environ Health Perspect 1999
May;107(5):397-405.
— Administration of genistein
to rats caused minor but significant changes in rat testes. “This study suggests that structural and
functional.. . development of the excurrent ducts is susceptible to impairment
by neonatal estrogen exposure, probably as a consequence of direct effects. The magnitude and duration of adverse changes
induced by treatment with a range of estrogenic compounds was broadly
comparable to their estrogenic potencies reported from in vitro assays.”
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
- Soy phytoestrogens affect brain function of female rats ... promote
sexual maturation
1999 “Effect of
estradiol and soy phytoestrogens on choline acetyltransferase and nerve growth
factor mRNAs in the frontal cortex and hippocampus of female rats,” – Pan Y. and others,
Proc Soc Exp Biol Med 1999
Jun;221(2):118-25.
— “Our data suggest that soy
phytoestrogens may function as estrogen agonists in regulating CHAT and NDF mRNBAs in the brain of
female rats.”
... / 42
- 42 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - There is an increased
breast tumor risk from foetal exposure to
Soy ... Carcinogen-induced mammary tumorigenesis.
1999 “Maternal
exposure to genistein during pregnancy increases carcinogen-induced mammary
tumorigenesis in female rat offspring,” – Hilakiviv-Clarke
L. & others,
Oncol Rep 1999 Sep-Oct;6(5):1089-95., Research
Bldg.,
— Dietary genistein was found
to enhance the growth of mammary gland tumors in mice.
— Increased breast tumor risk from foetal exposure to Soy ... Carcinogen-induced
mammary tumorigenesis.
— "A high estrogenic environment in utero may increase
subsequent breast cancer risk.
; i ; — It was therefore determined whether a
maternal exposure during pregnancy
to the phytoestrogen genistein or zearalenone, both of which exhibit estrogenic
activities in vitro and in vivo, alters breast cancer risk among female
offspring ... ...
--- The results indicate that in utero exposure to genistein,
but not to zearalenone, dose-dependently increased the incidence of
DMBA-induced mammary tumors, when compared with the controls. Tumor growth
characteristics were not altered ... ...
— Our results suggest that a maternal exposure to subcutaneous
administration of genistein can increase mammary
tumorigenesis in the offspring, mimicking the effects of in utero
estrogenic exposures.
— Further, increased ER protein levels and reduced PKC activity in
the mammary gland may be involved in increasing susceptibility to carcinogen-induced
mammary tumorigenesis in rats exposed to genistein in
utero."
i i i , i i i , i i i , i i i - DNA strand breaks - infantile acute leukemia (IAL) ...
-
http://www.soyonlineservice.co.nz/04immunefunction.htm
.
1999 “Infantile
leukemia and soybeans–a hypothesis,” – Abe
T., Leukemia
1999 Mar;13(3)317-20.,
; i ; —
Genistein from soybeans contributes to DNA strand breaks and may be “largely responsible” for infantile
acute leukemia.
— Recent molecular-genetic
studies have revealed that in the majority of patients with secondary
leukemia induced by
topoisomerase II (topo II) inhibitors and also with infantile acute leukemia
(IAL), the breakpoints
are clustered within scaffold attachment regions (SARs) of 3'-MLL-bcr near exon
9.
— Genistein, abundant in soybeans, is reported to be a potent
nonintercalative topo II inhibitor.
— It interferes with the break-reseal reaction of topo II by stabilizing a cleavable
complex, which in the presence of detergents, results in DNA
strand breaks. The
present study revealed that genistein induced chromatid-type aberrations, in
which chromatid exchanges are often observed.
— Genistein seems to act in a manner very similar to that of VP-16, although the latter is reported to
produce both chromatid- and chromosome-type aberrations.
— In view of this pharmacological similarity between genistein and
VP-16, and also the similarity of breakpoint clustering regions within the MLL
gene in reported cases with secondary leukemia and IAL, genistein may be
largely responsible for the development of IAL.
...
/ 43
- 43 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i
1999 “Hot flushes
and other menopausal symptoms in relation to soy product intake in Japanese
women,” – Nagata C. and others,
Climacteric 1999
Mar;2(1):6-12.
— Intake of fermented soy
products was found to reduce the severity of hot flashes in Japanese women, but
not total soy intake (from unfermented soy products such as are found in
western diets).
— This study is included because it contradicts assertions that
Japanese women do not suffer from hot flashes.
— Only fermented soy products had a minor effect and that was just with in the margin of
statistical error (ie.) it was more likely to be random chance !.
— Side note: All the promotions for soy for menopausal
relief were because Japanese women do not have a word for it. All that means is they don't talk about them. They have them all right. Look at this research.
2000 “Increased
induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats fed diets
containing purified genistein or genistein-rich soya protein,” – Gee J.M. and others,
Carcinogenesis 2000
Dec;21(12):2255-9.
— Genistein promotes induction
of aberrant crypt foci, by an as yet unidentified
mechanism when fed immediately before treatment with 1,2-dimethylhydrazine.
i i i
2000 “Comparative
effects of neonatal exposure of male rats to potent and weak (environmental)
estrogens on spermatogenesis at puberty and the relationship to adult testis
size and fertility: evidence for stimulatory effects of low estrogen levels,” –
Cassanova N. and others,
Endocrinology 2000
Oct;141(10):3898-907.
— Administration of genistein
to rats significantly retarded most measures of pubertal spermatogenesis.
Animals fed a soy-free diet had significantly larger testes than controls fed a
soy-containing diet.
— “It is concluded that ...
the presence or absence of soy or genistein in the diet has significant
short-term (pubertal spermatogenesis) and long-term (body weight, testis size,
FSH levels and possibly mating) effects on males.
i i i
2000 “Effects of
isoflavone supplement on healthy women,” – Watanabe
S. and others, Biofactors 2000;12(1-4):233-41.
— After one month of taking 20 mg or 40 mg isoflavones daily,
60% of the young women
had prolonged menstruation, 20% had shortened menstruation, 17% remained unchanged
and 3% became irregular. Other hormonal changes “suggest that isoflavones
influence not only estrogen receptor-related functions but the
hypothalamo-hypophysis-gonadal axis.”
... / 44
- 44 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - DNA breakage ... within
1 hour … of treatment ; i ;
2000 “Genistein
induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer
cells,” – Salti G.I. and others, Eur J Cancer
2000 Apr;36(6):796-802.
; i ; —
DNA breakage in colon
cancer cells occurred within 1 hour of treatment with genistein.
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
2000 “Phytoestrogens
decrease brain calcium-binding proteins but do not alter hypothalamic
androgen metabolizing enzymes in adult male rats,” – Lephard E.D. and others, Brain Res 2000 Mar 17;859(1):123-31.
— Animals fed diets containing
phytoestrogens ... for 5 weeks
... had elevated levels of phytoestrogens in the brain and a decrease of brain
calcium-binding proteins. Calcium-binding
proteins are associated with protections against neurodegenerative diseases.
i i i , i i i , i i i , i i i - infant
leukemia
- http://www.soyonlineservice.co.nz/downloads/strick.pdf
,
-
http://www.cancerpage.com/cancernews/cancernews704.htm
.
2000 “Dietary
bioflavonoids induce cleavage in the MLL gene and may contribute to infant
leukemai,” – Strick R. and others,” Proc Natl Acad Sci USA
2000 Apr
25;97(9):4790-5.
; i ; —
Researchers found that flavonoids, especially genistein, can cross the
placenta and induce cell changes that lead to infant leukemia.
i i i , i i i .
2000 “Dietary
genistein inactivates rat thyroid peroxidase in vivo without an apparent
hypothyroid effect,” – Chang H.S. and
Deorge D.R., Toxicol
Appl Pharmacol 2000 Nov 1;168(3):244-52.
— The activity of thyroid peroxidase activity in soy-fed
rats was reduced by up to 80% compared to those on a soy-free diet. As
thyroid hormone levels and thyroid weights were no different between treated
and untreated groups, the researchers concluded that “the remaining enzymatic
activity is sufficient to maintain thyroid homeostasis in the absence of
additional perturbations.” However, it is difficult or impossible to measure
some of the more subtle manifestations of hypothyroidism in rats.
2000 “Increased
induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats fed diet containing
purified genistein or genistein-rich soya protein,” – Gee J.M. and others, Carcinogenesis 2000;21:2255-2259.
— Rats fed the isoflavone
genistein exhibited
pathological changes in the colon.
i i i , i i i , i i i , i i i - Genistein in Soy is a
endocrine disruptor & induces mammary carcinoma
2000 “Influence of
perinatal genistein exposure on the development of MNU-induced mammary
carcinoma in female Sprague-Dawley rats,” –Yang
J. and others, Cancer Lett 2000 Feb 28;149(1-2):171-9., Department of Pathology II,
— “... perinatal genistein is an endocrine disrupter and increases
the multiplicity of MNU-induced mammary carcinoma in rats.”
... / 45
- 45 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - caused abnormal growth of the Thyroid gland.
2000 “Dramatic
synergism between excess soybean intake and iodine deficiency on the
development of rat thyroid hyperplasia,” – Ikeda
T. and others, Carcinogenesis
2000 Apr;21(4):707-13.
— Excess soybean intake with
iodine deficiency caused abnormal growth of the
Thyroid gland.
i i i , i
2000 “Inverse
association of soy product intake with serum androgen and estrogen
concentrations in Japanese men,” – Nagata
C. and others, Nutr
Cancer 2000;36(1):14-8.
— Researchers found lower testosterone levels and
higher estrogen levels in Japanese men who consumed higher
levels of soy foods.
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
2000 “Mass
Spectrometric determination of Genistein tissue distribution in diet-exposed
Sprague-Dawley rats,” – Chang H.C. and
others,
J Nutr 2000 Aug;130(8):1963-70., Division
of Biochemical Toxicology,
— Genistein administered to mice
via maternal milk or fortified feed showed dose-dependent increases in total genistein concentration in the brain, liver, mammary, ovary, prostate, testis, thyroid and uterus.
— Female liver contained the
highest amount of genistein (7.3 pmol/mg tissue) and male whole brain
contained the least (0.04 pmol/mg).
— These results for measured
amounts of genistein, present as aglycone and conjugates, in putative target
tissues provide a link with other studies in which blood concentrations
and physiologic effects of genistein are measured.
i i i , i i i , i i i - Genistein has adverse
effects on animal reproduction
2000 “Effects of
genistein exposure on sexually dimorphic behaviors in rats,” – Flynn K.M. and others,
Toxicol Sci 2000
Jun;55(2):311-9.
; i ; —
Noting that genistein “has adverse effects on animal
reproduction,” the
researchers administered genistein to pregnant rats and to their offspring
during growth. Results indicated significantly decreased body weight in
genistein-fed rats compared to controls. The results indicate that developmental
genistein treatment, at levels that decrease maternal and offspring body
weight, causes subtle alternations in some sexually dimorphic behaviors.
i i i , i i i
2000 “Effects of
replacing meat with soyabean in the diet on sex hormone concentrations in
healthy adult males,” – Habito R.C.
and others, Br
J Nutr 2000 Oct;84(4):557-63.
— Men eating tofu instead of
meat for 4 weeks had lower
testosterone-oestradiol ratios, as well as, changes in other hormone
levels. “Thus, replacement of meat
protein with soyabean protein, as tofu, may have a minor effect on
biologically-active sex hormones which could influence prostate cancer
risk.”
...
/ 46
- 46 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i - Soy protein isolate, SPI,
was found to accelerate puberty
2001 “Developmental
effects and health aspects of soy protein isolate, casein and whey in male and
female rats,” – Badger T.M. and others,
Int J Toxicol 2001
May-Jun;20(3);165-74.
— Feeding of soy protein isolate was found to accelerate
puberty in female rats.
Female rats also had reduced serum 17beta-estradiol concentrations.
i i i , i i i , i i i , i i i - Placental transfer to the foetal brain ... Genistein cross the
rat placenta and reaches
the fetal brain in doses simular to those
observed in humans ...
Also
see ... Frying the Brain With Soy
... page 63
2001 “Placental
transfer of the soy isoflavone genistein following dietary and gavage
administration to Sprague Dawley rats,” – Doerge
D.R. and others, Reprod
Toxicol 2001 Mar-Apr;15(2):105-10., Division
of Biochemical Toxicology, National Center for Toxicological Research, U.S.
FDA, Jefferson, AR 72079, USA.
; i ; —
Genistein was found to cross the rat placenta and
reach the fetal brain in doses similar to those observed in
humans.
i i i , i i i , i i i , i i i - Genistein is more
carcinogenic than DES - Diethylstilbestrol
2001 “Uterine
adenocarcinoma in mice treated neonatally with genistein,” – Newbold R.R. and others, Cancer Res 2001 Jun 1;61(11):4325-8., Developmental
Endocrinology Section, Laboratory of Toxicology, Environmental Toxicology
Program, Division of Intramural Research, National Institute of Environmental
Health Sciences, Research Triangle Park, NC, USA.
; i ; —
Genistein in soy was found to be more carcinogenic than DES,
especially during
“critical periods of differentiation
— “The developing fetus is uniquely sensitive to perturbation with
estrogenic chemicals. The carcinogenic effect of prenatal exposure to
diethylstilbestrol (DES) is the classic example. Because phytoestrogen use in
nutritional and pharmaceutical applications for infants and children is
increasing, we investigated the carcinogenic potential of genistein, a naturally occurring plant estrogen in soy,
in an experimental animal model previously reported to result in a
high incidence of uterine adenocarcinoma after neonatal DES exposure. Outbred
female CD-1 mice were treated on days 1-5 with equivalent estrogenic doses of
DES (0.001 mg/kg/day) or genistein (50 mg/kg/day). At 18 months, the
incidence of uterine adenocarcinoma was 35% for genistein and 31% for DES.
— These data suggest that genistein is carcinogenic if exposure occurs during critical periods
of differentiation. Thus, the use of soy-based infant formulas in the absence
of medical necessity and the marketing of soy products designed to appeal to
children should be closely examined".
2001 “Inhibitory
effect of genistein on the proliferation of the anterior pituitary cells of
rats,” – Zhang Q.H. and others,
Sheng Li Xue Bao 2001
Feb;53(1):51-4.
— In consequence, genistein, as a tyrosine kinase inhibitor, can
significantly inhibit the proliferation of pituitary cells possibly by inducing
apoptosis, and the tyrosine kinase activity may play a key role in the
proliferation and differentiation of pituitary cells.
— Genistein inhibits proliferation & causes apoptosis of pituitary cells by
inhibiting tyrosine kinase activity
... / 47
- 47 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
e
i i i , i i i , i i i , i i i - Stimulate breast
cancer growth ??. Yes
!!.
Women
with current or past breast cancer should be aware of the risks
of potential tumor growth when
taking soy products … antagonize the
effects of tamoxifen …”
2001 “Effects of soy
phytoestrogens genistein and daidzein on breast cancer growth,” – de Lemos M.L., Ann
Pharmacother 2001 Sep;35(9):1118-21., British Columbia Cancer Agency,
— Objective: to determine whether genistein and daidzein, the major phytoestrogens in soy, can
stimulate breast cancer growth ??.
; i ; — Women with current or past breast cancer should be aware of the risks
of potential tumor growth when taking soy
products.”
; i ; — Conclusions: Genistein and daidzein may stimulate existing breast tumor growth and antagonize the effects of tamoxifen.
i i i , i i i , i i i , i i i - stimulated breast
tumor growth and cell proliferation
2001 “Physiological
concentrations of dietary genistein dose-dependently stimulate growth of
estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude
mice,” – Ju Y.H. and others,
J Nutr 2001
Nov;131(11):2957-62., Department
of Food Science and Human Nutrition, University of Illinois at
Urbana-Champaign, Urbana, IL 61801, USA.
— Genistein stimulated breast tumor growth and cell proliferation in mice in a dose-responsive manner.
i i i , i i i , i
2001 “Urinary
phytoestrogens and postmenopausal breast cancer risk,” –
— “We were not able to detect the previously reported protective effects of genistein and enterolactone on
breast cancer risk in our postmenopausal population of Dutch women.”
i i i i
2001 “Reproductive
effects in male and female rats of neonatal exposure to genistein,” – Nagao T. and others,
Reprod Toxicol 2001
Jul-Aug;15(4):399-411.
— Feeding of genistein to
newborn rats resulted in lower body weight in male and female rats,
estrous cycle irregularities and lowered fertility in female rats. Neonatal exposure to genistein caused dysfunction of postpubertal
reproduction performance, as well as, abnormal development of
gonads in female but not
in male rats.
i i i , i i i - causes a decrease in testosterone levels in rainbow trout
2001 “Effect of
genistein-enriched diets on the endocrine process of gametogenesis and on
reproduction efficiency of the rainbow trout Oncorhynchus mykiss,” – Bennetau-Pelissero C. and others,
Gen Comp Endocrinol 2001
Feb;121(2):173-87.
— Genistein caused a decrease in testosterone levels in
rainbow trout. Testicular development was accelerated in genistein-fed fish
and sperm motility and concentration were decreased in a dose-dependent manner
at spawning.
... / 48
- 48 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - These effects occurred -within-
exposure ranges achievable in humans.”
2001 “Effects of
dietary genistein exposure during development on male and female DC
(Sprague-Dawley) rats,” – Declos K.B.,
Bucci T.J., Lomax L.G., and others, Reprod Toxicol 2001 Nov;15(6):647-63., Division of Biochemical Toxicology, NCTR,
— Genistein
was administered to rats at various concentrations starting on gestation day 7
and continuing throughout pregnancy, lactation and growth of the pups to day
50. The genistein-fed rats showed a number of variances from the norm: lower
weight in both sexes; decreased prostate weight in males; higher pituitary
gland to body weight ratios in both sexes; hyperplasia of the mammary glands,
abnormal ovarian antral follicles and
abnormal cellular maturation in the vagina in females; aberrant or delayed
spermatogenesis and deficit sperm in
males; and an increase in the incidence and/or severity of renal tubal
mineralization in both sexes, even at low doses. “Dietary genistein
thus produced effects in multiple estrogen-sensitive tissues in males and
females that are generally consistent with its estrogenic activity.
; i ; ---
These effects occurred - within - exposure ranges achievable in
humans.”
i i i , i i i , i i i , i i i - Dietary levels of daidzein and genistein
were associated with an increase
in the incidence of vulvar carcinomas in mice
2001 “Effects of the
dietary phytoestrogens daidzein and genistein on the incidence of vulvar
carcinomas in 129/J mice,” – Thigpen
J.E. and others, Cancer
Detect Prev 2001;25(6):527-32. Comparative
Medicine Branch, National Institute of Environmental Health Sciences,
— The objective of this study was to determine the effect of
dietary phytoestrogens on the incidence of spontaneous vulvar carcinomas in
129/J mice using three
natural ingredient diets and two purified diets containing predetermined levels
of daidzein and genistein. Vulvar carcinomas in representative
groups of mice were confirmed using routine histological procedures..
— Within one month, the incidence of vulvar
carcinomas in mice fed a modified soy protein diet was significantly increased
over those of mice fed control diets.
— Within 3 months, the incidence of vulvar carcinomas in mice
fed the soy protein diet was significantly increased over those of mice fed
other control diets.
— “We concluded that dietary levels of daidzein and genistein
were associated with an increase in the incidence of vulvar
carcinomas in mice, and that the 129/J mouse
may provide an animal model for studying the development of vulvar carcinomas.
i i i , i i i , i
2001 “Gender-based
differences in rats after chronic dietary exposure to genistein,” – Slikker W. Jr. and others,
Int J Toxicol 2001
May-Jun;20(3):175-9.
— Dose-related alternations of
the volume of the sexually dimorphic nucleus of the medial preoptic area were
observed in genistein-exposed male rats but not females.
— Gender-based differences can be observed from pharmacokinetic,
behavioral, or anatomical assessments.
No single assessment tool will provide a complete answer, but the use of
a variety of indices, each with known gender-related outcome differences, can
reveal agent-induced gender-based alterations.
— These observations describe
the utility of a variety of gender-based assessment tools and indicate that
dose-related effects of developmental and chronic dietary exposure to genistein
can be observed in the rodent. Additional
studies, perhaps in nonhuman primates, are necessary to further predict
the effect(s) of genistein on human gender-based development.
... /
49
- 49 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - stimulate the growth
of “estrogen-dependent breast cancer cells”
Depending on processing, soy
protein isolates, SPI’s, vary widely in concentrations of genistein
2001 “Soy diets
containing varying amounts of genistein stimulate growth of estrogen-dependent
(MCF-7) tumors in a dose-dependent manner,” – Allred C.D. and others, Cancer Res 2001 Jul 1;61(13):5045-50. Department of Food Science and Human
Nutrition,
Depending on processing, soy
protein isolates, SPI’s, vary widely in concentrations of genistein
; i ; Here
we present new information that soy protein isolates
containing increasing concentrations of genistein stimulate
the growth of estrogen-dependent breast cancer cells
in vivo in a dose-dependent manner.
i i i , i i i , i i i , i i i , i - Removal of soy genistin ... caused tumors
to regress.
2001 “Dietary
genistin stimulates growth of estrogen-dependent breast cancer tumors similar
to that observed with genistein,” – Allred
C.D. and others, Carcinogenesis
2001 Oct;22(10):1667-73. Depart. of Food Science & Human
Nutrition, and Division of Nutritional Sciences, Univ. of
— Genistin, the glycoside form
of genistein, is converted to genistein by human saliva. The glycoside
genistin, like the aglycone genistein, can stimulate
estrogen-dependent breast cancer cell growth in vivo. Removal of genistin or
genistein from the diet caused tumors to regress.
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
2001 “Dietary soy
phytoestrogen effects on brain structure and aromatase in Long-Evans
rats,” – Lephart E.D. and others,
Neuroreport 2001
Nov 16;12(16):3451-5.
— Dietary phytoestrogens
significantly decrease body and prostate weights and during adulthood
significantly change the structure of the sexually dimorphic brain region in male but not in female rats.
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
- Soy Isoflavone supplements antagonizes
reproductive behavior
- lowers Sex drive
2001 “Soy isoflavone
supplements antagonize reproductive behavior and estrogen receptor alpha- and
beta-dependent gene expression in the brain,” – Patisual H.B. and others, Endocrinology 2001 Jul;142(7):2946-52.
; i ; —
Soy lowers Sex drive
— Soy isoflavones interfere
with estrogen receptors
in the adult female rat brain resulting in a significant decrease in receptive behavior
in estrogen- and progesterone-primed females.
— “The observed disruption of
sexual receptivity by isoflavone supplement is probably due to antiestrogenic
effects observed in the brain.”
— These results suggest that
isoflavone phytoestrogens are antiestrogenic on both ERalpha- and
ERbeta-dependent gene expression in the brain and estrogen-dependent behavior.
... / 50
- 50 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i - disruption of gene
expression continued 3 months after
... into adulthood
2001 “Neonatal
exposure to genistein reduces expression of estrogen receptor alpha and
androgen receptor in testes of adult mice,” – Shibayama T. and others, Endocr J 2001 Dec;48(6):655-63. Core
Research for Evolutional Science and
— “Our results exhibited that
the disruption of gene expression continued for long term such as ... 3 months after administration of genistein ... even if no effect was found at
conventional reproductive-toxicological levels.
We have shown that neonatal administration of weak estrogenic compound
(genistein) affects male reproductive organs at
molecular levels in adulthood.”
i i i , i i i , i i i , i i i - Humans are affected at lower doses than rodents.
. “In vivo data
show that phytoestrogens have a wide range of biologic effects at doses and
plasma concentrations seen with normal human diets. Significant in vivoresponses have been
observed in animal and human tests for bone, breast, ovary, pituitary,
vasculature, prostate, and serum lipids.”
2001 “Cross-species
and interassay comparisons of phytoestrogen action,” – Whitten P.L., Patisaul H.B., Environ Health Perspect 2001 Mar;109 Suppl 1:5-20., Department
of Anthropology, Emory University, Atlanta, Georgia 03022, USA.
; i ; Humans are
affected at lower doses than rodents.
— “In vivo data show that
phytoestrogens have a wide range of biologic effects at doses and plasma
concentrations seen with normal human diets.
Significant in vivo responses have been observed in
animal & human tests for ... bone
... breast ... ovary ... pituitary ... vasculature
... prostate and serum lipids ...
Steroidogenesis and the hypothalamic-pituitary-gonadal axis appear to be
important loci of phytoestrogen actions, but these inferences must be tentative because good dose-response
data are not available for many end points.”
— This paper compiles animal and human data on the biologic
effects and exposure levels of phytoestrogens in order to identify areas of
research in which direct species comparisons can be made. "In vivo data show that phytoestrogens
have a wide range of biologic effects at doses and plasma concentrations seen
with normal human diets. Significant
in vivoresponses have been observed in animal and human tests for bone, breast,
ovary, pituitary, vasculature, prostate, and serum lipids."
— The similarity of reported
proliferative and antiproliferative doses illustrates the need for fuller examination of dose-response
relationships and multiple end points in assessing phytoestrogen actions.
i i i , i i i
2002 “Assessing
estrogenic activity of phytochemicals using transcriptional activation and
immature mouse uterotrophic responses,” – Jefferson
W. and others, J
Chromatogr B Analyt Technol Biomed Life Sci 2002
Sep 25;777(1-2):179.
— Genistein caused an increase
in uterine weight and several other indications of estrogenicity.
i i
2002 “Oxidative
metabolism and genotoxic potential of major isoflavone phytoestrogens,” – Kulling S. and others,
J Chromatogr B Analyt Technol Biomed Life
Sci 2002 Sep 25;777(1-2):211.
— The study describes the potential
genetic toxicity of the breakdown products of soy isoflavones.
... / 51
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
e
i i i , i i i - Genistein directly inhibits
steroid-production enzymes.
2002 “Acute and
chronic effects of genistein, tyrphostin and lavendustin A on steroid synthesis
in luteinized human granulosa cells,”
– Whitehead
— Genistein directly inhibits
steroid-production enzymes.
i i i , i i i , i i i , i i i , i
-
implications for reproductive toxicity & carcinogenesis
- warrants further investigation
-
further study of auto-immune thyroiditis
in children consuming Soy formula is warranted
2002 “Inactivation
of thyroid peroxidase by soy isoflavones, in vitro & in vivo,”– Doerge D.R. & Chang H.C.,
J Chromatogr B Analyt Technol Biomed Life
Sci 2002 Sep 25;777(1-2):269-79., Division
of Biochemical Toxicology, National Center for Toxicological Research, 3900
NCTR Road, Jefferson, AR 72079, USA.
— studies of soy isoflavones
in experimental animals suggest possible adverse effects as ... enhancement of
reproductive organ cancer, modulation of endocrine function, anti-thyroid
effects.
— The paper reviews
the evidence in humans & animals for anti-thyroid effects of soy & its
principal isoflavones, genistein & daidzein. Genistein interferes with estrogen
receptors in rat prostate glands which “. . . may have implications for reproductive toxicity & carcinogenesis that warrant further investigation”
— Also “... further study of autoimmune thyroiditis
in children consuming soy formula is warranted ...”.
i i i , i i i , i i i , i i i
2002 “Detection of
phytoestrogens in samples of second trimester human amniotic fluid,” – Foster W.G. and others, Toxicol Lett
2002 Mar 28;129(3):199-205., Center for
Women's Health,
— The study describes a method
for measuring phytoestrogens daidzein and genistein in amniotic fluid.
Such tests are needed, the authors assert, because “There
is widespread concern that fetal exposure to hormonally active chemicals may adversely
affect development of the reproductive tract.”
i i i , i i i , i i i , i i i - the results were
additive ... joint action of estrogenic chemicals lead to
significant
underestimations of risk.
… ; i ; … ; i ; … ; i ;
2002 ““Something
from “nothing” - - eight weak estrogenic chemicals combined at concentrations
below NOECs produce significant mixture effects,” – Silva E. and others, Environ Sci Technol 2002 Apr;36(8):1751-6., Centre
for Toxicology, Department of Pharmacology, The School of Pharmacy, University
of London.
; i ; — Xenoestrogens including genistein were tested in combinations. The results were additive,
producing significant effects when combined at low concentrations.
“We conclude that estrogenic agents are able to act together to produce
significant effects when combined at concentrations below their NOEC’s. Our
results highlight the limitations of the traditional focus on the effects of
single agents. Hazard
assessments that ignore the possibility of joint action of estrogenic chemicals
will almost certainly lead to significant underestimations of risk.”
... / 52
- 52 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - ; i ; - Overwhelmes
effects of Tamoxifen, Therefore …
Caution …
is warranted
2002 “Dietary
genistein negates the inhibitory effect of tamoxifen on growth of
estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic
mice,” – Ju Y.H. and others,
Cancer Res 2002
May 1;62(9):2474-7., Department of Food Science and Human
Nutrition, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801,
USA.
; i ; — The use of “dietary isoflavone
supplements” by postmenopausal women “with breast cancer” is
increasing.
— Dietary genistein negated or overwhelmed the inhibitor effect of tamoxifen on MCF-7 tumor growth,
lowered E2 levels in plasma, and increased expression of E-response genes
(e.g., pS2, PR, and cyclin D1) in ovariectomized and athymic mice. …
; i ; --- “Therefore, caution is warranted for postmenopausal women consuming
dietary genistein while on TAM therapy for E-responsive breast cancer.”
i i i , i i i , i i i - Genistein caused a decrease in the percentage of helper T cells
2002 “Genistein
modulates splenic natural killer cell activity, antibody-forming cell response
and phenotypic marker expression in F(0) and F(1) generations of Sprague-Dawley
rats,” – Guo T.L. and others,
Toxicol Appl Pharmacol 2002
Jun 15;181(3):219-27.
— Genistein caused a decrease
in the percentage of helper T cells
and an increase in the relative weights of spleen and thymus in rats.
i i i , i i i , i i - safety testing of natural products, including soy products, is not
required
2002 “Goitrogenic
and estrogenic activity of soy isoflavones,” – Doerge D.R. and D.M. Sheehan, Environ Health Perspect 2002
Jun;110 suppl 3:349-53., Division
of Biochemical Toxicology, National Center for Toxicological Research,
Jefferson, Arkansas, USA.
— “Soy is known to produce
estrogenic isoflavones. Here, we briefly review the evidence for binding of
isoflavones to the estrogen receptor, in vivo estrogenicity and developmental
toxicity, and estrogen developmental carcinogenesis in rats. Genistein, the major soy
isoflavone, also has a frank estrogenic effect in women. We then focus on evidence from animal and human studies suggesting a link between soy consumption
and goiter, an activity independent of estrogenicity. Iodine deficiency greatly
increases soy antithyroid effects, whereas iodine supplementation is
protective. ... Although safety testing of natural
products, including soy products, is not required, the possibility that widely
consumed soy products may cause harm in the human population via either or both
estrogenic and goitrogenic activities is of concern.”
i i i , i i i , i i i
2002 “Genistein affects
ER beta- but not ER alphadependent gene expression in the hypothalamus,” – Patisaul H.B. and others,
Endocrinology 2002
Jun;143(6):2189-97.
— Genistein at a dietary
concentration of 100 or 500 ppm had no
effect on lordosis behavior in rats. However,
at 500 ppm genistein had differential activity through ER alpha and ER beta in
the hypothalamus.
... / 53
- 53 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i
2002 “The specific
role of isoflavones on estrogen metabolism in premenopausal women,” – Kumar N.B. and others,
Cancer 2002
Feb 15;94(4):1166-74.
Sixty eight women consuming 40
mg soy isoflavones daily for 12 weeks had changes in steroid hormones and increased cycle length.
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
- Premature Anovulation in Female Offspring
& Suppressed Sexual Behavior in Males.
-
can alter estrogen-dependent gene
expression in the brain and complex behavior.
-
Small exposure levels can alter
estrogen-dependent gene expression in the brain
and complex behavior
2002 “Neurobehavioral
actions of coumestrol and related isoflavonoids in rodents, – Whitten P.L. and others,”
Neurotoxicol Teratol 2002
Jan-Feb;24(1):47-54.
; i ; —
Coumestrol and related isoflavones induced neurobehavioral actions in rodents that were antiestrogenic, either
antagonizing or producing an action in opposition to that of estradiol. “This work demonstrates that even
small, physiologically relevant, exposure levels can alter
estrogen-dependent gene expression in the brain and complex behavior.
i i i , i i
2002 “Effects of soy
consumption on gonadotropin secretion and acute pituitary responses to
gonadotropin-releasing hormone in women,” – Nicholls
J. and others,
J Nutr 2002
Apr;132(4):708-14.
— 12 women consumed 60 mg
isoflavones daily for 10-14 days. A residual postmenopausal effects was seen in
postmenopausal subjects. “In one
premenopausal woman, enhanced LH secretion was observed after soy treatment, suggesting
there may be subpopulations of women are highly sensitive to isoflavones.”
i i
2002 “Combined
effects of dietary phytoestrogen and synthetic endocrine-active compounds on
reproductive development in Sprague-Dawley rats: genistein and methoxychlor,” –
You L. and others, Toxicol
Sci 2002
Mar;66(1):91-104.
— “Data from this study
indicate that phytoestrogens are capable of altering the toxicological
behaviors of other EACs, and the interactions of these compounds may involve
complexities that are difficult to predict based on their in vitro steroid
receptor reactivities.”
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
2002 “Neurobehavioral
actions of coumestrol and related isoflavonoids in rodents,” – Whitten P.L. and others,
Neurotoxicol Teratol 2002
Jan;24(1):47-54.
— Treatment of female rats
with coumestrol (a phytoestrogen found in soy) induced premature anovulation
in female offspring and suppressed sexual behavior in male offspring. Various hormonal effects were observed
with even small doses. “.. . even small, physiologically relevant exposure levels can
alter estrogen-dependent gene expression in the brain and complex behavior.”
... / 54
- 54 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i - the potential for soy
isoflavones to cause heart arrhythmias.
2002 “Genistein
Inhibits the Inward Rectifying Potassium Current in Guinea Pig Ventricular
Myocytes,” – Chiang C.E. and others,
J Biomed Sci 2002;9:321-326.
— Dietary isoflavones
genistein dose-dependently and reversibly inhibit the inward rectifying K+
(potassium) current in guinea pigs ventricular myocytes, suggesting the
potential for soy isoflavones to cause heart arrhythmia’s.
i i i , i i i , i i i , i - the placenta does not
represent a barrier
2002 “Transplacental
transfer of the phytoestrogen daidzein in DA/Han rats,” – Degen G.H. and others, Arch Toxicol 2002 Feb;76(1):23-9., Institute
fur Arbeitsphysiologie an der Universitat Dortmund, Ardeystrasse 67, 44139
Dortmund, Germany.
— The research found
indications of a rapid
transfer of daidzen from the mother to the fetus, but also that efficient extraction of
daidzein from the maternal blood occurs. “Since dietary phytoestrogens account
for a significant proportion of human exposure to potential endocrine
modulators, and since the placenta does not represent a
barrier to daidzein or related estrogenic isoflavones, the consequences of
these exposures early in life should be examined and monitored carefully.”
i i i , i i i , i i i , i i i - It is therefore
considered likely that similar or larger effects may occur
in
human male infants fed infant soy milk formula
2002 “Infant feeding
with soy formula milk: effects on the testis and on blood testosterone levels
in marmoset monkeys during the period of neonatal testicular activity,” – Sharp R.M. and others,
Hum Reprod 2002
Jul;17(7):1692-703. MRC
Human Reproductive Sciences Unit, Centre for Reproductive Biology, 37 Chalmers
Street, Edinburgh EH3 9ET, UK., r.sharpe@hrsu.mrc.ac.uk
; i ; —
Infant male marmoset monkeys were fed either soy-based or milk-based
formula. The neonatal testosterone rise
was suppressed in the soy-fed monkeys.
Levels of isoflavone in the monkey diets were 40-87% of that reported in
4-month human infants fed a 100% soy-based formula diet. “It is therefore considered likely
that similar, or larger, effects to those shown here in marmosets may occur in
human male infants fed with SFM [soy formula milk].”
i i i , i i i , i i i , i i i - Carcinogenic
-
http://www.eurekalert.org/pub_releases/2001-05/NIoE-Iucs-3005101.php
.
2002 “Increased
uterine cancer seen in mice injected with genistein, a soy estrogen, as
newborns,” – Newbold R. and others,
Cancer Research 2002
June.
— Infant mice given genistein
developed cancer of the uterus later in life.
; i ; —
“The data suggest that genistein is carcinogenic if exposure occurs during critical
periods in a young animal’s development.”
... / 55
- 55 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i - women ... hot flushes,
night sweats, and viginal dryness did not
improve in the soy group.
2002 “A pilot study
of the effects of phytoestrogen supplementation on postmenopausal endometrium,”
– Balk J.L. and others,
J Soc Gynecol Investig 2002
Jul-Aug;9(4)238-42., Department
of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens’
Hospital, University of Pittsburgh,
Pennsylvania 15213, USA.
— This was a double-blinded,
randomized, placebo-controlled trial comparing the effects of 6 months of dietary
phytoestrogen supplementation versus placebo in postmenopusal women.
; i ; —
“Phytoestrogens did not cause stimulation of the endometrium. Insomnia was more
frequent over the 6-month study in the soy group, where as - hot
flushes, night sweats and vaginal dryness improved from baseline in the placebo
group but not in the soy group.”
i i i , i i i , i i i , i i i - Thymic & immune
abnormality
- http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.mercola.com/2002/jun/8/soy.htm
, “Soy Weakens Your Immune System” ...
Dr. Mercola’s Comment ...
“It is quite amazing that this study was actually published, as the findings
were quite negative for Soy, and yet it was funded
by the United Soybean Board and
the Illinois Council on Food and Agricultural Research
.”
2002 “The
phytoestrogen genistein induces thymic and immune changes: a human health concern
?,” – Yellayka S. and others,
Proc Natl Acad Sci USA 2002
May 28;99(11):7616-21. Department of Veterinary Biosciences,
; i ; —
Genistein injections in ovariectomized adult mice produce dose-responsive
decreases in thymic weight of up to 80%. Genistein decreased thymocyte numbers
up to 86% and doubled apoptosis.
— There was a corresponding
reduction in splenic cells. The does that caused significant thymic and
immune changes in mice was comparable to those reported in soy-fed human
infants. “These results raise the possibility that serum genistein
concentrations found in soy-fed infants may be capable of producing thymic and
immune abnormalities, as suggested by previous reports of immune impairments in
soy-fed infants.”
i i i , i i i , i i i , i i - Also see ... Frying the Brain With Soy
... page 63
- short
interval of consumption can significantly alter sexually dimorphic brain regions,
anxiety, learning and memory ...
Alzheimer’s disease, especially in women.
2002 “Neurobehavioral
effects of dietary soy phytoestrogens,” – Lephard
E.D. and others, Neurotoxicol
Teratol 2002 Jan-Feb;24(1):5-16.
— Male mice fed diets rich in
phytoestrogens had lower levels of maze performance than male mice fed diets
free of phytoestrogens. (Opposite results were observed in female mice.)
— The results indicate that
consumption of dietary phytoestrogens resulting in very high plasma isoflavone
levels, (in many cases, over a relatively - short - interval
of consumption in adulthood), can significantly alter sexually dimorphic
brain regions, anxiety, learning and memory.
— The findings of these
studies identify the biological actions of phytoestrogens, specifically
isoflavones and their metabolites, found in animal soy-containing diets on brain and
behavior and implicate the importance of phytoestrogens given the recognized
significance of estrogens in brain and neural disorders, such as Alzheimer's
disease, especially in women.
... / 56
- 56 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
*****************************************************************
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(+) 85(+) - Extra Abstract Summaries
and also Toxic,
Poisonous “Plant Sterols”
i i i , i i i , i i - Injected genistein also causes decreased
humoral immunity
genistein
induces thymic atrophy
2003 “The
phytoestrogen genistein suppresses cell-mediated immunity in mice,” – Yellayi S., Zakroczymski M.A., Selvaraj V. and others,
— The soy phytoestrogen, genistein,
induces thymic atrophy when administered to ovariectomized mice by injection or in the
diet. Injected genistein also causes decreased humoral
immunity, but the effects
of genistein on cell-mediated immunity have not been addressed. ScienceMember
writes ... The soy phytoestrogen, genistein, induces
thymic atrophy when
administered to ovariectomized mice by injection or in the diet.
Injected genistein also causes decreased humoral immunity, but the effects of
genistein on cell-mediated immunity have not been addressed.
i i i , i i i , i i i , i i i - Daily administration of
72 mg of soy-derived isoflavones is no more
effective
than placebo in
reducing hot flushes in postmenopausal women.
2003 “Effect of
soy-derived isoflavones on hot flushes, endometrial thickness, and the
pulsatility index of the uterine and cerebral arteries,” – Penotti M., Fabio E., and others, Fertil Steril 2003 May;79(5):1112-1117., Second Department
of Obstetrics and Gynecology of the University of Milan, Milan, Italy.
; i ; —
To determine the effect of soy-derived isoflavones on hot flushes, endometrial
thickness, and the vascular reactivity of uterine and cerebral arteries. Double-blind,
randomized, placebo-controlled trial. Healthy volunteers in an
academic research environment. Sixty-two postmenopausal women aged 45-60 years
attending the Outpatient Menopause Clinic of our gynecological
departments. The patients were
administered 72 mg of soy-derived isoflavones or placebo under double-blind
conditions. The daily number of hot
flushes was recorded in a diary ... Both treatments led to a 40% reduction in
the number of hot flushes. Soy-derived
isoflavones had no effect on endometrial thickness or the PI of the uterine and
cerebral arteries.
— The daily administration of 72 mg of soy-derived isoflavones
is no more effective than placebo in reducing hot flushes in postmenopausal
women.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
... / 57
- 57 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i - Potential relationships
of endocrine disrupters and urogenital abnormalities
thought
to be increasing in incidence in boys and men
2003 “Exposure to
genistein during gestation and lactation demasculinizes the reproductive system
of rats,” – Wisniewski A.B., Klein
S.L., and others, J Urol 2003 Apr, 169(4):1582-6., Division of
Pediatric Endocrinology, Dept of Pediatrics, The John Hopkins School of
Medicine, Baltimore, Maryland, USA
— PURPOSE:
Exposure to the phytoestrogen genistein (Indofine Chemical Co.,
— CONCLUSIONS:
Perinatal genistein exposure results in transient and lasting alterations in
masculinization of the reproductive system. These results extend our
knowledge of the effects of early genistein exposure on male development and may
have implications for human health in terms of potential relationships
of endocrine disrupters and urogenital abnormalities thought to be increasing
in incidence in boys and men.
i i i , i i i , i i i , i - The effects of genistein
continued long after the rats were exposed
-
http://www.eurekalert.org/pub_releases/2003-03/jhmi-cis031003.php
.
2003 “Chemical in
soy alters reproductive organs in male rats,” – Wisniewski, Klein, John P., Gearhart M.D., Yegappan Lakshmanan, EurekAlert
— Researchers at the Johns
Hopkins Children's Center and the Johns Hopkins Bloomberg School of Public
Health report that male rats whose mothers were fed diets
containing genistein, a chemical found in soybeans, developed abnormal
reproductive organs and experienced sexual dysfunction as adults.
— While these findings do not
indicate that genistein has a similar effect in humans, researchers say the increasing
popularity of soy and soy-based foods, such as tofu and some infant formulas,
may warrant further research to determine if genistein exposure in the womb and
during breast-feeding influences human reproductive development.
; i ; — “The effects of genistein continued long after the rats were
exposed, leading us to believe that exposure to
this plant-derived estrogen during reproductive development can have long-term
detrimental effects in males,” said the study's lead author, Amy B. Wisniewski, Ph.D., a
researcher at the Johns Hopkins Children's Center.
— “Genistein may act as an estrogen or an anti-androgen, blocking
the function of endogenous androgens –– the sex hormones necessary for males to
develop a normal reproductive system –– and ultimately leading to the
reproductive abnormalities and sexual dysfunction we saw in the exposed rats,” added study co-author Sabra L. Klein,
Ph.D., of the School of Public Health. "However, additional research is
needed to determine if this is the case."
n
2003 “Soya
phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male
rats,” — File S.E., Hartley D.E., Alom
N., Rattray M.,
Neurosci Lett., 2003 Feb 27;338(2):135-8. Psychopharmacology Research Unit and
Biochemical Neuropharmacology Group, Centre for Neuroscience Research, King's
College
— Adult male hooded Lister
rats were either fed a diet containing 150 microg/g soya phytoestrogens or a
soya-free diet for 18 days. This concentration of phytoestrogens should have
been sufficient to occupy the oestrogen-beta, but not the oestrogen-alpha,
receptors.
— Using in situ hybridisation, significant reductions were found in
brain-derived neurotrophic factor (BDNF) mRNA expression in the CA3 and CA4
region of the hippocampus and in the cerebral cortex in the rats fed the diet
containing phytoestrogens, compared with those on the soya-free diet.
— No changes in glutamic acid
decarboxylase-67 or glial fibrillary acidic protein mRNA were found. This
suggests a role for oestrogen-beta receptors in regulating BDNF mRNA
expression.
... / 58
- 58 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - genistein ... daidzein ...
suggesting the possible involvement of mutagenicity
in
the initiation of ... “phytoestrogen-induced carcinogenesis.”
2003 “Cell-transforming
activity and mutagenicity of 5 phytoestrogens in cultured mammalian cells,” – Tsutsui T, Yagi E, and others, Int J Cancer 2003 Jun 20;105(3):312-20., Department of
Pharmacology,
— For the simultaneous
assessment of in vitro carcinogenicity and mutagenicity of
phytoestrogens, the
abilities of 5 phytoestrogens, daidzein, genistein, biochanin A, prunetin, and coumestrol, to
induce cell transformation and genetic effects were examined using the Syrian
hamster embryo (SHE) cell model. Cellular growth was inhibited by all
phytoestrogens in a concentration-related manner. The growth inhibitory effect
of the compounds was ranked: genistein, prunetin > coumestrol > biochanin
A > daidzein, which did not correspond to their apoptosis-inducing
abilities. Morphological transformation in SHE cells
was elicited by all phytoestrogens, except, prunetin. The
transforming activities were ranked as follows: genistein > coumestrol >
daidzein > biochanin A. Somatic mutations in SHE cells at the Na(+)/K(+)
ATPase and hprt loci were induced only by genistein, coumestrol, or daidzein.
Chromosome aberrations were induced by genistein or coumestrol, and aneuploidy
in the near diploid range was occurred by genistein or biochanin A. Genistein,
biochanin A or daidzein induced DNA adduct formation in SHE cells with the
abilities: genistein > biochanin A > daidzein.
Prunetin was negative for any of these genetic endpoints.
— Our results provide evidence that ... genistein ... coumestrol ... daidzein
... and biochanin A ... induce
cell transformation in SHE cells and that the transforming activities of these
phytoestrogens correspond to at least 2 of the mutagenic effects by each
phytoestrogen, i.e., gene mutations, chromosome aberrations, aneuploidy or DNA
adduct formation, suggesting the possible involvement of mutagenicity in the
initiation of phytoestrogen-induced carcinogenesis.
n
i i i , i i i , i i i , i i i - Perinatal genistein
exposure results in transient and lasting alterations in
masculinization
of
the reproductive system.
- may have implications for human health
in terms of potential relationships of endocrine disrupters and urogenital
abnormalities thought to be increasing in incidence in boys and men.
2003 “Exposure to
Genistein During Gestation and Lactation Demasculinizes the Reproductive System
in Rats,” — Wisniewski AB, Klein SL
and others.,
J Urol 2003 Apr;169(4):1582-1586, Division of Pediatric Endocrinology,
Department of Pediatrics, The Johns Hopkins School of Medicine, Baltimore,
Maryland, USA.
—
PURPOSE: Exposure to the phytoestrogen
genistein (Indofine Chemical Co.,
— MATERIALS AND METHODS: Female rats were fed a phytoestrogen-free
diet supplemented with no genistein (free), a low genistein dose (low) or a
high genistein dose (high) throughout gestation and lactation. Anogenital
distance of male offspring was measured weekly from postnatal days 2 to 21. At
puberty (postnatal day 40 to 45) preputial separation, and testis length and
width of male offspring were measured. At age 70 days reproductive organ
masses, plasma testosterone concentration, sperm counts and sexual behavior
were assessed in male offspring.
— RESULTS: Exposure to genistein resulted in temporary, prepubertal
urogenital abnormalities at postnatal days 21 and 40. Males
exposed to genistein had smaller anogenital distance and testis size, and
delayed preputial separation. Perinatal exposure to genistein also caused
long-term dysfunction in reproductive behavior, in which adult males exposed to
genistein were less likely to mount, intromit and ejaculate during mating
tests. Males exposed to genistein also had lower testosterone concentrations in
adulthood.
; i ; ---
CONCLUSIONS: Perinatal genistein exposure results in
transient and lasting alterations in masculinization of the reproductive
system. These results extend our knowledge of the effects of early genistein
exposure on male development and may have implications for human health in
terms of potential relationships of endocrine disrupters and urogenital
abnormalities thought to be increasing in incidence in boys and men.
... / 59
- 59 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
n
i i i , i i i , i i i , i i i -
2003 “Phytoestrogen
supplements for the treatment of hot flashes: the Isoflavone Clover Extract
(ICE) study: a randomized controlled trial,” — Tice J.A., Ettinger B., Ensrud K., and others., JAMA. 2003 Jul 9;290(2):207-14., Division of General
Internal Medicine, Department of Medicine, University of California, San Francisco
94143, USA.
—
CONTEXT: Clinical trials demonstrating increased
risk of cardiovascular disease and breast cancer among women randomized to
hormone replacement therapy have increased interest in other therapies for
menopausal symptoms.
Dietary supplements containing isoflavones are widely used as alternatives to
hormonal therapies for hot flashes, but there is a paucity of data supporting
their efficacy.
—
OBJECTIVE: To compare the
efficacy and safety of 2 dietary supplements derived from red clover with
placebo in symptomatic menopausal women.
— DESIGN,
SETTING, AND PARTICIPANTS:
Randomized, double-blind, placebo-controlled trial of menopausal women, aged 45
to 60 years, who were experiencing at least 35 hot flashes per week. The study
was conducted between November 1999 and March 2001 at 3
—
INTERVENTION: After a
2-week placebo run-in, 252 participants were randomly assigned to Promensil (82
mg of total isoflavones per day), Rimostil (57 mg of total isoflavones per
day), or an identical placebo, and followed-up for 12 weeks.
— MAIN
OUTCOME MEASURE: The
primary outcome measure was the change in frequency of hot flashes measured by
participant daily diaries. Secondary outcome measures included changes in quality
of life and adverse events.
—
RESULTS: Of 252
participants, 246 (98%) completed the 12-week protocol. The reductions in mean
daily hot flash count at 12 weeks were similar for the Promensil (5.1),
Rimostil (5.4), and placebo (5.0) groups. In comparison with the placebo group,
participants in the Promensil group (41%; 95% confidence interval [CI],
29%-51%; P =.03), but not in the Rimostil group (34%; 95% CI, 22%-46%; P =.74)
reduced hot flashes more rapidly. Quality-of-life improvements and adverse events
were comparable in the 3 groups.
— CONCLUSION:
Although the study provides some evidence for a biological effect of Promensil,
neither supplement had a clinically important effect on hot flashes or other
symptoms of menopause.
... / 60
- 60 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
n
i i i , i i i , i i i , i i i , (+) i i i - at levels comparable to the ranges of human
exposure
2004 “Effects of
genistein or soy milk during late gestation and lactation on adult uterine
organization in the rat,” – Hughes CL,
Liu G, and others,
Exp Biol Med (
; i ; Malnutrition
... from ...
False Nutritional Beliefs
— These experiments demonstrate that developmental exposure to
dietary isoflavones, at
levels comparable to the ranges of human exposure, modify expression of the
estrogen-regulated PR in the uterus of sexually mature rats weeks after
exposure ended.
— In utero and lactational
exposure to estrogenic agents
has been shown to influence
morphological and functional development of reproductive tissues. Thus,
consumption of dietary phytoestrogens, such as isoflavones, during pregnancy
and lactation could influence important periods of development, when the fetus
and neonate are more sensitive to estrogen exposure.
— In this study, reproductive
outcomes after developmental exposure to isoflavones were examined in
Long-Evans rats maternally exposed
to isoflavones via a commercial soy beverage or as the isolated isoflavone,
genistein. … … .
— Since the PR is essential for
regulating key female reproductive processes, such as uterine proliferation,
implantation, and maintenance of pregnancy, its increased expression suggests that soy phytoestrogen exposure during
reproductive development may have long-term reproductive health consequences.
n
i i i , i i i , i i i , i i i , (+) i i i -
2004 “Increased
aggressive behavior and decreased affiliative behavior in adult male monkeys
after long-term consumption of diets rich in soy protein and isoflavones,” — Simon NG, Kaplan JR, Hu S, and others, Horm Behav. 2004 Apr;45(4):278-84., Department of
Biological Sciences,
; i ; —
Estrogen produced by aromatization of gonadal androgen has an important
facilitative role in male-typical aggressive behavior that is mediated through
its interaction with estrogen receptors (ER) in the brain.
— Isoflavones found in soybeans
and soy-based dietary supplements bind ER and have dose- and tissue-dependent
effects on estrogen-mediated responses. Yet, effects of isoflavone-rich diets
on social and aggressive behavior have not been studied.
— We studied the effects of long-term (15 months) consumption of
diets rich in soy isoflavones on spontaneous social behavior among adult male
cynomolgus macaques (Macaca fascicularis) (n = 44) living in nine stable social
groups.
— There were three
experimental conditions which differed only by the source of dietary protein:
casein and lactalbumin (no isoflavones), soy protein isolate containing 0.94 mg
isoflavones/g protein, and soy protein isolate containing 1.88 mg isoflavones/g
protein.
— In the monkeys fed the higher amount of isoflavones, frequencies
of intense aggressive (67% higher) and submissive (203% higher) behavior were
elevated relative to monkeys fed the control diet (P's < 0.05). In addition, the proportion of time spent
by these monkeys in physical contact with other monkeys was reduced by 68%,
time spent in proximity to other monkeys was reduced 50%, and time spent alone
was increased 30% (P's < 0.02). There were no effects of treatment on serum
testosterone or estradiol concentrations or the response of plasma testosterone
to exogenous gonadotropin-releasing hormone (GnRH).
— The results indicate that ... long-term consumption of a diet rich in
soy isoflavones can have marked influences on patterns of aggressive and social
behavior.
... / 61
- 61 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
n
i i i , i i i , i i i , i i i , (+) i i i - Infants fed soy formula
had prolonged increase of TSH when compared to
infants fed non-soy
formula.
These infants need close monitoring of free thyroxine and TSH
measurements, and they may need increased levothyroxine doses to achieve normal
thyroid function tests.
2004 “Soy formula
complicates management of congenital hypothyroidism,” — S.C. Conrad, H. Chiu and B.L. Silverman, Archives of Disease in Childhood 2004;89:37-40, Department of Pediatrics,
Northwestern University Medical School, Chicago, IL, USA, sconrad@mail.cho.org
— Aims: To test the hypothesis that feeding soy
formula to infants with congenital hypothyroidism (CH) leads to prolonged
increase of thyroid stimulating hormone (TSH).
— Methods: The study was a review of 78 patients
seen during their first year of life between 1990 and 1998. Data regarding
clinical diagnosis, date of treatment initiation, TSH, levothyroxine dose,
weight, length, and diet information from each visit were collected from the
charts.
— Results: There were eight patients in the soy diet
group and 70 in the non-soy diet group. There was no significant difference
between the two groups in the starting dose of levothyroxine or the change in
this dose over one year. There was a significant difference between
the two groups in the following areas: time to TSH normalisation, first TSH on treatment, percentage with
increased TSH at 4 months of age, percentage with increased TSH throughout the
first year of life, and
second, in the overall trend of TSH at each visit.
— Conclusions ... Infants
fed soy formula had prolonged increase of TSH when compared to infants fed
non-soy formula. These infants need close monitoring of free thyroxine and TSH
measurements, and they may need increased levothyroxine doses to achieve normal
thyroid function tests.
i i i , i i i , i i i , i i i , i i i - Further evidence from current
research that beta-Sitosterol,
a
compound common
in soy oil, and also present in soy
protein, can stimulate the growth of
MCF-7 breast cancer cells"
2004 “beta-Sitosterol,
beta-Sitosterol Glucoside, and a Mixture of beta-Sitosterol and beta-Sitosterol
Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In
Vitro and in Ovariectomized Athymic Mice,” — Ju YH, Clausen LM, Allred KF, and others, J Nutr. 2004 May;134(5):1145-1151., Department of Food
Science and Human Nutrition and Department of Animal Sciences, University of
Illinois at Urbana-Champaign, Urbana, IL 61801 USA; and the Department
of Physiology, University of Kentucky, Lexington, KY 40536; and the
IMAGINutrition and MetaResponse Science, Laguna Niguel, CA 92677.
— We hypothesized that the phytosterols
beta-sitosterol (BSS), beta-sitosterol glucoside (BSSG),
and Moducare (MC; BSS:BSSG = 99:1) could modulate the growth of
estrogen-dependent human breast cancer cells in vitro and in vivo ...
— Dietary BSS, BSSG, and MC reduced E(2) -
induced MCF-7 tumor growth by 38.9% (P < 0.05),
31.6% (P = 0.08), and 42.13% (P < 0.05), respectively ...
; i ; —
In summary ... BSS and MC stimulated MCF-7 cell growth in vitro. Although BSSG comprises only 1% of MC, BSSG
made MC less estrogenic than BSS alone in vitro. However, dietary BSS and MC
protected against E(2) - stimulated MCF-7 tumor
growth and lowered circulating E(2) levels.
... / 62
- 62 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
n
i i i , i i i , i i i , i i i - Genistein produced
higher percentage of proliferative cells in tumors,
- Genistein can stimulate the growth of a mammary carcinogen MNU-induced estrogen-dependent mammary tumors.
- Plasma genistein concentrations in animals fed the
isoflavone-containing diet were at
physiological levels relevant to human exposure.
2004 “Dietary
genistein results in larger MNU-induced, estrogen-dependent mammary tumors
following ovariectomy of Sprague-Dawley rats,” — Allred C.D., Allred K.F., Ju Y.H.,
and others,
Carcinogenesis. 2004 Feb;25(2):211-8. Epub 2003 Oct 24., Department of Food Science
and Human Nutrition,
— Due to the estrogenic properties
of soy-derived isoflavones, many postmenopausal women are using these compounds
as a natural alternative to hormone replacement therapy (HRT).
— Genistein at 750 p.p.m. increased the weight of
estrogen-dependent adenocarcinomas in ovariectomized rats compared with the negative-control animals.
— Genistein treatment also resulted in a
higher percentage of proliferative cells in tumors and increased uterine weights when compared
with negative-control animals.
— Collectively, these effects are probably due to the
estrogenic activity of genistein.
— Plasma genistein concentrations in animals fed the
isoflavone-containing diet were at
physiological levels relevant to human exposure. Estradiol
concentrations in
ovariectomized animals not receiving an estradiol supplement were similar to
those observed in postmenopausal women.
; i ; — The data suggest that in an endogenous estrogen environment
similar to that of a postmenopausal woman, dietary genistein can stimulate the growth of a mammary carcinogen MNU-induced estrogen-dependent
mammary tumors.
... / 63
- 63 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“Frying
The Brain With Soy”
(Subsection)
First 2 abstracts on this page, and
the next 4 pages, demonstrate
Soy’s real hazards to the Brain and Nervous system from
“placenta transfer to the foetal brain of
the fetus in the womb” ... to the newly born baby ... into childhood, even on
to
late adulthood, (Also see thyroid problems). Soy’s connection to “Alzheimer’s and
Parkinson’s Disease, M.S., and
ADD / ADHD”
is because genistein in Soy damages the “Myelin Sheath”
that surrounds the nerves, spinal cord
and brain tissue, and it also lowers
cholesterol ... (The danger is that Soy can & does lower
cholesterol, but
to far for the proper development and
“SUSTAINED” health of the myelin sheath), pages 64 – 67.
Also see pagers 6, 7, 10, 20(m.), 20(n.), 92,
113, 121.
; i ;
i i i , i i i , i i i , i i i - significant reductions were found in brain-derived neurotrophic
factor
(BDNF) mRNA expression in the CA3 and CA4 region of
the hippocampus and in the cerebral cortex in
the rats fed the diet containing phytoestrogens,
compared with those on the soya-free diet.
2003 “Soya
phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male
rats,” – File SE, Hartley DE, Alom N., Neurosci Lett 2003 Feb 27;338(2):135-38., Psychopharmacology Research Unit and
Biochemical Neuropharmacology Group, Centre for Neuroscience Research, King's
College London, Hodgkin Building, Guy's Campus, SE1 1UL, London, UK.
; i ; —
Adult male hooded Lister rats were either fed a diet containing 150 microg/g
soya phytoestrogens or a
soya-free diet for 18 days. This concentration of phytoestrogens should
have been sufficient to occupy the oestrogen-beta, but not the oestrogen-alpha,
receptors. Using in situ hybridisation, significant reductions were found in brain-derived
neurotrophic factor (BDNF) mRNA expression in the CA3 and CA4 region of the hippocampus
and in the cerebral cortex in the rats fed the diet containing phytoestrogens,
compared with those on the soya-free diet. No changes in
glutamic acid decarboxylase-67 or glial fibrillary acidic protein mRNA were
found. This suggests a role for
oestrogen-beta receptors in regulating BDNF mRNA expression.
i i i , i i i , i i i , i i i - BDNF mRNA is reduced in the human Alzheimer's disease
hippocampus
and temporal cortex, and suggest that a loss of BDNF may contribute to the
progressive atrophy of neurons in Alzheimer's
disease.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9387865&dopt=Abstract
.
1997 “Brain-derived
neurotrophic factor is reduced in Alzheimer's disease,” – Connor B, Young D, Yan Q, and others., Brain Res Mol Brain Res., 1997 Oct3;49(1-2):71-81.,
Department of Pharmacology, Faculty of Medicine and Health Science, University
of Auckland, New Zealand.
; i ; — Alzheimer's disease may be due to a
deficiency in neurotrophin protein or receptor expression. Consistent with
this hypothesis, a reduction in BDNF mRNA expression has
been observed in human post-mortem Alzheimer's disease hippocampi. To
further investigate this observation, we examined whether the alteration in
BDNF expression also occurred at the protein level in human post-mortem
Alzheimer's disease hippocampi and temporal cortices using immunohistochemical
techniques. We observed a reduction in
the intensity and number of BDNF-immunoreactive cell bodies within both the
Alzheimer's disease hippocampus and temporal cortex when compared to normal
tissue. These results support and
extend previous findings that BDNF mRNA is reduced in the human Alzheimer's disease
hippocampus and temporal cortex, and suggest that a loss of BDNF may contribute to the progressive
atrophy of neurons in Alzheimer's disease.
Note: Make sure the label on your vitamins, minerals, and
medications says … contains no Soy
… or … contains no Soy ingredients .
Pet Food, farm animal foods
... / 64
- 64 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Frying The Brain With Soy
...
continued ...
i i i , i i i , i i i , i i i - Poor cognitive
test performance ... low brain weight ... brain atrophy.
2000 “Brain aging
and midlife tofu consumption,” – White
L.R., Petrovitch H., Ross G.W., and others, J Am Coll Nutr. 2000 Apr;19(2):242-55., National Institute on
Aging,
; i ; —
RESULTS: Poor
cognitive test performance... enlargement of ventricles... low brain weight... were each significantly &
independently associated with higher mid-life tofu consumption.
— A similar association of
midlife tofu intake with poor late life cognitive test scores was also observed among wives of cohort members, using the husbands answers to food
frequency questions as proxy for the wife’s consumption.
— Statistically significant
associations were consistently demonstrated in linear and logistic multivariate
regression models.
— CONCLUSIONS: In
this population, higher midlife tofu consumption was independently associated
with indicators of cognitive impairment and brain atrophy in late life.
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
- Soya
content of diet can have significant effects on brain
and behaviour
2003 “The soya
isoflavone content of rat diet can increase anxiety and stress hormone release
in the male rat,” – Hartley D.E.,
Edwards J.E., & others, Psychopharmacology
(Berl) 2003 Apr, 167(1):46-53., Epub Mar 05
. Psychopharmacology Research Unit,
Centre for Neuroscience, Hodgkin Building, Kings College London, Guy's Campus,
SE1 1UL, London, UK. david.2.hartley@kcl.ac.uk
.
— RATIONALE: Most commercial
rodent diets are formulated with soya protein and therefore contain soya isoflavones. Isoflavones form one of the
main classes of phytoestrogens and have been found to exert both oestrogenic
and anti-oestrogenic effects on the central nervous system. The effects have
not been limited to reproductive behaviour, but include effects on learning and
anxiety and actions on the hypothalamo-pituitary axis. It
is therefore possible that the soya content of diet could have significant
effects on brain and behaviour and be an
important source of between-laboratory variability.
— OBJECTIVES: To
determine whether behaviour in two animal tests of anxiety, and stress hormone
production, would differ between rats that were fed a diet which was free of
soya isoflavones and other phytoestrogens (iso-free) and those that were fed a
diet which contained 150 &mgr;g/g of the isoflavones genistein and daidzein
(iso-150). This controlled diet has an isoflavone concentration similar to that
in the maintenance diet routinely used in our institution.
— METHODS: Male rats were randomly allocated to the
iso-free and iso-150 diets and their body weights and food and water
consumption were recorded for 14 days. They were then maintained on the same
diets, but housed singly for 4 days, before testing in the social interaction
and elevated plus-maze tests of anxiety. Corticosterone concentrations in both
dietary groups were determined under basal conditions and after the stress of
the two tests of anxiety. Vasopressin and oxytocin concentrations were
determined after brief handling stress.
— RESULTS:. The groups did not differ in food or
water intake, body weight or oxytocin concentrations. Compared with the rats
fed the iso-free diet, the rats fed the iso-150 diet spent
significantly less time in active social interaction and made a significantly
lower percentage of entries onto the open arms of the plus-maze, indicating
anxiogenic effects in both animal tests. The groups did not differ in their basal corticosterone
concentrations, but the iso-150 group had significantly elevated stress-induced
corticosterone concentrations. Stress-induced
plasma vasopressin concentrations were also significantly elevated in the
iso-150 diet group compared with the iso-free rats.
— CONCLUSIONS:. Major changes in behavioural measures of
anxiety and in stress hormones can result from the soya isoflavone content of
rat diet. These changes are as striking as those seen following drug
administration and could form an important source of variation between
laboratories.
... / 65
- 65 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Frying The Brain With Soy
PubMed Abstracts - Short List
...
continued ...
------ Original Message -----
From: Gerald
Hernesmaa
To: Valerie
& Richard James ... Soy Online Service , S.O.S.,
New Zealand
Sent:
Subject: Any abstracts linking
Soy to Parkinson's Disease (Manganese poisoning)
Reply
...
From: Valerie
& Richard James , Soy Online
Service
Sent:
Hi
Gerald. Not that we
know of. No specific research has
been done linking the two. David Goodman makes a very good
circumstantial
case for manganese causation. We are
also convinced that genistein,
being a tryrosine kinase inhibitor, could also cause it and other
motor neurone diseases. Best regards, Dick
Reply
...
From: Valerie
& Richard James , Soy Online
Service
Sent:
When
I get time, maybe
tomorrow, I'll search in PubMed for “myelinisation” etc.
Genistein is reported
to destroy the myelin that
protects the nerves...leading to what is
very like “Parkinson’s.” Dick
Reply
...
From: Valerie
& Richard James , Soy Online
Service
Sent:
Subject: LOOKING THROUGH PUBMED AT MYELIN
Hi
Gerald, What turns up
time after time in rat and mice studies is that Soy lowers cholesterol. Cholesterol is necessary for
development
of myelin
to sheath the nerves. It could lead to Parkinson’s and other neurologic diseases. It
sure is a bad idea to feed it to babies.
Dick
................%%%......%%%......%%%......%%%......%%%......%%%......%%%......%%%..................
Results of S.O.S.
search in PubMed
; i ;
i i i , i i i , i i i , i i i , (+) i i i -
#
23. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2868833&dopt=Abstract
.
1986 “Effects of
postnatal protein undernutrition on myelination in rat brain,” – Egwin P.O., Cho B.H., Kummerow F.A., Comp Biochem Physiol A. 1986;83(1):67-70., Egwim
; i ; — Damages the myelin to sheath around the nerves.
— “A more pronounced
retardation” in the initiation, progression and capacity of myelination
in postnatal “Soy Protein under-nutrition was indicated.”
—
Pups were subjected, from birth, to - protein under-nutrition
by feeding the lactating dams 8% casein (CS) or - 8% Soy Protein (SP) diet - up to
weaning; the weanlings were fed the same diets until 6 weeks of age. At 3 and 6
weeks of age, myelin was isolated from the brains
and characterized. The quantities of myelin and its content of
cholesterol, galactolipids and phospholipids, were significantly depressed in
the 8% CS and 8% SP groups but not when soy protein was fed at the same level
as casein (25%) in the control. Furthermore, the severity of the deficits in
myelination showed a differential pattern depending on the type of dietary
protein fed. At weaning, the deficits with the 8% SP diet were 1.5-2.0-times
greater than with the corresponding casein diet.
— “A more pronounced
retardation” in the initiation, progression and capacity of myelination
in postnatal “Soy Protein under-nutrition was indicated.” ... / 66
- 66 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Frying The Brain With Soy
PubMed Abstracts - in Short List
...
continued ...
i i i , i i i , i i i , i i i , (+) i i i -
#
24. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7241137&dopt=Abstract
.
1981 “Effects of
altered thyroid states on myelinogenesis,” – Walters S.N., Morell P., J Neurochem. 1981 May,35(5):1792-801.
— Myelinogenesis was studied in controls and in rats treated since
birth with Methimazole (hypothyroid) or thyroxine (hyperthyroid). The amount of myelin in forebrain and its
protein composition were determined between 13 and 40 days of age, the period
of most rapid myelin accumulation. Hypothyroid rats had reduced on both and
brain weights relative to controls and the yield of myelin was reduced on both
a per brain and a per milligram brain protein basis. Developmental changes in
the protein composition of isolated myelin followed the pattern of control
animals (the percentage of total myelin protein present as proteolipid protein,
large basic protein, and small basic protein increased, as did the ratio of
proteolipid/large basic protein) but were delayed temporally by 1-2 days.
Hyperthyroid rats also had reduced body and brain weights. At 13 days myelin
accumulation was greater than that of controls, corresponding to an earlier
initiation of myelination. At later ages myelin yield was reduced on a per
brain basis but not on a per milligram brain protein basis. The developmental
pattern of myelin protein composition was accelerated temporally by 1-2 days.
Myelination in optic nerve, assayed by proteolipid protein content, also was
slightly delayed in hypothyroid animals and somewhat accelerated in
hyperthyroid animals. The relative synthesis of myelin proteins (determined as
incorporation of intracranially injected [(3)H]glycine into myelin protein
relative to incorporation into whole brain protein), as well as distribution of
radioactivity among individual myelin proteins, was determined.
— THE RESULTS supported the conclusion of the myelin protein accumulation
study; hypo-thyroidism retards the developmental program for myelinogenesis, whereas in
the hyper-thyroid state myelin synthesis is initiated earlier but is also terminated
earlier.
i i i , i i i , i i i , i i i , (+) i i i -
#
25. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=2432794&dopt=Abstract
.
1986 “Effect of
prenatal iron deficiency on myelination in rat pups,” – Yu G.S., Steinkirchner T.M. and others., Am J Pathol 1986 Dec; 125(3):620-4.
— In this study, a histopathologic examination of the brain from iron-deficient or iron-supplemented
rat pups was carried out.
Pups were obtained from female rats, which were fed an iron-deficient or
iron-supplemented diet during both pregnancy and lactation. Immediately after
anesthesia and the collection of blood, pups were fixed by intracardiac
infusion of 2% glutaraldehyde. Brain and cervical spinal cord were fixed,
embedded in paraffin, and cut at 6-mu thickness. Myelin was identified
using Luxol fast blue stain. As compared with controls (hematocrit, 30.8%), 11-day-old
iron-deficient pups (hematocrit, 11.9%) showed reduced myelination in the
spinal cord.
— Although myelination increased somewhat in the iron-deficient
17-day-old pups (hematocrit, 8.5%), the amount of “myelin”
in the spinal cord and white matter of cerebellar folds “was reduced” as
compared with that of the corresponding controls.
; i ; —
THESE OBSERVATIONS SHOW the importance of prenatal iron adequacy in
myelinogenesis.
— ( The unborn child also gets what the mother eats. Here is another good reason to avoid Soy
in pregnancy.)
................%%%......%%%......%%%......%%%......%%%......%%%......%%%......%%%..................
“Coconut Oil and
Coconut Milk - General Discussion”
DC Nutrition - Health and Well-being
http://www.dcnutrition.com/miscellaneous/Detail.CFM?RecordNumber=569
. Good information in the paragraph below, but can not find
1978
and 1980 abstracts in
PubMed as references, probably not entered into the system yet, need to go
directly to the original medical research library or medical text book.
"... Brain tissue is very rich in complex forms of fats.
The experiment (around 1978) in which pregnant mice were given diets containing either
coconut oil or unsaturated oil showed that brain development was superior in
the young mice whose mothers ate coconut oil.
Because coconut oil supports thyroid function, and thyroid governs brain
development, including myelination ( the insulation
around the nerves ), the
result might simply reflect the difference between normal and hypothyroid
individuals. However,
in 1980, experimenters demonstrated
that young rats fed milk containing soy oil incorporated the oil directly
into their brain cells, and had structurally
abnormal cells
as a result ...". ... / 67
- 67 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Frying The Brain With Soy
PubMed Abstracts - Short List
...
continued ...
i i i , i i i , i i i , i i i , (+) i i i - The highest
concentrations of daidzein and genistein were detected in
a
soy-based powdered infant formula.
2004 “Trace
determination of bisphenol A and phytoestrogens in infant formula powders
by gas chromatography-mass spectrometry,” — Kuo
HW, Ding WH.,
J Chromatogr A. 2004 Feb 20;1027(1-2):67-74., Department of Chemistry,
— This investigation describes
a reliable and sensitive method for simultaneously determining bisphenol A
(BPA) and two major
phytoestrogens, daidzein and genistein, in powdered milks and infant formulas by gas chromatography-mass spectrometric
analysis after trimethylsilylation.
— To reduce the matrix
interference associated with the constituents of the formulas, the dissolved
formula solutions were firstly ultra-centrifuged and the analytes in the
supernatant were then extracted using a C18 solid-phase extraction column. The
accuracy and precision of the method were determined and the technique was
successfully employed to measure trace concentrations of BPA, daidzein and
genistein in powdered formulas.
— The results show that BPA,
daidzein and genistein were detected in all the testing samples
(n = 6) at concentrations from 45 to 113 ng/g (except one infant formula), 20 to 2050 ng/g and 21 to 6510 ng/g,
respectively.
; i ; — The highest concentrations of
daidzein and genistein (i.e., 2050 and 6510 ng/g) were detected in a soy-based
powdered infant formula. The quantitation limits were 1.0 ng/g for
BPA, and 10 ng/g for daidzein and genistein
using 0.5 g powdered milk samples.
i i i , i i i , i i i , i i i , (+) i i i - Dietitians should
discourage the use of soya protein in children with atopy
or cow's milk allergy in the first six months
2003 “Paediatric
group position statement on the use of soya protein for infants,” — The British Dietetic Association, J Fam Health Care. 2003;13(4):93.
— Breast feeding should be
strongly encouraged as providing the safest, most nutritionally adequate form
of feeding for most infants. Dietitians should discourage the use of
soya protein in children
with atopy or cow's milk allergy in the first six months of life to avoid
sensitisation to soya protein and exposure to phytoestrogens while organ
systems remain at their most vulnerable. This
would include soy infant formula and soya products such as desserts etc.
When a soy-based infant formula is used, parents
should be informed of current findings relating to phytoestrogens
and health and on the clinical need for soy formula. Any parent choosing to refuse soya for their infant should be supported
in their decision. More
research into the long-term effects of phytoestrogen exposure in infants is
needed and into whether any adverse effects are dose related. This position
statement will be updated as further evidence becomes available.
... / 68
- 68 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i , (+) i i i - http://www.soyonlineservice.co.nz/07abstract.htm
.
2003 “Review Article
– Soy infant formula and phytoestrogens,” — P.G.
Tuohy,
Journal of Paediatrics and Child Health; August 2003, Volume 39 Issue 6, Page
401-5
— Soy infant formula
contains high levels of the isoflavones, genistein and daidzein, which are
commonly referred to as phytoestrogens. These are non-steroidal
chemicals with structural similarities to estrogen. Infants consuming soy formula have high levels of circulating
isoflavones.
; i ; —
These are an order of magnitude greater than the levels of isoflavones which
have been shown to produce physiological effects in adult women consuming a
high soy diet. There is conflicting evidence about the risks
and benefits of soy phytoestrogens, with research presenting a contradictory
picture. Some reviewers suggest that early exposure to soy may prevent cancer
and heart disease. However, there is
very little research on the effects of consumption of soy phytoestrogens by
human neonates. Against this generally
positive view there is an increasing number
of recent reports that suggest that in experimental animals, phytoestrogens
have ... adverse effects with respect to ... carcinogenesis ... reproductive
function ... immune function ... and thyroid disease.
— Despite the absence of adequate scientific research that
quantifies the level of risk to infants, most would argue for a “Precautionary
Approach” to be taken in situations where there are
potential developmental effects from the consumption of pharmacologically
active compounds in infancy and childhood.
i i i , i i i , i i i - The incidence of
positive thyroid antibodies was two and one half times higher
in
formula-fed diabetic children than in breast-fed ones.
- http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3155358
.
1986 “Breast feeding
and insulin-dependent diabetes mellitus in children,” –
— We have evaluated the
hypothesis of a protective effect of human milk on the development of insulin
dependent diabetes mellitus (IDDM). We studied the feeding histories of 95
diabetic children and compared them with controls consisting of their
non-diabetic siblings and a pair matched group of nondiabetic peers of the same
age, sex, geographical location, and social background. The incidence of breast
feeding in diabetic children was 18%. This was similar to the control group.
The duration of breast feedings was also similar among all three groups. There
was no difference in the age of introduction of solid food between diabetic and
nondiabetic children. Twice as many diabetic children, however,
received soy containing formula in infancy as compared to control children. The mean age of onset of IDDM was not
related to the type of feeding during infancy. The incidence of positive
thyroid antibodies was two and one half times higher in formula-fed diabetic
children than in breast-fed ones. In our studies we were unable to document any relationship between
the history of breast feeding and subsequent development of IDDM in children.
... / 69
- 69 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - soy formula, preterm
infant formula, and formulas for specifics disorders
are heavily contaminated with Aluminum.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3292633&dopt=Abstract
.
1988 “Aluminum and
bone disorders: with specific reference to aluminum contamination of infant
nutrients,” – Koo W.W., Kaplan
; i ; —
Aluminum (Al) impairment of
bone matrix formation and mineralization may be mediated by its direct effect
on bone cells or indirectly by its effect on parathyroid hormone and calcium
metabolism. Its toxic effects are proportional to tissue Al load. Al
contamination of nutrients depends on the amount of Al present naturally in
chemicals or from the manufacturing process. Intravenous calcium, phosphorus,
and albumin solutions have high Al (greater than 500 micrograms/L), whereas
crystalline amino acid, sterile water, and dextrose water have low Al (less
than 50 micrograms/L) content.
— Enteral nutrients including human and whole cow milk have low Al,
whereas highly processed infant formulas with multiple additives, such as soy
formula, preterm infant formula, and formulas for specific disorders are
heavily contaminated with Al. Healthy adults are in zero balance for Al. The gastrointestinal
tract excludes greater than 95% of dietary Al, and kidney is the
dominant organ for Al excretion.
— However, even with normal renal function, only 30-60% of an Al
load from parenteral nutrition is excreted in the urine, resulting in tissue
accumulation of Al. The
risk for Al toxicity is greatest in infants with chronic renal insufficiency,
recipients of long term parenteral nutrition, i.e., no gut barrier to Al
loading, and preterm infants with low Al binding capacity. The rapid growth of
the infant would theoretically potentiate Al toxicity in all infants, although
the critical level of Al loading causing bone disorders is not known.
— To minimize tissue burden ... Al content of infant nutrients should be
similar to "background" levels, i.e., similar to whole milk (less
than 50 micrograms/L).
i i i , i i i , i i i - the frequency of feedings with
soy-based milk formulas in early life was significantly higher
in
children with autoimmune thyroid disease.
; i ;
- http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2338464
.
1990 “Breast and
soy-formula feedings in early infancy and the prevalence of autoimmune thyroid
disease in children,” – Fort P., Moses
N., Fasano M., and others., Department of Pediatrics,
North Shore University Hospital-Cornell University Medical College, Manhasset,
New York 11030. Am Coll Nutr 1990 Apr;9(2):164-7.
— It has been suggested that
feeding practices in infancy may affect the development of various autoimmune
diseases later in life.
— Since thyroid alterations are among the most frequently
encountered autoimmune conditions in children, we studied whether breast and
soy-containing formula feedings in early life were associated with the
subsequent development of autoimmune thyroid disease. A detailed history of feeding practices
was obtained in 59 children with autoimmune thyroid disease, their 76 healthy
siblings, and 54 healthy nonrelated control children. There was no difference
in the frequency and duration of breast feeding in early life among the three
groups of children.
— However, the frequency of
feedings with soy-based milk formulas
in early life was significantly higher in children with autoimmune
thyroid disease (prevalence
31%) as compared with their siblings (prevalence 12%; chi 2 = 7.22 with
continuity factor; p less than 0.01), and healthy nonrelated control children
(prevalence 13%, chi 2 = 5.03 with continuity factor; p less than 0.02).
; i ; —
Therefore,
this retrospective analysis documents the association
of “soy formula feedings in infancy” and autoimmune thyroid
disease.
... / 70
- 70 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - DNA fragmentation and cell DEATH,
- http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8242767&dopt=Abstract
.
1993 “Induction of
mouse thymocyte apoptosis by inhibitors of tyrosine kinases is associated with
dephosphorylation of nuclear proteins,” – Azuma
Y., Onishi Y., Sato Y., Kizaki H., Cell Immunol 1993 Nov 152:(1) 271-8., Department of Biochemistry, Tokyo
Dental College, Chiba, Japan.
— DNA fragmentation and cell DEATH
; i ; —
Incubation of mouse thymocytes with the protein tyrosine kinase inhibitors
herbimycin A and methyl-2,5-dihydroxycinnamate induced a decreased and altered
profile of nuclear phosphotyrosine proteins in parallel with an increase in
internucleosomal DNA fragmentation and cell death dose-dependently.
— No change in the profile of cytoplasmic phosphotyrosine proteins
was observed. DNA fragmentation was dependent on the synthesis of RNA and
protein, suggesting that the inhibition of tyrosine phosphorylation of the
nuclear proteins induces apoptosis.
— DNA fragmentation was enhanced by simultaneous incubation
with phorbol esters capable of activating protein kinase C.
— Genistein, another inhibitor of protein tyrosine kinase, induced
DNA fragmentation more rapidly
than herbimycin A, but there was no predominant alteration of
phosphotyrosine proteins in early incubation, suggesting that genistein
may induce apoptosis by a mechanism other than direct inhibition
of protein tyrosinekinase activity.
i i i , i i i , i i i , i i i - DNA strand breaks, - http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7892284&dopt=Abstract
.
1995 “Genistein as
an inducer of tumor cell differentiation: possible mechanisms of action,” – Constantinou A., Herberman E., Proc
Soc Exp Biol Med. 1995 Jan 208: 1 109-15.
— Decreased activity of either
topoisomerases or tyrosine kinases has been implicated in the differentiation
of a number of cell types. It is therefore conceivable that genistein, because
of its reported ability to inhibit these activities in vitro, may be an inducer
of cellular differentiation. We investigated this possibility in human
promyelocytic HL-60 and erythroid K-562 leukemia cells and in human SK-MEL-131
melanoma cells. Our results indicated that genistein, in a dose-dependent
manner, inhibited cell multiplication and induced cell differentiation. The maturing HL-60 cells acquired
granulocytic and monocytic markers. The differentiating K-562 cells stained
positively with benzidine, which indicates the production of hemoglobin, an
erythroid marker. Following genistein treatment, maturing SK-MEL-131 melanoma
cells formed dendrite-like structures and exhibited increased tyrosinase
activity and melanin content. Experiments were designed to identify the
molecular mechanism of genistein's action.
--- Data
from our laboratory suggest that this isoflavone triggers the pathway that
leads to cellular differentiation by stabilizing protein-linked DNA strand
breakage. Other possible mechanisms reported in the literature are
discussed.
... / 71
- 71 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - high-temperature wok cooking with unrefined
Chinese rapeseed oil may
increase
Lung cancer risk ... Canola
... Soy.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7791233&dopt=Abstract .
1995 “Mutagens from
heated Chinese and U.S. cooking oils,” – Shields
P.G., Xu G.X., Blot W.J., and others, J Natl Cancer Inst 1995 Jun 7;87(11):836-41, Laboratory of Human
Carcinogenesis, National Cancer Institute, Bethesda, Md 20892, USA.
— BACKGROUND: The lung cancer incidence in Chinese women
is among the highest in the world, but tobacco smoking accounts for only a
minority of the cancers. Epidemiologic investigations of lung cancer among
Chinese women have implicated exposure to indoor air pollution from wok
cooking, where the volatile emissions from unrefined cooking oils are
mutagenic.
— PURPOSE: This study was conducted to identify and
quantify the potentially mutagenic substances emitted from a variety of cooking
oils heated to the temperatures typically used in wok cooking.
— RESULTS:
1,3-Butadiene ... benzene ... acrolein ... formaldehyde ... and other related
compounds were qualitatively and quantitatively detected, with emissions
tending to be highest for unrefined Chinese rapeseed oil and lowest for peanut
oil. The emission of
1,3-butadiene and benzene was approximately 22-fold and 12-fold higher,
respectively, from heated unrefined Chinese rapeseed oil than from heated
peanut oil. Lowering the cooking temperatures or adding an antioxidant, such as
butylated hydroxyanisole, before cooking decreased the amount of these volatile
emissions. Among the individual fatty acids tested, heated linolenic acid
produced the greatest quantities of 1,3-butadiene, benzene, and acrolein.
Separately, the mutagenicity of individual volatile emission condensates was
correlated with linolenic acid content (r = .83; P = .0004). Condensates from
heated linolenic acid, but not linoleic or erucic acid, were highly mutagenic.
; i ; — CONCLUSIONS: These studies, combined with experimental
and epidemiologic findings, suggest that high-temperature wok cooking with
unrefined Chinese rapeseed oil may increase lung cancer risk. This study indicates methods that may
reduce that risk.
— IMPLICATIONS: The common use of wok cooking in
Mmm
i i i , i i i , i i i , i i i - DNA damage … http://www.soyonlineservice.co.nz/04immunefunction.htm
.
- Genistein has been previously reported to stabilize
the covalent topo II-DNA cleavage complex and thus function as a “topo II poison”.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7769390&dopt=Abstract
.
1995 “Flavonoids as
DNA topoisomerase antagonists and poisons: structure-activity relationships,” –
Constantinou A., Mehta R. and others,
J Nat Prod 1995 Feb 58:2 217-25.
— Selected flavonoids were
tested for their ability to inhibit the catalytic activity of DNA topoisomerase (topo) I and II. Myricetin,
quercetin, fisetin, and morin were found to inhibit both enzymes, while
phloretin, kaempferol, and 4',6,7-trihydroxyisoflavone inhibited topo II
without inhibiting topo I. Flavonoids demonstrating potent topo I and II
inhibition required hydroxyl group substitution at the C-3, C-7, C-3', and C-4'
positions and also required a keto group at C-4. Additional B-ring
hydroxylation enhanced flavonoid topo I inhibitory action. A C-2, C-3 double
bond was also required, but when the A ring is opened, the requirement for the
double bond was eliminated.
; i ; —
Genistein has been previously reported to stabilize the covalent topo
II-DNA cleavage complex and thus function as a topo II
poison. All flavonoids were tested for their
ability to stabilize the cleavage complex between topo I or topo II and DNA.
None of the agents stabilized the topo I-DNA cleavage complex, but prunetin,
quercetin, kaempferol, and apigenin stabilized the topo II DNA-complex.
— Competition experiments have
shown that genistein-induced topo II-mediated DNA cleavage can be inhibited by myricetin,
suggesting that both types of inhibitors (antagonists and poisons) interact
with the same functional domain of their target enzyme. These results are of
use for the selection of flavonoids that can inhibit specific topoisomerases at
specific stages of the topoisomerization reaction.
... / 72
- 72 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - DNA strand breaks
- http://www.soyonlineservice.co.nz/04immunefunction.htm
.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9225019&dopt=Abstract
.
1996 “Induction of
micronuclei, DNA strand breaks and HPRT
mutations in cultured Chinese hamster V79 cells by the phytoestrogen
coumoestrol,” – Kulling S.E., Metzler
M., Food
Chem Toxicol 1996, 35:605-13.
— Coumoestrol (COUM),
genistein (GEN) and daidzein (DAI) are major phytoestrogens present in numerous
plants eaten by humans and food-producing animals. Little is known about the
genotoxicity of these natural compounds.
— The effects of COUM, GEN and
DAI were studied in cultured Chinese hamster V79 cells at various endpoints.
None of the substances affected the cytoplasmic microtubule complex or the
mitotic spindle.
; i ; —
However, COUM and GEN but not DAI proved to be strong inducers of DNA
strand breaks and micronuclei containing acentric fragments, as shown with antikinetochore
antibodies. The clastogenicity of GEN may be due to its non-intercalative
inhibitory effect on topoisomerase II, whereas COUM may act through
topoisomerase II inhibition and/or DNA intercalation.
— COUM was also a clear
inducer of hypoxanthine guanine phosphoribosyltransferase (HPRT) mutations in
V79 cells; GEN was only marginally active and DAI inactive at this endpoint.
This is the first report in the clastogenicity and mutagenicity of COUM in
mammalian cells.
i i i , i i i , i i i , i i i - Hypocalcemia-hyperphosphatemia
... life-threatening hypocalcemic
hyperphosphatemic
spasms in the infant
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9064373
.
1996 “Hypocalcemic
tetany in 'alternative' soy milk nutrition in the first months of life,” – Anil M, Demirakca S, Dotsch J, Kiess W., Klin Padiatr. 1996 Nov-Dec;208(6):323-6., Abteilung
Allgemeine Padiatrie und Neonatologie, Justus Liebig Universitat
; i ; Malnutrition ... from ... False Nutritional Beliefs
— A 14 weeks old infant was admitted to the intensive care unit
with life-threatening hypocalcemic-hyperphosphatemic spasms. Hypocalcemia -hyperphosphatemia was
found to have been caused by feeding a high phosphate/ low calcium soy
milk. The daily uptake of
calcium was calculated to have been 3.3-6 mmol that of phosphate 30 mmol.
— The parents strongly believed
that soy milk formulas were equivalent to breast milk and cow's milk formulas
and lived on a strictly vegetarian diet. Therapy with calcium (at
an initial dose of 2.25 mmol/kg/day) and 1.25 OH vitamin D3 (Rocaltrol, 0.25
microgram/day) normalized Ca, PO4, vitamin D and parathyroid hormone levels
rapidly.
— We conclude:. Vegetarian feeding had led to
life-threatening hypocalcemic - hyperphosphatemic spasms in the infant, as well
as, malnutrition
and false nutritional beliefs
have to be included as a potential cause of early hypocalcemia in infants.
... / 73
- 73 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
n
i i i , i i i , i i i , i i i -
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8932918
.
1996 “Maternal
exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (
— Nearly 80 percent of infant
leukemias present with an abnormality involving the MLL gene at 11q23.
Moreover, secondary acute myeloid leukemias (AML) that occur as the result of
chemotherapy agents, which are known to inhibit DNA topoisomerase II, often
manifest the same MLL abnormalities.
; i ; — It
has been hypothesized that de novo infant leukemias may occur as a result of
maternal exposure to agents in diet and medications that inhibit DNA
topoisomerase II.
— Three epidemiologic studies
of childhood leukemia with similar methodologies were conducted in the
— However, within the AML stratum, there was a statistically significant
positive association (P trend = 0.04) with increasing consumption of DNA
topoisomerase II-inhibitor containing foods (odds ratio [OR] = 9.8, 95 percent
confidence interval [CI] = 1.1-84.8; OR = 10.2, CI = 1.1-96.4; for medium and
high consumption, respectively).
— Results of this
preliminary study, in combination with molecular data, should be used in
future investigations of childhood leukemia (particularly, infant) to justify the incorporation of a
detailed dietary history.
i i i , i i i , i i i , i i i -
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9710315&dopt=Abstract
.
1998 “Xenoestrogens
significantly enhance risk for breast cancer during growth and adolescence,” – Ardies C.M. and Dees C.,
Med Hypotheses 1998 Jun 50:6 457-64., Department of Biological and Exercise
Sciences, Northeastern Illinois University, Chicago 60625-4699, USA.
— Breast cancer is one of the
most common forms of cancer observed in women, and endogenous estrogen is
thought to play a major role in its development. Because of this, any
conditions or exposures which enhance estrogenic responses would result in an
increased risk for breast cancer.
; i ; —
The role of xenoestrogenic compounds, such as DDT, in the etiology of breast cancer is still very controversial. In
the following paper we discuss recently-published observations by ourselves and
others which indicate that xenoestrogens may play a significant role
in the development of breast cancer.
— Specifically, we hypothesize
during periods of high growth rates & during breast development the
sensitivity of breast cells to estrogenic compounds is sufficiently great for
xenoestrogens to significantly enhance risk for breast cancer.
i i i , i i i , i i i , i i i , (+) i i i - Genistein acts as
an estrogen in utero, and may increase the incidence of
mammary tumors if given through a pregnant mother.
1998 “Maternal
genistein exposure mimics the effects of estrogen on mammary gland development
in female mouse offspring,” — Hilakivi-Clarke
L, Cho E.,
Oncol Rep. 1998 May-Jun;5(3):609-16., Lombardi Cancer Center, Research Bldg.,
Room W405, Georgetown University, 3970 Reservoir Road, NW, Washington, DC, USA.
— "Human and animal data indicate that a high maternal
estrogen exposure during pregnancy increases breast cancer risk among
daughters. This may reflect an increase in the
epithelial structures that are the sites for malignant transformation, i.e.,
terminal end buds (TEBs), and a reduction in epithelial differentiation in the
mammary gland. Some phytoestrogens, such
as genistein which is a major component in soy-based foods, and zearalenone, a mycotoxin found in
agricultural products, have estrogenic effects on the reproductive system,
breast and brain.
— These findings indicate that maternal exposure to
physiological doses of genistein
mimics the effects of E2 on the mammary gland and reproductive systems in the
offspring.
; i ; —
Thus, our results suggest that genistein acts as an estrogen in utero,
and may increase the incidence of mammary tumors if given through a pregnant
mother. The estrogenic effects of zearalenone on
the mammary gland, in contrast, are probably counteracted by the permanent
changes in estrus cycling."
... / 74
- 74 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - http://www.soyonlineservice.co.nz/articles/Helf.htm
.
- Also, see next to bottom
page 37, 1997 … proliferation of
cultured human breast cancer cells … Dees concluded that
“… women should not
consume particular foods, (eg. Soy-derived
products), to prevent breast cancer …”.
- Also, see next to bottom
page 40, 1998 …
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9731492
.
1998 “Estrogenic
effects of genistein on the growth of estrogen receptor-positive human breast
cancer (MCF-7) cells in vitro and in vivo,” – Hsieh C.Y., Santell R.C., Haslam S.Z., Helferich W.G., Cancer
Res 1998 Sep 1 58:17 3833-8., Department
of Food Science and Human Nutrition, Michigan State University, East Lansing
48824, USA.
— Genistein, found in soy products, is a phytochemical with several
biological activities. In the current study, our research focused
on the estrogenic and proliferation-inducing activity of genistein.
— We have demonstrated that genistein
enhanced the proliferation of estrogen-dependent human breast cancer (MCF-7)
cells in vitro at
concentrations as low as 10 nM, with a concentration of 100 nM achieving
proliferative effects similar to those of 1 nM estradiol. Expression
of the estrogen-responsive
gene pS2 was also induced in MCF-7 cells in response to treatment with a
concentration of genistein as low as 1 microM. At higher concentrations (above
20 microM), genistein inhibits MCF-7 cell growth. In vivo, we have shown that
dietary treatment with genistein (750 ppm) for 5 days enhanced mammary gland
growth in 28-day-old ovariectomized athymic mice, indicating that genistein acts as an estrogen in normal mammary
tissue. To evaluate whether the estrogenic effects observed in vitro with MCF-7 cells could be reproduced in
vivo, MCF-7 cells were implanted
— Tumors were larger in the
genistein (750 ppm)-treated group than they were in the negative control group, demonstrating that dietary genistein was
able to enhance the growth of MCF-7 cell tumors in vivo. Increased uterine
weights were also observed in the genistein-treated groups.
— In summary, genistein can act as an estrogen agonist in vivo
and in vitro,
resulting in the proliferation of cultured human breast cancer cells (MCF-7)
and the induction of pS2 gene expression. Here we present new
information that dietary genistein stimulates mammary gland growth and
enhances the growth of MCF-7 cell tumors in ovariectomized athymic mice.
See page 37 1997
; i ; ---
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9168007&dopt=Abstract
.
“Dietary estrogens
stimulate human breast cells to enter the cell cycle,” –
--- Dr Craig Dees of Oak Ridge National Laboratory has also found that soy
isoflavones cause breast cancer cells to grow. He reported that “… dietary estrogens at low concentrations,
(genistein), do not act as antiestrogens, but like DDT to stimulate human
breast cancer cells, (MC-7 cells), to enter the cell cycle …”.
--- Note: At
the end of this full research paper, Dees concluded that “…
women should not
consume particular foods, (eg. Soy-derived
products), to prevent breast cancer …”.
Also see Dees C.
, on pages 37 and 73.
... / 75
- 75 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i -
- http://www.soyonlineservice.co.nz/articles/Metzler.htm
… and … http://www.soyonlineservice.co.nz/04soy&DES.htm
.
1998 “Genotoxicity
of estrogens,” – Metzler M., Kulling
S.E. and others, Z
Lebensm Unters Forsch A., 1998, 206: 367-73.
— Genotoxic effects of the
endogenous mammalian estrogen 17-beta-estradiol and the synthetic estrogen diethylstilbestrol
have recently been demonstrated, e.g. the induction of numerical chromosome
aberrations (aneuploidy,
i.e. the condition in which on or more whole chromosomes of a normal set are
missing or present in more than the usual set of copies) and the formation of
deoxyribonucleic acid (DNA) adducts.
— It is likely that the
genotoxicity of the estrogens acts in concert with their hormonal activity to
give rise to carcinogenic effects.
— Many of the phytoestrogens
that occur in plants and the numerous anthropogenic estrogens in our
environment, which are ingested in food, have not yet been examined for
their genotoxic potential. Recent
studies have demonstrated that some but not all of these estrogens exhibit
genotoxicity.
— The type and strength of the
genotoxicity strongly depends on the chemical structure and does not correlate
with estrogenicity.
— For example, coumestrol and genistein are clastogenic in cultured mammalian
cells and lead to gene mutations, whereas biochanin-A and bisphenol-A have the
potential to aneuploidy.
— Daidzein, enterolactone, enterodiol and certain bisphenols are devoid of
genotoxic effects. The genotoxicity should be determined individually for each
estrogen & taken into account in assessment of - carcinogenic risk.
n
1999 “Cytotoxic
potential of the phytochemical genistein isoflavone
(4',5',7-trihydroxyisoflavone) and certain environmental chemical compounds on
testicular cells,” — Kumi-Diaka J,
Nguyen V, Butler A.,
Biol Cell 1999 Sep;91(7):515-23., Florida Atlantic University, Department of Biology,
College of Liberal Arts & Sciences, Davie 33314, USA.
; i ; —
The results from the data obtained demonstrated: 1.) that incubation of testis cells with each of
the agents (Gn, dxm, naz) alone and in two combinations (Gn-dxm, and Gn-naz)
induced significant testicular cell death; 2.)
that both genistein and dexamethasone mostly and significantly induced
apoptotic cell death
while sodium azide induced necrotic cell death; 3.) that addition of dexamethasone to genistein
demonstrated synergism in apoptosis on testis cells; and 4.)
that combination of naz with Gn demonstrated synergism in necrosis on
testis cells even though Gn alone did not induce significant necrosis.
i i i , i i i , i i i , i i i
2000 “Ecological
study of the association between soy product intake and mortality from cancer
and heart disease in
— Soy protein intake was significantly correlated with stomach cancer mortality rate
in men after controlling
for total energy, alcohol and salt intake,
the mean age and proportion of current smokers in the prefecture (r =
-0.31, P = 0.04). Soy product intake estimated as total amount as well as
isoflavone and soy protein intake were significantly
positively correlated with colorectal
cancer mortality rates in both sexes (for total amount, r = 0.32, P = 0.03 in men and r = 0.44, P =
0.001 in women) after controlling for covariates. Inverse correlation between
soy product intake (as total amount or soy protein) and heart disease mortality
rate was statistically significant in women after controlling for covariates.
... / 76
- 76 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i
-
http://www.eurekalert.org/pub_releases/2001-05/NIoE-Iucs-3005101.php
.
2001 “Increased
uterine cancer seen in mice injected wit genistein, a soy estrogen, as
newborns,” – Newbold, Wendy, Jefferson
and Elizabeth Padilla; Bill C.I.
— “The data suggest that genistein is carcinogenic if exposure occurs during critical
periods in a young animal’s development”.
The finding is similar to work Newbold did with diethylstibestrol-(DES) exposure in unborn mice. DES is a powerful synthetic estrogen, while genistein is a much
weaker estrogenic agent made by plants. DES was previously given to pregnant mothers
to prevent miscarriages and was uksed as a food additive to fatten chickens and
cattle.
— All uses of DES in the
i i i , i i i , i i i
2001 “Incidence of
squamous neoplasia of the cervix and vagina in women exposed prenatally to
diethylstilbestrol (
; i ; —
Women exposed prenatally to diethylstibestrol (DES) have an excess risk of clear-cell
adenocarcinoma of the vagina and cervix. The findings support an
association between in-utero DES exposure and high-grade squamous neoplasia.
i i i , i i i , i i i , i i i - genistein, alone or in
combination with dxm, significantly interfered
with
percentage sperm motility and caused significant detachment of sperm heads
2001 “Effects of
Genistein Isoflavone (4',5',7-Trihydroxyisoflavone) and Dexamethasone on
Functional Characteristics of Spermatozoa,” – Kumi-Diaka J, Townsend J., J Med Food 2001 Spring;4(1):39-47 ,
— Caudal epididymal spermatozoa were used to study the influence of
genistein isoflavone and dexamethasone (dxm) on the functional
characteristics of spermatozoa ...
— The overall results indicated, (1-5), that (4)
higher doses of genistein, alone or in combination with
dxm, significantly interfered with percentage sperm motility and caused
significant detachment of sperm heads but did not cause
morphological defects; and (5) higher doses of genistein
caused significant decrease in sperm acrosome reactivity with long duration of
exposure.
; i ; — In
view of the fact that sperm capacitation and AcR are physiological
prerequisites for successful fertilization of oocytes, the findings suggest that chronic exposure of spermatozoa to high
doses of genistein could be associated with infertility problems
through suppression/inhibition of AcR and sperm motility.
... / 77
- 77 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - Malnutrition ...
from ... False nutritional beliefs.
Infants
on Soy milk and Rice milk with severe nutritional
deficiencies
2001 “Severe
nutritional deficiencies in toddlers resulting from health food milk
alternatives,” –
; i ; Malnutrition
... from ...
False Nutritional Beliefs
Infants
on Soy milk and Rice milk with severe nutritional
deficiencies
— Because nutritional deficiencies are uncommon in the
— Case (1.) a 22-month-old male child,
with a history of chronic eczema and perceived milk intolerance. He was started
on a rice beverage
after weaning.
— Kwashiorkor impairs cellular
immune defenses and electrolyte imbalances with ongoing diarrhea. Observed
typical features of kwashiorkor: generalized edema, hyperpigmented and
hypopigmented skin lesions, abdominal distention, irritability, and thin,
sparse hair.
— Case (2.) a 17-month-old black male,
Growth and height arrest after 9 months on soy milk.
Reported regression in gross motor milestones, patient was unable to
crawl or roll over. Generalized hypotonia, weakness, and decreased muscle bulk
were present.
— Patient was diagnosed with rickets. Clinical features of rickets present on
examination included: frontal bossing, an obvious rachitic rosary
(photographed), genu varus, flaring of the wrists, and lumbar kyphoscoliosis.
The published radiographs are diagnostic of advanced rickets, showing diffuse
osteopenia, frayed metaphyses, widened epiphyseal plates, and a pathologic fracture
of the ulna.
— In addition,
the serum alkaline phosphatase and parathyroid hormone level were markedly
elevated, and Phosphorus and the 25-hydroxy-vitamin D level were low, Calcium
was low normal.
i i i , i i i , i i i , i i i - “Caution is
warranted ... for women with breast cancer”
- http://www.eurekalert.org/pub_releases/2001-11%20uoia-efi110101.php
, and ...
2001 “Estrogen found
in soy stimulates human breast-cancer cells in mice,” – William G. Helferich, J Nutr - (Nov.), Carcinogenesis - (Oct.),
Cancer Res - (July), 3 studies funded by National Institute of Health, an
ElurekAlert Press Release., Nov 1, 2001.
— Results demonstrate that genistein in various forms stimulates
tumor growth. In Journal of Nutrition, Heiferich and
colleagues show that the estrogen-dependent tumors implanted into experimental
mice models grow at a rate in proportion tothe levels
of genistein consumed. Genistein at or above 250 parts per million,
a dosage that produces blood levels similar to what is observed in women
consuming soy diets.
— The researchers, Cancer
Research, found that estrogen-dependent tumor growth increased as the isoflavone
content increased in the soy-containing diet, and that the conversion of
genistin to genistein in the body begins with contact - with saliva in the
mouth.
; i ; —
“Our pre-clinical laboratory animal data suggest that caution is warranted
regarding the use of soy supplements high in isoflavones for women with breast
cancer, particularly if they are menopausal.”
... / 78
- 78 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i - results in decreased
absorption of levothyroxine
2001 “Use of Soy
protein supplement and resultant need for increased dose of
levothyroxine,” – Bell D.S., Ovalle F.,
Endocr Pract May-June 2001; 7(3):193-4, Division of Endocrinology
and Metabolism,
— OBJECTIVE: To
report a case of difficulty in achieving suppressive serum levels of thyroid
hormone because of malabsorption of exogenous levothyroxine attributable to
daily ingestion in close temporal relationship to the intake of a soy
protein-containing food supplement.
— CONCLUSION:
Administration of levothyroxine concurrently with a soy protein dietary
supplement results in decreased absorption of
levothyroxine and the
need for higher oral doses of levothyroxine to attain therapeutic serum thyroid
hormone levels.
i i i , i i i , i i i - Visual spatial memory is
enhanced in female rats ... inhibited in males
2001 “Visual spatial
memory is enhanced in female rats (but inhibited in males) by dietary Soy
phytoestrogens,” – Lund T.D., West
T.W., and others,
BMC Neurosci., 2001;2(1).Epub 2001 Dec 17.,
Neuroscience Center Brigham Young Univ., Provo, Utah, USA. Neuroscience@byu.edu
— BACKGROUND:. In
learning and memory tasks, requiring visual spatial memory (VSM), males exhibit
superior performance to females (a difference attributed to the hormonal
influence of estrogen). This study examined the influence of phytoestrogens (estrogen-like plant compounds) on VSM,
utilizing radial arm-maze methods to examine varying aspects of
memory. Additionally,
brain phytoestrogen, calbindin (CALB), and cyclooxygenase-2 (COX-2) levels were
determined.
— RESULTS:. Female
rats receiving lifelong exposure to a high-phytoestrogen containing diet
(Phyto-600) acquired the maze faster than females fed a phytoestrogen-free diet
(Phyto-free); in males the opposite diet effect was identified. In a separate
experiment, at 80 days-of-age, animals fed the Phyto-600 diet lifelong either
remained on the Phyto-600 or were changed to the Phyto-free diet until 120
days-of-age. Following the diet change Phyto-600 females outperformed females
switched to the Phyto-free diet, while in males the opposite diet effect was
identified.Furthermore, males fed the Phyto-600 diet had significantly higher
phytoestrogen concentrations in a number of brain regions (frontal cortex,
amygdala & cerebellum); in frontal cortex, expression of CALB (a
neuroprotective calcium-binding protein) decreased while COX-2 (an inducible
inflammatory factor prevalent in Alzheimer's disease) increased.
— CONCLUSIONS:. Results
suggest that dietary phytoestrogens significantly sex-reversed the normal
sexually dimorphic expression of VSM. Specifically, in tasks requiring the use
of reference, but not working, memory, VSM was enhanced in females fed the
Phyto-600 diet, whereas, in males VSM was inhibited by the same diet. These findings suggest that dietary soy derived phytoestrogens can
influence learning and memory & alter the expression of proteins involved
in neural protection and inflammation in rats.
; i ; My question is ... ?? ... Should male airplane pilots be
prohibited, forbidden, from eating soy, or should male pilots be replaced with
women pilots, and then the men could become the stewardess, and the stewardess
could become the better pilots ??.
...
/ 79
- 79 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
n
i i i , i i i , i i i , i i i , (+) i i i - estrogenic substances should also be considered
"male hormones."
-
http://www.soyonlineservice.co.nz/07abstract.htm
.
- http://www.soyonlineservice.co.nz/07abstract.htm#ODonnel%20et%20al%202001 .
2001 “Estrogen and
spermatogenesis,” — O'Donnell L,
Robertson KM, and others, Endocr Rev 2001 Jun;22(3):289-318 Prince Henry's Institute of Medical
— Although it has been known
for many years that estrogen administration has deleterious effects on male
fertility, data from transgenic mice deficient in estrogen receptors or
aromatase point to an essential physiological role for estrogen in male
fertility.
— This review summarizes the current knowledge on the localization
of estrogen receptors and aromatase in the testis in an effort to understand
the likely sites of estrogen action.
— The review also discusses the many studies that have used models employing the
administration of estrogenic substances to show that male fertility is
responsive to estrogen, thus
providing a mechanism by which inappropriate exposure to estrogenic
substances may cause adverse effects on spermatogenesis and male
fertility. The
reproductive phenotypes of mice deficient in estrogen receptors alpha and/or
beta and aromatase are also compared to evaluate the physiological role of
estrogen in male fertility.
— The review focuses on the effects of estrogen administration or deprivation, primarily
in rodents, on ... the
hypothalamo-pituitary-testis axis ... testicular function (including Leydig
cell ... Sertoli cell ... and germ cell development and function) ... and in
the development and function of the efferent ductules and epididymis. The requirement for estrogen in normal
male sexual behavior is also reviewed, along with the somewhat limited data on
the fertility of men who lack either the capacity to produce or respond to
estrogen.
; i ; —
This review highlights the ability of exogenous estrogen exposure to perturb
spermatogenesis and male fertility, as well as the emerging physiological role
of estrogens in male fertility, suggesting that, in this local context,
estrogenic substances should also be considered
"male hormones."
i i i , i i i , i i i , i i i - Wildlife experience and
animal studies have provided evidence ...
2002 “Impact of
exposure to endocrine disrupters in utero and in childhood on adult
reproduction,” –
— Recent reports have demonstrated a decline in human male
reproductive health: high and probably increasing prevalence of cryptorchidism
and hypospadias, low and probably decreasing semen quality, a rising incidence
of testicular cancer and a growing demand for assisted reproduction.
— These changes seem to be
interrelated and may be symptoms of a common underlying entity, the testicular
dysgenesis syndrome, with foundations in fetal life due to adverse
environmental influences.
— Wildlife experience and animal studies have provided evidence
that fetal or perinatal exposure to endocrine disrupters results in disturbed
sexual differentiation and urogenital malformations followed by decreased
reproductive health in adult life.
— This chapter reviews
existing evidence for a connection between ...
(1.) exposure to endocrine
disrupters in fetal life and childhood and
(2.) adult reproductive health in
humans.
— This topic is not only
relevant to basic scientists but also to clinical endocrinologists, who should
also be encouraged to participate in research concerning this problem.
... / 80
- 80 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i
2002 “Neonatal
exposure to genistein induces estrogen receptor (ER)alpha expression and
multioocyte follicles in the maturing mouse ovary: evidence for ERbeta-mediated
and nonestrogenic actions,” –
— These data taken together
demonstrate alterations in the ovary following neonatal exposure to genistein. Given
that human infants are exposed to high levels of genistein in soy-based foods,
this study indicates that the effects of such exposure on the developing
reproductive tract warrant further investigation.
i i i i i i , i i - http://www.soyonlineservice.co.nz/04immunefunction.htm
.
2002 “Early exposure
to genistein exerts long-lasting effects on the endocrine and immune systems in
rats,” – Klein S.L., Wisniewski A.B.,
Marson A.L., and others, Mol
Med 2002 Nov;8(11):742-9., The W. Harry Feinstone
Department of Molecular Microbiology and Immunology, The Johns Hopkins
Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.
— Discussion: These data
illustrate that exposure to genistein during pregnancy and
lactation exerts long-lasting effects on the endocrine and immune systems in
adulthood. Whether
exposure to phytoestrogens during early development affects responses to
infectious or autoimmune diseases, as well as cancers, later in life requires
investigation.
i i i , i i i , i i i , i i i , i - Risks versus Benefits
... breast cancer patients should be informed that
phytoestrogens
have the potential to stimulate tumor growth.
2002 “Safety Issues
of Soy Phytoestrogens in Breast Cancer Patients,” — de Lemos M., J Clin Oncol, Volume 20(13),
— Risks versus Benefits
... breast cancer patients
should be informed that
phytoestrogens have the potential to stimulate tumor growth.
– http://www.jco.org/cgi/content/full/20/13/3040
... Safety Issues of Soy Phytoestrogens in Breast Cancer Patients
Mário de
Lemos
To the
Editor:
; i ; — The results of Van Patten et al 1 confirmed previous findings 2 that soy phytoestrogens
have minimal efficacy for menopausal symptoms in breast cancer patients. However,
I am concerned that patients in neither study were apparently (not) informed of
the potential stimulatory effects of phytoestrogens on breast tumor. 3
Similar omission would have raised ethical concerns if pharmaceutical drugs
were involved.
— At concentrations below 10 Fmol/L, phytoestrogens can stimulate breast
tumor growth 4-15 and antagonize the
antitumor effects of tamoxifen, 7,9 particularly in an
environment of low endogenous estrogen.3,11 In contrast, phytoestrogens
inhibit breast tumor growth and enhance the antitumor effects of tamoxifen at
concentrations above 10 Fmol/L. 5,6,8,9,11 In
humans, serum phytoestrogen concentrations attained after acute or chronic
intake of phytoestrogens were much lower than 10 Fmol/L. 1,16,17
— Without long-term human data, cancer risk assessments need to be cautious
and assume that substances that promote tumor growth in preclinical studies may
pose similar risks clinically. 18 Hence, to weigh the potential risks versus benefits before using phytoestrogens for unproven
indications, breast cancer patients should be informed that phytoestrogens have
the potential to stimulate tumor growth.
Mário de Lemos
... / 81
- 81 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
i i i , i i i , i i i , i i i - Bladder Cancer - (Soy industry is not promoting the results
of this study !.)
2002 “Dietary soy
and increased risk of bladder cancer: the
; i ; —
The association between Soyfood consumption and subsequent bladder cancer risk
was investigated in a population-based cohort study, the “Singapore
Chinese Health Study”. As of
— Similar results were
obtained for intakes of Soy protein and Soy isoflavones. The Soyfood–bladder cancer risk association
did not differ significantly between men and women and was not explained by
other dietary factors. The Soy-cancer
relationship became stronger when the analysis was restricted to subjects with
longer (> or =3 years) duration of follow-up. To our knowledge, this is the FIRST epidemiological report on the effect of
dietary Soy on bladder cancer risk.
i i i , i i i , i i i , i i i , i i -
DNA double strand breaks leading to chromosomal
aberrations and leukemia’s.
Further studies on the role of dietary topoisomerase II-poisons
are urgently required.
-
http://www.giftinfo.uni-mainz.de/EXCLI/volumes/Vol1/2002volume1pp8-14.pdf
.
2002 “Dietary
topoisomerase II-poisons: contribution of soy products to infant leukemia ?,” –
Jan G. Hengstler, Carolin K. Heimerdinger
and others, EXCLI
Journal 2002;1:8-14 (ISSN 1611-2156), received: Dec 19, 2002, accepted Dec 29, 2002,
published Dec 30, 2002. Institute of Legal Medicine, Department of
Molecular Toxicology, University of Leipzig, Johannisallee 28, 04103 Leipzig, Germany;
Institute of Toxicology and Department of Gynecology, University of Mainz,
Mainz, Germany
— DNA topoisomerases are nuclear enzymes inducing transient breaks
in DNA allowing DNA strands or double helices to pass through each other. Clinically used DNA
topoisomerase II-poison etoposide is known to induce DNA
double strand breaks leading to chromosomal aberrations and leukemias.
— Recently, some alarming studies have been published, suggesting
that maternal exposure to low doses of dietary topoisomerase II-poisons,
including bioflavonoids such as genistein or quercetin, may contribute
to the development of infant leukemia: approximately 80% of infants with acute myelogenous leukemia
(AML) and acute lymphoblastic leukemia (ALL) have chromosome translocations
involving the MLL (mixed lineage leukemia) gene ... These observations are
relevant, since many foods contain topoisomerase II-poisons, predominantly soy and Soy
products, but also coffee, wine, tea, cocoa, as well as some fruits and
vegetables.
— Further studies on the role of dietary topoisomerase II-poisons
are urgently required. If
the casual relationship between dietary exposure and topoisomerase II-poisons
and infant leukemia will be confirmed, care should be taken to reduce exposure
to critical foods during pregancy.
; i ; —
What this study and its abstract does not say is that soy is of many magnitude
greater danger
scientifically than coffee, wine, tea, cocoa and some fruits and
vegetables. By leaving this fact out,
the inexperienced reader may/will become confused and/ or misinformed, and this
info can be used to unduly sway the wrong belief to the public.
Google Search ... Dietary
bioflavonoids induce cleavage in the MLL gene and may contribute to infant
... / 82
- 82 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
.
n
-
http://www.soyonlineservice.co.nz/07abstract.htm
... Scientific Investigations
2002 “Serum plant
sterols as a potential risk factor for coronary heart disease,” — Sudhop T, Gottwald BM, von Bergmann K., Metabolism. 2002 Dec;51(12):1519-21., Department of
Clinical Pharmacology,
; i ; — In
patients with the inherited disease of phytosterolemia, elevated concentrations
of plant sterols (eg, campesterol and sitosterol) have been implicated as a
risk factor for premature atherosclerosis. Whether plasma concentrations of campesterol and
sitosterol are risk factors for coronary heart disease (CHD) in nonphytosterolemia
subjects has not been established.
— Therefore, the present study examined the role of plant sterols in patients
admitted for elective artery coronary bypass graft (ACBG). Serum concentrations
of campesterol and sitosterol, as well as lathosterol, desmosterol,
cholestanol, and lipoproteins were analyzed in 42 men and 11 women without
lipid-lowering treatment during the past. Twenty-six patients reported a
positive family history in their first-degree relatives for CHD. Lipid profile
and other risk factors were comparable in both groups.
— Patients with a positive family history for CHD had significant higher
plasma levels of campesterol (.50 +/-.17 v.38 +/-.16 mg/dL; P =.011),
sitosterol (.40 +/-.11 v.31 +/-.11 mg/dL; P =.004) and their ratios to
cholesterol. Lathosterol, desmosterol, cholestanol, and their ratios to
cholesterol were not significantly different. Analysis of covariance (ANCOVA) analysis showed no
influence of sex, age, triglycerides, total-, low-density lipoprotein (LDL)-,
and high-density lipoprotein (HDL)-cholesterol on the results, but confirmed
a strong influence of plant sterols.
— These findings support the hypothesis that plant sterols might be an
additional risk factor for CHD.
n
2002 “Estrogen
receptor expression in the prostate of rats treated with dietary genistein,” — Dalu A., Blaydes B.S., Bryant C.W., and others, J Chromatogr B Analyt Technol Biomed Life
Sci. 2002
Sep 25;777(1-2):249-60., Division of
Biochemical Toxicology, National Center for Toxicological Research, Food and
Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA.
— Steroid hormones and their receptors play critical roles in the
growth, development, and maintenance of the male reproductive tract. Genistein,
a naturally occurring isoflavonoid primarily found in soybeans, interacts with
estrogen receptors alpha and beta (ER alpha and beta), with preferential
affinity for ER beta.
— This is one mechanism
whereby genistein may affect growth and development and potentially alter
susceptibility to carcinogenesis. Previous studies have indicated effects of
soy and/or genistein in the male rodent reproductive tract under certain
exposure conditions. The current study was undertaken to determine if
modulation of the expression of ER alpha and ER beta by dietary genistein may
contribute to those effects.
— Rats in a two-generation study were fed 0, 5, 100, or 500 ppm genistein prior to mating
and through pregnancy and lactation. At weaning, male pups were selected in
each of the F(1) and F(2) generations and half of the pups continued on the
same diet as their dams (G/G, continuous exposure) while their litter mates
were placed on control chow (G/C, gestational and lactational exposure) until
sacrifice on PND 140. Male reproductive organ weights, serum levels of
testosterone and dihydrotestosterone (DHT), and ER alpha and ER beta protein
levels in the ventral and dorsolateral prostate were the endpoints measured.
Prostate sections were also evaluated microscopically.
— Statistically significant elevations in testosterone and DHT were
observed in PND 140 animals from the F(1) generation, but they were not
accompanied by organ weight changes. Body weight in the continuously dosed 500 ppm F(1) PND 140
animals was depressed relative to control, but organ weights in animals of
either generation showed few treatment-related effects. While estrogen receptor
levels were quite variable, levels of ER beta in the dorsolateral prostate were
significantly depressed in all dose groups in the G/C exposure and the high
dose group of the G/G exposure in F(1) rats, but not in F(2) rats.
; i ; —
Given the growing body of knowledge on the significance of ER beta in the
prostate, the evidence for apparent down regulation of this receptor by
genistein may have implications for
reproductive toxicity and
carcinogenesis that warrant further
investigation.
... / 83
- 83 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
.
n Study only done for one week, not the “at
least three months”
required by the WHO
i i i , i i i , i i i , i i i , (+) i i i - as needed and required
by WHO/CODEX Standard for Soy … See page 6.
2002 “Regulation of
male sex hormone levels by soy isoflavones in rats,” — Yi M.A., Son H.M., Lee
J.S., and others, Nutr
Cancer 2002 ;42(2):206-10., Department of Animal Science and Biotechnology,
Kyungpook National University, Taegu 702-701, South Korea.
— Several studies have
suggested that soybean intake is associated with a lower risk of prostate
cancer. However, the
mechanism of prostate cancer prevention by soybeans remains unclear.
— Because prostate cancer is reported to have an association with
an increased level of dihydrotestosterone (DHT) and soybean isoflavones are known to inhibit 5 alpha-reductase,
which is involved in the conversion of testosterone to DHT, the effects of soybean
extract and
isoflavones on the plasma
levels of male sex hormones were investigated using male rats. In Experiment I,
Sprague-Dawley rats were fed diets with and without soy flour; in Experiment
II, rats were fed diets containing 2% soy methanol extract or 0.2% semipurified
isoflavones or a control diet.
— The study showed a reduction of plasma DHT along with an increase
in total plasma androgen in rats fed soy flour or semipurified isoflavones for 1 wk. These results suggest that soy isoflavone
intake may reduce plasma DHT level.
n
i i i , i i i , i i i , i i i , (+) i i i - GEE
WHIZ !!. … But never -- never
ever tell the consumer this truth !!.
2003 Determination
of isoflavones in ready-to-feed soy-based infant formula. — Johns P, Dowlati
L, Wargo W., J
AOAC Int. 2003 Jan-Feb;86(1):72-8., Abbott Laboratories, Ross Products Division, 3300
Stelzer Rd, Columbus, OH 43219, USA. paul.johns@rossnutrition.com
— An alkaline
hydrolysis/liquid chromatography (LC) method was developed for determination of
isoflavones in ready-to-feed soy-based infant formula. The method consists of a
15 min methanol extraction, 10 min alkaline hydrolysis, HCl neutralization,
gravity filtration, aqueous dilution, and 50 min LC analysis with UV detection
at 262 and 250 nm to quantify 6 isoflavone analytes: daidzin, glycitin, genistin,
daidzein, glycitein, and genistein. The concentration averages for 10
commercial batches (microg aglycone/g formula) were daidzein, 6.12 +/- 1.23; glycitein, 1.19 +/- 0.16;
genistein,
12.8 +/- 2.35; and total, 20.1 +/- 3.61. Validation experiments demonstrated
extraction completion and analyte stability to alkaline hydrolysis. Spike
recoveries ranged from 97.6 to 104.1%, and a series of accuracy assessments
showed that isoflavone concentration determined by the method was within 5% of
the true value. The relative standard deviation values for repeatability ranged
from 0.4 to 2.2% (n = 10), and from 0.3 to 2.7% (n = 4) for intermediate
precision. Isoflavone peak purity was verified by comparing sample and standard
peak area ratios (262/250 nm). The limits of detection and quantitation
(microg/ formula) ranged from 0.02 to 0.05 and 0.08 to 0.18 microg/g,
respectively.
; i ; —
The difference between our concentrations and those reported by others in 1995-1998
is attributable to the well-established seasonal variation in
soybean isoflavone levels.
Although the method was applied exclusively to ready-to-feed formula in the
present study, it is equally suitable for powder and concentrated liquid infant
formulas.
n - Website below was last
up-dated on Nov 2004
i i i , i i i , i i i , i i i , (+) i i i - Poisonous Plant database -
Center For Food Safety, Applied Nutrition
-
http://www.cfsan.fda.gov/~djw/plantox.html
… http://www.cfsan.fda.gov/~djw/pltx.cgi?QUERY=soy
… see Items # 165, 192, 246
1907 … “Plant names scientific and popular,” --- Lyons, A.B., Nelson, Baker Co, Detroit, [ English ]
1911 … “A manual of poisonous plants,” --- Pammel, I. H., Torch Press. Cedar Rapids,
Iowa [ English ]
1916 … “Cases of
poisoning in cattle by feeding on meal from SOYA bean after extraction of the
oil,” — S.
Stockman, J Comp Pathol Exp Therapeut, 29, 2,
95-107, US FDA Poisonous Plant Database, See
scientific abstract item
#246 out
of 271 listed, last up-dated Nov 2004,
(FDA file #:
F06318), Center For Food Safety And Applied
Nutrition,
CFSAN / Office of Plant
and Dairy Foods.
; i ; — This
— Information herein is in the
public domain, and is continually increasing.
— For information or concerns
about the toxicity of plants, contact the local
— For a poisoning emergency,
call 1-800 - 222 - 1222. If the victim
has collapsed or is not breathing, call 911.
--- Also see page 126 ... / 84
- 84 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
.
Please note: the i does not indicate magnitude of importance
scientifically, it only indicates order of importance to me, Gerald Hernesmaa, volunteer, Health
Action Network Society and S.O.S. … healthwise933@shaw.ca
Also see links … http://www.soyonlineservice.co.nz/abstracts.htm#Abstract%205 … Abstracts - Scientific
Investigation,
and … http://www.soyonlineservice.co.nz/abstracts%202.htm … Abstracts - Scientific
Investigations - 2 (Cont.)
and … http://www.soyonlineservice.co.nz/abstracts%204.htm … Abstracts - Scientific
Investigations - 3 (Cont.)
*
New Website format …
Fall 2005 - abstract pages
have been consolidated into … http://www.soyonlineservice.co.nz/07abstract.htm
...
and
… Birth Defects … Infertility … Cancer … Immune – DNA Damage … Brain Damage …
Toxins – Osteoporosis … etc.
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
i i i , i i i , i i i , i i i
Osteoporosis and
Soy Abstracts
Soy Toxins
. http://www.soyonlineservice.co.nz/03toxins.htm
.
; i ;
Soy
contains several naturally occurring compounds that are toxic to
humans and animals. The soy industry frequently refers to these toxins as ...
anti-nutrients ... which implies that they somehow act to prevent the
body getting the complete nutrition it needs from a food.
Soy toxins (such as phytic acid) can certainly
act in this manner, but they also have the ability to target specific organs,
cells and enzyme pathways and their effects can be devastating.
The
Soy toxins that Soy Online Service have concerns about are ... protease
inhibitors ... phytic acid ... soy lectins-(or haemagglutins) ... nitrosamines
... manganese concentrations ... and the mysterious soyatoxin. Nitrosamines are not naturally occurring in soybeans
but form during the processing of products such as isolated soy protein (ISP),
(SPI).
... Protease-(enzymes)
Inhibitors ...
Perhaps the best known of the soy toxins
are the protease inhibitors (also referred to as trypsin inhibitors) which, as the name suggests, are able to
inhibit the action of proteases (including trypsin) which are
enzymes that are involved in the process of dismantling proteins for use by the
body.
“High
levels” of exposure
to protease inhibitors (such as that found in raw soy flour) cause pancreatic cancer, whereas “moderate levels” cause
rat pancreas to be more susceptible to cancer-causing agents. Validity
of the rat model to humans has been questioned & the US FDA have examined
effects of protease inhibitors on Cebus monkey (JP Harwood et al., Adv Exp Med Biol 1986
199: 223-37).
The parameters of
the Cebus Monkey study were as follows
Number
of Trypsin
Inhibitor
Group monkeys Dietary Protein (mg/g of
diet)
1 8 Lactalbumin 0.12
2 10 Soy Isolate 0.54
3 6 Casein 0.08
4 2
Soy Concentrate 2.41
Note:
Make sure the label
on your vitamins, minerals, and medications says … contains no Soy …
or … contains no Soy ingredients
.
Pet Food, farm animal foods ... / 85
- 85 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
After 5 years of chronic ingestion to low
levels of trypsin inhibitors, there was no discernible pancreatic damage effect
in monkeys from groups 1-3. However,
one monkey in group 4 exhibited moderate diffuse acinar atrophy, moderate
diffuse interstitial fibrosis & moderate chronic pancreatitis in all three
sections of tissue examined. Minimal lymphoid hyperplasia was noted in the
other group 4 monkey.
Therefore, there is good reason to question claims
that low levels of soy protease inhibitors pose no threat to human health.
Soy
Online Service has noted that there is considerable variability in the levels
of protease inhibitors in commercially available foods and that there is little to protect
consumers from exposure to high levels of protease inhibitors. For example, a
study entitled 'Trypsin inhibitor levels in soy-based infant formulas &
commercial soy protein isolates & concentrates (RW Peace et al., 1992, Food Res Int, 25: 137-141) found trypsin inhibitor levels were as
high as 2.72 mg/g in ready to feed soy formulas and 7.30 mg/g in soy protein
concentrate.
There is no established acceptable levels
of protease inhibitors in foods and no protection from short-term high level
(acute) exposures or long term low level (chronic) exposures.
Phytates
The
term phytate refers to several compounds that are based on phytic acid
(inositol hexaphosphate). It is the presence of multiple phosphates in phytates
that makes them effective chelating agents, i.e. they have the ability to bind
to certain metal ions.
Obviously if metals are bound up in a phytate-complex, they are less available
to the body ( i.e. less bio-available) for nutritive purposes.
Phytates
are particularly adept at binding metals in their so-called divalent state,
metal ions such as ... calcium (Ca2+) ... copper (Cu2+)
... iron (Fe2+) ... manganese (Mn2+) ... zinc (Zn2+).
Soybeans
contain very high levels of phytates … http://www.soyonlineservice.co.nz/articles/Phytate.htm
.
and there is numerous reports
of reduced bio-availability of various metals from foods containing soy; this
hasparticular significance for vegetarians and infants fed soy-formulas.
1986 “New
Chromophore for Phytic Acid Determination,” –
Mohamed A.I., Ponnamperuma
A.J.P., Hafez Y.S., Cereal
Chem 1986,
63:6 475-8.
— Among the legumes
investigated, soybean has the highest value of
(23.35 mg/g of meal),
whereas black-eyed pea had the lowest (8.74 mg/g of meal).
1982 “Analysis of
Phytic Acid in Foods by HPLC,” – Camire AL, Clydesdale FM,
J Food Sci 1982,
47: 575-8
1995 “Variability in
Phytic Acid Content and Protein Digestibility of Grain Legumes,” – Chitra U, Vimala V, Singh U, Geervani P., Plant Foods Hum Nutr 1995
Feb., 47:2 163-72.
Vegetarians, particularly young women vegetarians,
need to be aware that soy products affect their iron and zinc requirements and it has been
recommended that they utilize strategies that minimize the intake of dietary
phytate.
See
… http://www.soyonlineservice.co.nz/articles/Veges.htm
.
... / 86
- 86 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
Minimize the intake of dietary phytate … http://www.soyonlineservice.co.nz/articles/Veges.htm
…
1997 “Dietary
strategies to improve the iron & zinc nutriture of young women following a
vegetarian diet,” – Gibson R.S.,
Donovan U.M., Health A.L., Plant
Foods Hum Nutr 1997 51:1 1-16
— Dietary strategies to
enhance the content and bioavailability of iron and zinc in vegetarian diets
were compiled. Strategies included increasing promoters and decreasing
antagonists of iron and zinc absorption, adopting food preparation and
processing methods which hydrolyze the phytate content of cereals and legumes,
and using iron cookware. These strategies
were used to devise two vegetarian menus based on food consumption patterns
derived from three day weighed food records of 78 Canadian lacto-ovo-vegetarian
adolescents. The iron and zinc, as well
as calcium, phosphorus, thiamin, riboflavin, niacin, vitamin A, protein and
energy content of the devised menus were all higher than the actual intakes and
the corresponding Canadian recommended nutrient intakes.
— Results show ...
the overall nutrient adequacy of the recommended vegetarian menus and indicate
that young lacto-vegetarian women can potentially meet their estimated dietary
requirements for absorbed iron and zinc through modest modifications to the
diet. Laboratory studies designed to measure the total amount of iron and zinc
absorbed from these diets by young vegetarian women are needed to verify the
efficacy of the devised menus.
The effects of phytate in infant
soy-formulas are a great concern
Iron
& zinc requirements of developing infants are well documented,
particularly those that relate cognitive function, see Cognitive Function (Iron Absorption) … http://www.soyonlineservice.co.nz/03toxins.htm
… There is no question that infants fed soy-formulas are at greater
risk of reduced up-take of various essential minerals compared with breast-fed
infants or infants fed other formulas.
High levels of
phytate … http://www.soyonlineservice.co.nz/articles/Phytate.htm
… Soybeans are highest.
1986 “New
Chromophore for Phytic Acid Determination,” – Mohamed A.I., Ponnamperuma A.J.P., Hafez Y.S., Cereal Chem 1986 63:6 475-8.,
— A direct spectrometric
method was developed to analyze phytic acid without acid digestion. The method
was based on the precipitation of phytate as ferric phytate followed by
conversion to sodium phytate. On heating, phytate reacted with a chromogenic
agent and a blue molybdenum complex was formed. The new chromophore was used to
determine phytic acid in 8 legume seeds.
— Among legumes investigated, soybean has the highest value (23.35 mg/g of meal), whereas black-eyed
pea had the lowest (8.74 mg/g of meal)
1982 “Analysis of
Phytic Acid in Foods by HPLC.,” – Camire
AL, Clydesdale F.M, J Food Sci 1982
47: 575- 8
— A quantitative HPLC method
for the analysis of phytic acid in foods was developed based on the
precipitation of phytic acid with ferric chloride followed by conversion to
sodium phytate before injection onto a C-18 reversed phase column.
Results
Foodstuff
Phytic Acid (mg/g) Foodstuff Phytic Acid (mg/g)
Hard red wheat bran 68.8 " 1.85 Parsnips 8.18 " 0.18
Soft white wheat bran 50.27 " 1.45 Split peas 16.79 " 1.02
Soy flour (defatted) 22.45 "
1.15 Broccoli ...
... ... ... Not detected
Refined corn bran 15.77 " 2.51 Brown rice 15.55 " 1.92
... / 87
- 87 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
1995 “Variability in
phytic acid content and protein digestibility of grain legumes,” – Chitra U., Vimala V., Singh U., Geervani
P., Plant
Foods Hum Nutr 1995 Feb 47:2 163-72.
— Several genotypes, number
given within parenthesis, of chickpea, pigeonpea, urd bean, mung bean and soybean, differing in seed characteristics were
analyzed for phytic acid, in vitro protein digestibility (IVPD), protein, total
phosphorus, and seed size. Phytic
acid contents and IVPD
values differed significantly among and within these species. Phytic acid content (mg/g) was the highest in soybean
(36.4) followed by urd bean (13.7), pigeonpea (12.7), mung bean (12.0) and
chickpea (9.6). On
an average, phytic acid constituted 78.2 percent of the total phosphorus
content and this percentage figure was the highest in soybean and the lowest in
mung bean. In vitro protein digestibility (IVPD) of
pigeonpea and chickpea genotypes varied from 60.4 to 74.4 percent and 65.3 to
79.4 percent, respectively. The IVPD
values of genotypes of mung bean, urd bean and soybean ranged from 67.2 to 72.2
percent, 55.7 to 63.3 percent and 62.7 to 71.6 percent, respectively.
— There was a significant
(-)negative correlation
between phytic acid and IVPD of these genotypes.
Phytic acid was significantly and positively correlated with protein but
the magnitude of correlation was very low in chickpea and pigeonpea. Results indicate that the genotypes of pulses
with low phytic acid content could be identified and used in breeding program
to improve their nutritive value and utilization.
Cognitive function, see … Iron absorption … http://www.soyonlineservice.co.nz/articles/iron.htm
.
Copper bioavailability … http://www.soyonlineservice.co.nz/articles/Copper.htm
.
Is significantly lower in
rhesus monkeys fed low-phytate soy formula from
1999 “Effect of
reducing the phytate content and of partially hydrolyzing the protein in soy
formula on zinc and copper absorption and status in infant rhesus monkeys and
rat pups,” – Lönnerdal B.,
Jayawickrama L., Lien E.L., Am J Clin Nutr 1999 Mar 69:3 490-6.
— BACKGROUND: Although
soy formulas have been designed to meet the nutrient requirements of human
infants, they also contain phytate, which may negatively affect trace element
absorption.
— OBJECTIVE: We
evaluated the effect of removing phytate on zinc and copper absorption and
status in infant rhesus monkeys and suckling rat pups and evaluated differences
between intact and partially hydrolyzed soy protein.
— DESIGN: In
monkeys, regular and low-hytate soy formulas were fed exclusively for 4 mo and
whole-body absorption and retention of 65Zn, 67Cu, 59Fe, 54Mn, and 47Ca were
determined at different time points with a whole-body counter. Subsequently,
zinc and copper absorption from several human infant formulas and the effect of
phytate concentration were evaluated in suckling rat pups by using 65Zn and
64Cu. Finally, infant rhesus monkeys were fed low-phytate formulas with intact
or hydrolyzed soy protein for 4 mo and plasma zinc and copper were measured
monthly.
— RESULTS: In
the first monkey study, zinc absorption at 1 mo was higher from low-phytate soy
formula (36%) than from regular soy formula (22%), whereas there was no
significant difference between groups in the absorption of other minerals.
Plasma copper was significantly lower in monkeys fed low-phytate soy formula
from 2 to 4 mo. In rat pups, zinc absorption was significantly higher from
low-phytate soy formula (78%) than from regular soy formula (51%) and
hydrolysis of the protein had no significant effect. Phytate content or protein
hydrolysis did not significantly affect copper absorption. In the second monkey
study, plasma copper concentrations were highest in monkeys fed low-phytate,
hydrolyzed-protein soy formula.
— CONCLUSION:
Reducing the phytate content and partially hydrolyzing the protein in soy
formula had a beneficial effect on zinc and copper absorption and status in
infant rhesus monkeys. ... / 88
- 88 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
Iron absorption … http://www.soyonlineservice.co.nz/articles/iron.htm
… (Cognitive Function)
In infants is approximately
doubled by the removal of phytate from soy formula; a similar effect is
observed by doubling the ascorbic acid content of a soy formula.
i i i , i i i , i i i , i i - Also see ... Frying
the Brain With Soy ... page 63
1989 “Search for
nutritional confounding factors in the relationship between iron deficiency
& brain function,” – Hallberg L.,
Am J Clin Nutr 1989 Sep 50:3 Suppl 598-604; discussion 604-6.
— This paper on confounding factors in the relationship between iron
deficiency and brain function is mainly limited to nutritional factors, primarily factors that can contribute to
the development of iron deficiency and that may have an independent direct
action on brain function.
— Three theoretically possible confounders were found in a
systematic search for dietary factors:
1) low intake of ascorbic acid,
2) excess of phytates, and
3) increased absorption of lead.
— Ascorbic acid
has a marked effect on the bioavailability of dietary iron and is also known to directly influence
various metabolic processes in the brain.
— Phytates inhibit the absorption not only of iron but also
of zinc. An iron deficiency may thus be accompanied by
a zinc deficiency which may affect mental performance.
— A state of iron deficiency may increase the absorption of lead
from the diet, which in turn may affect brain function.
1992 “Soy protein,
phytate, and iron absorption in humans,” – Hurrell
R.F., Juillerat M.A., Reddy M.B., and others,
Am J Clin Nutr 1992 Sep 56:3 573-8.
— The effect of reducing
the phytate in soy-protein isolates on nonheme-iron absorption was examined in 32 human subjects. Iron
absorption was measured by using an extrinsic radioiron label in liquid-formula
meals containing hydrolyzed corn starch, corn oil, and either egg white or one
of a series of soy-protein isolates with different phytate contents. Iron
absorption increased four- to fivefold when phytic acid was reduced from its
native amount of 4.9-8.4 to less than 0.01 mg/g of isolate. Even relatively small quantities of
residual phytate were strongly inhibitory and phytic acid had to be reduced to
less than 0.3 mg/g of isolate (corresponding to less than 10 mg phytic
acid/meal) before a meaningful increase in iron absorption was observed. However,
even after removal of virtually all the phytic acid, iron absorption from the
soy-protein meal was still only half that of the egg white control.
— It is concluded that phytic acid is a major inhibitory factor of
iron absorption in soy-protein isolates but that other factors contribute to
the poor bioavailability of iron from these products.
... / 89
- 89 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
Iron absorption ... cont.
1994 “Iron
bioavailability studied in infants: the influence of phytic acid and ascorbic
acid in infant formulas based on soy isolate,” – Davidsson L., Galan P., Kastenmayer P., and others,
Pediatr Res 1994 Dec 36:6 816-22.
— The influence of phytic
acid and ascorbic acid content of soy formula on iron (Fe) bioavailability was investigated in infants by analysis
of the incorporation of stable isotopes of Fe into red blood cells 14 d after
administration using a double stable isotope technique. Paired comparisons were
made with each infant acting as his or her own control. The geometric mean
fractional Fe incorporation into red blood cells increased from 5.5 to 6.8% (p
< 0.05) when soy formula with the native content of phytic acid was compared
with a 83% dephytinized formula. A more pronounced effect was shown with soy
formula containing no phytic acid; the mean fractional Fe incorporation
increased from 3.9 (native phytic acid) to 8.7% (zero phytic acid; p <
0.001). A significant (p < 0.01) effect was also demonstrated when the
Fe:ascorbic acid molar ratio in the native phytate-containing formula was increased
from 1:2.1 to 1:4.2; mean fractional Fe incorporation increased from 5.9 to
9.6% .
— These results demonstrate that the Fe bioavailability from soy-based
infant formulas can be similarly increased by either removing phytic acid or
increasing the ascorbic acid content.
1998 “A comparison
of iron absorption in adults and infants consuming identical infant formulas,”
– Hurrell R.F., Davidsson L., and
others, Br
J Nutr 1998 Jan 79:1 31-6
— Fe absorption was estimated
in adults and infants from the erythrocyte incorporation of Fe isotopes added
to infant formula. Fe absorption was measured in adults using radioisotopes,
and in infants with a stable-isotope technique. In adults, the geometric mean
Fe absorption from a ready-to-feed soya formula with its native phytic acid
content was 2.4%. This increased to 6.0% (P < 0.05) after almost complete
dephytinization. In infants, mean Fe absorption values were 3.9 and 8.7%
respectively from the same products (P < 0.05). In adults, mean Fe
absorption from a spray-dried soya formula containing 110 mg ascorbic acid/l
was 4.1%, increasing to 5.3% (P < 0.05) when ascorbic acid was doubled to
220 mg/l. In infants, mean Fe absorption values were 5.7 and 9.5% (P < 0.05)
from the same products. Mean Fe absorption from a milk-based formula was 6.5%
in adults compared with 6.7% in infants. All meals in the adult and infant
studies were fed using an identical meal size of 217 g.
— Increasing the meal size
threefold in adults did not change fractional Fe absorption. Mean Fe absorption
values for each meal were lower in adults than in infants but the relative
inhibitory effect of phytic acid and the enhancing effect of ascorbic acid were
similar.
— We conclude that Fe absorption studies in adults can be
used to assess the influence of enhancers and inhibitors of Fe absorption in
infant formulas fed to infants. Further studies, however, are required to
extend these findings to weaning foods and complete meals.
... / 90
- 90 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
Zinc
bioavailability and absorption … http://www.soyonlineservice.co.nz/articles/Zinc.htm
.
— Zinc from soy formulas is also reduced by phytate. In rhesus monkeys, zinc
absorption was ...
— 2.0 times greater from monkey milk compared with soy formula,
— 2.2 times greater from
whey-predominant formula
compared with soy formula, and
— 1.7 times greater from casein-predominant formula compared with soy formula.
— Zinc absorption from dephytinized soy formula was approximately the
same as that from casein-predominant formula.
— Soybeans are high in phytic acid, present in the bran or hulls of all
seeds. It's a substance that can block
the uptake of the essential minerals ... calcium ... magnesium ... copper ...
iron ... and especially zinc - in the intestinal tract.
Phytates found in soy products interfere with zinc absorption
more completely than with other minerals.
— Zinc
is called the intelligence mineral because it is needed for
optimal development and functioning of the brain
and nervous system. Zinc plays a role in
... (1.)
protein synthesis and collagen formation
... (2.)
it is involved in the blood-sugar control mechanism and thus protects against diabetes
... (3.)
it is needed for a healthy reproductive system
... (4.)
it is a key component in numerous vital enzymes and plays a key
role in the immune system,
( see ... http://www.mercola.com/article/soy/avoid_soy.htm
... “Newest Research On Why You
Should Avoid Soy”, Apr.9, 2000 ).
; i ;
; i ; --- Vegetarians
who consume tofu & bean curd as a substitute
for meat & dairy products -risk-
severe mineral deficiencies
See -- Malnutrition
... from ... False Nutritional Beliefs … pages
60, 72, 77, and Vitamin B-12 Deficiency pages 93 to 95.
; i ;
i i i , i i i , i i i , i i i - Lower Zinc absorption,
also see... Frying
the Brain With Soy ... page 63
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3559747&dopt=Abstract
.
1987 “Absorption of
zinc from soy protein meals in humans,” – Sandström
B., Kivistö B., Cederblad A., J Nutr 1987 Feb 117:2 321-7.
— absorption of zinc from
soy protein-containing meals was studied in healthy human subjects by means of
extrinsic labelling with 65Zn and whole body counting. Three types of soy
protein, a soy flour, a soy concentrate and a soy isolate, were used in two
types of meals: one consisting of rice and meat sauce and the other of white or
whole-meal bread. Thirty and 100% of the protein of the meat sauce and 50% of
the protein of bread was replaced with the soy protein products. Replacement of 30% of the protein in
meat sauce had a marginal effect on the percentage absorption of zinc, whereas
the absolute amount of zinc absorbed was lower due to lower zinc content
in soy products than in meat.
— total replacement of the meat protein (with soy), a significantly
lower percentage and absolute absorption of zinc was observed.
— A lower absorption of zinc was observed when soy protein
was added to white bread.
The absorption of zinc from the whole-meal bread was low and did not change
when 50% of the flour protein was replaced by soy protein.
— We conclude that the effect of soy protein on zinc
absorption depends on the degree of replacement, the phytic acid and zinc
content of the soy product and the protein content of the meal.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no soy … or
… contains no soy ingredients
Pet Food, farm animal foods ... / 91
- 91 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
Zinc bioavailability
& absorption ...
continued
Phytates found in soy products interfere with zinc absorption
more completely than with other minerals.
i i i , i i i , i i i , i i i -
1988 “Effect of
phytate removal on zinc (Zn) absorption from soy formula,” – Lönnerdal B., Bell J.G., Hendrickx A.G.,
and others., Am
J Clin Nutr 1988 Nov 48:5 1301-6.
— Low zinc bioavailability
from soy formula may be the result of the formula's phytate content. We
assessed the effect of phytate removal from soy formula on Zn absorption using
infant rhesus monkeys and suckling rat pups as animal models. Zn absorption in
monkeys, as determined by whole-body counting, was 65% from human milk, 54%
from monkey milk, 60% from whey-predominant formula, 46% from
casein-predominant formula, and only 27% from conventional soy formula (0.621
mmol phytate/L). In contrast, Zn absorption from dephytinized soy formula
(0.067 mmol phytate/L) was 45%. In suckling rats, Zn absorption from
conventional soy formula was only 16% vs 47% from dephytinized soy formula.
— Phytate concentration in a variety of experimental soy
formulas was inversely correlated to Zn absorption.
— These results suggest that the low bioavailability of Zn from soy
formula is a function of its phytate concentration and can be overcome by
the removal of phytate.
Soy formulas are typically over-supplemented with minerals and
vitamins to account for the deficiencies caused by phytate, but it is evident
that this does not take care of the problems. Removal of phytate
from soy formulas is altogether a better solution but manufactures have not
shown any inclination do this. Why not ??.
Phytate removal will cost $$$ and it seems to us that soy formula
manufacturers consider economics to be more important than the well being of
infants.
* *
*
Manganese absorption … http://www.soyonlineservice.co.nz/articles/Mang.htm
.
Is also doubled by the removal
of phytate from soy formula, but increasing the ascorbic acid content of a soy
formula containing the native amount of phytic acid did not improve manganese
absorption.
1995 “Manganese absorption
in humans: the effect of phytic acid and ascorbic acid in soy formula,” – Davidsson L., Almgren A., and others,
Am J Clin Nutr 1995 Nov 62:5 984-7.
— The absorption of manganese from soy formula was studied in adult
volunteers by extrinsic
labeling of test meals with 54Mn, followed by whole-body retention measurements
for approximately 30 d after intake. Eight subjects participated twice in each
of the two studies, acting as his or her own control. Soy formula containing
the native content of phytic acid was compared with a similar dephytinized
formula: geometric mean manganese absorption increased 2.3-fold from 0.7%
(range: 0.2-1.1%) to 1.6% (range: 1.0-7.2%) (P < 0.01) with the dephytinized
formula. In addition, the effect of the ascorbic acid content of the phytic
acid-containing formula was investigated. Manganese absorption was not
influenced by an increase in the ascorbic acid from 625 mumol/L (110 mg/L) to
1250 mumol/L (220 mg/L): the geometric mean manganese absorption was 0.6%
(range: 0.3-1.0%) and 0.6% (range: 0.3-1.1%), respectively.
— In conclusion, fractional manganese absorption was
approximately doubled by the dephytinization of soy formula but was not
influenced by an increase in the ascorbic acid content of a soy formula
containing the native amount of phytic acid.
... / 92
- 92 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Phytates
Continued
Manganese
; i ;
The
soybean plant has the ability to absorb manganese from the soil and concentrate
it to an extent that soy-based infant formulas can contain as much as 200 times
the level of manganese found in natural breast milk. In
babies, excess manganese that cannot be metabolised is stored in body organs.
Around eight percent of the excess manganese in the diet is stored in the brain in
close proximity to the dopamine-bearing neurons responsible, in part, for
adolescent neurological development. The implications are that the one in 8
infants raised on soy formula during the first 6 months of life may be at risk
of brain and behavioral disorders that don’t become evident
until adolescence.
i i i , i i i , i i i , i i - Also see ... “Frying the Brain With Soy”
... page 63.
The following
3 links discuss the issue of manganese toxicity further.
Is soy-based
infant formula brain damaging ? … http://www.soyonlineservice.co.nz/articles/goodman.htm
. Press
Release, by David Goodman, Ph.D.
— For eighteen years, newborn babies have been fed by infant formula high in the toxic
metal manganese. Common sense teaches that a brain-damaging substance cannot be fed by bottle to our
most vulnerable citizens. Yet research ongoing for a decade at two
— This week's INSIGHT MAGAZINE ONLINE ( www.insightmag.com
) in a special report by David Goodman affirms that the soy infant formula
currently on shelves permits an estimated safe manganese dose of 0.6 mgs. about
120 times the amount found in mother's milk. Excess manganese that the baby
cannot metabolize is stored in body organs, about eight percent in the brain, in
proximity to dopamine-bearing neurons responsible, in part, for adolescent
neurological development.
— Under the direction of Carl Keen, Ph.D. and Bo Lonnerdahl, Ph.D. at UC Davis and Frank
Crinella, Ph.D. and Louis Gottschalk, MD, Ph.D. at UC Irvine, UC professors
have tracked migration of manganese from the digestive track to the brain, in
particular to nerve cells in the basal ganglia bearing the neurotransmitter
dopamine. Evidence for damage to these critical basal ganglia cells active
during adolescence in rats was reported at a Fall 2000 conference at UCI by Dr.
Francis Crinella and Trin Tranh, has been replicated this month at the UC Davis
laboratories.
— The implications are that the one of eight infants during
the first six months of life given soy formula may be at risk for brain
and behavioral disorders not evident until adolescence, a charge denied by the
soy industry. Highly suggestive, the results of brain damage from “Soy infant formula” cannot yet be accepted as applicable to
human infants until further lab studies are carried out in the laboratory on
primates, and epidemiological studies on human children. Nonetheless, the
findings remain provocative and should be widely discussed, especially since thousands of poor mothers receive
soy formula from the government-funded WIC program.
How
Safe is Soy Infant Formula ... http://www.mercola.com/2001/jun/13/soy_formula.htm
... Mercola, June 13, 2001, and
the “Parkinson’s Disease - Manganese - Soy Infant Formula” connection, June 2001 Press Release at ...
http://www.insightmag.com/main.cfm/include/detail/storyid/161117.html
.
... / 93
- 93 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Continued
Vitamin B-12
Deficiency
Vitamin
B 12 deficiency has been recognized as a serious result of soy consumption for
many years. For instance ... this issue is discussed and
examined in the following 2 abstracts ...
1974 “Biological and
Physiological Factors in Soybeans',” – JJ
Rackis, J. Am. Oil Chemists Soc, 1974 Jan; pp 161.
1994 “Implications of
Anti-Nutritional Components in Soybean Foods in Soybean,” – Irvin E Liener.,
examines this issue in 1994 in Critical Reviews in Food Science and Nutrition.
There is a simple
explanation of some of the physical effects that can result fromVitamin B-12
deficiency ... see ... http://www.mercola.com/2002/jul/17/vegan_risk.htm Mercola
Vegans Deficient
in Nutrients
http://www.mercola.com/2002/jul/17/vegan_risk.htm
Veganism is an extreme form of
vegetarianism. Because vegans shun all
animal products, such as meat, fish, and eggs, they may get too little of some
nutrients found in meat and dairy products, such as calcium and vitamin B-12.
Such deficiencies are of particular
concern when it comes to growing teens. The dietary habits of the vegans varied
considerably and did not comply with the average requirements for some
essential nutrients.
Specifically,
the researchers report that vegans had dietary intakes lower than the average
requirements of ... Riboflavin (vitamin B-2) ... Vitamin B-12 ...Vitamin D ...
Calcium ... Selenium.
Even
after the researchers included dietary supplements in their analysis,
the vegans' intake of calcium and selenium remained low. American
Journal of Clinical Nutrition , July
2002;76:100-106,
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12081822&dopt=Abstract
... Dietary intake and nutritional
status of young vegans and omnivores in
2002 “Dietary intake
and nutritional status of young vegans and omnivores in
— CONCLUSION: The dietary habits of the vegans varied
considerably and did not comply with the average requirements for some
essential nutrients.
American
Journal of Clinical Nutrition July 2002;76:100-106
Continued
…
... / 94
- 94 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Continued
Vitamin B-12 Deficiency
Continued
Vitamin B-12
deficiency
Vegans Deficient
in Nutrients
http://www.mercola.com/2002/jul/17/vegan_risk.htm
American
Journal of Clinical Nutrition July 2002;76:100-106
..............................................................................................................................................................................................................
DR. MERCOLA'S COMMENT:
This
study echoes one published last year
, http://www.mercola.com/2001/dec/29/vegetarian.htm
Dangers of a Vegetarian Diet in Teens.
Of
the many nutrients vegans lack, vitamin B12 is the most significant because it
can have permanent neurological complications and even result in blindness ,
i i i , i i i , i i i , i i - Also see ... “Frying the Brain With Soy” ... page 63
http://www.mercola.com/2000/mar/26/vegetarians_blindness.htm Strict Vegetarians Can Develop Blindness
and Brain Damage ...
Contrary
to what many vegetarians believe, vitamin B12 is not absorbed very well, if at
all, from plant sources ,
http://www.mercola.com/2002/jan/26/vegetarianism_myths_02.htm You Can't Get All the Vitamin B12 You Need
From Plant Sources, By Stephen Byrnes, PhD, RNCP, Part 2 of 15.
Previous studies have consistently shown
low B12 levels in vegetarians
and vegans because they do not eat meat and other animal by products. http://www.mercola.com/2000/nov/5/vegetarian_homocysteine.htm
Vegetarians and Vegans Have Elevated Homocysteine Levels
For further information please review the
comprehensive vitamin B12 page http://www.mercola.com/2002/jan/30/vitamin_b12.htm Vitamin
B12: Are You Getting It ?.
These studies do not document some of the
major dangers with choosing to be a vegetarian. For those of you who have a
teenage vegetarian or who are health care practitioners treating these
individuals, this is very important information. You can view the list below
for that information.
One clearly needs to be sensitive to the
fact that a teenager showing sudden changes in their eating patterns may have
an eating disorder and would benefit from an effective intervention. My current
recommendation for an intervention for an eating disorder would be EFT. http://www.mercola.com/article/eft_videos.htm Learn
the Secrets of a Powerful Healing Tool to Transform Your Health
... / 95
- 95 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Continued
Vitamin B-12 Deficiency
Continued
Vitamin B-12
deficiency
Vegans Deficient
in Nutrients
http://www.mercola.com/2002/jul/17/vegan_risk.htm
DR. MERCOLA'S
COMMENT
Continued
You can find EFT practitioners on the Gary
Craig's EFT
Referral page , to EFT practitioners
http://www.emofree.com/Practitioners/referralMain.asp or you
can use my free EFT manual ,
http://www.mercola.com/forms/eftcourse.htm
EFT Manual: The Basic Steps to Your Emotional Freedom, to start the process.
If you are a health care practitioner and
are interested in attending one of the top energy training events of 2002, you will want to be certain to come to
Related Articles:
Vegetarian Diet In Pregnancy Linked To
Birth Defect ... http://www.mercola.com/2000/feb/6/vegetarian_pregnancy.htm
,
The Myths of Vegetarianism ... http://www.mercola.com/2000/apr/2/vegetarian_myths.htm
,
Is Being a Vegetarian Part of Living
Healthy and Longer ?. ... http://www.mercola.com/2001/jul/21/vegetarian.htm
,
Vegetarian Diet May Increase Alzheimer's
Risk ... http://www.mercola.com/2001/may/19/alzheimers.htm
,
Vegetarian Diet Can Cause Repeat
Miscarriages ... http://www.mercola.com/2001/may/12/vitamin_b12.htm
,
Dangers of a Vegetarian Diet in Teens
... http://www.mercola.com/2001/dec/29/vegetarian.htm
.
*** *** *** ***
*** *** *** *** *** *** *** *** *** ***
Guilty of
manslaughter ??.
; i ;
If the
at ... http://www.nzherald.co.nz/storydisplay.cfm?thesection=news&thesubsection=&storyID=2046794
, and,
at ... http://www.nzherald.co.nz/storydisplay.cfm?thesection=news&thesubsection=&storyID=2045066
.
...
/ 96
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Osteoporosis and
Soy Abstracts
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Continued
Other Toxins
. http://www.soyonlineservice.co.nz/03toxins.htm
.
Continued
Letter
to FDA CONSUMER magazine, Aug 2000 ... http://www.fda.gov/fdac/departs/2000/400_ltrs.html
Comment
below on the FDA Consumer article by William Jarvis, Ph.D. FDA
Consumer article on soy spoke of the possible risks of plant estrogens, but
made no mention of the 1980 research, below, on carcinogenic effects of
protease inhibitors found in soy.
i i i , i i i , i i i , i i i - Cancer of the pancreas.
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7192012
.
1980 “The effects of
long-term feeding of soya flour on the rat pancreas,” — McGuinness
E.E, Morgan R.G., Levison D.A. and others, Scandinavian Journal of Gastroenterology, 1980; 15:497-502
; i ; —
Pancreatic cancer
— Rats were fed raw and heated soya flour for up to 2 years.
— The rats fed raw soya flour all developed pancreatic hypertrophy
and hyperplastic and adenomatous nodules. Four of 26 rats fed raw soya
flour continuously and 1 of 5 rats fed raw soya flour for 2 days each week
developed pancreatic cancer.
— Preheating the soya flour seemed to protect against the pancreatic
hyperplastic and neoplastic changes.
— But long periods of heat and pressure also required (130 degrees Celsius) to deactivate
the carcinogenic trypsin inhibitors in soya flour denatures the soy proteins to
the point that they become virtually useless.
; i ; —
Then one either chooses less heating, resulting in more surviving trypsin inhibitors, or more
heating, resulting in useless protein. William Jarvis,
Ph.D., Department of Health Promotion and Education, Loma Linda
University, Loma Linda, California, USA.
i i i , i i i , i i i , i i i , (+) i i i - Also see page 2.
-
http://www.soyonlineservice.co.nz/Refs/Soyatox.htm
…
1994 “Purification
and physicochemical characterization of soyatoxin, a novel toxic protein
isolated from soybeans (Glycine max),” – Vasconcelos
I.M., Trentim A., Carlini C.R,, and others,. Arch Biochem Biophys 1994 Aug 1 312:2 357-66, Depart. Of
Biochemistry & Molecular Biology, Unversidade Federal do Ceara,
— Physicochemical
characterization and biological properties of a new toxic protein
isolated from soybeans
(Glycine max) is reported. The purification procedure consisted basically of
ammonium sulfate fractionation, ion exchange, and affinity chromatographies,
the latter being used for the removal of the seed's lectin and of its trypsin
inhibitor. The highly purified protein, designated soya-toxin, is a single
chain acidic protein (pI 4.4-4.6) of 21 kDa, dependent on reduced thiol groups
to maintain its solubility and biological activities. The toxin is a
metallo-protein containing iron, calcium, zinc, and magnesium. Soya-toxin is
highly toxic to mice (LD50 7-8 mg/kg mouse body wt upon intraperitoneal
injection).
— It produces dyspnoea, tonic-clonic convulsions, and flaccid
paralysis prior to Death of intraperitoneally injected mice. Furthermore, soya-toxin is
immunologically related to another toxic protein (canatoxin), isolated from
Canavalia ensiformis seeds, which is distinct from soya-toxin in containing 18
x 10 kDa noncovalently bound subunits.
— Some biological properties including acute intraperitoneal
toxicity, canatoxin-like ... immunoreactivity ... hemagglutination ... trypsin
inhibitory activity ... induction of platelet release reaction ... and
aggregation displayed by soya-toxin were studied & used to distinguish
soya-toxin from soybean lectin and trypsin inhibitors.
*
* *
... /
97
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
To
protect yourself and the ones you ♥ Love, be sure to read the “ingredient labels”
on all of the foods you buy & just switch
brands as & when necessary.
Also, “especially” if you have cancer,
be very, very careful about eating in “Restaurants”, “Hotels”, at
“parties” and in “Hospitals”, as they do not list the ingredients
in their foods.
.
.
; i ;
Be
careful … be careful !!. … be careful I said …
be careful !!. … “Vegetable oil”
has not been real vegetable oil, that is, actually made from a variety of vegetables, NOT including soy, since the early 1970’s. Since then - till now, courtesy of Monsanto, it has been and still is either
“Soy” or “Canola” or both, and it rarely includes cottonseed,
peanut, or palm oil. ( Notice,
cottonseed, peanut and palm are not vegetables, but they are referred to as
vegetables on food ingredient lists )
See Pages 8 and 24 for – “Safe Alternatives”
P.S. Check your vitamin supplements. Most “Vitamin E”
comes in a “Soy
based carrier oil”. See pages 3, 12, 18, 98, 121, 124.
Soy is also put in ... vitamins & mineral pills as fillers and
binders … prescription medications ... dairy products ... soft drinks … processed
foods ... ground beef ... women’s make-up an personal care products ... fruit
juice ( as an emulsifier to blend and suspend ingredients for visual esthetics )
... pet foods ... etc., etc., etc.
...
/ 98
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Crimes Against
Humanity ... Crimes Against Nature.
Soy Is
Being Used As A Weapon Of Mass Destruction, WMD
This is only some of the
growing body of scientific research available on the many “health hazards” of soy.
Think about all of those ignored “side-effects”
listed on page one. Now, you
can begin to start counting the number of people, worldwide, likely to be
seriously hurt and/or dying from eating soy simply because of what these people
were told, were “persuaded”
to believe ... “using”
soy is going to help them, even help save their life” ... when in reality,
soy is slowly and “violently killing them”. The US FDA’s “Poisonous Plant Database” ... http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY ... lists Soy, (Flax, Canola) as “poisonous plants,”
and recommends that if you are injured to contact your local “Poison
Control Center” in your area, (at ... http://www.aapcc.org/.),
or 911.
With reference
to “The Precautionary Principle”, “Humanitarianism”, basic human “ethics”, and on the
bases of the
“Preponderance of Evidence” of
the information and the scientific history presented in this research paper, I
charge the “accused”,
( being the Soy Industry, the Food Industry and many Government
agencies around the world ), in accordance with the internationally accepted
legal terms as defined here by BLACK’S LAW DICTIONARY, 6th
Edition, 1990, of inflecting untold,
incalculable, “unimaginable”
and needless pain, suffering, agony and torture onto innocent
people around the world. The scientific
history presented here reveals and illustrates the means by which the accused
has perpetrated this unimaginable pain and needless suffering as a direct
result of their actions, which include, but are not limited to ... “Willful
Misconduct” ... “Misrepresentation” ... “Conspiracy” ... “Criminal Conspiracy”
... “Conspiracy of Silence” ... “Quasi Crimes” ... “Criminal Homicide” ...
“Criminal Gross Negligence”-(also see “Color of Law and Color of
Office”) ... “Fraudulent Concealment” ... “Fraudulent Intent”. All of these actions, past and present, is
having the direct result of “Defrauding”
people of their “Wealth”,
which I define as, but not limited to, our:
1.)
Physical Health and Financial wealth,
2.)
Ability to pursue happiness and Peace of mind,
3.)
Life and
4.) The continued enjoyment of family, friends
and of all life forms on earth.
Social Justice … Socrates ... ( 469 - 399 BC ) ... http://www.philosophypages.com/ph/socr.htm
,
Socrates
said about … “Courage” … “Examine your thoughts, statements and
actions by pursuing their implications, on the assumption that if they are
true, they would not lead to false consequences,” and
about …
“Humanitarian
Action” … “Choose wisdom so that society is
incapable of doing wrong.”
The
“Humanitarian” … adj. 1.) Having
regard to the interests of all mankind; broadly philanthropic.
2.) Pertaining to ethical or theological
humanitarianism.
“Philanthropy” … noun 1.) Love
of mankind, especially as manifested in deeds of practical beneficence.
2.) A philanthropic action, work, institution or
the like.
“Ethics” … n. pl. 1.) The principles of morality, including
both the science of the good and the science of right.
*
* * ; $
; *
* *
In a very interesting article on Cancer in
the Vancouver Sun News paper, in May 2004, here in Van. BC, it said that ... with 1 in 3 women and 1 in 2 men currently
dying from cancer each year, it is now estimated that dying from cancer will be
the leading cause of death by the year 2020 . Adding more soy to our food supply will only increase the
yearly cancer deaths, along with all of its unimaginable pain, suffering, and
heartache. Since soy also causes cancer
& cancer cells to grow, you can see no one is safe from the very many known, ignored, denied, harmful and
sometimes deadly
side-effects of eating soy. It is very
easy to conclude that if soy is recommend to anyone, many for people will also
be faced with cancer and a reoccurrence of cancer from eating soy. Recommend soy, a poison, to anyone and you will very likely be giving them an automatic
death sentence, and participating in mass murder. Why do we say this ??. Dr. Samuel Epstein, MD,
founder of the “Cancer Prevention Coalition” and Professor of Environmental and Occupational Medicine at the
School of Public Health, University of Illinois Medical Center, says in the 2003 movie “The Corporation” ... http://www.thecorporation.com/ , and
... http://www.thecorporation.tv/about/
(Synopsis), that ... dying from
chemical poisoning is really no different than if a gun was put to your
head and someone else pulled the trigger. Chemical poisoning is just a little
slower, that’s all ... Murder is still Murder.
... / 99
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“... Over the past few decades, the USA and Canadian
farmers have grown more and more Rapeseed
, Canola, {and Soy}, for use by food
manufacturers world wide. They ship it
for use in thousands of processed foods, ( and also in our vitamins &
mineral supplements, and medications as fillers and binders ), with the
blessings of our governments and their watchdog agencies, particularly
the powerful and corrupt FDA. I do say “corrupt” for several reasons, the least of which
are ...
(1.) the FDA
“fast-tracks” for
approval costly, proven toxic and sometimes deadly drugs, as well as,
toxic
experimental
drugs for cancer and aids patients, ...
(2.) the FDA allows
“junk foods” to be sold with
multiple ingredients that are “scientifically proven” to
cause
a variety of serious health hazards to children, included cancer, (some ingredients
banned in Europe), ...
(3.) the FDA knowingly
condons and allows distribution of “regular processed foods” with toxic
and
poisonous canola, soy and other toxic and poisonous ingredients, ...
(4.) all the
while, the FDA is persecuting those selling virtually harmless vitamins & herbs with
scientifically
proven very valuable, and in many cases extremely valuable, health benefits...”
Essence
of above quote on page 74–75 in ... “Healing
Celebrations”, © 2000, by Dr. Leonard G. Horowitz
“... A sad plight in
From
... “Killing Cancer, The Jason Winters
Story”, © 1993,
by Benjamin R. Smythe, Sir Jason Winters
After the 2nd World War, Canada and the U.S.A.
were two countries that signed both the
“Declaration of Helsinki” and the “Nuremberg Code “. These agreements state that countries and
industry will not and can not use people as “Guinea Pigs” … A person can not be experimented
on without the person(s) permission; they “must tell” the person(s)
“in advance” about … “a
reasonable chance of harm” … “A
person has the right to be informed …
to be given the opportunity to CHOOSE” …
so that the person(s) is allowed the right to exercise their free will to
participate or not. ( i.e.: Dr. Nancy Olivieri wins
her legal battle with Apotex Pharmaceutical Company, 1998-2002, Children’s Hospital, Toronto, Ont.).
.
In the case of soy, this research paper clearly documents
scientifically that these international
agreements have been knowingly and willfully violated for over 80
years by the “Participants,” which includes but is not limited to … the mainstream and the natural health food industries-(manufactures,
sellers) … the soy industry and
their industry scientists, Monsanto, DuPont,
Dow, pharmaceutical industry …
merchants-(vitamin companies, retail stores) … publicists-(almost all authors of books on nutrition, food
writers) … US FDA … the advertising media and news media … USDA … the main stream medical system … Naturopaths … the
Alternative Health Care System …
bureaucrats, (in various positions of authority and regulatory authority), in
almost all countries. Because of the
“Participants” actions, the victims can charge them with “Criminal Homicide,” Criminal Gross Negligence, Deceit and Deception through Fraudulent
Intent and Concealment of the many serious health hazards imposed onto the
world population from putting soy in our food supply) . See
pages 101 – 104
...
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“…Imagine having drugs added to our
food which have been scientifically proven to be carcinogenic for at least 40
years and to also cause DNA and chromosome damage for more than
25 years in both humans & in animals. Also, imagine these drugs being
prescribed and administered through our food supply without the individual’s prior
knowledge or understanding of these dangers, or prior consent to be exposed to these
dangers. Now, imagine the entire population in many countries around
the world, including ours, consuming these foods ... with no medical way of
tracking dosage, individual reactions, or harmful side-effects, and, without
any concern for some people’s increased vulnerability from being exposed
to these drugs, such as cancer patients.
Does all this sound a little
crazy ??. Well, I’ll tell yeah,
this is exactly what is happening to us when Soy is added to our food supply. Soy contains the “naturally toxic” ingredients genistein and daidzein which have been scientifically
documented, proven, to be carcinogenic, cause DNA and chromosome damage, and to cause cancer cells to grow. Soy can also cause non-cancerous tumors to turn cancerous …”. Soy does all this and more, as these are only some of the many
health hazards associated with eating soy. To protect your health and
your families health, be sure to read the ingredient labels on all of
the foods you buy. Also,
be very, very careful about eating in “Restaurants” and in “Hospitals”,
as they do not list the ingredients in their foods. Vegetable oil
is no longer vegetable oil ... it’s either “Soy”, or “Canola”, or
both.
Soy acts like fertilizer and
fertilizes, feeds, cancer cells to help them grow.
US FDA’s “Poisonous Plant Database” ... http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY ... lists Soy, as a “poisonous plant,” and it
recommends if you are injured to contact your local “Poison
Control Center” in your area, (at ... http://www.aapcc.org/.),
or 911.
“...
All Truth passes through 3 phases: first
it is ridiculed; next it is violently opposed; and
finally it is accepted as self evident ...”, from
the German philosopher Arthur Schopenhauer, 1788 - 1860.
"...
Money, not truth, drives science – even at the expense of the health and lives
of the nation's citizens ...", by Dr. Phyllis
Mullenix, Ph.D., formerly of Harvard University, Dept. of Neuropathology and
Psychiatry, See ...
http://www.lef.org/fda-museum/8_water/intarticles/fluoride-01-98.html
... Did Government Approve Citizens as
Toxic Waste Sites ??, Are We Being Poisoned ?? ... and it is no mistake !!.
and http://www.whale.to/b/fl2.html.
Einstein said, “...the world is a dangerous place to live in, not because of the people who
are evil, but because of the people who don’t do anything about it...”.
P.S. “The
Truth Marches On” ... Emile Zola
... and “The Dreyfus Affair,” in France, 1894 - 1898 …
at … http://www.georgetown.edu/faculty/guieuj/libproj.htm … http://www.dreyfuscase.com/html/dreyfus_affair.html
, and others
Blacks Law
Dictionary, 6th Edition, 1990
http://www.trufax.org/reports/legal.html
Legal Definitions
While reading the following definitions,
think of the topics ... Aspartame ... Food irradiation ... GMO food ... Vaccinations ... Soy ...
Canola ...Fluoride ... EMF
hazards-(microwaves) ... Pesticides ... etc., etc., etc.
Belief Proof Quasi
Crimes
Conflict
of Interest Positive
Proof Criminal
Homicide
Conspiracy
in Restraint of Trade Informed
Consent Monopoly
Suppressio
Veri, Espressio Falsi Convincing Proof Monopoly Power
Truth Those who control & manipulate others,
Def. Monopolization
Fact Criminal
Conspiracy Negligence
Fraud Color
of Law Preponderance
of evidence
Fraudulent
Concealment Color
of Office Willful
Misconduct
Fraudulent
Intend Criminal Grass Negligence Malicious
Abuse of Legal Process
Deceit Criminal
Behavior
Misrepresentation “Last Train From Gun Hill,” 1959, Kirk
Douglas, Paramount Pictures
... /
101
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Leading
Edge Research: Blacks Legal Definitions
See
Also, Corporate Research Page
Blacks Law Dictionary, 6th
Edition, 1990
Legal
Definitions
http://www.trufax.org/reports/legal.html
Belief: A subjective condition that is a conviction of the truth of a proposition, induced into existence within the mind.
(Note: that belief does not involve
truth, but only the conviction of it).
Conflict of Interest:
Term used in connection with public officials, fiduciaries and their
relationship to matters of private interest or gain to them; a clash between
public interest and the private pecuniary interest of the individual or individuals
concerned; a conflict of interest arise when a person's personal or financial
interest conflicts or appears to conflict with his official responsibility. 18
U.S.C.A. §203 et seq. Examples: An
FDA official takes a job with a company producing a product over whom he has
had regulatory influence; a company official takes a job at the FDA where he or
she is in a position to rule over products created by his former employer or
extensions of products or processes thereof.
Conspiracy in Restraint of Trade: All forms of illegal agreements which have as
their object interference with free flow of commerce and trade.
Suppressio Veri, Expressio Falsi: Suppression of the truth is equivalent to
expression or suggestion of what is false.
Truth:
That which is conformable to the actual state of things. (Note: not subjective)
Fact:
Reality of events or things the actual occurrence or existence of which
is to be determined by evidence. An actual happening in time and space or a
mental or physical event.
Fraud: An
intentional perversion of the truth for the purpose of inducing anotherin
reliance upon it to part with some valuable thing or to surrender a legal
right; a false representation of a matter of fact, whether by words ot conduct,
by false or misleading allegations, or by concealment of that which should have
been disclosed, which deceives and is intended to deceive another so that he
shall act upon it to his legal inquiry; anything calculated to deceive, whether
by a single act or combination, or by suppression of truth, or suggestion of
what is false, whether it be by direct falsehood or innuendo, by speech or
silence, word of mouth, or look or gesture; fraud comprises all acts,
omissions, and concealments involving a branch of legal or equitable duty and
resulting in damage to another.
Fraudulent Concealment: The
hiding or suppression of a material fact or circumstance which the party is
legally or morally bound to disclose, in order to prevent inquiry, escape
investigation, or to mislead or hinder the acquisition of information
disclosing a right of action.
Fraudulent Intent:
Such intent exists where one, either with a view of benefitting oneself
or misleading another into a course of action, makes a representation which one
knows to be false or which one does not believe to be true.
Deceit: A
fraudulent and deceptive misrepresentation, artifice, or device, used by one or
more persons to deceive and trick another, who is ignorant of the true
facts.
http://www.trufax.org/reports/legal.html
.
...
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Blacks Law
Dictionary, 6th Edition, 1990
Legal Definitions
http://www.trufax.org/reports/legal.html
Cont.
Misrepresentation: Any
manifestation by words or other conduct not in accordance with the facts; an
untrue statement of fact; an incorrect or false representation which, if
accepted, leads the mind to an apprehension of a condition other and different
from that which exists.
Proof: The
result or effect of evidence, the means by which a fact is proven.
Positive Proof:
That which establishes the fact in question, as opposed to negative
proof, which establishes the fact by showing that its opposite is not or
cannot be true.
Informed Consent: A
person's agreement to allow something to happen, based on full disclosure of
the facts needed to make the decision intelligently; i.e., knowledge of risks
involved, alternatives, etc.; the general priciple of law embodying the duty to
disclose to another whatever risks might be incurred from a proposed course of
treatment, so that a person, exercising ordinary care for his own welfare, and
faced with a choice of undergoing the proposed treatment, or alternative
treatment, or none at all, may intelligently exercise his judgment by
reasonably balancing the probable or possible risks against the probable or
possible benefits.
Convincing Proof:
Such as is sufficient to establish the proposition beyond reasonable
doubt in an unprejudiced mind. (Note:
a mind is not unprejudiced where a
belief already exists).
(Keep
the following in mind relative to those entities who herein control and manipulate
others):
Criminal Conspiracy: A
combination or confederation between two or more persons, formed for the
purpose of committing, by their joint efforts, some unlawful or criminal act,
or some act which is lawful in itself, but becomes unlawful when done by the
concerted action of the conspirators, or for the purpose of using criminal or
unlawful means to the commission of an act not in itself unlawful. A person is
guilty of conspiracy if that person agrees to aid other persons in the planning
or commission of such crime, or of an attempt or solicitation of such a
crime. A conspiracy may be a
continuing one; actors may
drop out, and others drop in; the details of operation may change from time to
time; the members need not know each other or the part played by others; a
member need not know all the details of the plan or the operation; he must,
however, know the purpose of the conspiracy and agree to become a party to a
plan to effectuate that purpose. A chain-conspiracy
is characterized by different activities carried on with the same subject of
conspiracy in chain-like manner that each conspirator in chain-like manner
performs a separate function which serves in the accomplishment of the overall
conspiracy. A civil conspiracy
is a concert or combination to defraud or cause other injury to person or
property, which results in damage to the person or property. Conspiracy in restraint of trade
describes all forms of illegal agreements such as boycotts, price-fixing, etc.,
which have as their object interference with the free flow of commerce and
trade. One cannot agree or conspire with another who does not agree or conspire
with him.
Color of Law:
Misuse of power, possessed by virtue of law, and made possible only
because the wrongdoer is clothed with authority of State. Misuse of power by an
official because the person is an official. Unlawful acts under color of law
would not have occurred but for the fact that the person committing them was an
official then, and there exercising power outside the bounds of lawful
authority.
Color of Office:
Pretense of official right to do an act made by one has no such right
confered by any authority.
http://www.trufax.org/reports/legal.html
.
...
/ 103
- 103 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Blacks Law
Dictionary, 6th Edition, 1990
Legal Definitions
http://www.trufax.org/reports/legal.html
Cont.
Criminal Gross Negligence:
Negligence that is accompanied by acts of commission, or omission of a
wanton or willful nature, showing a reckless or indifferent disregard of the
rights of others, under circumstances reasonably calculated to produce injury,
or which make it probable that injury will be occassioned, and the offender
knows or is charged with knowledge of the probable results of his acts.
Criminal Behavior: Conduct which causes
any social harm which is defined and made punishable by law, presuming the law
exists which covers the action.
Quasi Crimes: All
offenses not crimes or misdemeanors, but that are in the nature of crimes; a
class of offenses against the public which have not been declared crimes, but
wrongs against the general or local public which should be punished by
penalties.
Criminal Homicide:
Criminal homicide constitutes murder when it is committed purposely or
knowingly, or committed recklessly under circumstances manifesting extreme
indifference to the value of human life.
Malicious Abuse of Legal Process: Perversion of court process to accomplish
some end which the process was not designed to accomplish, and does not arise
from the regular use of process, even with ulterior motives. Intent is to
secure ends other than those intended by law through willfull application of
court process.
Monopoly: A
privilege or peculiar advantage vested in one or more persons or companies,
consisting in the exclusive right (or power) to carry on a particular business
or trade, manufacture a particular article, or control the sale of the whole
supply of a particular commodity. A form of market structure in which one or
only a few firms dominate the total sales of a product or service; the two main
elements of the Sherman Antitrust Act are: possession of monopoly power and
willful acquisition or maintenance of that power, as distinguished from growth
or development as a consequence of a superior product, business acumen, or
historic accident.
Monopoly Power:
That which must exist to establish a violation of the Sherman Anti-Trust
Act. The power to fix prices, to exclude competitors, or to control the market
in the geographical area in question.
Monopolization: It
is monopolization for persons to combine or conspire to acquire or maintain power
to exclude competitors from any part of trade or commerce, provided they also
have such power that they are able, as group, to exclude actual or potential
competition, and provided they have intent and purpose to exercise that power.
Negligence: Omission
which a reasonable person, guided by ordinary considerations which ordinarily
regulate human affairs, would do, or the doing of something which a reasonable
and prudent person would not do; conduct which falls below the standard
established by law for the protection of others from unreasonable risk of harm.
Preponderance of evidence:
Evidence which is of greater weight or more convincing that the evidence
which is offered in opposition to it; it may not be determined by the number of
witnesses, but by the greater weight of all evidence, the opportunity for
knowledge, information possessed.
Willful Misconduct:
Conduct committed with an intentional or reckless disregard for the
safety of others, or with an intentional disregard of a duty necessary to the
safety of another's property.
http://www.trufax.org/reports/legal.html
End of Definitions
...........................................................................................................
...
/ 104
- 104 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“The
Corporation”
http://www.thecorporation.tv/splash
A documentary film delves into the “nature”
of an Institution
Feature documentary by Mark Achbar,
Jennifer Abbott and Joel Bakan
Film release Van., BC.,
Synopsis of the film at ... http://www.thecorporation.tv/synopsis.php , http://www.thecorporation.tv/about/
.
Based on the book by Joel Bakan
“The Corporation - The Pathological
Pursuit of Profit & Power”
http://gallery.bcentral.com/Gallery/ProductListing.aspx?GID=5059307&Dept=358159&searchString=&page=1
.
Joel Bakan, Vancouver University of BC law professor urges restoration of corporation's original
purpose, to serve the public interest,
calls for re-establishment of democratic control over the institution.
Concrete, pragmatic, realistic reforms are proposed
Personality
Diagnostic Checklist
WHO, World Health Organization ICD - 10
Manual of Mental Disorders DSM - IV
In law, the corporation is a “person” ... But,
what kind of person is it ??.
Subject: The Corporation, ( and its
distinguishable characteristics )
U
Callous unconcern for the feelings of others. U
Deceitfulness: repeated lying and conning others for profit
U
Incapacity to maintain enduring relationships. U
Incapacity to experience guilt.
U
Reckless disregard for the safety of others.
U
Failure to conform to social norms with respect to lawful behaviours.
The
Diagnosis: Psychopath Personality
Disorder
( Also, see pages 17 and 109 –
112 and 119 )
* *
*
The 1958 Delaney Amendment, pcdf
http://www.pcdf.org/meadows/delaney.htm
Essay Sept. 26, 1996.
“... Over centuries we have written
innumerable laws to protect ourselves from each other's foolishness,
negligence, incompetence, or evil. Few
of those laws forbid anything absolutely.
Murder we can get away with, in self-defense or insanity. We can build on flood plains, if we really
want to. The law is strict about robbing
banks, but there are plenty of legal ways to rob the public treasury. Most environmental laws allow us to poison
people just a bit, as long as we claim to create an economic benefit in the
process.
“... But there were until recently two
laws that said flatly No, this you cannot do.
One was the Endangered Species Act, which didn't let you push a creature
into extinction. The other was the
"Delaney amendment," which forbade you from adding to foods anything
that might cause cancer.
“... Hated by industry but loved by
the public, these laws withstood steady attack by lobbyists, until recently.
The Delaney clause, named after Congressman
James Delaney of New York, said, “the Secretary [of the Food and Drug Administration] shall not
approve for use in food any chemical additive found to induce cancer in
man, or, after tests, found to induce cancer in animals.” Not any. Zero, none, nil, zip.
... / 105
- 105 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“... If you tell a lie big enough and keep repeating it, people will eventually come
to believe it ...”
“... The lie can be maintained only for such time as the
State, (or Corporation,
Medical System, or Religion), can shield the
people from the political, economic and/or military consequences of the
lie. It thus becomes vitally important
for the State to use all of its powers to repress dissent, for the truth is the
mortal enemy of the lie, and thus by extension, the truth is the greatest enemy
of the State ...”.
by Joseph Goebbels, German Minister of
Propaganda, 1933 -1945
*** ***
***
... More On Soy’s Fraudulent History
...
Also see pages 4, 5, 6, 7, 18 and 11, as
well as ( 12, 100, 107, 121 )
; i ;
The
original petition submitted by Protein Technologies International, PTI,
requested that the health claim be made for the soy isoflavones, the plant estrogens
found abundantly in soybeans.
Provided with only weak and conflicting proofs that isoflavones lower
cholesterol and besieged by strong
evidence of toxicity and hormone
disruption, the FDA should have thrown out the PTA petition. It had a duty to do so.
Instead,
1998, the FDA took the unprecedented step of
rewriting PTI’s petition
& substituting a claim for soy protein. This
step violated the industry’s own regulations. Then the FDA speeded the
decision-making process by reducing the time in which members of the public
could protest to only 30 days. In doing
so, they disregarded the testimony of ... top scientists at the FDA’s own
National Center of Toxicological Research ... British government researchers (1998)
... and other qualified experts ... all of which were providing strong evidence
of danger from allergens, protease, inhibitors, and other soy components as
well as the plant hormones.
It's
all the more shocking because the FDA never had good evidence of soy’s
cholesterol lowering effect to begin with !. It relied almost entirely on
just one study — a 1995 meta analysis of 29 studies by
James W. Anderson that was sponsored by Protein Technologies International. Then on
P.S.
For next important quote, see middle of pages 18, and 119,
“... The FDA and its employees have legislative immunity and can lie
with no fear of being held accountable, which is what they did in
approving a “health claim” for soy ...”.
Also, the
... / 106
- 106 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to know why you don’t hear about the many health
hazards of Soy ??
These
next 4 stories, (following 4 pages below), provides good examples of just some of
the documented proof of - and the types
of - methods used in the attempted and mostly successful suppression
and cover-up
of the truth;
specifically as it applies to and about the harmful side-effects to human and
animal health of GM foods.
The
same methods of cover-up and suppression of the truth can also be very easily proven with
respect to the cover-up and suppression of the information about the scientific
research on the many harmful side-effects of eating Soy. These 4 examples below
illustrate and show why - 99% - of the research and its information about the
many health hazards of eating soy does not reach the news media or get past the
news media in order to inform the public.
? Freedom Of The
Press ?
http://www.ranknfile-ue.org/untold.html
; i ;
“One
night, probably in 1880,
John Swinton, then the preeminent
“There is no such thing, at this date of
the world’s history, in
There is not one of you who dares to write
your honest opinions, and if you did, you know beforehand that it would never
appear in print. I am paid weekly for
keeping my honest opinion out of the paper I am connected with. Others of you
are paid similar salaries for similar things, and any of you who would be so
foolish as to write honest opinions would be out on the streets looking for
another job. If I allowed my honest
opinions to appear in one issue of my paper, before twenty-four hours my
occupation would be gone.
The business of the journalists is to
destroy the truth, to lie outright, to pervert, to vilify, to fawn at the feet
of mammon, and to sell his country and his race for his daily bread.
You know it and I know it, and what folly
is this toasting an independent press ?.
We are the tools and vassals of rich men
behind the scenes. We are the jumping
jacks, they pull the strings and we dance.
Our talents, our possibilities and our lives are all the property of
other men. We are intellectual
prostitutes.”
******************************************************************************************
(Source: Labor's Untold Story, by Richard
O. Boyer and Herbert M. Morais, published by United Electrical, Radio
and Machine Workers of America, NY, 1955/1979.).
* *
*
.
The weed of crime bears bitter
fruit. Does the soy industry and all of its
supporters really think they’ll all get away with it ??. Do they really think I wouldn’t know ??.
Einstein said, “...the world is a dangerous place to live in, not because of the people who
are evil, but because of the people who don’t do anything about it...”.
...
/ 107
- 107 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to know why you don’t hear about the many health
hazards of Soy ??
This
2001 news research story below from Project Censored,
reporting “The 25 most censored media stories each year,” provides
a clear and undeniable example of the documented proof of the attempted and
mostly successful suppression & cover-up
of the truth about the harmful side-effects to human
and animal health of GM foods. The
same type of cover-up can easily be proven with respect to the information
about the harmful side-effects of eating Soy. This is why 99% of the research & its
information on the many health hazards of eating soy does not reach or get past
the news media in order to inform the public.
“Independent Study Points to Dangers of Genetically Altered
Foods”
(Dismissed by Media
and Biotech Industry)
Hiding The Health Hazards of GMO, (2001)
http://www.projectcensored.org/publications/2001/7.html
Project Censored, “The 25 most censored
media stories each year.”
; i ;
"...
In 1998, Arpad Pusztai, a researcher at Rowett
Research Institute in
"...
The actual process of genetic alteration itself may cause damage to the
mammalian digestive and immune systems.
"...
Pusztai’s study found that rats fed transgenic potatoes (artificially bio-engineered to
include a gene from another species) showed evidence of organ damage, thickening of the small
intestine, & poor brain development.
"...
In August 1998,
Pusztai appeared on the British television program "The World in Action" to report on the findings of his
study. In an attempt to quell the
resulting public furor, Rowett Institute director Mr. Philip James (who had
approved Pusztai's TV appearance) said the research didn't exist. He fired Pusztai, broke up his research team,
seized the data, and halted 6 other similar projects ...".
"...
It came out later that Monsanto, a leading
"...
The research that Mr. Philip James claimed did not exist “showed up”
during an internal audit ...", which then resulted in the further
investigation and publication of this news story.
*
* *
“Meta - Analysis”... http://www.mercola.com/article/soy/avoid_soy.htm ... A meta-analysis
is a review and summary of the results of many clinical studies on the same
subject. The use of meta-analyses to
draw general conclusions has come under sharp criticism by members of the
scientific community. "... Researchers substituting
meta-analysis for more rigorous trials risk making faulty assumptions and
indulging in creative accounting ...", says Sir John Scott, President of
the Royal Society of New
There
is the added temptation for researchers, particularly researchers funded
by a company like Protein Technologies International,
to leave out studies that would prevent the desired conclusions.
Dr Anderson discarded eight studies for various reasons, leaving a remainder of
twenty-nine.
For example, it was a 1994 meta-analysis by Mark Messina, published in Nutrition
and Cancer, that fueled False speculation on soy's
anti-carcinogenic properties. 43. (And yet, this paper
proves that Soy has been known, in the scientific community, to be carcinogenic
for over 40 years, and to cause DNA and Chromosome damage for more than 25
years)
...
/ 108
- 108 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to know why you don’t hear about the many health
hazards of Soy ??
Project Censored
http://www.projectcensored.org/default.html
#2 - Chemical
Companies Profit off of Breast Cancer
Reported in 1999 ... “Story #2 of The Top
25 Censored Media Stories of 1998"
; i ;
“...
In one of the more cynical examples of corporate profit-making ingenuity,
leaders in cancer treatment and information are the same
chemical companies that also produce carcinogenic products.
Breast Cancer Awareness Month, initiated
in 1985 by the chemical conglomerate Imperial Chemical Industries, currently
called Zeneca Pharmaceuticals, reveals an uncomfortably close connection between the
chemical industry and the cancer research establishment. As the controlling sponsor of Breast Cancer Awareness Month (BCAM), Zeneca is able to approve--or veto-any
promotional or informational materials, posters, advertisements, etc. that BCAM
uses. The focus is strictly limited to information regarding early detection
and treatment, with an avoidance of the topic of
prevention. Critics
have begun to question why.
With revenues of $14 billion, Zeneca is
among the world's largest manufacturers of pesticides, plastics, and
pharmaceuticals. Zeneca was instrumental in convincing the FDA to approve
tamoxifen as a Ñprevention" measure to reduce the incidence of breast
cancer in healthy women at risk. However,
World Health Organization's, WHO International Agency for Research on Cancer considers
- tamoxifen - a "probable human carcinogen ".
Sources: RACHEL'S
ENVIRONMENT AND HEALTH WEEKLY, "The Truth About Breast Cancer,"
( i (
The Primary Objective of Project Censored ... is
to explore and publicize the extent of censorship in our society by locating
stories about significant issues of which the public should be aware, but is
not, for one reason or another. Thereby, the project hopes to stimulate
responsible journalists to provide more mass media coverage of those issues and
to encourage the general public to demand mass media coverage of those issues
or to seek information from other sources.
The Essential Issue raised by the project
... is the failure of the
mass media to provide the people with all the information they need to make
informed decisions concerning their own lives and in the voting booth.
Criteria For News Story Nominations
1.) A
censored news story is information that the general
2.) The
news story is timely, on-going, and has implications for a significant number
of residents in the
3.) The
story has clearly defined concepts and is backed up with solid verifiable
documentation.
* * 4.) The
news story has been publicly published, either electronically or in print, in a
circulated newspaper, journal, magazine,
newsletter, or similar publication from either
a foreign or domestic source.
5.) The
news story has direct connections to and implications for people in the
... / 109
- 109 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Want to know why you don’t hear about the many health
hazards of Soy ??
----- Original Message -----
From: Gerald Hernesmaa
To: Lorna Hancock , Health Action Network Society … www.hans.org
Cc: Cathrine Gabriel
Sent:
Subject: [corp-focus] Rotten to the Core ...
Corporate Dishonesty ... officially promoted !! ... taught in
University classes
.
Hi
... Cathrine
From
... Gerald and Deonaa
Hernesmaa
Short
and sweet. Easy and fast reading. Just
sit back, relax and enjoy this one.
Monsanto and the Soy industry is at the top of the list on this one for
sure, along with the mainstream
medical
system, ... As you are enjoying this, also think of scientifically known
hazards ... GMO Foods ...
food
irradiation ... MSG ... Vaccinations ... Fluoride ... Canola ... Soy ...
Mercury in teeth fillings ... etc., etc. ...
Here
are just a couple of colourful highlights from below. This explains what we, HANS, and we the
people,
are up against in a nut shell.
....................................................................................................
; i ;
Rotten
to the Core ... “Dishonesty 'officially' promoted !!,”
Quotes below - from this
website article - below,
“... Frank Easterbrook and Daniel Fischel are University
of Chicago 'law professors' who believe
that, when it comes to making profits, nothing -- not even the law -- should
stand in the way ...
“... both professors at the University of Chicago,
wrote that managers not only may, but should,
violate the rules when it is profitable to do so ...
“... We're talking about fraud, corruption, pollution, price-fixing,
occupational disease, bribery ...",
cancer ... and even death ... and the list goes on ... and on
... and on ... and on ...
“... The Chicago School says these are "externalities" and related fines and penalties should
simply be viewed as the "costs of doing business
..."
……………………………………………………………………….
“Know
your enemy.”
“The Truth Marches On” ...
Emile Zola ... and the Dreyfus Affair, France 1898 ... and author
of
many good books ... http://www.georgetown.edu/faculty/guieuj/libproj.htm
.
Have a nice day,
Gerald
...
/ 110
- 110 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Website
address below is ... http://lists.essential.org/pipermail/corp-focus/2002/000105.html
.
.............................................................................................................................................................................
[corp-focus] Rotten to the Core
Robert Weissman rob@essential.org
Thu, 21 Feb 2002 10:22:37 -0800
Previous
message: [corp-focus]
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.
; i ;
Rotten to the Core
Corporate
"Dishonesty 'Officially' Promoted !."
by Russell Mokhiber and Robert Weissman
Frank
Easterbrook and Daniel Fischel are
when
it comes to making profits, nothing – not even the law
-- should stand in the way.
(For almost two decades, Easterbrook has
also been a federal appeals court judge.)
Twenty years ago, writing about antitrust
crimes in the Michigan Law Review, Easterbrook and Fischel,
then both
professors at the
violate
the rules when it is profitable to do so. And it is clear that they believed that this rule should
apply beyond just antitrust.
In a nutshell, this is the
Under this view, if a Fed Ex truck needs
to double park to make a delivery -- double park. No problem.
Pay
the $20 fine. Just as long as you are
still making money, violate the law.
Or course, when it comes to corporate
crime and violence, we aren't talking about just double parking.
We're
talking about fraud, corruption,
pollution, price-fixing,
occupational disease, and bribery.
Externalities … is an effect of
The
be
viewed as the "costs of doing business." one
set of parties on others
Externalities … http://economics.about.com/cs/economicsglossary/g/externality.htm
. who did not have a choice and
whose interests were not taken
We call these activities crimes, and we
believe society imposes penalties for committing these crimes into account.
to deter and socially sanction those who
would violate society's proscription.
Lawmakers of both parties are shamelessly
portraying Enron and Arthur Andersen as rotten apples,
even though those same lawmakers were just
until recently on the take from both corporations, and doing
the dirty work of defeating laws that
would have governed both.
Continued
... ... / 111
- 111 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Rotten to the Core
Corporate "Dishonesty 'Officially'
Promoted !."
Cont
...
But of course we are not talking about a couple of rotten apples here.
As
Easterbrook and Fischel so clearly show, the corporate world is now governed by
an ideology
that
is rotten to the core.
After all, as the great
violate the law when it is profitable to
do so.
Now, the stink has risen. And slowly, but
surely, and hardly noticed, a counter-Chicago movement in
corporate law is bubbling up from law
schools around the country.
At
were created by the state to achieve
specified public goals. The corporation was created to build a canal,
for example. And then it was to go out of
business.
If the corporation decided to sell hot
dogs instead, it was acting beyond its powers, and a shareholder or
the attorney general could file an
injunction under the "ultra vires" (beyond its powers) doctrine –
forcing the company to drop the dogs.
Then, the states started to compete with
each other for more corporate business -- the infamous race to the
bottom. As a part of that race, states
stopped imposing strict limitations on corporate powers.
The corporate lawyers set up
no corporate activity was beyond a
company's defined activity. Ultra vires was dead, was the common view.
State incorporation statutes and articles
of incorporation almost invariably charter corporations only
for "lawful" purposes.
He wants attorneys general and trial
lawyers to look carefully at the possibility of bringing ultra vires lawsuits
against officers and directors of
corporate criminals.
At
over the nature of the corporation are
differences of political opinion.
o, those who see the corporation as a
creation of the state do so because we want to see strong public control.
Those who see in a corporation nexus of
private contracts (the
they want to defeat public
regulation. (The charter of
incorporation is like a birth certificate, and nothing
more, they argue.)
This new breed of corporate law reformers,
represented by the likes of
Mitchell of George
corporation back to the public woodshed.
But it is good to note that, after years
of bowing in subservience to the giant corporatists of the
a handful of law professors are beginning
to agitate against the regressive theories of their
colleagues.
Continued
... ... / 112
- 112 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Rotten to the Core
Corporate "Dishonesty 'Officially'
Promoted !."
Cont.
Their task is simultaneously difficult and
easy. Difficult, because the
in winning the academic -- and eventually
legal -- debate about what corporations are and how they should
be governed. Easy, because the
debate -- or at least significantly shift
the pendulum in the field -- by convincingly arguing simply that
corporations should follow the law.
Russell Mokhiber is editor of the
Washington, D.C.-based Corporate Crime Reporter. Robert Weissman
is editor of the Washington, D.C.-based
Multinational Monitor, http://www.essential.org/monitor
.
They are co-authors of Corporate
Predators: The Hunt for MegaProfits and the Attack on Democracy
(Monroe, Maine: Common Courage Press,
1999; http://www.corporatepredators.org
) .
(c)
Russell Mokhiber and Robert Weissman
This article is posted at: http://lists.essential.org/pipermail/corp-focus/2002/000105.html
............................................................
You have to have an extremely scheming,
brutal, vicous, cruel and un-loving mind to even think in those terms.
............................................................
* *
*
More Reasons
“Why” You Don’t
Hear About The Many Dangers Of (aspartame) Soy.
General theme from ... http://www.mercola.com/article/aspartame/hidden_dangers.htm.
1.) The
lack of knowledge and awareness of the problem by the general population.
From pressure from the Soy Industry and
Monsanto, the many scientifically documented harmful side-effects are not reported in the news media, newspapers, TV, food
industry, by popular authors of health and diet books, etc., etc. What
does make the news is a lot of misinformation.
2.) Because of this lack of knowledge and
awareness of the many
health hazards and the symptoms these hazards produce, people
don’t associate their symptoms and illness with the short or long term negative
side-effects they experience while eating Soy.
How Soy came into our food supply is a lesson in ...
1. How
the soy industry and the United Soybean Board can manipulate government
agencies around the world, such as the FDA,
to turn a blind eye to the many serious health dangers of eating soy.
The industry has aggressively lobbied in
invested millions in medical research. They spent more than a million
dollars on establishing the FDA’s spurious cholesterol
lowering heart claim alone. Their campaign has been nothing less than
brilliant.
2. How
the industry targets key influences as... food manufacturers... chefs...
dietitians... editors... writers... Naturopaths... the FDA
... Health Food Industry... MD’s... Schools of Nutrition... TV, radio,
magazine advertisements... USA & Canadian Cancer Societies
3. How
to bribe organizations such as... University research scientists &
institutions... Health Food Industry... soy industry scientists
4. How
to flood the scientific community with flawed and fraudulent
industry-sponsored studies funded by the soy industry.
... / 113
- 113 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
☺ i ☺
The Precautionary
Principle
“Error on the
side of caution”
Website links below
“Education
is the most powerful weapon you can use to change the world,” by Nelson
Mandela.
Google
Search http://www.google.com/search?hl=en&q=precautionary+principle&spell=1
http://www.partnersforchildren.org/Pages/gp.html
... Partnership for Children’s Health
and the Environment
http://www.mindfully.org/Precaution/precaution.htm
... Mindfully , Great list of Links
http://www.biotech-info.net/rachels_586.html
... AG BioTech - Rachel’s Weekly #586
http://www.monitor.net/rachel/r586.html
... Rachel’s Environment, Health Weekly
# 586,
by Peter Montague, National Writers
The Principle of Precautionary Action has 4 Parts ...
1.) People have a duty to take anticipatory
action to prevent harm. (As one participant at the Wingspread meeting
summarized the essence of the precautionary principle, “If you have a
reasonable suspicion that something bad might be going to happen, you
have an obligation to try to stop it.”). Einstein said, “...the world is a dangerous place to live in, not because of the people who
are evil, but because of the people who don’t do anything about it...”.
2.) The
burden of proof of harmlessness of a new technology, process, activity, or
chemical lies with the proponents, not with the general public.
3.) Before
using a new technology, process, or chemical, or starting a new activity,
people have an obligation to examine “a full range of alternatives” including ... the alternative of doing nothing, (in order to protect the well-being of
everyone.).
4.) Decisions
applying the precautionary principle must be “open, informed, and democratic” and
“must include affected parties.”
“The Precautionary Principle” is not really new. The essence of the principle is captured in
common-sense aphorisms, such as “An ounce of prevention is worth a pound of
cure” ... “Better safe than sorry” ... “Look before you leap” ... “Error
on the side of caution” ... etc., etc.
The US FDA’s “Poisonous Plant
Database” ... http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY ... lists Soy, and
(Flax and Linseed), and (Canola and Rapeseed) as “poisonous plants,”
and the FDA recommends that if you are injured by them, to contact your
local “Poison Control Center” in your area, (at ... http://www.aapcc.org/.),
or call 911.
“The Precautionary
Principle and Corporate Disclosure” ... http://gnp.enviroweb.org/precaution.htm
,
http://www.cpeo.org/lists/brownfields/2000/msg00079.html
,
http://www.millermicro.com/PrecPrin.html
, http://www.mphaweb.org/init_princ.html
.
Feb.
20, 1998, by
An attorney who provides strategic
counseling on corporate accountability to environmental, community, labor
organizations
Scientific
Uncertainty ... vs ... “Smokescreen
Uncertainty” ... the corporate language
- A New Corporate Initiative(Legal) Against
Disclosure
- Cloud the issues, confuse in order to
create indecision and delay.
The Precautionary
Principle … http://en.wikipedia.org/wiki/Precautionary_principle … Wikipedia, the free
encyclopedia … if the consequences of
an action are unknown, but are judged to have some potential for major or
irreversible negative consequences, then it is better to avoid that action … … … Origins and Theory – Hippocrates – First do
no harm – beyond reasonable doubt – Criminal Law - uncertainty … Application – Civil and Criminal Law – beyond a
reasonable doubt – cost and benefit analysis … International
aggrements and declarations … Environment
and Health – Public Health -
Toxicity - Drugs - bio-safety – Risk - informed consent … Criticisms – GMO – Vaccinatins - Hippocratic Oath
. ... / 114
- 114 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
The Precautionary Principle ... Continued,
Precautionary
Principle ... http://www.ratical.org/co-globalize/MaeWanHo/PrecautionP.html
“Use and Abuse Of the Precautionary Principle”
(ACIEP)
Biotech. Working Group,
Precautionary
Principle … http://www.mindfully.org/Precaution/precaution.htm
... Mindfully
Great
list of Links
Precautionary
Principle ... http://www.bio-integrity.org/ ...
http://www.bio-integrity.org/health-risks/health-risks-ge-foods.htm WHY CONCERNS ABOUT HEALTH RISKS OF G.E. FOOD ARE SCIENTIFICALLY
JUSTIFIED
http://www.bio-integrity.org/Advisory.html How
ADVISORY ON
1.) How the Food, Drug and Cosmetic Act Mandates the Precautionary Principle
2.) How the Food and Drug Administration Is
Violating the Law and Misrepresenting the Facts
Coalition against
BAYER http://www.cbgnetwork.org/home/Campaigns/Charter/charter.html Charter
of Rights, Charter of Rights Against Industrial Hazards, Use
with The Precautionary Principle.
Definition
... The Precautionary Principle is
a policy principle that states "When an activity raises threats of harm to
human health or the environment, precautionary measures should be taken even if
some cause and effect relationships are not fully established
scientifically."
The
issues ... As you likely
know, rates of childhood illness for a range of chronic disorders have been
rising. Many of these disorders, including some childhood cancers, asthma,
learning disabilities and behavioral disorders, have been linked to
environmental factors. Research increasingly indicates that children are not
adequately protected from pollutants in air, water, food and household
products.
The
Precautionary Principle ...
An estimated 75,000 chemicals are used in commerce today and released into the
environment, eventually reaching our bodies through the food we eat, the water
we drink, and the air we breathe. Despite known exposures to these substances,
the US Environmental Protection Agency has estimated that less than 10% of the
industrial chemicals produced in the largest quantities (over one million
pounds per year) have a full complement of publicly available basic
toxicological screening data. Only 12 chemicals have had full testing for
impact on the developing nervous system (as of 1998).
Research in recent years has demonstrated that children & developing fetuses
are especially vulnerable to health damage from toxic chemicals. Children are
not little adults. Their organs & physiological processes are still
developing, and toxic chemicals can disrupt this development, causing long-term
irreversible damage. Even exposure of parents to some substances can result in
health problems for their children. Unfortunately, our laws and policies still
focus on limiting chemical risks for healthy adults to so-called “acceptable”
levels, rather than preventing harm to children.
The ABC’s of
Confusion As A Weapon, (The Arsenal of Confusion) by Brain Leibovitz, PhD, 1994
... http://www.laleva.cc/supplements/abc_confusion.html
... When confronted with conflicting information, many people simply give up
believing anything on the topic of discussion: “If the experts can't even
agree, why should I bother to listen to any of them ?.”
... / 115
- 115 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
... Some Things
To Think About Below and On The Next 4 - Pages ...
The metabolism, physiology and
biochemistry of a ... fetus ... infant ... or child ... is fundamentally
different from that of an adult. A host of vital organ systems continue to grow
and mature from conception throughout childhood. At critical periods of developmental
change, these systems are susceptible to the toxic effects of pesticides and
toxic chemicals, both individually and "in mixtures." Many organ
systems, for example the nervous system and brain, can be permanently, and subtly damaged by exposures to toxic substances in-utero or
throughout early childhood that, at the same level, cause no measurable harm to
adults ( Jacobson 1996, CDC 1997, NRC 2000 ).
The endocrine (hormone) system , and
immune system, is perhaps even more sensitive
to toxic exposure than the nervous system, over the past decade, enormous effort has been put into the study
of how pesticides and toxic chemicals interfere
with normal endocrine signaling and function.
A significant body of research in animals
now shows that ..."ultra-low
doses"... toxic
chemicals on critical days of development can cause changes in hormone function and effects on organ development and function
that often only appear later in life. A growing number of these studies show
that low doses at a susceptible moment of development can cause more of an effect than high doses (vom Saal 1997, Alworth 2002, Hayes 2003. This is particularly relevant to childhood and fetal exposures via food & water where the
timing of the exposure is at least as important as dose. See the website, Environmental
Working Group, EWG at ...
http://www.ewg.org/issues/home/index.php
.
In the pregnant women, toxic ingredient in
soy cross the placenta, blood-brain barrier, “teratogenic,” causing birth
defects. The placenta does not represent
a barrier to these poisons. See
abstracts in this research paper for documentation. Pregnant women and their unborn child,
infants, and young children are at great risk to their health, both from short
and long exposure to soy ingredients in our food supply.
Remember, when the Titanic sank early Monday morning of
The 1998 meta-analysis report below points out
that “... there is no direct evidence for the beneficial effects of
phytoestrogens in humans ...”. Since
1998, there is still no direct
medical evidence proving the need for soy in our food supply, nothing has
changed and this is still exactly the case today as it has been for the last
several thousand years.
Toxicol
Lett. 1998 Dec 28;102-103:349-54.
1998 “Dietary
phytoestrogens and their role in hormonally dependent disease,” — Strauss L., Santti R., Saarinen N.,
Streng T., Joshi S., Makela S., Institute of Biomedicine
and Medicity Research Laboratory, University of Turku, Finland.
— “... there is no direct evidence for
the beneficial effects of phytoestrogens in humans. ... All information is
based on consumption of phytoestrogen-rich diets, and the causal relationship
and the mechanisms of phytoestrogen action in humans still remain to be
demonstrated ... In addition, the possible adverse effects of
phytoestrogens have not been evaluated ... It is plausible that phytoestrogens, as any exogenous hormonally active agent,
might also cause adverse effects in the endocrine
system, i.e. act as endocrine disrupters ...”.
Again,
in 2003, The United
Kingdom Chief Medical Officer, the highest medical officer in the UK has issued
a “Health Protection Advisory” about the long term reproductive harm to
children from soy protein. He has drawn
on the findings of at least four expert committees, going back to July
1996. In his Health Protection
Advisory,” he has warned all doctors that ...
... soy - based infant formulas
should be used only in exceptional circumstances, because of “... a risk to long term reproductive health
...”.
Further information on the UK Expert
Committee’s findings is in a March 2003 Report called, “Committee
on Toxicity of Chemicals in Food, Consumer Products and The Environment, Report
on Phtoestrogens and Health,”
and is at ... http://www.food.gov.uk/multimedia/pdfs/2003-03.pdf
, and it says by pointing out that ...
“... After reviewing the data
and conclusions in this report relating to soy-based infant formula, SACN
considered that there is cause for concern about the use of soy-based infant
formula. Additionally, there is neither substantive medical need for, nor
health benefit arising from, the use soy-based infant formulae ...”
... / 116
- 116 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
----- Original Message ----- -----
Original Message -----
From: Valerie
& Richard James , Soy Online
Service From: Leannji@aol.com
To: Gerald
Hernesmaa To: webmaster@soyonlineservice.co.nz
Sent:
Subject: Fw: God bless you for having this
page. Subject: God bless you for having this
page.
.
Hi
I'm
a 48 year old female who has been a vegetarian for 33 years. Of
course, this means I have consumed large amount s of soy products during
my life. When I was 39 years old, I went from being a slim,
athletic woman to gaining 10 -20lbs per year average. I dieted and exercised
and controlled this weight with difficulty, but I am still 40 pounds
overweight. I have also been extremely depressed. My doctor insists(and has over the last 7 years) that my
physical condition is all due to depression, but I disagree.
I think my depression is due to my physical condition.
Finally., last week, after 8 YEARS, I got
a different diagnosis--hypothyroidism. Then a week later, she tested further and
found that it was thyroiditis(hashi.)
After
reading your site, I am giving up soy forever. I had been taking quite a bit of
isoflavones after menopause(which coincided exactly with the onset of these
symptoms)., which didn't help at all, but I just kept taking them anyway,
not knowing what else to do.
I really don't want to ingest animals,
either for their thyroid hormones, or for protein from their flesh. This
is for religious reasons.
Do you have any suggestions for me?
Thank
you so very much. You don't know how much it means to me to have found your
page.
Leanne
******************************************************************
----- Original Message ----- -----
Original Message -----
From: Valerie
& Richard James , Soy Online
Service From: Valerie & Richard James ,
To: Gerald
Hernesmaa To: Toni Fairchild .
Sent:
Subject: Fw: Re: Thyroid . Sent:
Subject: Re: Thyroid
Hello
Toni.
We help the www.soyonlineservice.co.nz
webmaster with his mail. What a horrible tale you recount!
From the bottom up. >>>> No,
soy protein does not have GRAS determination. Soy protein was slipped into the food chain about 1959
even though the developmental research (funded by ADM and Mead Johnson)
demonstrated that it caused serios infertility problems in laboratory rats and
their offspring. This is
recorded in a series of papers in the Journal of Nutrition by Schultze, Liener
et al in the 1950's The only evaluation was in 1979 by the Life Sciences
section of FASEB, and soy protein failed
because of the risk of nitrosamines forming in the heat treatment. FASEB assumed the heat treatment was
removing the natural poisons & did not
evaluate their safety at all.
You
will find a fuller discussion of GRAS in the Home Page of www.soyonlineservice.co.nz
"Trouble for Soy Protein", including Dr Fitzpatrick's opposition to
the grant of health claim labelling by the FDA
The material in www.soyonlineservice.co.nz "Doses
Simplified" gives an
idea of how toxic the levels of isoflavones in the products your husband was
consuming were.
We cannot give medical advice. Your
husband's
Best
Wishes Valerie.
... / 117
- 117 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
----- Original Message -----
From: Toni Fairchild
To: divulge@xtra.co.nz
, Soy Online Service
Sent:
Subject: Thyroid
I
would like to know how to reverse the ravages of soy on ourselves?
My husband has hyperthyroid Grave's
disease since last Nov 02....and not been able to take the drugs to slow it
down. He did not take the radioactive iodine either, since his eyes were
already protruding. His health has diminished severely. I do feed him the
Weston A Price diet, low carbs, moderate protein and higher fat diet.....when
he eats more carbs, he is in big trouble. He lost about 15-20 pounds in the
beginning, but has gained it all back now....the last 3 months or so. We are
working with a naturopathic doctor here in
For me, I have low thyroid (Oct 03) and
starting taking 1 grain Armour per day plus Mon & Thur taking 2 grains.....this
helped with some increased energy but my body temp was still low, so my
naturopath got me some T-100 (dulse, thyroid,adrenal gland
l-tyrosine,bladderwrack, Irish moss, pituitary gland, spleen gland, thymus
gland, calcarea fluorica, lycopus virginicus) from Dynamic Nutritional
Associates, Inc. to get my body temperature up and this has been very
beneficial. I live here in FL and most months, not just the summer I got cold
to the bone every time I went into the grocery store & that was with a jacket....This
winter it's been great. I have been suffering with this for a lot of years, but
my thyroid #'s from my bloodwork have been in the normal ranges....now I know
what normal is....
My husband & I have sold Nutrilite
Products for over 25 years and we liked to use the products and promote them. I
used to make a protein shake at least 3-4 times a week (soy protein isolate
from Nutrilite), thinking I was fixing something great. Nutrilite has a well
recognized name, and I have always trusted them. In the last several years they
have been releasing new products....i.e.. protein bars, meal replacement bars,
weight management products, low carb stuff because of the craze the last few
years, well, I was never able to eat those bars but my husband was able
too....he always had an iron stomach, and thought he was doing himself a favor
by not stopping by a fast food restaurant, or buying a candy bar when away from
home. He used to eat at least 1 a day. Just about all these products have soy
in them. I've listed the ingredients on their newest bar.
Also, did 'soy' ever get the gov't GRAS
status, if so, when. I've asked this to one of the scientist there at Nutrilite
and have not got a reply back from them yet. I've been studying for quite some
time, some things fall into place and other things will eventually, I'm sure.
Thank
you so much for your insight!
Toni
Fairchild
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Great
taste, balanced nutrition Full
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replacement bars ... a good source of fiber -- at least
three times more than Myoplex® and one-and-one-half times more than
Slim-Fast ... Has 220 calories and only 2.5 grams of
saturated fat ... No artificial color, flavors, or
preservatives added
INGREDIENTS: Cocoa Crisp (Isolated Soy Protein, Tapioca Starch, Cocoa Powder, Calcium Carbonate),
Chocolate Coating (Sugar,
Palm Kernel and Partially Hydrogenated Palm Oils, Cocoa, Nonfat Milk, Sorbitan
Monostearate, Soya Lecithin, Vanilla),Corn Syrup,
Maltitol, Sodium Caseinate, Dried Cranberries (Sugar, Cranberries, Citric Acid,
Natural Flavors, Elderberry Juice Concentrate, Sunflower Oil), Arabic Gum, Palm
Kernel Oil, Natural Flavors, Glycerine, Dried Cherries (Cherries, Sugar,
Sunflower Oil), Inulin, Dried Figs, and 1% or Less of the following: Cocoa
Butter, Malic Acid, Carmel Color, Soy Lecithin. Sodium Ascorbate, Chromium
Yeast, Selenium Yeast, Copper Gluconate, Nicinamide, Molybdenum Yeast,
Ferrous Sumarate, Vitamin E Succinate,
Zinc Oxide, Vitamin A Palmitate, Manganese Gluconate, Calcium Pantothenate,
Vitamin K, Riboflavin, Pyridoxine Hydrochloride, Vitamin D3, Thiamine
Mononitrate, Folic Acid, Potassium
Iodide, Cynocobalamin, Biotin . ... / 118
- 118 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Just imagine, in order to accomplish “the
suppression of the truth about soy’s very serious multiple health hazards,” — [which, by the way, has also been very
efficiently, effectively and profitably inflecting untold, incalculable, “unimaginable” and needless pain, suffering, agony and torture onto tens of
millions of innocent people around the world every year] — there obviously has to be almost complete
and total cooperation by all or almost all of the “Participants,” (which includes but is not limited to
the soy industry, Monsanto, Dupont, Dow, regular food industry and health food industry, Naturopaths,
AMA, news media of various forms, chemical-pharmaceutical industry, many
academic institutions, most of the popular and famous authors of books
on nutrition, the American and Canadian Cancer Societies, the USA’s Department
of Agriculture, the US FDA, Health Canada, and many other governments and
government departments from around the world etc., etc., etc.) — have all
played their small part or large part, which ever the case may be, in
suppressing this valuable information with their “Prior Knowledge” of soy’s many serious health hazards for
years, by not giving to the public any “General Health Protection
Advisory,” or “Public
Health Warning” about
all these “Hidden Dangers” by those who know, “The Participants,” even after the soy industry
released it own research in May of 2002 adding further proof to what was already known in the general
scientific world, “... that soy damages the immune system
...”. This suppression of the truth is largely, if
not totally, because of the soy industries lobbying practices to governments
around the world and to their fellow “Participants,” and from various forms of news media
intimidation, very much like what has happened in the case of BGH. (See bottom of page 98.) In legal terms, this is a type of world wide
cover-up, a “Conspiracy Of Silence,” which has also become a very, very
extremely financially $$ profitable cover-up, for those involved. The “Participants” have to have an
extremely scheming, brutal, vicious, cruel and un-loving mind to even think in
those terms.
The more that scientists learn about the
many serious health hazards of soy
through their research, which occurs almost monthly, the more questions
are raised, including the all important question ... “Why
aren’t we, the public, being told about these KNOWN toxic, poisonous and
sometimes deadly cancer causing side-effects of soy so that we can try to
protects the ones we love ??.” The soy industries flawed
research and their arguments
that allow these serious health hazards to be ignored, through denials, are
purposefully and intentionally generated and used “to cloud the issues and
the truth,” and to “confuse
in order to create doubt, indecision and delay” through misinformation.
The FDA is increasingly mired in these complex and arcane scientific
arguments used by the
“Participants” to
support the soy industry’s flawed research according to scientists &
WHO/Codex Food Safety Standards for Soy Protein Products (page 6) ... bad science--(Shiv Chopra Health Canada
scientists & whistle-blower between 2000-2004) ... which keeps the general public ignorant
of the many dangers soy poses to our health from being in our food supply. These arguments are mostly generated by the “Participants,” which serve primarily as “delaying
tactics” in order to
keep soy in the world’s food supply for as long as possible, in order to maximize
profits for shareholders and the industry, which is EXACTLY like what
happened and the way it happened for over 20 years with the estrogen problems
in Hormone Replacement Therapy, HRT, before the truth halted those trials in
June 2002.
What Y☺u Can Do
With no end in sight to this stalemate, the consumer is wise to try to get
governments everywhere to ban adding soy ingredients to our food supply, and to
get governments to pass enforceable food labeling laws and practices. But,
in the mean time,
the consumer is also wise to talk about this topic as much as
possible in order to inform people in their own community, to get their local food
stores to carry a wide selection of foods without added soy ingredients, in the same way it was done before the year 2000, to minimize exposures to soy and soy
ingredients whenever possible by carefully reading all food ingredient labels
on all the food they buy, and to also remember that restaurants and hospitals
do not list the ingredients in the foods they serve people, even to cancer
patients.
So for the soy industry and their “Participants” to try and bend the scientific evidence
to try to make it fit what the soy industry and the pharmaceutical-chemical
companies wants it to look like, that soy supposedly prevents cancer, is
doing the very exact same thing the pharmaceutical companies did for over 20
years before June 2002, when the studies on Hormone Replacement Therapy, HRT, were stopped because these studies were proving that HRT was
causing the very illness in women, including cancer, that the pharmaceutical
companies were claiming and saying that HRT prevented. All this is what we feel
can be called “Crimes Against Humanity and Crimes
Against Nature in the extreme.” Soy being used as a weapon
of mass destruction, devastation, and unimaginable pain, suffering, heart ache
and death !!.
The weed of crime bears bitter
fruit. Does the soy industry and all of its
supporters really think they’ll all get away with it ??. Do they really think I, we, wouldn’t know ??.
As
the Roman Gladiators would say before they died in the great Roman Colosseum, “…
Those who are about to die solute you–( The Soy Industry and all of its
supporters, including many & various government departments ) !! …”, (for your clever, imaginative and
ingenious ways you have denied and intentionally hidden the truth
about the many serious & sometimes deadly health hazards of eating soy
from us, and then deliberately lied and conned us into believing
all those lies about the safety of soy…for well over 50 years).
... / 119
- 119 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Class Action Law
Suit Likely
Newest Research On Why You Should Avoid Soy
Cinderella’s Dark Side
By Sally Sallon and Mary G. Enig, Ph.D.
http://www.mercola.com/article/soy/avoid_soy.htm
From near the end of this research paper Part 3
From near the end of
the Newest Research On Why You Should Avoid Soy ...
Soy - The Next Asbestos ?.
"Against the backdrop of widespread praise...there is growing
suspicion that soy - despite its undisputed benefits - may pose some health
hazards," writes Marian Burros, a leading food writer for the New York
Times. More than any other writer, Ms
Burros's endorsement of a low-fat, largely vegetarian diet has herded Americans
into supermarket aisles featuring soy foods.
Yet her
Because the industry
is extremely exposed...contingency lawyers will soon discover that the number
of “potential plaintiffs” can be counted in the millions and the pockets
are very, very deep. Juries will hear
something like the following: "The industry has known for years that soy contains many
toxins.”
“At first they told the
public that 1.) the toxins were
removed by processing. When it became
apparent that processing could not get rid of them, 2.) they claimed that these substances were
beneficial. Your government
granted a health claim to a substance that is poisonous, and the industry lied
to the public to sell more soy."
The
"industry" includes ... merchants ... manufacturers ... scientists ... publicists ... bureaucrats ... former bond financiers ... food writers ... vitamin companies ... and retail stores. Farmers will probably escape
because they were duped like the rest of us. But they need to find something else to grow
before the Soy bubble bursts and the
market collapses: grass-fed livestock ... designer vegetables ... or hemp to
make paper for thousands and thousands of legal briefs (that are sure to come
and will soon follow) ... ( Expect no mercy ).
The above is also extracted from Nexus
Magazine, Volume 7, Number 3 (April-May 2000)
The US FDA’s “Poisonous Plant Database” … http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY … lists Soy, and
(Flax and Linseed), and (Canola and
Rapeseed) as “poisonous plants,” …
… and the FDA recommends that if you are injured by them, to contact
the local “Poison Control Center” in your area, ( at … http://www.aapcc.org/.
), or call 911. There are over 685 scientific research
abstracts listed, out of over 1,000 known, going way back to 1850, proving serious harm to human
& animal health. ( out of about 500 or more abstracts do exist for soy
alone since 1907 ). The Soy industry, food, health food
industries, governments and the “News and Advertising Media” have all been
lying to us. See pages 5, 6, 7, 113,
119, 121 … abstracts on pages 29 –
96.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
... / 120
- 120 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
-----
Original Message -----
From: "SOY ALERT: SOY ONLINE
SERVICE AND WESTON A. PRICE FOUNDATION"
<soy-adult-correspondence_reply@mailhost.groundspring.org>
To: <healthwise933@shaw.ca>
,
Sent:
Subject: SOY ALERT: POSSIBLE LEGAL ACTION ON
MEDICAL PROBLEMS CAUSED BY SOY
>
>
> SOY ALERT
> WESTON A. PRICE FOUNDATION
>
>
> POSSIBLE LEGAL
ACTION ON MEDICAL
PROBLEMS CAUSED BY SOY
>
> This letter is in response to your
e-mail to either Soy Online Service
(www.soyonlineservice.co.nz) or
the Weston A. Price Foundation
> (www.westonaprice.org)
with regards to your belief that you or your child may have suffered serious
physical or medical consequences
> as a result of ingesting one or more
products containing soy.
>
> A growing body of credible
medical and dietary research suggests that soy products may cause adverse medical and developmental
> conditions in susceptible persons,
especially children – who in some instances may be affected by soy products
consumed either by
> themselves (for instance, in baby
formula) or by their mothers prior to giving birth.
>
> The Weston A. Price
Foundation in cooperation with Soy
Online Service is exploring the causal connection
between soy and
>
various serious conditions – see attached listing. We
have also sought out competent attorneys in the
>
elsewhere,
>
who may develop medical evidence in a number of these cases to pursue damages
or other appropriate remedies against the
>
manufacturers and sellers of soy products.
>
> If
you would like to participate in these efforts, we urge you to contact the
Weston A. Price Foundation at ...
> westonaprice_soy@verizon.net. Upon receipt of your e-mail, we will
forward you, via e-mail with attachments, a questionnaire and
> release form. We urge you to complete
the questionnaire, fully and honestly, to the best of your ability. Also,
please sign and return the
> medical authorization(s) along with
the questionnaire, in order that we might gather relevant medical records in
those cases which
> warrant further investigation.
Mailing address and fax number will be provided to you with the questionnaire.
>
> PLEASE BE ADVISED, not all of these
potential claims can or will be pursued, even if we conclude that you or your
child may have
> suffered some adverse effects from
the consumption of soy products. It may be too late under applicable state laws
to pursue some
> claims; and in other cases, the
parties responsible for your condition may not be adequately identified, or the
recoverable damages may
> not warrant pursuit of the
responsible parties.
>
> However, if you would like us to
conduct a preliminary investigation of the circumstances of your potential
claim, without cost or
> obligation to you, then promptly
complete, sign and return the enclosed documents. We hope to be able to assist
you in this matter, if
> our inquiry develops evidence of corporate
responsibility for your medical problems or those of your child.
> .
> Sincerely,
>
> Sally
A. Fallon, President
> Weston
A. Price Foundation
> PMB 106-380,
>
>
(202) 333-HEAL
>
westonaprice_soy@verizon.net
>
> ... Continued ...
... / 121
- 121 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
March
29, 2004
SOY ALERT
WESTON A. PRICE
FOUNDATION , contact ... westonaprice_soy@verizon.net
.
POSSIBLE -“LEGAL ACTION”- ON MEDICAL PROBLEMS CAUSED BY SOY
continued
See
page 18 ... Soy is also called
by 8 - “Aliases-(false names)” ... “Vegetable oil -or- Shortening”
... “Textured vegetable protein”
“bouillon” … “MSG” ... “natural
flavoring” ... “Hydrolyzed protein -or- vegetable protein.” Also,
look for “Soy Oil” and “Soy Flour.”
>
> PARTIAL LIST
OF PRODUCTS CONTAINING
SOY ... (MSG is made from soy, http://www.truthinlabeling.org/index.html)
> Remember To Read “The Ingredient Labels” On All Of
The Foods You Buy !! ... and just change brands if necessary.
>
> Candy of all
types, Junk foods, and soft
drinks-( added soy oil) Canned
Tuna, Canned dry Soups Regular
Hamburgers, hot dogs, meat loaf
> Dairy
Products ... cheese, whip cream, yoghurt, margarine Pet Foods French fries cooked in (made
with) soy oil
> Diet Foods and Low Fat foods ... including
cookies, pastry, pies Prescription and other Medications Restaurant
Foods of all kinds and types
> Hospital Foods of all kinds, served to patients and staff Smoothies and
some Fruit Drinks Regular
pre-packaged meats, etc
> Meal
Replacement Beverages, and
Diet beverages Soy
Isoflavone Supplements Salad
Dressings, Mayonnaise (in Soy oil)
> Protein Drinks served to cancer patients in Hospitals Soy Infant Formulas Soy Milk, and Soy Sausages
> Snack-Energy
Bars containing soy products-(ingredients) In women’s Skin Care product Soy
Ice Cream, and regular Ice
Cream
> Soy-based
Bread, pastry, and
regulars with various soy ingred.’s Tofu – Tofu – Tofu Veggie anything – meat
substitutes, salads
> Vitamins … Vitamin E - (put in soy oil) … various types of
Supplements
>
> MEDICAL CONDITIONS
POSSIBLY ATTRIBUTABLE TO – MAYBE
BROUGHT ON BY
– SOY CONSUMPTION
> A growing body of credible
Medical and Dietary Research suggests that EATING SOY products is also
one of the CAUSES of developing these Medical Conditions
> The US FDA’s “Poisonous Plant Database” at ... http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY ... lists Soy as a “poisonous plant,”
> The genistein in
soy is a Topoisomerase II-poison.
> Asthma
> Brain and
Nervous System damage ...
> Genistein in soy destroys the “myelin sheath” surrounding and protecting the
nerves, spinal cord, and brain cell tissue, as in Alzheimer’s -
> Parkinson's Disease, M.S., and also,
learning disabilities as in ADD / ADHD.
> Chronic
Fatigue
> ( Cancer, Breast,
other ) ... added by Gerald Hernesmaa, (who’s wife Deanna (Deonaa) died a
slow painful death on
> liver cancer while - from -
because of eating soy in her food), based on a growing body of
scientifically credible medical & dietary research.
> Depression
> Diabetes
> ( DNA and
Chromosome Damage, *Immune System Suppression ) ... added by
Gerald Hernesmaa ... based on a growing body of scientifically credihle
> medical and dietary research ... see
pages 7, *10 soy weakens immune system, 13, 17, 34, 40, 52, 53, 55, 58,
61-65, 73, 80, 90.
> Heart
Arrhythmia, ( For the above quoted pages on this and
these other illness ... refers to this -
144 page - Soy Research Paper. )
> Heart or
Liver Disease
> ( Hypospadia ... http://www.amershamhealth.com/medcyclopaedia/Volume%20IV%202/HYPOSPADIA.asp
) ... added by Gerald
> Infertility
/ Reproductive Problems
> Irritable
Bowel Syndrome
> Osteoporosis ... added by
Gerald ... based on a growing body of
scientifically credible medical and dietary research
> Pancreatic
Disorders
> Premature or
Delayed Puberty , ( Pseudo Puberty ... http://www.emedicine.com/ped/topic1881.htm#
)
> Rheumatoid
Arthritis
> Thyroid Conditions:
> - Auto-Immune Thyroid Disorders (
> - Hypo and Hyper thyroidism ... Thyroid Cancer ... Goiter ...
other thyroid disorders ... Thyroid Nodules
> Uterine Cancer
> Weight Gain - obesity — from
thyroid problems ... Weight Loss - anorexia — from pancreas problems, soy
contains potent enzymes inhibitors that
> block the action of trypsin and
another enzymes need for protein digestion.
>
> SYMPTOMS
OF POSSIBLE DISORDERS
ATTRIBUTED TO SOY
>
> Always
feeling cold or warm Brittle
nails Hyperactivity The Reoccurrence of cancer
> Anemia Eczema Learning
deficiencies Sore
bones and joints
> Behavioral
problems Hair
thinning or loss Lethargy or
low blood pressure Watery or
swelling eyes
... / 122
- 122 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
(( healthwise933@shaw.ca ))
Gerald and Deanna - ( Deonaa )
.
Soy Was The Major Contributing Cause In My Wife Deanna-(Deonaa) Death From Cancer
The weed of
crime bears bitter fruit. Does the Soy Industry and all of its supporters
really think they’ll all get away with it ??.
With all
the publicly available scientific proof since 1907, do they really think that we wouldn’t know ??.
How would
you feel if you were forced to feed poison to the one you love as they slowly
die
because of
it, in your arms ??. Soy also caused the reoccurrence of Deanna’s
cancer 3
times in less than 2 years. Soy Online Service website
helped to
save my wife’s life, twice in 1 year. The
* Sir Jason
Winters Herbs may have saved
her life ??,
if soy had not poisoned
her first. See *Note first.
;
*Note … Be very, very careful. Soy
is in many Sir Jason Winters products.
Be sure to check the ingredient labels for
each one.
Eating Soy poisoned my wife, Deanna (Deonaa), and
also caused her cancer cells to grow, and was the major contributing cause in her death from breast, bone
and latter liver cancer on Dec 15, 2002. The soy industry and all of its supporters,
(referred to as the “Participants” on page 118), stole from us our
happiness and our future together. I
can prove it, and I
have the tumor marker blood tests, CEA and CA 15.3, to prove it. It
was a very slow, painful death that could have been easily avoided, if they,
the our Doctor and the dietitian for the patients at
.
We
were married for 36 and 1/2 years, and we dated for 4 and 1/2 years in
high school before we got married. Deonaa - (Deonaa) discovered a breast lump in the summer of 1996. She was afraid and didn’t tell me about it until the end
of Jan. 1997. She went to the Medical Doctor for it in Feb.
1997, had
mammogram, blood tests, biopsy, and ultrasound for the breast lump. She did not
want to have an operation of any type, no chemotherapy or radiation, and no more x-rays. From what she was told, these tests could not
tell if her breast lump was cancerous.
This is when she insisted that we starting eating soy, soy milk, soy
burgers, etc.
.
She
tried to do the holistic approach from what she could find out and read
about. Everything she found to read
convened her to eat soy, and insisted that I eat soy as well. She read a lot of books on the topic of cancer
and breast cancer, and she said that there was a lot of contradictory
information on the topic. She had to
sort things out, decide what to do, the best she could. She had no real guidance on the best holistic. She knew that the mainstream medical system
had no real answers. Her approach before
the operation didn’t do any good because she didn’t have any good guidance from
anyone with holistic experience. Her
approach was hit and miss, fly by the seat of your pants, so to speak. It wasn’t until a couple of weeks after her
back operation, May 1999, that she found real guidance in the holistic approach to cancer
from “The Centre For Integrated Healing” in Vancouver, BC, Canada. Dr. R. Rogers was her Doctor there.
But the Centre also recommended soy for their cancer patients in their “Healthful
Fruits and Vegetables”
list of recommend foods to eat. From the Centre, she used 714x, Hydrazine
Sulfate, and eventually Escador. We finally thought she was on the right track.
Over the next year, she recovered from the operation about 98%. She was also taking “Tamoxifen”
from the BC Cancer Agency.
But no
one, not anyone, had ever told us that the scientific research has proven for 40 years that soy causes cancer
and causes existing cancer cells to grow ... or
… that genistein in soy is a Topoisomerase II-poison, (well known since 1989 see
pages 32, 34, 40, 42, 44, 70-73, 81) … or … soy interferes with, negates or overwhelmes the inhibitor effect of tamoxifen on MCF-7 tumor
growth !!,
see page 47-(2001), page 52-(2002).
.
We joined Neways in May 2000, & Deanna was taking Neways “Maximol
Solution” with Soy Lecithin in it from about July-Aug 2000, and stopped May 2001. We never thought
to read the label until May 2001, 4 months after we found out about the dangers of soy. But in Dec 2000 - Jan 2001 Deanna had her first reoccurrence of bone
cancer. We didn’t know why. She had been doing so good for a year and a
half. She got discouraged. She had 5 treatments of radiation for her
bone cancer, no chemo. Then one week
after the radiation treatments, in mid Jan. 2001, she was given a article called ... “The
Newest Research On Why You Should Avoid Soy,” an article on Dr. Mercola’s website at
...http://www.mercola.com/article/soy/avoid_soy.htm
. A light went on after reading this,
and she knew why he had her reoccurrence of cancer, and why her breast
lump had turned cancerous. But she still
didn’t know that Maximol Solutions had soy in it. The article points out that soy causes
cancer, causes existing cancer cells to grow and can turn non-cancerous tumors
cancerous. The same day she read the
article, we threw out all food with soy listed on the ingredient labels, except
Maximol Solutions. Her
tumor marker blood test, CEA and CA 15.5, that measure cancer activity
in the body, started
going down after May 2001. By Sept. 2001, her blood test were about 50% of what
they were 4 months after she stopped eating soy and soy products. All this time, Since the summer of 2000, we trusted Neways. We told our sponsors about the problems with
soy in Jan 2001. They didn’t tell us that
their product had soy in it. We also
didn’t think to read the label of the Maximol Solutions until May
2001. Then, right away we contacted Neways, we
returned the product and they gave us a refund.
Other than that, at
home we did a very good job of avoiding soy in our food by reading all the food
ingredient labels of the foods we bought, restaurant foods were a no-no as they
do not list the ingredients of their foods.
...
/ 123
- 123 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Soy Was The Major
Contributing Cause In My Wife,
Deanna-(Deonaa), Death From Cancer
The weed of crime bears bitter fruit. Does the Soy industry
and their supporters really think they’ll all get
away with it ??. Do they really think
we wouldn’t know ??.
;
.
Then, on Tuesday evening Oct. 23, 2001, we went to the Planetarium in
.
This time she got real discouraged. She didn’t want to take anything. Then she found out about Bio-cell Therapy at Ubiquity Wellness Centre, Vancouver. BC. She took that and was
feeling and getting better until she mistakenly followed the Lemon Cleans Master Cleans Lemon Diet.
That gave her severe dehydration and put her in the hospital in Aug. 2002.
We found out about Sir Jason Winters Herbs about the same time and she took them
right away and over 3 week period and started feeling better, and continued
taking them. She came home mid Sept. 2002 feeling and getting better. Then the home care nurse made a mistake on
the medications and Deanna ended up in the hospital again, mid Oct 13, 2002.
There she started to recover again while still taking the Jason
Winters herbs. But after a month into
the 2 months she was in the hospital we found out that 90 % of the hospital
food has soy in it from the dietitians computer data base print out.
.
When she went into the hospital last fall,
Oct 13 - Dec 15, 2002, she was there
for over 2 months before she died. At the beginning of the last month in
hospital, I, we found out that, according to the hospitals dietitians computer
data base, & that print out, 90% of hospital food has soy added to it from
the wholesalers, the bulk manufactures. I told the doctor and the dietitian
about the dangers of soy and gave them information on it, even photocopy of
research abstract proving it, & asked them if the hospital would bring in
food that did not have soy in it for Deanna. But all they said was that soy was
controversial & wouldn’t believe me or take me seriously. They would
not bring in extra food for her without soy in it, even after I gave
the dietitian and our Doctor a photo-copy of this abstract from PubMed. See pages 47, 52.
i i i , i i i , i i i , i i i - Soy Stimulates
breast cancer growth. Yes
!!.
2001 “Effects of soy
phytoestrogens genistein and daidzein on breast cancer growth,” – de Lemos M.L., Ann
Pharmacother 2001 Sep;35(9):1118-21., B. C. Cancer Agency,
— Objective: to determine whether genistein and daidzein, the major phytoestrogens in soy, can
stimulate breast cancer growth ??.
; i ; —
Women with current or past breast cancer
should be aware of the risks of potential tumor
growth when taking soy
products.”
— Conclusions: Genistein & daidzein may stimulate existing breast tumor growth and antagonize effects of tamoxifen
Eating poison interferes with everything. A week before Deanna died, she said to me
that she did not want to die, by that time, her throat had gotten smaller. She
couldn’t take the Jason Winters Herbs unless they were broken up into small
pieces, and by then she was getting discouraged and didn’t want to take them as
often as she needed to. On Sunday
afternoon, Dec 15, 2002, after
taking morphine for 2 days she died in a coma. During the last 2 days, from hand signals,
squeezing, Deanna could tell me that she was in a lot of pain, and if she
wanted more morphine. The nurses
wouldn’t believe me, and I had a difficult time getting the nurses to give my
wife enough morphine to stop the pain.
On Sunday morning, I told our Doctor what I was experiencing and our
Doctor said that what I was experiencing was not unusual, it happens. The Doctor instructed the nurses to give
Deanna more morphine, and few hours before Deanna died, and they did.
.
Eating
Soy was the major contributing cause in my wife’s death from
Cancer. I can prove it, and I also have the tumor marker blood tests, CEA and CA 15.3 to prove it. It was a very slow, painful death that could
have been easily avoided, if they would have listened to me, when she was in
the hospital. We feel that Soy was also
the single greatest cause of her getting cancer & also the single greatest
cause of the 1st, 2nd and 3rd reoccurrence of
bone cancer, and her eventual liver cancer shortly before she died. The weed of crime bears bitter fruit. Does
the soy industry really think they will get away with it ??; do they really
think that we wouldn’t know ??.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
...
/ 124
- 124 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Patient Food
Items
Not
always available at every meal or every day
Foods
That Do Contain Soy Ingredients Foods That Do Not
Contain Soy Ingredient
(as far as she, the dietitian, nutritionist can tell.)
Meats and Alternatives Meats and Alternatives
Breaded Perch-(soybean oil, soy flower) Breaded Fish-(soy oil) Poached
Eggs Canned Salmon Cod sliced
Breaded - Pork Cutlet Salisbury
steak-(textured soy protein) Canned
Tuna-(mixed with other ingredients in sandwiches ??.)
Ground Beef-(soy flower, as in meat loaf, meat balls, hamburgers) Chicken Fried / baked-(cooked in
what oil ??, Soy ??.)
Veggie Burgers * Chicken
Fried / baked-(in what oil, soy ??, yes) Ham
for sandwiches Pork Sausage
Ham Roast
Red
Kidney Beans Garbanzo Beans Bacon
Starches Starches
Whole Wheat Bread-(may contain soy)
60% Whole Wheat Bread -(may contain) All cereals
on the menu - (hot and cold)
Pancake Mix *
Mashed Potatoes-(from a flake/ mix) All
Pasta - (Plain) Bread sticks
Melba Toast
French Fries-(and / or soy bean oil.) Stoned Wheat Thins Premium Plus Saltines - (Christie)
Social Tea Cookies Digestive
Cookies Arrowroot
Cookies Graham Wafers Pie
Shells
Cereals,
all bran, bran flakes, special k, Cream of wheat, Oatmeal
Puffed
rice, rice krispies, raw bran
Soups
- Cream of Celery - (soy protein
isolate) Low sodium Beef Broth
Low sodium Chicken Broth
- Cream of Chicken and Cream of Mushroom Hospital made soups
??.
Hospital made soups ??. Beef
Broth Chicken Broth
Dressings / Condiments
Italian
Dressing-(calorie reduced) Miracle Whip
Dressings Gravy Butter Bicel
Margarine
French 1000
Soy Sauce BBQ
Sauce-(HVP) Worcestershire Sauce Strawberry and
Raspberry Jams Fruit Spread
Hollandaise Sauce Kraft
Light style orange spread and grape spread
Apple
/ Grape Jelly Orange Marmalade Salt / pepper
Desserts Desserts / Fruit
Jell-O Pudding Cups *
Pre-made puddings ??. All
fresh & canned fruits All Juice Jell-O
Whipped Topping Muffins ??. Peanut
Butter sherbert and Ice Cream-(modified milk ingredients)
Cakes - (margarine or shortening is used) * Pudding-(made in our kitchen) Lemon and Tapioca pudding
.................................................................................................. Sweet
Tart shells Yogurt plain and fruit-(mod. milk ingred.)
* * *
No Soy
Ingredients
... Continued ...
Dairy Vegetables
Process Cheese Slices Cottage
Cheese Cheddar Cheese All
vegetables Cream Style Corn Tossed Salad mix
Brick Cheese Cream
Cheese Parmesan Cheese
Grated Cheese - (used to top casseroles, has modified milk
ingredients) ... / 125
- 125 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
----- Original Message -----
From: Valerie
& Richard James , Soy Online
Service
To: ERIC
JOHNSEN
Cc: Mike
Fitzpatrick , Gerald Hernesmaa
Sent:
Subject: Re: Soy question from
Hello
Eric .
We help the webmaster at www.soyonlineservice.co.nz with
his mail. You should ask that question of the National Cancer Institute, and
ask them where they get their funds.
If you go to www.soyonlineservice.co.nz "Phytoestrogens
- Cancer," you will
see the webmaster's comments...and his opinion about the lowest form of life.
In
fact, scientists at the FDA have written for years that soy isoflavones are
carcinogens.(see next email). It was even so stated in "Chemical
Carcinogens", the
text book of the American Chemical Society, in 1976.
The trouble is that the bigwigs in control
at the FDA are directed by politicians who are in the pockets of the soy
companies. With that much money they can buy anything and everybody and spread
as much confusion as they wish.
Good Luck, Valerie.
..................................................................................................................................................
----- Original Message -----
From: ERIC
JOHNSEN
Sent:
Subject: Soy question from
I would like to know why the National Cancer Institute has posted information
saying that isoflavones from soy will prevent cancer cells from growing ?? ....
Why does all of this seem confusing?
Please comment.
Thank You
Eric
...
/ 126
- 126 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
.
----- Original Message -----
From:
"Valerie & Richard James" divulge@xtra.co.nz
Also see ... #184, 1916, FDA file #: F06318, (page 83 here)
To: talkingpoint@bbc.co.uk
1907
Sent:
Subject: "IS THE AMERICAN EMPIRE
GREEDY". ABSTRACT OF RESEARCH BY
Hello
"Talking Point'.
Please consider the work of US FDA
scientists in the attachment. Also look at the FDA data base of "Poisonous
Plants" here. - http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY
, of which Kuan's work is # 96 on the list. (See abstract below)
We help the scientists at www.soyonlineservice.co.nz and it
is quite evident from the existing published research they present that soy
has been known to cause ... thyroid harm for 70 years ... to be estrogenic
and to cause infertility for 50 years ... to be Carcinogenic and Cytotoxic
for at least 40 years. (Cytotoxic
... toxic to cells, Any agent or process
that kills cells, as Chemotherapy, radiation, “Webster’s New World Medical
Dictionary,” click on ... http://www.medterms.com/script/main/art.asp?articlekey=19883.).
Yet there is a huge subsidised
international push by the US Dept of
Agriculture, USDA, to promote the export to the world of soy meal and
protein based on a huge political promotion of it as "healthy".
The US FDA Center for Food Safety and
Applied Nutrition in
So we at www.soyonlineservice.co.nz think
the
As one very knowledgeable environmentalist
said years ago to us..."if this were widely known it could alter the whole
basis of the European C.A.P., because if soy protein were safely processed it
could not be the cheap protein that undercuts all others”.
Sincerely,
Valerie for www.soyonlineservice.co.nz
* *
*
-
http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY
...
1991 “Determination
of phyoestrogens in soy-based infant formula,” — S.S. Kuan, O..J. Francis, A. S. Carman, P.P. Umrigar and G.M. Ware, Toxicon, 30, 5-6, 527 , 1991,
(U.S. FDA, Department of Health and Human Services, Research Center, USA), and
10 th World Congress Report.
— Infant formula containing
soy protein have been available commercially for more than 50 years. Such formulas are designed and manufactured
for infants who are allergic to cow milk.
Soybeans are known to contain estrogenically active compounds,
phytoestrogens. An earlier publication
from th is laboratory showed that there was a significant carry-over of soy
phyoestrogens into its processed products.
— Soy-based infant formulas
contain 2 – 2.5 % soy protein isolates.
For some infants the formula is the sole source of nutrition for growth.
— The carcinogenicity ... cytotoxicity ... estrogenicity ... of
phytoestrogens have been reported in a previous publication and elsewhere. Consequently, it is imperative that the
formula be free of toxicant or that it be physiologically safe for infant
consumption.
— To determine whether
phytoestrogens are a potential hazard to the infant, a rapid simple, reliable
and inexpensive method for the determination of phytoestrogens in infant
formulas is needed. Many analytical
methods have been developed for the determination of phytoestrogens in soybean
and its processed products, but none of these methods are suitable for use in
assaying the phytoestrogens in soy-based infant formulas.
— A high performance liquid
chromatography (HPLC) method developed in this laboratory for the determination
of phytoestrogens in soy-based infant formulas is described. The method involves the extraction of
phytoestrogens from the infant formula with acetonitrile / methanol / acid /
water and the separation of the separation of analytes of interest in the crude
extract by HPLC with u.v. detection.
... / 127
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
Ms
Shellee
Team
Leader; Nutrition Policy,
Division
of Dockets Management, By
E-MAIL and By AIR-MAIL
Food
and Drug Administration,
USA, fdadockets@oc.fda.gov
, Phone (301)
827 – 6860 .
(
Docket # 2004Q-0151 ) Solae Corporation
Health Claim, re: Cancer
.
( FDA Docket # 2004Q-0151 ) - Solae Corporation Requests
Health Claim, re: Qualified Health Claim: Soy Protein and Cancer
. http://www.fda.gov/ohrms/dockets/dockets/04q0151/04q0151.htm .
Dear
Ms Anderson,
In preparing this petition for filing we
would like your staff to consider the following information. These are all
abstract references to research published in the NIH Medline database, and the full research is available via
these abstracts. You can see that these are from some very reputable research
institutions, and some like the Dept of Energy and NCTR are Federally operated
and funded. Soy Information Service is shocked that a publicly held corporation
would seek health benefit claims-
labeling, without revealing very well-documented risks of cancer causation and acceleration by the same product.
These are risks to consumers of cancers
from the Solae (and other) soy products, and do not include the other
well-known risks to other organs and bodily functions posed by soy consumption.
For instance, FDA scientists Dr D M
Sheehan and Dr D Doerge have raised some of them in their letter to the FDA, here
at ... http://abcnews.go.com/onair/2020/2020_000609_soyfdaletter_feature.html
, and here at ...
http://www.mercola.com/2001/jun/30/soy_fda.htm
.
Concerns about the potential
carcinogenesis of modern soy is not
new. For example, …
(1.) the Committee for Food Safety was worried about it in 1966, … (2.)
the definitive textbook “Chemical Carcinogens”
published by the American Chemical Society in 1976
had a chapter titled “Plant Carcinogens” that identified
soy isoflavones as known carcinogens, … (3.) the Life Sciences
Committee of FASEB in its 1978 “Evaluation of Soy Products for Human
Consumption” for the Food and Drug Administration (SCOGS-101 under contract to
the FDA # 223-75-2004) declined GRAS determination because
of the risks of carcinogenic nitrosamines, lysinoalanines, and nitrite
occurring during the modern processing. (Not to mention the other scientifically
documented natural occurring carcinogenic chemicals in soy called genistein
and daidzein).
(4.)
Moreover in 1999, an application by Archer Daniels Midland Corp for GRAS
determination of GRAS (GRN 00001) for
isoflavones was declined due to the failure of the applicant to reveal health
risks.
This is exactly the present situation, and
Soy Information Service urges you to follow the same course now and to decline
to file this present application.
Yours
Sincerely,
Soy Information Service,
pp
Richard F James, Director, MBA LLB
... / 128
- 128 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Coke to Launch
Cholesterol-Reducing
http://story.news.yahoo.com/news?tmpl=story&u=/nm/20031024/hl_nm/food_coke_oj_dc_1
Fri. Oct 24,
Yahoo! News,
ATLANTA (Reuters)
- Soft drink maker Coca-Cola Co., which is battling rival PepsiCo Inc. for control the of growing health drinks market, said on Friday
it was preparing to launch a cholesterol-reducing orange juice.
The world's largest soft drink maker will
begin rolling out Minute Maid Premium “Heart Wise”
on Monday in the
The
product will contain “Plant sterols”,
an additive that has been used in cholesterol-fighting margarine and other food
products. “Plant
sterols” have been shown to cut bad cholesterol
levels by about 10 percent when used consistently.
More than 41 million Americans have high
cholesterol, a key risk factor for heart disease, according to the American
Heart Association at ... http://www.ama-assn.org/
, and (news
- web
sites) , See news at ...
and web
sites at ... http://search.yahoo.com/search?p=%22American+Heart+Association%22
. Another 60 million or so have
moderately elevated levels of the fatty substance.
"That is a pretty good customer
base," Coca-Cola spokesman Ray Crockett said. "People with moderately
high cholesterol will find this product will help them reduce their cholesterol
significantly."
Crockett said the company had conducted “a
clinical trial” to
back up the drink's health claims and had obtained approval from the Food
and Drug Administration, FDA, http://www.coreynahman.com/FDA_Page.html
See ... (news
- web
sites) , See news at ...
. http://search.news.yahoo.com/search/news/?p=%22Food%20and%20Drug%20Administration%22&c=&n=20&yn=c&c=news&cs=nw , and
the web sites at ... http://search.yahoo.com/search/dir?p=%22Food+and+Drug+Administration%22&h=c
, to market the drink. Results of the clinical
test will be available “next” month ??.
Atlanta-based Coca-Cola first revealed its
plans to launch Heart Wise in an interview with Beverage Digest.
John Sicher, the trade publication's editor, said the drink was on the cutting
edge of a new wave of innovative beverages.
"This is real innovation in that it
provides a true functional benefit," Sicher said. "It uses a beverage
as a delivery system for an ingredient that will really help people."
Consumers
would have to drink two 8-ounce servings of Heart Wise
per day to get the suggested daily amount of 2 grams of sterols needed to lower cholesterol, according to
Coca-Cola. Each serving contains about 110 calories.
The product will have to be kept refrigerated.
BUT ... Are They
Harmful ... ?? ... Do They Pose Any Health Risks ??
“Sterol estrogens” were found to be
of the highest order
of estrogenic activity, even more than Soy.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
... / 129
- 129 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
“Phytosterols”
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
The new breed of
wonder-chemicals ?.
and very, very toxic too !!.
; i ;
Phytosterols are
natural plant estrogens. Because of their
reputations in folk lore as abortifacients, menstrual cycle disruptors and
ecbolic (hastening labour or miscarriage) agents and are known to stimulate
uterine tissue and have hormonal influences on the reproductive tract, the
World Health Organization sponsored a huge study to investigate "Natures
Contraceptives". This can be accessed through the April and May 1975 issues of the
Journal of Pharmaceutical Sciences including
i i i , i i i , i i i , i i i
-
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=167146&dopt=Abstract
.
- http://www.soyonlineservice.co.nz/07abstract.htm
.
1975 “Potential
value of plants as sources of new antifertility agents I.,” – N.
R. Farnsworth, A. S. Bingell, G. A. Cordell, and others., J Pharm Sci. 1975 Apr; 64 (4) 535-598, 1975.
— PIP: A comprehensive review
of plants that possess contraceptive or interceptive, abortifacient, ecbolic,
oxytocic, or emmenagogue properties is presented. The plants reviewed are those
which have a folkloric reputation of contraceptive effects and those which have
been tested on laboratory animals for their antifertility effect. The preovulatory, preimplantation, and
postimplantation antifertility mechanisms of plant substances affecting the
hypothalamus-pituitary, ovary, oviduct, uterus, or vagina are discussed in
terms of reproductive differences among laboratory animal species. Lithospermic
acid, m-Xylohydroquinone, coronaridine, rutin, and rottlerin are among the few
active antifertility principles to be identified in higher plants. Volatile
oils, quinine and castor oil, and sparteine have been used as abortifacient
agents, but not with consistent success, and often with toxic, if not
fetal, side effects.
Publication
Types:
Review
PMID: 167146
[PubMed - indexed for MEDLINE]
Quotes
The world population explosion has pointed out the need for new and
effective contraceptive agents... ...it can be seen that 565 species of plants are known to have
a folkloric reputation for use as abortifacients, ecbolics, or
emmenagogues. Of this 565 species, 225
have been shown to elicit a stimulant response when tested against uterine
muscle either in vitro or in vivo.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
... / 130
- 130 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
The new breed of wonder-chemicals ?.
Continued
i i i , i i i , i i i , i i i
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1151641&dopt=Abstract
.
- http://www.soyonlineservice.co.nz/07abstract.htm . Scientific Abstracts
1975 “Potential
value of plants as sources of new antifertility agents II.,” – N. R. Farnsworth, A. S. Bingell, G. A.
Cordell, and others.,
J of Pharm Sci. 1975 May,64 (5) 717-754.
— PIP: Literature on the
phytochemical study of plant estrogens is reviewed. The coumestans reportedly
have a greater degree of estrogenic activity than the isoflavones. Diethylstilbestrol is the prototype of
the synthetic silbene derivatives. Of the natural stilbenes, only rhaponticin
possesses estrogenic activity, though this is not firmly established. 6,
4'-dihydroxyflavone has also been reported to have estrogenic activity.
— Coumestrol and genistein
have been shown to compete with 17beta-estradiol for binding sites in the
uterus of young rabbits. Vinblastine, demecolene, and podophyllotoxin posses
known cyto toxic, antifertility properties. Naturally occurring steroid estrogens, estrogenic isoflavins, coumestans, plants with reported
estrogenic activity, and cytotoxic agents with antifertility properties are
listed along with their plant sources.
PMID: 1151641 [PubMed - indexed for
MEDLINE]
Quotes
— A number of estrogenic
sterols have been reported as being derived from higher plants.
— If one inspects the
sturctures of the estrogenic sterols, isoflavones, and
coumestans, one can see a
striking similarity of the skeletal structures of these compounds with the
structure of the synthetic estrogen diethylstilbestrol.
— The order or degree of the
biological activity of each of the three main groups of natural estrogens has
been investigated.
— The sterol estrogens were found to be of the highest
order of activity followed by the coumestrols and then the isoflavones.
***
*** *** ***
***
; i ; The study concluded that ... “If one inspects the structures of the estrogenic sterols, one can
see a striking similarity of the skeletal structures of these compounds with
the structure of the synthetic estrogen, diethylstilbestrol”.
at ... http://www.soyonlineservice.co.nz/04soy&DES.htm
,
; i ; “... (Diethylstilbestrol is a synthetic estrogen that caused “cancerous” birth defects in the daughters of women who took it while pregnant. The defects did not
become apparent until those young women reached maturity. Subsequent events
showed that male reproductive function was also impaired.
--- “... DES is so potent and harmful that it is banned as a
residue of growth promoters in beef liver
at one
part - in - two billion ...”
The sterol
estrogens were found to be of the highest order of
estrogenic activity, followed by the coumestrols and then the isoflavones.
See graph illustration on SOS website page.
; i ;
... / 131
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
See graph illustration
on Soy Online Service website page. For instance, researchers at Duke University
Division of Reproductive Endocrinology and Infertility found
"Beta-sitosterol may compete with cholesterol and interfere with the
synthesis of gonadal steroid hormones...and may create a neonatal environment
with low endogenous levels of estrogens....The hormonal environment during the
critical period exerts permanent organisational effects that may affect the
behaviour in adult animals.
1995 “The effect of
neonatal exposure to diethylstilbestrol, coumestrol and B-sitosterol on
pituitary responsiveness and sexually dimorphic nucleus volume in the castrated
adult rat,” – B. Register, M. A. Bethel, N. Thompson, and others.,
Jr. Proc Soc Exp Biol Med 1995 Jan;208(1):72-7
— These data show that
exposure to environmental estrogens early in development alters both
postpubertal pituitary responses to GnRH and basal LH secretion in females...
— Full Abstract And Quotes
Here
— The above rodent study has
been confirmed by Canadian researchers.
1995 “The
phytoestrogen B-sitosterol alters the reproductive endocrine status of
goldfish,” – D. L. MacLatchy, D. J. Van Der Kraak,
Toxicology and Applied Pharmacology 1995;134, 305-312.
— These results suggest that
beta-sitosterol reduces the gonadal steroid biosynthetic capacity through
effects on cholesterol availability or the activity of the side chain cleavage
enzyme P450SCC.
Full
Abstract Here
The European Commission has reported that an application by Archer
Daniels Midland Corp to add phytosterols to such consumables as low fat milk,
yoghurt, and health food bars could easily cause consumers to be exposed to
levels more than twice the safe doses.
The report is here >>> >>… http://europa.eu.int/comm/food/fs/sc/scf/out192_en.pdf
and the
findings are at page 5. A new article
from Wise Traditions" the magazine of Weston A Price Foundation.
A new article from " http://bmj.bmjjournals.com/cgi/eletters/320/7238/861
... /
132
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
TOXINS ON YOUR TOAST
By Valerie James
; i ;
The latest buzzword in the food industry is
"neutraceuticals," plant-derived substances added to foods to make
them "healthier." This is the food industry's solution to the problem
of sluggish growth and declining profit margins on processed foods. There's
more money in pills containing "phytonutrients" like indoles or
isothiocyanates derived from broccoli, than in broccoli itself; and more profit
from "functional foods" like "energy bars" with added soy
isoflavones touted as a panacea for everything from menopausal symptoms to
osteoroposis, than from old-fashioned candy bars.
Recently the FDA allowed the industry the right to add
plant-derived sterols to such pedestrian products as vegetable oil spreads,
salad dressings, health drinks, health bars and yoghurt-type products. These
phyto-sterols include beta-sitosterol, campesterol and stigmasterol, all
estrogen-like compounds derived mostly from wood-pulp effluent. The products
will carry a health label claiming cholesterol-lowering properties, thanks to
FDA largesse, and consumers will pay highly inflated prices for the privilege
of spreading these known toxins on their morning toast.
"We really don't know how phyto-estrogens
act in the human body".
Dr Saffron Whitehead of St
; i ;
ADVERTISING BLITZ
"My father died young," says an earnest-looking man on a
television commercial. "When I found out I had a cholesterol problem, I
just thought, 'Well, I'm not waiting around for it to happen to me.' So I started
using Flora ProActiv margarine which actually reduced my cholesterol
absorption. With Flora ProActiv, I'm down from 6.5 to 4.5 in just three weeks.
Now I can do anything I've been wanting to do for years."
Not all consumers watch television. In fact, those consumers most
concerned about their health don't watch much television at all. They are
likely to get their nutrition information from newspapers and magazines.
Nutrition writers have been quick to comply with their advertisers' wishes with
articles on the virtues of functional foods. And the National Heart, Lung and
Blood Institute's "New Guidelines" for preventing heart disease
recommend the consumption of cholesterol-lowering margarines and spreads
providing 2 grams of sterols or stanols per day.
The cash registers are ringing up the dollars;
cholesterol-lowering phytosterols are already big business. Recently, the
pharmaceutical giant Novartis sold the licence for its phytosterol product,
Reducol, to Forbes Meditech, Inc. of
...
/ 133
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
TOXINS ON YOUR TOAST
By Valerie James
Continued
CONSUMER BEWARE
Just what are
phytosterols ??. They are hormone-like
compounds from plants, and they are present in large numbers in the effluent
from the wood pulp business. Canadian,
Phytosterols are a problem
for wood pulp processors because they are difficult to remove. For a time, in
the 1960s, they were able to cash in on them, as they were used as a basis for
commercial human sex hormones.(5). That use became obsolete
as even cheaper sources of waste products, derived from lanolin in sheep's wool
became available! Phytosterols also have the classic estrogenic effect of
stimulating the growth of uterine tissues, which may explain their folk-loric
use as abortifacients.(6).
There is a remarkable similarity between the chemical structure of
plant sterols and Diethylstilbestrol, the synthetic hormone associated with
reproductive cancers in women.(7). This is one reason
scientists seriously considered them as natural anti-fertility agents in place
of the modern synthetic contraceptive pill. This potential usage was abandoned
when phytosterols were found to have similarly harmful side-effects.
The National Research Council of the US Academy of Sciences has
warned about the potential of hormone exposure to humans from water downstream
from paper-mill effluent outflows (8), noting that these
compounds can induce feminization in male fish and cause the proliferation of
breast cancer cells.(9). Human studies have shown
that phytosterols are also osteolytic (10,11,12,13),
meaning that they cause a breakdown of
the organic bone matrix, and the subsequent leaching of the inorganic bone fraction
(14). This can lead to a life-threatening condition called
hypercalcemia, where the plasma level of calcium soars, an emergency situation
that occurs in about 40 percent of cancer patients.(11,15).
Hypercalcemia manifests initially as anorexia, nausea, vomiting
and abdominal pain. It is therefore no coincidence that Cytellin, a
now-obsolete phytosterol-based cholesterol-lowering drug, caused similar
adverse effects, listed in pharmaceutical texts as "anorexia, abdominal
cramps, and diarrhea".(16). In its more severe
manifestation, hypercalcemia results in emotional instability, confusion,
delirium, psychosis, stupor and coma, muscle weakness, cardiac arrythmias and
acute renal failure.
All authorities, including the FDA, should publicly and conspicuously
warn consumers that phytosterol-containing products are unsuitable for pregnant
or breastfeeding women, and for infants and children. This is because they
accumulate in the fetus by transplacental transfer.(17,18). As they
are fat-soluble, they can be found in breastmilk. Studies have shown that
phyto-sterols have adverse effects in ovarian structures, and also alter
follicular development(19); they work synergistically
with the natural hormone estradiol to promote anabolic effects(20), and to alter the sexual balance of the neonate's brain. It is an
accepted axiom that "the hormonal environment during the critical period
exerts permanent organizational effects that may affect the behavior in adult
animals"(21).
... / 134
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
TOXINS ON YOUR TOAST
By Valerie James
Continued
A recent Editorial in
the British Medical Journal has re-examined the
issue of "living in a sea of estrogens," and suggests "that the
apparent increases in the incidence of certain reproductive conditions may be
due to exposure to chemicals in the environment"(22). There is agreement that the incidence of testicular and prostate
cancer is increasing, and that semen quality is probably worsening in some
regions of the world. The increasing incidence of cryptorchidism & hypospadias in men
and endometriosis and polycystic ovaries in women is further evidence of
the damaging effects of environmental estrogens. Plant sterols added to
margarines will add to this load.
The effect of phytosterols on infants will be accentuated because
they accumulate in blood and tissues at a rate three- to fivefold above that
observed in adults(18). Once absorbed, they can
affect not only the hormonal environment, but can also be deposited in aortic
tissues of both infants and adults, resulting in atherosclerotic lesions(17).
Of course, industry interests would rather we do not know about
all this. Stan Correy of the Australian Broadcasting Company (ABC) comments,
"the days of an apple-a-day to keep the doctor away are over, because the
food companies have to move on from apples to make new profits. To give
credibility to these new products, they use scientists, doctors and people from
the legal professions to speak for them."
NEW
Not all government officials have bowed to the interests of the
food conglomerates. Dr Mark Lawrence of
Last September, ABC
devoted a full program to "The Twilight Zone: Medicalizing the Food
Supply," a program about the marketing of functional foods. Interviewer Stan Correy reported that the traditional food
industry has "hit the proverbial brick wall. It simply cannot make extra
profits by just selling plain grains, veggies and fruit; it has to find new
ways to tempt consumers to their products. It is no longer credible for the
food to be just delicious, especially if it is full of fat and bad things.
There is nowhere to go but to make it full of supposedly good things. Think
about it: fish oil in ice cream: it increases your memory; Brocco-bites, that's
broccoli in a pill; wood chips or cholesterol-lowering plant phytosterols in
margarine; all part of the wonderful 'healthy' world of functional food and
neutriceuticals." And of corporate profit motivation.
... / 135
- 135 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
TOXINS ON YOUR TOAST
By Valerie James
Continued
Negative media coverage of functional foods spurred us to fight
the introduction of sterol-added foods in
… http://www.soyonlineservice.co.nz/02phytosterols.htm . Their lengthy directive was condensed into a
strong press release reported in Australian and
… http://www.soyonlineservice.co.nz/BigBull/Big%20Ugly%20Bull.htm .
; i ; … In issuing the warning, Ian Lindermayer, ANZFA director, stated, "... we are certainly under those commercial pressures, that
is true, but we have a statutory duty that we take very seriously, to put the
protection of public health and safety at the very top of our priorities."
The ANZFA action sent
shock-waves not only through the Australasian food industries, but around the
world, because food companies hype a positive decision in one country to other
national food safety organizations. The industry initiated an extensive media
campaign, lobbied government officials, and even made a formal complaint about
ANZFA to the Australian Federal Senate. Despite industry efforts, ANZFA's
directive has become law in
Amazingly, the
industry has touted the ANZFA directive around the world as a
"success." Unilever launched an advertising blitz in the
In contrast with this
international activity, the
... / 136
- 136 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
TOXINS ON YOUR TOAST
By Valerie James
Continued
DANGEROUS AND ALSO USELESS
In 1990, Dr Petr Skrabanek of
The food industry believes it has found the Midas touch of turning
dross into gold, but for the trusting consumer sterol-added products are
nothing but fools' gold.
* As of
More information on our
Big Ugly
Bull page at ... http://www.soyonlineservice.co.nz/08biguglybull.htm
.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
... / 137
- 137 -
Dangers of Dietary Isoflavones
at levels above those found in traditional diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service
… http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm .
Continued
REFERENCES:
1. MacLatchy
et al, "The Phyto-Estrogen B-Sitosterol Alters the Reproductive Endocrine
Status of Goldfish," Toxicology & Applied Pharmocology 1995 134:305-312. Full Abstract Here
... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#MacLatchyVanDerKraak1995
.
2. Mellanen et al, "Wood-Derived
Estrogens: Studies in Vitro with Breast Cancer Cell-lines, and in Vivo in
Trout," Toxicology and Applied Pharmocology 1996
136:381-388. Full Abstract Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Mellanenetal1996
..
3. Howell
et al, "Gonopodial Morphogenesis in Female Mosquito-Fish Masculinised by
Exposure to Degradation Products from Plant Sterols," Environmental
Biology of Fishes 1989 24:43-51. Quotes
Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Howell&Denton1989
.
4. Denton
et al, "Masculinisation of Female Mosquito Fish by Exposure to Plant
Sterols and Micobacterium Spegmatis," Bulletin of Environmental
Contaminant Toxicology 1995
35:627-632. Quotes Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Dentonetal1985
.
5. Rydholm, Pulping Processes,
Interscience Publishing, 1965, pp
226-227 & 826-827. Quotes Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Rydholm1965
.
6. Farnsworth
et al, "Potential Value of Plants as Sources of New Anti-fertility Agents,
Part 1," Journal of Pharmaceutical Sciences 1975
64(4):583-587. Quotes Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Farnsworthetal1975a
.
7. Farnsworth
et al, "Potential Value of Plants as Sources of New Anti-Fertility Agents,
Part 2," Journal of Pharmaceutical Sciences 1975
64(5):737. Quotes Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Farnsworthetal1975b
.
8. "Hormonally
Active Agents in the Environment," National Research Council of the
American Academy of Sciences, National Academy Press 1999, pp 78 & 85. Quotes Here ...
at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#HormonallyActiveAgentsintheEnvironment
.
9. Makela
et al, "Estrogen-Specific 17B-hydroxysteroid Oxireductase Type 1C as a
Possible Target for the Action of Phytoestrogens," PSEBM 1995 208:51-59. Full Abstract Here...
- … http://www.soyonlineservice.co.nz/07abstract.htm#Makelaetal1995
10. Gordan et al, "Osteolytic Sterols
in Human Breast Cancer," Science 1966,
131:1226-1228.
No abstract available.
...
/ 138
- 138 -
Dangers of Dietary Isoflavones
at levels above those found in traditional diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service
… http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
REFERENCES: continued ...
11. "Tumor Sterols" Day et al in
Metabolism (18) (8) pp 646-650 1969. Full Abstract Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#TumorSterols
.
- http://www.soyonlineservice.co.nz/07abstract.htm
... Scientific Abstracts
12. "Identification
of Osteolytic Sterols in Human Breast Cancer" Gordan et al in Transactions
of the Association of American Physicians (53) pp 183-189 (1967).
Full Abstract Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Gordanetal1967
.
- http://www.soyonlineservice.co.nz/07abstract.htm
... Scientific Abstracts
13. "Significance
of Dietary Plant Sterols in Man and Experimental Animals" Subbiah et al in
Mayo Clin Proc (46) pp 549-559 (1971).
Quotes Here ... at ...
- http://www.soyonlineservice.co.nz/07abstract.htm#Subbiah
.
14. Taber's Cyclopedic Medical Dictionary,
18th ed, 1997, pp 1367. Description Here
- … http://www.soyonlineservice.co.nz/07abstract.htm#TabersCyclopedicMedicalDictionary
.
15. Merck Manual, 17th ed, 1999, pp 145-151. Quotes Here ... at
...
- … http://www.soyonlineservice.co.nz/07abstract.htm#TheMerckManualofDiagnosisandTherapy
.
16. Martindale, The Extra Pharmocopaeia,
28th ed, 1982, pp 411.
17. Mellies
et al, "Phytosterols in Aortic Tissue in Adults and Infants," Journal
of Laboratory and Clinical Medicine 1976 88(6):914-821. Quotes Here ...
18. Mellies et al, "Plasma and Dietary
Phytosterols in Children," Pediatrics 1976(57):60-67.
19. Samannoudy
et al, "Adverse Effects of Phytoestrogens-Effect of B-Sitosterol Treatment
on Follicular Development of Ovarian Structure and Uterus in the Immature
Sheep," Cellular and Molecular Biology 1979
26:255-266. Full Abstract Here ...
…
http://www.soyonlineservice.co.nz/07abstract.htm#Samannoudyetal1980
.
20. Mallini
et al, "Effect of B-Sitosterol on Uterine Biochemistry: Comparative Study
with Estradiol and Progesterone,"
Biochemistry and Molecular Biology International 1993 31(4):659-668.
...
/ 139
- 139 -
Dangers of Dietary Isoflavones
at levels above those found in traditional diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service
… http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
REFERENCES:
continued ...
21. Register
et al, "Effect of Neonatal Exposure to Diethylstilbestrol, Coumestrol and
B-Sitosterol on Pituitary Responsiveness and Sexually Dimorphic Nucleus Volume
in the Castrated Adult Rat" PSEBM 1995
208:72-77. Full Abstract Here ...
… http://www.soyonlineservice.co.nz/07abstract.htm#Registeretal1995
.
22.
23. Skrabanek, "Nonsensus
Consensus," The Lancet 1990
335:1446-1447.
24. Not listed in new website format in
fall 2005
* *
*
; Soy Online Service is appalled and horrified that Coca Cola would target children with such compounds
for profit. We are even more appalled that this is
occurring in the same year that the “European Commission” experts
calculated that daily exposures could be way beyond twice a safe amount ... Scientific
Committee on Food,
But,
we all know that the earth and money is the center of the universe, and
that the sun along with the soy industry and all of its supporters revolves
around the earth ??. Astronomer, Galileo 1564 – 1642.
"... Money, not truth, drives science – even at the expense of
the health and lives of the nation's citizens ...", by Dr. Phyllis Mullenix, Ph.D., formerly of Harvard
University, Dept. of Neuropathology and Psychiatry, See ... http://www.whale.to/b/fl2.html , and
http://www.lef.org/fda-museum/8_water/intarticles/fluoride-01-98.html
... Did Government Approve Citizens as Toxic Waste Sites ??, Are We Being
Poisoned ?? ... and it is no mistake !!.
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
Also see pages 98 and 100 -
115 and 142 - 144.
... / 140
- 140 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
REFERENCES: continued ...
... FURTHER READING ...
Plant Sterols in
Food
http://europa.eu.int/comm/food/fs/sc/scf/out192_en.pdf
The European Commission has reported that an application by Archer Daniels
Midland Corp to add phytosterols to such consumables as low fat milk, yoghurt,
and health food bars could easily cause consumers to be exposed to levels more
than twice the safe doses.
The report is here http://europa.eu.int/comm/food/fs/sc/scf/out192_en.pdf
... the findings are at page 5
Sections
3.4 Nutritional and toxicological
information
The applicant refers to the scientific literature and previous
evaluations of phytosterols. New
nutritional and toxicological information has not been provided.
4. Comment
The vegetable oil-derived
phyotsterol mixtures which are the subject of the present application do not comply fully with the phytosterol/phtyostanol profile of up to ... 80 %
B-sitosterol ... 15 % B-sitostanol ... 40 % campesterol ... 5 % campestanol ...
30 % stigmasterol ... 3 % brassicasterol ... and 3% other phytosterols ...
considered acceptable in general by the Committee (SCF, 2003). The amounts of the major sterols
B-sitosterol, campesterol, and stigmasterol as well as of B-sitostanol and
campestanol are in accordance with the accepted profile. The phytosterol mixtures can contain,
however, up to 6 % brassicasterol, 4 % delta 5-avenasterol and 5 % other
sterols, resulting in a content higher than 3 % for brassicasterol and 3 % for
total other phytoesterols. As brassicasterol
and other phyosterol esters of fatty acids were only minor constituents of the
phytosterol esters tested in the relevant toxicological studies (SCF, 2003) the
amounts must not exceed 3 %.
The applicant has not made
recommendations regarding the intake levels of phytoesterol containing
foodstuffs but relies on the assumption that normal consumption of the products
will provide the amounts necessary for plasma reduction and will not lead to
intakes above acceptable levels. However, the applicant’s estimate of the phytosterol intake, which is based on the production data of
the respective foodstuffs in eight Member States (Eurostat data) and on the
consumption data from one Member State (Dutch data), does not reflect the real consumption behaviour of an individual.
For example, in the case of yoghurt type products containing 3.3
sterols, a daily consumption of 30 or 39 g/person has been assumed, providing
1.0 or 1.3 g sterols/day, respectively.
As portion sizes for such products are usually 100 or 150 g, much higher
sterol intakes of 3.3 or 5.0 g, respectively, can result if only one portion of
a yoghurt type product is consumed per day.
In the case that more than one product is consumed, the actual sterol
intake can even be higher. For example,
the sterol intake from 150 g yoghurt and 25 g fat spread would amount to about
7 g/day.
... / 141
- 141 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Phytosterols
The new breed of wonder-chemicals ?.
. http://www.soyonlineservice.co.nz/02phytosterols.htm
.
Continued
REFERENCES: continued ...
... FURTHER READING ...
Plant Sterols in
Food
Continued
The European Commission Report
5. Conclusions
The committee has previously determined that the use
of “phytosterols” is safe provided that the sterol-containing foodstuffs are
not consumed in amounts resulting in total phytosterol intakes exceeding 3
g/day (SCF, 2002; SCF, 2003). In
principle, this can be applied also to the phytosterol and phytosterol ester
mixtures, which are the subject of the present application.
However, the mixtures can only be acceptable if the
composition complies with the phytoesterol/phyostanol profile accepted by the
Committee (SCF, 2003). Therefore, the mixture must not contain more that 3 %
brassicasterol and 3 % total other sterols (in addition to B-sitosterol,
campesterol, stigmasterol, B-sitostanol and campestanol).
The Committee reiterates the previous
recommendation that “...appropriate risk management measures should be
developed to minimize the likelihood of a daily intake exceeding 3 g
phytosterols/phytostanols, in particular from the cumulative intakes of
different types of products (SCF, 2002; SCF, 2003)...”. The Committee notes that the Commission is
working with Member States to develop such risk management measures.
In addition, the Committee wishes to draw the
attention to the point that in this application it is intended to add
sterols to beverages for the first time.
With regard to the sterol intake from such products, it should be noted
that portion sizes are difficult to control.
The Committee also reiterates the
recommendations:
A.) that
the small number of people with inborn error of phytoesterol metabolism
(phytosterolaemia) should be made aware of the presence of higher levels of
phytosterols in the product,
B.) that
patients on cholesterol-lowering medication should only consume the products
under medical supervision,
C.) that
the potential B-carotene lowering effect should be communicated to the consumer
together with appropriate dietary advice regarding the regular consumption of
fruits and vegetables.
The Committee notes again, that the
consequences of a persistently decreased blood concentration of B-carotene on
human health are largely unknown and that situations where Vitamin A
requirements are greater than normal as in pregnancy, lactation or infancy may
be of concern (SCF, 2002;
SCF, 2003).
Soy
Online Service Home … http://www.soyonlineservice.co.nz/index.htm
.
DNA
and Immune System damage … http://www.soyonlineservice.co.nz/04immunefunction.htm .
Hot
News ... Just Off The
Press … http://www.soyonlineservice.co.nz/02hotoffthepress.htm
.
Weston
A. Price Foundation … http://www.westonaprice.org/ . ... /
142
- 142 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
95.x "...
Imagine having drugs added to our food which have been scientifically
proven, for nearly 25 years, to be carcinogenic and to also cause
DNA and chromosome damage in both humans and in animals. Also, imagine these drugs being
prescribed and administered through our food supply without the individual’s prior
knowledge or understanding of these dangers, or prior consent to be exposed to these
dangers. Now, imagine the entire population in many countries around
the world, including ours, consuming these foods ... with no medical way of
tracking dosage, individual reactions, or harmful side-effects, and, without
any concern for some people’s increased vulnerability from being exposed
to these drugs, such as cancer patients.
Does all this sound a little
crazy ??. Well, I’ll tell yeah,
this is exactly what is happening to us when Soy is added to our food supply. Soy contains the “naturally toxic” ingredients genistein and daidzein which have been scientifically
documented, proven, to be carcinogenic, cause DNA and chromosome damage, and to cause
cancer cells to grow. Soy can also cause non-cancerous tumors to turn cancerous
...”. Soy does all this and more, as these are only
some of the many health hazards associated with eating soy. To
protect your health and your families health, be sure to read the ingredient
labels on all of the foods you buy. Also, be very, very careful about eating in “Restaurants”
and in “Hospitals”, as they do not list the ingredients in their
foods. Vegetable oil
is no longer vegetable oil ... it’s either “Soy”, or “Canola”, or both.
P.S.
The above paragraph was adapted and modified from the 1 st.
paragraph in this weeks, Sept 10, 2003, Dr.
Joseph Mercola's newsletter article called ... "What You Never Expected
to Hear About Water Fluoridation,"
at ... http://www.mercola.com/2003/sep/10/water_fluoridation.htm,
“... Imagine a drug being prescribed to the entire
The End ??.
There is no END to Truth !!.
“The Truth
Marches On” ... Emile Zola, ... and “The Dreyfus
Affair” ... in France, 1894 - 1898 ... and author of many good
books, at... http://www.georgetown.edu/faculty/guieuj/libproj.htm
and http://www.dreyfuscase.com/html/dreyfus_affair.html
, others
“Ethics”
... n. pl., 1.) The Principles of morality, including both the
science of the good and the science of right. (Also see pages 100 - 4)
Can
you do the "right thing", even if it means challenging the authority figures and
rules of the day, and then do it again, and again and again ??. Are you strong enough, and do you have the “Courage” to follow Socrates
example of what …
Socrates (469-399 BC) said about Courage ... “Examine your thoughts, statements and
actions by pursuing their implications, on the assumption that if they are
true, they would not lead to false consequences,” and about …
“Humanitarian
Action” ... “Choose
wisdom so that society is incapable of doing wrong.”
Einstein
Said, “... The world is a
dangerous place to live in, not
because of the people who are evil, but because of the people who don’t
do anything about it ...”.
Neapolitan
said, “… Morality is on
the side of those with the heaviest artillery !! …”. Well, just look what
happened to Neapolitan, to The Roman
Empire and even to ancient Egypt. Or is
it, “… them that has the most gold makes the rules ?? …”. On
the other hand, has it really been all along about finding ways to use
“might for right”. What a novel
and old-fashioned idea.
Do
you have the “Courage” to
play your part in putting an end to this type of activity in our
society described in the sentence below?? …
“... Money, not truth, drives science - even at the expense of the
health and lives of the nation’s citizens ...”, by Dr. Phyllis Mullenix,
Ph.D., formerly of Harvard University, Dept. of Neuropathology and Psychiatry, See ... http://www.whale.to/b/fl2.html ...
and ... http://www.lef.org/fda-museum/8_water/intarticles/fluoride-01-98.html
... Did Governments Approve Citizens as Toxic Waste Sites ??, Are
We Being Poisoned ?? ... and it is no mistake !!.
If you do, then
you have been able to touch the ! Heart and ! Love of God with your ! Heart,
with your thoughts, and with what you have said and done with your life on
earth ... this time ... and then each time hereafter. ... / 143
- 143 -
Written In Memory of Princess Diana and
Mother Teresa,
Sept. 1997
The ! Heart
Has No Reasons, It Knows Without Reasoning.
When all is said and done,
when you come to the end of your life, I don't
want to know what the world
said or what your worldly mind has learned
to define as successful, or
what rules or customs you were brought up with
and felt you had to follow in
order to justify what you did or didn't do to
others or for others. What I really want to know is, Do you know
how
to really not know ??. Can you realize your own ignorance while you
profess and assert your
worldly knowledge to others ??. I want
to know
if you have learned what it
means to think with and through your Heart, to
know the difference between
looking with your eyes and seeing with and
through your Heart, and to not
only be able to hear with your ears but to
also be able to listen with
and through your Heart. Have you learned
and experienced the
difference between feeling with your hands and
feeling with and through your
Heart ??. Are you able to touch others
Hearts with your Heart ??.
I don't want to know what
facts you have learned throughout your life on
earth, but I do want to know
if you know what it means by the saying, "The
!
Heart has no reasons, it knows without reasoning". Have you learned
how to know with and through
your ! Heart ... FIRST, and then act
accordingly ??. I want to know if you can do the "Right Thing", even if
it means challenging the authority
figures and rules of the day, and then
do it again, and again
??. What I really want to know is, are you strong
enough, and do you have the courage to follow Socrates, ( 469 - 399 BC ),
example
of "... Examining your thoughts,
statements and actions by
pursuing
their implications, on the assumption that if they are true,
they
would not lead to false consequences ..." ??. I want to know that
after you have struggled to
climb, to ascend, to the top of the mountain,
will you willingly and Joyfully and ! Lovingly come back down
to be
with and to help those who
have not climbed the mountain ??. If you
can, then you have been able
to touch the ! Heart and ! Love of God
with your ! Heart, with your
thoughts, and with what you have said and
done with your life on earth
... this time ... and then each time hereafter.
Anonymous
P.S. The ! Heart
has no reasons, it knows without reasoning, because the ! Heart
understands and knows in ways that reason does not understand and can
not verify . . . so, the ! Heart
has it reasons that reason does not know.
Einstein
Said, “... The world is a
dangerous place to live in, not
because of the people who are evil, but because of the people who don’t
do anything about it ...”.
“Ethics”
... n. pl., 1.) The Principles of morality,
including both the science of the good and the
science of right.
... / 144
- 144 -
The Water Bearer
A water bearer
in China had two large pots, each hung on the ends of a pole which he carried
across his neck. One of the pots had a
crack in it while the other pot was perfect and always delivered a full portion
of water. At the end of the long walk
from the stream to the house, the cracked pot always arrived only half full.
.
For a full 2
years this went on daily, with the bearer delivering only one and a half pots
of water in his house. Of course, the
perfect post was proud of its accomplishments, for which it was made. But the poor cracked pot was ashamed of its
own imperfections, and miserable that it was able to accomplish only half of
what it had been made to do.
.
After 2 years of
what was perceived to be bitter failure, the cracked pot spoke to the water
bearer one day by the stream. “I am
ashamed of myself, because this crack in my side caused water to leak out all
the way back to your house.
.
The bearer said
to the pot, “Did you notice that there are flowers on your side of the path,
but not on the other pot’s side ??.
That’s because I have always known about your flaw, so I planted flower
seeds on your side of the path, and every day while we walk back, you water
them. For 2 years, I have been able to
pick these beautiful flowers to decorate the table. Without you being just the way you are, there
would not be these beauty to grace the house.”
.
Each of us has
our own unique flaw. But it’s the cracks
and flaws we each have that make our lives together so very interesting and
rewarding.
Margins for main Soy Research Paper,
Pages 1 to 144 , and to 168
Top … 0.40
inches
Base
Font Type … Times New Roman and Arial
Bottom …
0.30 inches
Base
Font Size … ( 9, 10, 11, 12, 14, 16, 18, 20,
Left … 0.50 inches Right …
0.25 inches 22,24, 28, 30, 32, 36 )
Justification … Full ...
/ 145
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
. .
Ethics and Soy
Please
refer to page 5, 12, 18, 98-105, 109, 113, 114, 119, 143-152
of
this Soy Research Paper
Putting soy in our food
supply, medications, vitamins and mineral supplements, and in the food of our
pets and farm animals is force feeding a poisonous ingredient
on to the public, and our pets and farm animals without consent.
Very much the same type
of reasoning and logic can be use for not putting soy in our food supply as is
used in not putting fluoride in our food supply.
In this research paper,
it has been established that putting soy and soy ingredients in our food supply
is not legal.
It has been established
that soy estrogens are a drug.
It has been established
that soy is
proven to be and is classified scientifically as a Topoisomerase II-poison .
Medical ethics unequivocally
demands that the wishes of the individual must take precedence over actions
imposed by the state, medical system, or corporation, unless there is a
valid and wider public health concern.
Putting soy in our food
supply is forcing a person … without their consent … to take a medication … as
well as … forcing a person to take a know and proven poison with very serious
and sometimes deadly health hazards … It is mass poisoning.
Putting soy in our food supply is illegal mass
medication without consent. It is an abuse of our human rights and also breaches Human
Rights legislation, Putting soy in our food forces the public to consume an
unlicensed substance and a substance that has been tested and proven to cause
over 24 very, very serious and sometimes deadly adverse health effects
including cancer and heart disease and death.
Putting soy in our food supply does
not allow a person to avoid it if they have a medical condition that soy will
make worse.
Putting soy in our food
supply removes people's fundamental
Human Right to refuse medication, removes freedom of choice.
The reality is that our
food supply is being poisoned with a poisonous soy ingredients that cause over
24 very serious and sometimes deadly health hazards.
It has been proven that
there is no real proven benefit to eat soy.
There is only one real reason for putting soy and soy ingredients in our
food supply and that is … for the express purpose and the intent to harm others. This is just like the intent to harm when
someone puts a razor blade, pin, etc in a apple or candy at Halloween. The
intent to harm. With all the alternatives available for the reasons that are
given to put soy and soy ingredients in our food supply, one can easily and
understand that there is no other reason but to want to harm large and mass
amounts of people, by people with bad motives, including putting profits above
the health and safety of others.
Soy robs us of our freedom to choose &
violates the … The Code of Medical Ethics -- set out in the Council of Europe's Convention on Human
Rights and Biomedicine … Codex Soy Food Safety Standards … Precautionary Principle
… FDA GRAS … “Declaration of Helsinki” … “Nuremberg Code “…
Hippocratic Oath … First Do No Harm.
The ethical validity of the policy
of putting soy ingredients in our food supply does not stand up to scrutiny
relative to the Nuremberg Code and other codes of medical ethics, including the Council
of Europe's Biomedical Convention of 1999. The police power of the State has
been used in the United States to override health concerns, with the support of
the courts, which have given deference to health authorities.
Continued
… ...
/ 146
- 146 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Ethics and Soy
Please
refer to page 5, 98-103, 113, 114, 119
of
this Soy Research Paper
Continued
Soy And The Ethics Of Medical Research
… Clearly,
the investigation of the effects of soy on large populations must be regarded
as medical research, since their full health implications are unclear even as
their efficacy in terms of their primary objective is coming under increasing
challenge.
Medical Malpractice Intervention Without Consent
… In the case of
any state medical intervention, each person exposed is regarded as a patient,
and must be accorded his or her full rights as such. Failure to do so
constitutes medical malpractice. Yet there has been no example of fluoridation
of the public water supply in which every member of the public living in, or
visiting, a target area has been informed, directly and individually, by the
state or by its medical agents at any level, of the risks they may personally
face from any of the known adverse effects of water fluoridation.
*
* *
*
* *
Page 5 of this Soy Research Paper …
The Soy industry has “applied twice” and was “turned down twice(1979, 1999)” on both of its applications for “GRAS
(Generally Recognized As Safe)” status for Soy Protein BECAUSE of Soy’s carcinogenic properties;
also Soy has not been given
“Pre-market Approval” for its use in our
food. It is not even legal to add it to
our food.
In addition, Soy is in breach of, in violation
of - “WHO/CODEX - Food Safety Standards.” P.S. To add insult to injury, Soy fails the 1958 “Delaney Amendment” to the USA’s FDA
Reg.’s which prohibits the use of any food additive if it is found to cause
cancer in any animal species or in man, at any dose level ... http://www.pcdf.org/meadows/delaney.htm
. Add these 6
strikes against the Soy industry to the growing list of ignored
side-effects on page 1., and you have millions of crime scenes.
In the US
FDA’s “Poisonous Plant Database” … http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY ... Soy, and
(Flax and Linseed), and (Canola, and
Rapeseed) are all listed as “poisonous plants”, and the FDA recommends
that if you are injured by them, to contact your local “Poison
Control Center” in your area, (at ... http://www.aapcc.org/.),
or call 911. Soy acts like a fertilizer
and fertilizes, feeds, cancer cells to help them grow.
*
* *
*
* *
References
:
… http://www.calderdale-online.org/html/community/fluoride.html
... Community Action … Support the campaign to stop your
water supply being illegally poisoned with fluoride.
… http://www.rvi.net/~fluoride/000038.htm ... Fluorides
and Fluoridation … Fluoridation: A Violation of Medical Ethics and Human Rights
… by Douglas Cross and Robert J. Carton, PhD … International
Journal of Occupational Health 2003;9:24-29
… http://www.soyonlineservice.co.nz/
… Soy Online Service
… http://www.westonaprice.org/splash_2.htm
... Weston A. Price Foundation
… http://www.thewholesoystory.com/index.php
... The Whole Soy Story, 2005, by Kaayla T.
Daniel, PhD, CCN
...
/ 147
- 147 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
.
HOT - HOT ... SUPER RED HOT
An FDA
Historical Event
( 3 Parts ) - Soy Industry
badly burned
when confronted with the ignored and still
denied scientific PROOF
The Hidden TRUTH
"Soy Causes Cancer !!,"
and many other very, very
serious health problems!!.
On
asking the
.
.
Red - Red Hot ... Part 3 of 3.
.
-----
Original Message -----
From: Valerie & Richard James ... Soy Online Service ... http://www.soyonlineservice.co.nz/ .
To: wholenutritionist@earthlink.net ... The Whole Soy Story ... http://www.thewholesoystory.com/index.php .
Cc: Mike Fitzpatrick ; Gerald
Hernesmaa
Sent:
Subject: Re: Re: For our website "RED HOT": Solae withdraws
soy/cancer petition Also link to "Cancer" "Male Health",
and "Your Baby"
Hi Kaayla.
Yes, they will be
back in a new disguise. Like the time we
got ADM outed ( or should I say "withdrawn" ) on the isoflavone GRN
00001 application, Cargill then popped up like a fairground dummy and slipped
Novacrap past us all.
Cheers Dick
........................................................................................................................................................................................................................................................................................................................................................................................................
-----
Original Message -----
From: Kaayla Daniel ... The Whole Soy Story ... http://www.thewholesoystory.com/index.php .
Sent:
Subject: Re: For our website "RED HOT": Solae withdraws
soy/cancer petition Also link to "Cancer" "Male Health",
and "Your Baby"
It's a
brilliant corporate spin. It's
good news for us, of course, that we all had an impact and that we stopped
this fraudulent health claim, but Solae's retreat will effectively
prevent any media attention.
We, of course, are claiming victory -- I have big New York PR Agency set to run tomorrow with "Dr.
Daniel vs. SoyLiath: Soy Industry Giant Withdraws from FDA Health Claim Battle.
" But the bottom
line is - that it has far less news value than the FDA turning them down
I won't be on TV,
we won't sell any extra books -- and Solae will carry on business as
usual.
Kaayla
Part 3 … contined … /
148
- 148 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Red - Red Hot ... Part 3 of 3.
… continued
-----
Original Message -----
From: Valerie & Richard James ... Soy Online Service ... http://www.soyonlineservice.co.nz/ .
To: wholenutritionist@earthlink.net … The Whole Soy Story … http://www.thewholesoystory.com/index.php .
Sent:
The corporate
spin is that the FDA changed the rules.
The truth is that
the Dupont/Bunge joint venture named Solae filed a fraudulent applocation with
the US FDA for approval of advertising that soy isoflavones can prevent cancer.
Soyonlineservice filed an objection based on published science that shows that
soy isoflavones can cause cancer. We were joined by hundreds of other objectors
Solae have now tossed in the towel and run away.
See our comments
on “the lowest form of life” in Phytoestrogens..Cancer.
… http://www.nutraingredients-usa.com/news/ng.asp?n=62956-solae-soy-cancer-health-claim .
Solae withdraws soy/cancer health claim petition
..
* *
*
* *
*
.
Red - Red Hot ... Part 2 of 3.
.
-----
Original Message -----
From: Valerie
& Richard James ... Soy Online Service ... http://www.soyonlineservice.co.nz/ .
Cc: greg@soyatech.com ; joe@soyatech.com ; customerservice@soyatech.com
; Gerald Hernesmaa
Sent:
Subject: Solae Temporarily Withdraws FDA Health Claim Petition;
Hello folks.
If you tread the
FDA file ... http://www.fda.gov/ohrms/dockets/dockets/04q0151/04q0151.htm
... you will find that several hundred
objections to Solae's claims were filed citing science that
shows that isoflavones cause various cancers.
Tell the
truth......that DuPont and Bunge ( major financial investors-players in Solae and also
directly connected to the world-wide Soy industry via
the pharmaceutical industry ) were ALL sent running with their
tails down.
Valerie
…
* *
*
* *
*
… /
149
- 149 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
.
Red - Red Hot ... Part 1 of 3
.
-----
Original Message -----
From: Valerie & Richard James ... Soy Online Service ... http://www.soyonlineservice.co.nz/ .
To: Gerald Hernesmaa
Sent:
Subject: Re: Re: ... ... Re: Solae Press Release
Hi Gerald
AH1 You've
learnt a lot !!. A very likely scenario indeed. Do you still have
the link to the Soy Information Service submission on the FDA website?
Cheers, Dick.
..............................................................................................................................................................................................................................................................................................................................................................................................................................................................
-----
Original Message -----
From: Gerald Hernesmaa
To: Valerie
& Richard James ... Soy Online Service ... http://www.soyonlineservice.co.nz/ .
Sent:
Subject: Re: ... ... Re: Solae Press Release
.
Hi ... Richard
and Valerie James
From ... Gerald Hernesmaa
Thank you for
sending me this email.
I think that Solae
withdrew its application in order to have behind the scenes help from the FDA
in rewording and resubmitting it again, similar to 1999 ??.
Do you think this
is probably the case ??.
Gerald
..............................................................................................................................................................................................................................................................................................................................................................................................................................................................
-----
Original Message -----
From: Valerie & Richard James ... Soy Online Service ... http://www.soyonlineservice.co.nz/ .
To: wholenutritionist@earthlink.net ... The Whole Soy Story ... http://www.thewholesoystory.com/index.php .
Cc: Gerald Hernesmaa
Sent:
Subject: Re: Solae Press Release
Hi Kaayla.
Whoopee-dee-doodah!!
However, they are still lying bastards, or their confidence is based on sheer
idiocy.
Cheers, Dick.
Part 1 … contined … /
150
- 150 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Red - Red Hot ... Part 1 of 3.
… continued
-----
Original Message -----
From: Kaayla Daniel ... The Whole Soy Story ... http://www.thewholesoystory.com/index.php .
Sent:
Subject: Re: Solae Press Release
Media Room - News Release
For more information, please contact:
Geri Berdak, Director of Public Affairs
The Solae Company
314/982-2588
and/or
Chris Short or Whitney Smith
Cushman/Amberg Communications, Inc.
312/263-2500
THE SOLAE COMPANY TEMPORARILY WITHDRAWS FDA
HEALTH CLAIM PETITION
Soy Protein Manufacturer Cites Change in Evaluation Process as Catalyst for
Decision
St. Louis, MO
(September 30, 2005) –
The Solae Company today announced it is temporarily withdrawing its request for
a qualified health claim related to soy protein consumption and cancer
prevention. The Solae Company made its decision after an analysis of recent FDA
health claim decisions.
The company
believes the relationship between consumption of soy protein and the prevention
of cancer is strong but withdrew the claim because it felt the FDA’s process is
new and its evaluation process is evolving. By making sure the petition meets
current criteria required for the restructured evaluation process, The Solae
Company will be putting forward the strongest possible case based on the
science for the FDA. The company’s objective in filing this petition was to
enable research-based health information to be made more readily available to
consumers.
“Our decision has
nothing to do with our confidence in the science,” said Dr. Greg Paul, director
of health and nutrition for The Solae Company. “We have an improved
understanding of the process and have decided to withdraw the petition and
re-structure it so it will be in-line with the FDA’s current qualified health
claim process.”
Nearly 60
different independent research studies support the relationship between the
consumption of soy protein-based foods and reduced risk of developing several
types of cancer, and new studies continue to investigate such a link. For
example, a study in this week’s Journal of the American Medical Association
found that higher consumption of some soy products is associated with a reduced
risk of lung cancer.
As leaders in the
industry, The Solae Company will continue to spearhead research exploring the
health benefits of soy protein and will continue to seek ways to communicate
those benefits to consumers. The company plans to re-submit the petition to the
FDA at a later date but no specific timelines have been set..
Headquartered in
The End of Red Hot Parts 1,
2, and 3
… /
151
- 151 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
-----
Original Message -----
From: Valerie
& Richard James ... Soy Online Service ... http://www.soyonlineservice.co.nz/ .
To: editorial@alive.com ; Gerald Hernesmaa
Sent:
Subject: Fw: SOY BABY FORMULA WARNING IN --
BMJ
SENT TO YOU
BY www.soyonlineservice.co.nz. Please circulate this knowledge
.
British Medical Journal,
Health committee warns of potential dangers of soya
©
2005 BMJ Publishing Group Ltd Volume 331(7511),
. http://bmj.bmjjournals.com/cgi/content/extract/331/7511/254-a .
[News: News roundup]
Jerusalem, by Judy Siegel-Itzkovich
Israeli
manufacturers of soya products were rattled by the recommendation issued by the
country's health ministry that consumption of soya products be limited in young children and
avoided, if possible, in infants. After a year's work, a
committee of experts also advised that adults who eat soya products do so in
moderation, pending authoritative future studies. Although research showing
possible harm;a higher risk of cancer, male infertility, or other problemsfrom
soya is based on animal or retrospective human studies, the committee of 13 issued recommendations
based on the precautionary principle. Soya contains
phytoestrogens that may have some of the effects of the human hormone if
consumed in large quantities. Soya consumption is high in
Since soya provides cheaper protein than meat, it is widely served in various
forms, especially in day care centres that are spared from using separate
dishes and cutlery. Soya burgers made from reconstituted flakes and other
forms, many of them developed by Israeli companies, as well as tofu and misu,
are popular among health conscious people. "We don't know the long term
effects on health of large amounts, so we are urging moderation," said
Dorit Nitzan Kaluski, director of the health ministry's food and nutrition service
who was a committee member. "We want to be careful. And while it is easy
to identify soya products, there is much more soya added to foods such as
breads, cakes, cookies, and crackers." Paediatricians will monitor the
thyroxine concentrations in infants and toddlers who have hypothyroidism who drink
soya based formula or soya foods. And women with breast cancer or a high risk of it
will be advised to consult their doctors about soya in their diets.
Dr Nitzan Kaluski said that to avoid pressure from soya food firms,
the committee did not inform them in advance,
but within a day of the report's release, she received at least one lawyer's
letter and numerous requests for information. She expects lawsuits are on the
way.
Accession
Number: 00002591-200507300-00022 , Copyright (c) 2000-2005 Ovid Technologies, Inc. , Version: rel10.0.0, SourceID
1.10844.1.117
Warning - 2
years to late … You will notice that the article is very cleverly worded in
order to avoid, in order to leave out, WHY the Israeli government committee issued the
warning in the first place ... which is ... 3 Israeli baby died and 17 other Israeli babies got
severe permanent brain and nervous system damage from soy infant formula in the
summer of 2003.
HAARETZ.com on Nov. 9, 2003 … http://www.haaretzdaily.com/hasen/pages/ShArt.jhtml?itemNo=358387&sw=Soy-based …
“Health Minsitry probing possible ( Soy ) baby-formula
deaths”
MSNBC on Nov.10, 2003 … http://msnbc.msn.com/id/3404430/ …
“Infant deaths linked to baby formula - Israel opens investigation into
German-made ( Soy ) product”
… /
152
- 152 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
-----
Original Message -----
From: Valerie
& Richard James ...
Soy Online
Service ... http://www.soyonlineservice.co.nz/ .
To: editorial@alive.com ; Gerald Hernesmaa
Sent:
Subject: Fw: MOTHERING MAGAZINE REPORTS
ISRAELI DECISION
AN ARTICLE FROM "MOTHERING” MAGAZINE ,
Please spread the
knowledge around
Israeli Health Ministry
Issues Soy Warning
. http://www.mothering.com/sections/news_bulletins/august2005.html#soy
.
August 2005
Scientists,
doctors and nutritionists who have warned that soy is not a health food and poses special risks to infants and children–
received support recently from the Israeli Health Ministry, which issued a
health advisory recommending that soy foods be eaten only in moderation. The
Israeli Health Ministry strongly recommended that consumption of soy foods be
limited for young children and adults and that soy formula be avoided altogether by infants,”
said Kaayla T. Daniel, PhD. Dr. Daniel noted that there are hundreds of studies
linking soy foods and soy infant formula to digestive problems, thyroid
dysfunction, ADD/ADHD, dementia, reproductive disorders and even cancer. The
Israeli Ministry took this matter very seriously and based its advice upon the
conclusions reached by a 13-member committee of nutritionists, oncologists,
pediatricians and other specialists who spent more than a year examining the
evidence. The committee concluded that the estrogen-like plant hormones in soy can cause adverse
effects on the human body, including cancer promotion and reproductive problems. They strongly urged that consumption of soy foods be
minimized until absolute safety has been proven.
According
to the Jerusalem Post (July 20), soy is widely used in Israel by people of all
ages because it is a cheap substitute for meat and soy infant formula is
especially popular among haredi families who choose not to mix milk-based baby
formulas with meat meals. The Health Ministry plans to distribute information
about the dangers of soy foods and soy infant formula to pediatricians, health
care workers and the public. It firmly recommends that babies that cannot be
breastfed receive cow's milk formula and be given soy infant formula only as a
last resort. The Israeli Health Ministry's recommendations are in accord with
those made by the United Kingdom's Chief Medical Officer and the British
Dietetic Association, both of which have alerted pediatricians and parents to
use soy infant formula only in unusual circumstances,” said Dr. Daniel. In
Although
the Israeli Health Ministry stopped short of making recommendations on soy
consumptions for adults, it found that the evidence on soy foods alleviating
menopausal symptoms is inconsistent, that soy phytoestrogens can increase
breast cancer risk and that they can reduce male fertility. The Ministry determined that soy
has been shown to reduce blood cholesterol but stated that there is no clear
proof that it reduces the risk of heart disease.
"The bottom line," said Dr. Daniel "is that the Israeli
Health Ministry looked long and hard at the evidence and reached the
appropriate conclusion that we should eat soy only occasionally and in
moderation because possible benefits are
far outweighed by proven risks."
…
Warning was - 2 years to late … You will notice that the
article is very cleverly worded in order to avoid, in order to leave out, WHY the Israeli government
committee issued the warning in the first place ... which is ... 3 Israeli baby died and 17 other Israeli babies
got severe permanent brain and nervous system damage from soy infant formula in
the summer of 2003.
HAARETZ.com on Nov. 9, 2003 … http://www.haaretzdaily.com/hasen/pages/ShArt.jhtml?itemNo=358387&sw=Soy-based …
“Health Minsitry probing possible ( Soy ) baby-formula
deaths”
MSNBC on Nov.10, 2003 … http://msnbc.msn.com/id/3404430/ …
“Infant deaths linked to baby formula - Israel opens investigation into
German-made ( Soy ) product”
*See the 2 - one page Soy summary pages below … on pages
153 – 156 .
Warning
- Soy Damages
Your Thyroid, Immune System, DNA and Chromosomes
. http://www.soyonlineservice.co.nz/ . (( healthwise933@shaw.ca ))
Soy
has not → does not → can not → Soy will not →
prevent cancer Gerald and Deanna
- ( Deonaa )
Soy
blocks vitamin, mineral, protein absorption ( Osteoporosis ) … pages 84, 96
Soy damages the Myelin Sheath around the nerves, spinal cord and brain
tissue … pages 63 - 67
Genistein in soy is proven to be and is
classified as a Topoisomerase II-poison …
pages 32, 42, 44, 71-2, 81
Soy causes cancer → → Soy causes existing cancer cells to grow → → Soy causes non-cancerous tumors to turn cancerous
Soy is an Omega-6 oil, fatty acid, and
they → “cause” cancer cells to grow … http://www.mercola.com/2002/jun/5/fish_oil.htm,
British J. Nutr., Apr. 2002, vol.87:4, pp. 281 - 289(9) and vol.87:3, pp. 193 - 198(6).
* Read the fine print
. .
Soy was the major contributing cause of my wife Deanna-(Deonaa)
death from Breast cancer, Bone cancer, and Liver cancer on
.
The US FDA's … "Poisonous Plant and Plant Parts
Database," at … http://vm.cfsan.fda.gov/~djw/pltx.cgi?QUERY=SOY , and http://www.cfsan.fda.gov/~djw/plantox.html
… documents --- Soy – Flax-Linseed –
Canola-Rapeseed -- as “poisonous plant,” Soy since 1907
and Flax since 1850. The FDA recommends that if you are injured by these plants, to contact
your local “
.
“Soy – Abundance of
Health Hazards”
identifies the link to the over 144 page Soy Research Paper,
which can now be found in the Health Section under Articles on the “Mayan Majix” website at … http://www.mayanmajix.com/art_ht.html
, and at … http://www.mayanmajix.com/soy.html
… Dangers of Soy
- http://www.mayanmajix.com/soy_summary.pdf … Short one page Summary PDF -
http://www.mayanmajix.com/soy01.html
… Full 144 page HTML
- http://www.mayanmajix.com/soy_306.pdf … Abundance Scientific Proof - Summary - http://www.mayanmajix.com/soy01.pdf … Full 144 page PDF
containing a collection of over 205 scientific research abstract
summaries on Soy … pages 29 -
96, from almost 1,800 going way back to 1907,
( also see the 2005 book “The Whole Soy Story” ) … that are from well-designed studies,
from around the world, conducted in a manner
which is consistent
with generally recognized scientific procedures and principles which
show that - there does exist
- significant scientific agreement among research
experts from around the world, {
qualified by scientific training, experience and expertise }, PROVING a very
strong statistically significant association of very serious harm to human and
animal health from consumption of soy, SPI-soy protein and soy estrogen ingredients in our food supply &
an INCREASED RISK of a
variety of cancers and other major and life threatening health problems,
referred to in this body of evidence as …
“Hidden Harm” …
which includes, but is not limited to this list of known, “ignored,” still
denied “Side-Effects”
of ... endocrine disruption ... thyroid suppression
... immune system suppression ... Liver disease
... ♥ Heart disease ... leukemia,
( IAL ) ... subtle changes in sexually dimorphic
behaviors ... Arthritis ... infertility / lower sex
drive ... growth problems
... learning disabilities // Alzheimer’s – Parkinson’s Disease // M.S. -- from
Brain & Nervous System damage ... Osteoporosis
... as well as
... chromosome fragmentation & errors in chromosome orientation ... Cancer(s)
- breast, bone, uterine, liver, colon, pancreas, thyroid etc
... DNA damage ...“DEATH”...
(+) infinite # of - “broken ♥ Hearts”. ( Many “Research Experts” say in the
conclusion of their abstracts … Women with cancer or a history of
cancer should be warned ... pgs. 5-10, 17-8, 37, 40, 47, 52,
55, 73, 77, *80, 122, & 60, 72, 77.)
.
– http://www.mercola.com/2002/jun/8/soy.htm … “Soy Weakens Your Immune System” … Soy
Industry own research
2002
… “The phytoestrogen genistein induces thymic and immune changes: a human
health concern ?,” ( *see page 55 )
( Yellayi S., Naaz A., Sato T., Woods J.A., and others --- Proc Natl Acad Sci USA 2002 May
28;99(11):7616-21 ) … Dr. Mercola’s
Comment -- “It is quite
amazing that this study was actually published, as the findings were quite
negative for Soy, yet it was funded by United Soybean
Board and
. It
is like throwing gasoline on a campfire.
…“Meta-Analysis”…
– http://www.mercola.com/article/soy/avoid_soy.htm
… A “meta-analysis” is a review & summary of the results of many clinical
studies on the same subject. The use of
meta-analyses to draw general conclusions has come under sharp criticism by
members of the scientific community. "… Researchers substituting
meta-analysis for more rigorous trials risk making faulty assumptions and
indulging in creative accounting …", says Sir John Scott,
President of the Royal Society of New
.
There
is a added temptation for researchers, particularly researchers funded by
companies like Protein
Technologies International – soy corporation, to leave out studies that contradict / dilute the
conclusions desired … see W.A.P.F. 2004
submission of objection to the US F.D.A. - 2004Q-0151, page 10, ( being that soy has many very serious
health hazards ). Dr Anderson discarded 8
important studies for various
reasons, leaving a remainder of 29.
-- See
and … http://www.westonaprice.org/soy/solae_comments.pdf
… and … Soy Alert … http://www.westonaprice.org/soy/index.html
.
Another
very good example … It was a 1994 meta-analysis by Mark Messina that fueled False speculation that
soy had anti-carcinogenic properties, published in Nutrition and Cancer..43. ( and yet, it is
this very same paper that proves Soy has been “known” in scientific community … to be carcinogenic for over 40 years … cause DNA - Chromosome damage for more than 25 years … cause infertility for 50 years … thyroid damage for 70 years … page 126.)
…
..
.
* *
*
.
New Margins – for pages 153 and 154
“Warning - Soy Damages Your Thyroid, Immune System, DNA and Chromosomes
By adjusting only pages 153 and 154 to these margins below, this
one page summary will all fit on one page in MS Word.
Top … 0.20 inches
Bottom … 0.20 inches
Left … 0.26 inches Right … 0.25 inches
Base Font Type … Times New Roman
Base Font Size … ( 8, 9, 10, 11, 12, 14 ) ,
( 8 pt for spacing between title and first line, and 6pt spacing between other paragraphs )
Justification … Full
Note: Make sure the label on your vitamins, minerals, and medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
…
“Why Just Stop Eating Soy
Will Improve Your Health !!.”
"The Evidence Is In
-- Not Eating Soy Not Only Lowers The Risk and Helps Prevent
Breast Cancer, Leukemia & Other
Cancers Including The Reoccurrence of
Cancer, Soy Also Damages Your Thyroid, Nervous
System, Pancreas,
DNA, And Immune System.
Soy Also Causes Infertility, Cancer,
Heart and Liver Disease,
Hypospadia And Osteoporosis."
Just Revealing A Few Of The Almost 2
Dozen
Scientifically Documented
and Still
Ignored And Denied Very, Very
Serious Health Hazards
Since 1907
*
The Evidence
Soy Online Service … http://www.soyonlineservice.co.nz/ … Huge, extensive
scientific database, Soy Causes Cancer, etc.
Weston A Price Foundation … http://www.westonaprice.org/soy/index.html … Soy
Alert Page
The Whole Soy Story … http://www.thewholesoystory.com/index.php?pageID= … Book, April 2005, by Kaayla
Daniel, Ph.D
with 1,798 endnotes, scientific research
references and abstracts, since 1907 into 2005.
Soy - Abundance of Health Hazards … http://www.mayanmajix.com/art_ht.html … http://www.mayanmajix.com/soy.html …
Over 144 page Soy Research Paper, (
Oct. 2004 ), with 205 scientific research abstracts, since 1907 into
2004.
*
N.C.B.I. - Established in 1988 as a national resource for
molecular biology information, NCBI creates public databases, conducts research
in computational biology, develops software tools for analyzing genome data,
and disseminates biomedical information - all for the better understanding of
molecular processes affecting human health and disease.
PubMed - a service of the National Library of Medicine, includes over
15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and
additional life science journals.
PubMed includes links to many sites providing full text articles and other
related resources.
*Soy does not have
FDA GRAS status, Generally Recognized As Safe or Pre-market Approval ... is not legal to put in our food.
*Soy
industry applied twice to US FDA for GRAS and was turned down
twice, 1989 and 1999, because soy is carcinogenic.
*Genistein in soy is
proven to be and is scientifically classified as a Topoisomerase
II-poison … NCBI – PubMed.
*Soy proven a poisonous
plant since 1907 in US FDA Poisonous Plant database … http://www.cfsan.fda.gov/~djw/plantox.html.
*Violates “The Precautionary Principle” … http://www.biotech-info.net/rachels_586.html … “The obligation to prevent
harm”
Text
books - dangers of soy ...“Chemical Carcinogens” 1976, 1984, American
Chemical Society ...“Cancer Rates
& Risks” 4th Ed.1996, National Institutes of Health, National
Cancer Institute … “Hormonally Active
Agents in the Environment” 1999.
Be careful, be careful !!. “Vegetable Oil” has not
been real Vegetable Oil since early 1970’s. It is either soy, canola,
or both.
*Soy Protein – Is In Breach Of – In Violation
Of -- WHO/Codex Guidelines.
WHO/Codex General Standards for Soy Protein Products … http://www.soyonlineservice.co.nz/articles/Codex.htm .
There
is Clear evidence Soy Protein
does not meet WHO/Codex Guidelines.
Natural isoflavones in soy protein induce:
-- Sub acute
toxicity … http://www.soyonlineservice.co.nz/04thyroid.htm
… Repeated daily exposure to a poison
-- Chronic
toxicity … http://www.soyonlineservice.co.nz/articles/Brain.htm … Long term poisonous
health effects
-- Reproductive
toxicity … http://www.soyonlineservice.co.nz/04infertility.htm … Reproductive system
damage
-- Teratogenic
effects … http://www.soyonlineservice.co.nz/articles/Bdefects.htm … Embryo, monster making
-- Mutagenic
effects … http://www.soyonlineservice.co.nz/04immunefunction.htm …
Immune System and DNA Damage
… http://www.soyonlineservice.co.nz/articles/metzler.htm
.
WHO/Codex
Standard 175-1989.
6.3 (c) When
tested by appropriate methods of sampling and examination, the product shall not contain
other
poisonous substances which may represent a hazard to health.
WHO/Codex
General Guidelines for the Utilization of Vegetable Protein Products (VPP) in
Foods CAC/GL 4-1989.
4.1 VPP
intended for human consumption should not represent a hazard to health.
1.4 Toxicological
Safety:
Safety of the
VPP should be predicted from info. concerning methods of production, chemical
and physical properties...should be supported, where necessary, by safety data
using laboratory animals.
2.4.1 Sub
acute Toxicity Studies:
The purpose
of these studies is to delineate the toxic potential of VPP and to elucidate
such problems as species sensitivity, the nature of gross and
micro-pathological changes and the approximate dose level at which these
effects occur. They also provide
guidelines for the selection of dosage for chronic toxicity tests and any
functional or biochemical studies that may be necessary.
2.4.1.3 Length
of Study:
Sub acute toxicity feeding trials should be
at least three months duration.
2.4.2 Other
Studies:
Following an
appraisal of the source and the method of manufacture of the VPP together with
the results of nutritional and sub acute toxicity studies, the need for further
studies including chronic, reproduction, teratogenic and mutagenic studies will
be evaluated.
* *
*
New Margins – for pages 155 and 156
“Why Just Stop Eating Soy Will Improve Your
Health !!.”
By adjusting only pages 155 and 156 to these margins below, this
one page summary will all fit on one page in MS Word.
Top … 0.25 inches
Bottom … 0.25 inches
Left … 0.30 inches Right … 0.25 inches
Base Font Type … Times New Roman and Arial
Base Font Size … ( 8, 9,
10, 11, 14, 16, 20 ) , ( 10 pt for spacing between one line title and first
line )
( 8 pt for blank line spacing above - Soy
Protein – Is In Breach Of – In Violation Of -- WHO/Codex
Guidelines )
Justification … Left and full
Note: Make sure the label on your vitamins, minerals, medications
says … contains no Soy … or
… contains no Soy ingredients
.
Pet Food, farm animal foods
...
* *
*
* *
*
* *
*
Margins for main Soy Research Paper
Pages 1 to 144 , and ( through to 168 )
Top … 0.40 inches Base Font Type … Times New Roman and Arial
Bottom … 0.30 inches Base Font Size … ( 9, 10, 11, 12, 14, 16, 18, 20,
Left … 0.50 inches Right …
0.25 inches 22,24, 28, 30, 32, 36 )
Justification … Full
… … /
157
- 157 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
( Foods
with Vitamin B17 and B12 )
. .
Foods Containing Vitamin B-17 ( Nitrilosides )
. http://www.keepblairalive.com/b17foods.html .
. http://www.vitaminb17.org/foods.htm .
. http://www.realityzone.com/litcyancook.html .
.
Vitamin B17 appears in abundance in untamed
nature. Because B17 is bitter to the taste, in man's attempt to improve
tastes and flavors for his own pleasure, he has … eliminated bitter
substances like B17 … by
selection and cross-breeding. It
can be stated as a general rule that many of the foods that have been
domesticated still contain the vitamin B17 in that part not eaten by modem man,
such as the seeds in apricots. Listed below is an evaluation of some of
the more common foods. Keep in mind that these are averages only and that
specimens vary widely depending on variety, locale, soil, and climate. de Spain,
June - (former) FDA Toxicologist and Pharmacologist. "The Little Cyanide Cookbook" … http://www.amazon.com/exec/obidos/tg/detail/-/0912986190/103-8015284-4481409?v=glance … A professional nutritionist offers
over 300 tasty recipes rich in the cyanide containing substance that many
scientists believe is nature’s control for cancer. Cyanide, in minute
quantities and in proper food forms, instead of being poisonous, actually is
essential to health. 192-page book …
(+)plus Examples of dishonesty and corruption in the field of drug research …
a close look a the first major study which declared Laetrile - (vitamin B 17) -
“of no value” … proof that the study
was fraudulent … the FDA’s ruling
against the use of Laetrile because it had not been tested … and the refusal then to allow anyone ( except it
opponents ) to test it. This year over
550,000 Americans will die from cancer.
One out of 3 of us will develop cancer in our lifetime. The 88 million people in the USA alone. The purpose of this study is to show that
this great human tragedy can be stopped now entirely on the basis of existing
scientific knowledge.
Fruits … .. … … Range Seeds … Range Sprouts … Range
blackberry, domestic Low Apple seeds High Alfalfa
Medium
blackberry, wild High Apricot seeds High Bamboo
High
boysenberry Medium Buckwheat Mediuim Fava
Mediium
choke cherry High Cherry seed High Garbanzo
Mediium
wild crabapple High Flax Medium Mung
Medium
market cranberry Low Mullet Medium
Swedish (lignon) cranberry High Nectarine seed High
Currant Medium Peach seed High
Elderberry Med. to High Pear
seed High
Gooseberry & Huckleberry Med..
Loganberry
Med. Prune seed High
Mulberry Med. Squash Mediium
Quince Med. Strawberries Med.
Raspberry and Strawberry Med Palmigranits . ??
Beans … … Range Beans … …
Range Leaves
... Range
Black Low Lentals Medium Alfalfa High
Black-eyed peas Low to Medium Lima, USA Low Beet tops
Low
Fava High
Garbanzo Low to Medium Mung Med. to High Spinach
Low
Green Pea Low Shell Low Watercress
Low
Kidney Low to
Medium
Range Tubers … Range Nuts … … Range
1,000 mg ( Milligrams ) = 1
gram Cassava
High Bitter Almond
High
High — above 500 mgs. nitriloside per
100 grams food Sweet Potato
Low Cashew Low
Medium — above 100 mgs. nitriloside per
100 grams food Yams Low Macadamia
Med to High
Low — below 100 mgs. nitriloside per
100 grams food
...
/ 158
- 158 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
( Foods
with Vitamin B17 and B12 )
What Is Vitamin B12 ??.
Foods Containing Vitamin B-12, (Cobalamin)
Signs, symptoms, health
problems with vitamin B12 deficiency
xx. http://ods.od.nih.gov/factsheets/vitaminb12.asp
.
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5
.
. http://lpi.oregonstate.edu/infocenter/vitamins/vitaminB12/ .
.
Vitamin B12 is naturally found in animal foods including fish, meat, poultry, eggs, milk, and milk products. Fortified breakfast cereals are a particularly valuable source of vitamin B12 for vegetarians [5-7]. Table 1 lists a variety of food sources of vitamin B12.
.
. Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
.
Table of Contents
What foods provide vitamin B12?
What is the recommended dietary intake for vitamin B12?
When is a deficiency of vitamin B12 likely to occur?
Do pregnant and/or lactating women need extra Vitamin B12?
Who else may need a vitamin B12 supplement to prevent a deficiency?
Caution: Folic Acid and vitamin B12 deficiency
What is the relationship between vitamin B12 homocysteine, and cardiovascular disease?
Do healthy young adults need a vitamin B12 supplement?
What is the health risk of too much vitamin B12?
.
What is vitamin B12?
Vitamin B12 is also
called cobalamin because it contains the metal cobalt. This vitamin helps
maintain healthy nerve cells and red blood cells [1-4]. It is
also needed to help make DNA, the genetic material in all cells [1-4].
Vitamin B12 is bound to the protein in food. Hydrochloric acid in
the stomach releases B12 from proteins in foods during digestion.
Once released, vitamin B12 combines with a substance called gastric
intrinsic factor (IF). This complex can then be absorbed by the intestinal
tract.
. ...
/ 159
- 159 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
What foods provide vitamin B12?
Vitamin B12 is
naturally found in animal foods including fish, meat, poultry, eggs, milk, and
milk products. Fortified breakfast cereals are a particularly valuable source
of vitamin B12 for vegetarians [5-7]. Table
1 lists a variety of food sources of vitamin B12.
Table 1: Selected food sources of vitamin B12 [5]
|
Food |
Micrograms (μg) |
Percent |
|
Mollusks,
clam, mixed species, cooked, 3 ounces |
84.1 |
1400 |
|
Liver,
beef, braised, 1 slice |
47.9 |
780 |
|
Fortified
breakfast cereals, (100%) fortified), ¾ cup |
6.0 |
100 |
|
Trout,
rainbow, wild, cooked, 3 ounces |
5.4 |
90 |
|
Salmon,
sockeye, cooked, 3 ounces |
4.9 |
80 |
|
Trout,
rainbow, farmed, cooked, 3 ounces |
4.2 |
50 |
|
Beef, top
sirloin, lean, choice, broiled, 3 ounces |
2.4 |
40 |
|
Fast
Food, Cheeseburger, regular, double patty & bun, 1 sandwich |
1.9 |
30 |
|
Fast
Food, Taco, 1 large |
1.6 |
25 |
|
Fortified
breakfast cereals (25% fortified), ¾ cup |
1.5 |
25 |
|
Yogurt,
plain, skim, with 13 grams protein per cup, 1 cup |
1.4 |
25 |
|
Haddock,
cooked, 3 ounces |
1.2 |
20 |
|
Clams,
breaded & fried, ¾ cup |
1.1 |
20 |
|
Tuna,
white, canned in water, drained solids, 3 ounces |
1.0 |
15 |
|
Milk, 1
cup |
0.9 |
15 |
|
Pork,
cured, ham, lean only, canned, roasted, 3 ounces |
0.6 |
10 |
|
Egg,
whole, hard boiled, 1 |
0.6 |
10 |
|
American
pasteurized cheese food, 1 ounces |
0.3 |
6 |
|
Chicken,
breast, meat only, roasted, ½ breast |
0.3 |
6 |
.
*DV = Daily
Value. DVs are
reference numbers developed by the Food and Drug Administration (FDA) to help
consumers determine if a food contains a lot or a little of a specific
nutrient. The DV for vitamin B12 is 6.0 micrograms (μg). Most
food labels do not list a food's vitamin B12 content. The percent DV
(%DV) listed on the table indicates the percentage of the DV provided in one
serving. A food providing 5% of the DV or less is a low source while a food
that provides 10-19% of the DV is a good source. A food that provides 20% or
more of the DV is high in that nutrient. It is important to remember that foods
that provide lower percentages of the DV also contribute to a healthful diet.
For foods not listed in this table, please refer to the U.S. Department of
Agriculture's Nutrient Database Web site: http://www.nal.usda.gov/fnic/cgi-bin/nut_search.pl.
Continued … ...
/ 160
- 160 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
.
What is the
recommended dietary intake for vitamin B12?
Recommendations for vitamin B12 are provided in
the Dietary Reference Intakes (DRIs) developed by the
Table 2: Recommended Dietary Allowances (RDA) for vitamin B12
for children and adults [7]
|
Age |
Males and Females |
Pregnancy |
Lactation |
|
1-3 |
0.9 |
N/A |
N/A |
|
4-8 |
1.2 |
N/A |
N/A |
|
9-13 |
1.8 |
N/A |
N/A |
|
14-18 |
2.4 |
2.6 |
2.8 |
|
19 and older |
2.4 |
2.6 |
2.8 |
There is insufficient information on vitamin B12 to establish a RDA
for infants. Therefore, an Adequate Intake (AI) has been established that is
based on the amount of vitamin B12 consumed by healthy infants who
are fed breast milk [7]. Table 3
lists the Adequate Intakes for vitamin B12, in micrograms (μg),
for infants.
Table 3: Adequate Intake for vitamin B12 for infants [7]
|
Age |
Males and Females |
|
0-6 months |
0.4 |
|
7-12 months |
0.5 |
Continued … ...
/ 161
- 161 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
When is a deficiency
of vitamin B12 likely to occur?
Results of two national surveys, the National Health and
Nutrition Examination Survey (NHANES III-1988-94) [8] and the
Continuing Survey of Food Intakes by Individuals (CSFII 1994-96) found that
most children and adults in the United States (U.S.) consume recommended
amounts of vitamin B12 [6-8]. A
deficiency may still occur as a result of an inability to absorb B12
from food and in strict vegetarians who do not consume any animal foods [9]. As a
general rule, most individuals who develop a vitamin B12 deficiency
have an underlying stomach or intestinal disorder that limits the absorption of
vitamin B12 [10].
Sometimes the only symptom of these intestinal disorders is subtly reduced
cognitive function resulting from early B12 deficiency. Anemia and
dementia follow later [1,11].
Signs, symptoms, and health problems associated with
vitamin B12 deficiency
· Characteristic signs, symptoms, and health problems associated with B12 deficiency include anemia, fatigue, weakness, constipation, loss of appetite, and weight loss [1,3,12].
· Deficiency also can lead to neurological changes such as numbness and tingling in the hands and feet [7,13].
· Additional symptoms of B12 deficiency are difficulty in maintaining balance, depression, confusion, dementia, poor memory, and soreness of the mouth or tongue [14].
· Signs of vitamin B12 deficiency in infancy include failure to thrive, movement disorders, delayed development, and megaloblastic anemia [15].
Many of these symptoms are very general and can result from a variety of
medical conditions other than vitamin B12 deficiency. It is
important to have a physician evaluate these symptoms so that appropriate
medical care can be given.
Do pregnant and/or lactating women need extra
Vitamin B12?
During pregnancy, nutrients
travel from mother to fetus through the placenta. Vitamin B12, like
other nutrients, is transferred across the placenta during pregnancy.
Breast-fed infants receive their nutrition, including vitamin B12,
through breast milk. Vitamin B12 deficiency in infants is rare but
can occur as a result of maternal insufficiency [15]. For
example, breast-fed infants of women who follow strict vegetarian diets have
very limited reserves of vitamin B12 and can develop a vitamin B12
deficiency within months of birth [7,16]. This
is of particular concern because undetected and untreated vitamin B12
deficiency in infants can result in permanent neurologic damage. Consequences
of such neurologic damage are severe and can be irreversible. Mothers
who follow a strict vegetarian diet should consult with a pediatrician
regarding appropriate vitamin B12 supplementation for their infants
and children [7]. They
should also discuss their own need for vitamin B12 supplementation
with their personal physician.
Continued … ...
/ 162
- 162 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
Who else may need a Vitamin B12 supplement to prevent a
deficiency ??.
· Individuals with pernicious anemia or gastrointestinal disorders may benefit from or require a vitamin B12 .
· Older adults and vegetarians may benefit from a vitamin B12 supplement or an increased intake of foods fortified with vitamin B12.
· Some medications may decrease absorption of
vitamin B12. Chronic use of those medications may result in a need
for supplemental B12.
Individuals with
pernicious anemia
Anemia is a condition that occurs when there is insufficient hemoglobin in red
blood cells to carry oxygen to cells and tissues. Common signs and symptoms of
anemia include fatigue and weakness. Anemia can result from a variety of
medical problems, including deficiencies of vitamin B12, vitamin B6,
folate and iron. Pernicious anemia is the name given more than a century ago to
describe the then-fatal vitamin B12 deficiency anemia that results
from severe gastric atrophy, a condition that prevents gastric cells from
secreting intrinsic factor. Intrinsic factor is a substance normally present in
the stomach. Vitamin B12 must bind with intrinsic factor before it
can be absorbed and used by your body [7,17-18]. An
absence of intrinsic factor prevents normal absorption of B12 and
results in pernicious anemia.
Most individuals with pernicious anemia need parenteral (deep subcutaneous)
injections (shots) of vitamin B12 as initial therapy to replenish
depleted body B12 stores. Body stores of vitamin B12 can
then be managed by a daily oral supplement of B12. A physician will
manage the treatment required to maintain the vitamin B12 status of
individuals with pernicious anemia.
Individuals with
gastrointestinal disorders
Individuals with stomach and small intestinal disorders may be unable to absorb
enough vitamin B12 from food to maintain healthy body stores [19].
Intestinal disorders that may result in malabsorption of vitamin B12
include:
- Sprue, often referred to as Celiac Disease (CD), is a genetic disorder. People with CD are intolerant to a protein called gluten. In CD, gluten can trigger damage to the small intestines, where most nutrient absorption occurs. People with CD often experience nutrient malabsorption. They need to follow a gluten free diet to avoid malabsorption and other symptoms of CD.
- Crohn's Disease is an inflammatory bowel disease that affects the small intestines. People with Crohn's disease often experience diarrhea and nutrient malabsorption.
- Surgical procedures in the gastrointestinal tract, such as surgery to remove all or part of the stomach, often result in a loss of cells that secrete stomach acid and intrinsic factor [7,20-21]. Surgical removal of the distal ileum, a section of the intestines, also can result in the inability to absorb vitamin B12. Anyone who has had either of these surgeries usually requires lifelong supplemental B12 to prevent a deficiency. These individuals would be under the routine care of a physician, who would periodically evaluate vitamin B12 status and recommend appropriate treatment.
.Continued … ...
/ 163
- 163 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
Who else may need a Vitamin B12 supplement to prevent a
deficiency ??.
Continued …
Older adults
Gastric acid helps release vitamin B12 from the protein in food.
This must occur before B12 binds with intrinsic factor and is
absorbed in your intestines. Atrophic gastritis, which is an inflammation of
the stomach, decreases gastric secretion. Less gastric acid decreases the
amount of B12 separated from proteins in foods and can result in
poor absorption of vitamin B12 [10,22-26].
Decreased gastric secretion also results in overgrowth of normal bacterial
flora in the small intestines. The bacteria may take up vitamin B12
for their own use, further contributing to a vitamin B12 deficiency
[27].
Up to 30 percent of adults 50 years and older may have atrophic gastritis, an
overgrowth of intestinal flora, and be unable to normally absorb vitamin B12
in food. They are, however, able to absorb the synthetic B12 added
to fortified foods and dietary supplements. Vitamin supplements and fortified
foods may be the best sources of vitamin B12 for adults over the age
of 50 [7].
Researchers have long been interested in the potential connection between vitamin B12 deficiency and dementia [28]. A recent review examined correlations between cognitive skills, homocysteine levels, and blood levels of folate, vitamin B12 and vitamin B6. The authors suggested that vitamin B12 deficiency may decrease levels of substances needed for the metabolism of neurotransmitters [29]. Neurotransmitters are chemicals that transmit nerve signals. Reduced levels of neurotransmitters may result in cognitive impairment. In 142 individuals considered at risk for dementia, researchers found that a daily supplement providing 2 milligrams (mg) folic acid and 1 mg B12, taken for 12 weeks, lowered homocysteine levels by 30%. They also demonstrated that cognitive impairment was significantly associated with elevated plasma total homocysteine. However, the decrease in homocysteine levels seen with vitamin supplementation did not improve cognition [30]. It is too soon to make any recommendations, but is an intriguing area of research.
Vegetarians
The popularity of vegetarian diets has risen along with an interest in avoiding
meat and meat products for environmental, philosophical, and health reasons.
However, the term vegetarianism is subject to a wide range of interpretations.
Some people consider themselves to be vegetarian when they avoid red meat.
Others believe that vegetarianism requires avoidance of all animal products,
including meat, poultry, fish, eggs, and dairy foods. The most commonly
described forms of vegetarianism include:
· "Lacto-ovo vegetarians", who avoid meat, poultry, and fish products but consume eggs and dairy foods
· "Strict vegetarians", who avoid meat, poultry, fish, eggs, and dairy foods
· "Vegans", who avoid meat, poultry, fish, eggs, and dairy foods but also do not use animal products such as honey, leather, fur, silk, and wool
Continued … ...
/ 164
- 164 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
Who else may need a Vitamin B12 supplement to prevent a
deficiency ??.
Continued …
Vegetarians
Continued
Strict vegetarians and vegans are at greater risk of developing vitamin B12 deficiency than lacto-ovo vegetarians and non-vegetarians because natural food sources of vitamin B12 are limited to animal foods [7]. Fortified cereals are one of the few sources of vitamin B12 from plants, and are an important dietary source of B12 for strict vegetarians and vegans. Strict vegetarians and vegans who do not consume plant foods fortified with vitamin B12 need to consider taking a dietary supplement that contains vitamin B12 and should discuss the need for B12 supplementation with their physician.
There is wide belief that vitamin B12 can be consistently obtained from nutritional yeasts. Consumers should be aware that these products may or may not contain added nutrients such as vitamin B12. Dietary supplements are regulated as foods rather than drugs, and companies that sell supplements such as nutritional yeasts fortified with vitamin B12 can legally change their formulation at any time. If you choose to supplement, select reliable sources of vitamin B12 and read product labels carefully.
.
When adults adopt a strict vegetarian diet, deficiency symptoms can be slow to appear. It may take years to deplete normal body stores of B12. However, breast-fed infants of women who follow strict vegetarian diets have very limited reserves of vitamin B12 and can develop a vitamin B12 deficiency within months [7]. This is of particular concern because undetected and untreated vitamin B12 deficiency in infants can result in permanent neurologic damage. Consequences of such neurologic damage are severe and can be irreversible. There are many case reports in the literature of infants and children who suffered consequences of vitamin B12 deficiency. It is very important for mothers who follow a strict vegetarian diet to consult with a pediatrician regarding appropriate vitamin B12 supplementation for their infants and children [7].
.
Continued …
...
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Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
Table 4 summarizes
several drugs that potentially influence vitamin B12 absorption.
Table 4: Important vitamin B12/drug interactions
|
Drug |
Potential Interaction |
|
· Proton
Pump Inhibitors (PPIs) are used to treat gastroesophageal reflux
disease (GERD) and peptic ulcer disease. Examples of PPIs are Omeprazole
(Prilosec©) and Lansoprazole (Prevacid©) |
PPI medications can interfere with vitamin B12
absorption from food by slowing the release of gastric acid into the stomach
[31-33].
This is a concern because acid is needed to release vitamin B12
from food prior to absorption. So far, however, there is no evidence that
these medications promote vitamin B12 deficiency, even after
long-term use [34]. |
|
· H2
receptor antagonists are used to treat peptic ulcer disease.
Examples are Tagament©, Pepsid©, and Zantac© |
H2 receptor antagonists can interfere with vitamin B12
absorption from food by slowing the release of gastric acid into the stomach.
This is a concern because acid is needed to release vitamin B12
from food prior to absorption. So far, however, there is no evidence that
these medications promote vitamin B12 deficiency, even after
long-term use [34]. |
|
· Metformin©
is a drug used to treat diabetes. |
Metformin© may interfere with calcium metabolism [35].
This may indirectly reduce vitamin B12 absorption because vitamin
B12 absorption requires calcium [35].
Surveys suggest that from 10% to 30% of patients taking Metformin© have
evidence of reduced vitamin B12 absorption [35]. |
.
In a study involving 21 subjects
with type 2 diabetes, researchers found that 17 who were prescribed Metformin©
experienced a decrease in vitamin B12 absorption. Researchers also
found that supplementation with calcium carbonate (1200 milligrams per day)
helped limit the effect of Metformin© on vitamin B12 absorption in
these individuals [35].
Although these medications may interact with the absorption of vitamin B12,
they are necessary to take for certain conditions. It is important to consult
with a physician and registered dietitian to discuss the best way to maintain
vitamin B12 status when taking these medications.
Continued …
...
/ 166
- 166 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
Caution: Folic Acid and vitamin B12
deficiency
Folic acid can correct the anemia that is caused by vitamin B12 deficiency. Unfortunately, folic acid will not correct the nerve damage also caused by B12 deficiency [1,36]. Permanent nerve damage can occur if vitamin B12 deficiency is not treated. Folic acid intake from food and supplements should not exceed 1,000 micrograms (μg) daily in healthy individuals because large amounts of folic acid can trigger the damaging effects of vitamin B12 deficiency [7]. Adults older than 50 years who take a folic acid supplement should ask their physician or qualified health care provider about their need for vitamin B12 supplementation.
What is the
relationship between vitamin B12 homocysteine, and cardiovascular
disease?
Cardiovascular disease involves
any disorder of the heart and blood vessels that make up the cardiovascular
system. Coronary heart disease occurs when blood vessels which supply the heart
become clogged or blocked, increasing the risk of heart attack. Vascular damage
can also occur to blood vessels supplying the brain, can result in a stroke.
Cardiovascular disease is the most common cause of death in industrialized
countries such as the
Vitamin B12, folate,
and vitamin B6 are involved in homocysteine metabolism. In fact, a
deficiency of vitamin B12, folate, or vitamin B6 may
increase blood levels of homocysteine. Recent studies found that supplemental
vitamin B12 and folic acid decreased homocysteine levels in subjects
with vascular disease and in young adult women. The most significant drop in
homocysteine level was seen when folic acid was taken alone [48-49]. A
significant decrease in homocysteine levels also occurred in older men and
women who took a multivitamin/ multimineral supplement for 56 days [50]. The
supplement taken provided 100% of Daily Values (DVs) for nutrients in the
supplement.
Evidence supports a role for supplemental folic acid and vitamin B12
for lowering homocysteine levels, however this does not mean that these
supplements will decrease the risk of cardiovascular disease. Clinical
intervention trials are underway to determine whether supplementation with
folic acid, vitamin B12, and vitamin B6 can lower risk of
coronary heart disease. It is premature to recommend vitamin B12
supplements for the prevention of heart disease until results of ongoing
randomized, controlled clinical trials positively link increased vitamin B12
intake from supplements with decreased homocysteine levels AND decreased risk
of cardiovascular disease.
Continued … ...
/ 167
- 167 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Dietary Supplement Fact Sheet: Vitamin B12
. http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5 .
Continued
.
Do healthy young adults need a vitamin
B12 supplement?
It is generally accepted that older adults are at greater risk of developing a vitamin B12 deficiency than younger adults. One study, however, suggests that the prevalence of B12 deficiency in young adults may be greater than previously thought. This study found that the percentage of subjects in three age groups (26 to 49y, 50 to 64y, and 65y and older) with deficient blood levels of vitamin B12 was similar across all age groups but that symptoms of B12 deficiency were not as apparent in younger adults. This study also suggested that those who did not take a supplement containing vitamin B12 were twice as likely to be B12 deficient as supplement users, regardless of age group. However, non-supplement users who consumed fortified cereal more than 4 times per week did appear to be protected from deficient blood levels of B12. Better tools and standards to diagnose B12 deficiencies are needed to make specific recommendations about the appropriateness of vitamin B12 supplements for younger adults [51].
What is the health
risk of too much vitamin B12?
The
.
53 - References … go to the end of this
article … http://ods.od.nih.gov/factsheets/vitaminb12.asp#en5#en5
.
.
...
/ 168
- 168 -
Dangers of Dietary Isoflavones
at levels above those found in traditional
diets
The Risks Of Abandoning “The Precautionary
Principle”
by Soy Online Service … http://www.soyonlineservice.co.nz/
“Soy
- Abundance Of Health Hazards” … http://www.mayanmajix.com/soy01.html
Some Common Alkaline Ash Foods
{ Helps To
Control Acid In Your Internal Environment }
Eat 80 %
alkaline foods, un-cooked.
. .
Almonds Grape fruit Papaya
- ( Papuan enzyme + B-17 )
Apricots - ( seeds + B-17 ) Grapes Parsnips
Apples - ( seeds + B-17 ) Green
beans Peaches
- ( seeds + B-17 )
Apple cider Vinegar
Green Peas Pears
appreciation Pineapple,
½ a day, ( Bromelain enzyme )
Avocados Herbs - ( some of them ) Potatoes, sweet - ( B-17 )
Herbal teas - ( with no caffeine ) Potatoes , white ***
Bananas Honey
Beans, dried - ( B-17 ) Quinoa
***
( Soybeans and Soy
are all acid, Avoid Soy ) joy
( Soy is a proven poison
& blocks
absorption
of B17 )
Beet greens Juice - (fresh, raw) Radishes
Beets Raisins
Blackberries - ( B-17 ) Lemons Raspberries - ( B-17 )
Broccoli
Lettuce Rhubarb
** - ( not recommended )
Brussels sprouts Lima beans *** - ( dried and green ) Rutabagas
Limes
Cabbage love Sauerkraut
Carrots Spinach,
raw
Cauliflower Maple syrup Strawberries
- ( B-17 )
Celery Milk - goats * - ( infants only )
Chard leaves Melons Tangerines
Cherries, sour - (seeds, B-17) Millet *** - ( B-17 ) Tomatoes
Cucumbers Molasses
Mushrooms Vegetables,
raw
Dates, dried Muskmelons
Dulse Watercress
Nuts - ( not soy ) Watermelon
Figs, dried ( Soy is a proven poison & blocks absorption of B17 )
Fresh Fruit - ( organic ) Onions Pesticides turn food from alkaline
to acid and
(
no pesticides ) Oranges
make
acid food more acid.
Fun
Olive oil - ( organic, cold pressed ) Do not mix citrus or melons with
any other food
*
* *
Vitamin B-17 ... found is seeds of all common fruits (except citrus), it is an anti-cancer vitamin.
* Recommended for infants only when
mother’s milk is not available
** Not recommended, has properties
detrimental to the body
*** These foods slow down the cleansing process, reduce
amount of plague removed, therefore should be limited
“Alkalize for Health, (Stop the cancer epidemic)”… http://www.alkalizeforhealth.net/
,
http://www.alkalizeforhealth.net/tableofcontents.htm
,
“Live Blood Cell
Analysis and the SanPharma Remedies”,
with a list of some ”Alkaline Foods“ at
...
- http://www.medical-library.net/specialties/framer.html?/specialties/_live_blood_cell_analysis.html .